| 1. |
Jiro Nakayama, Asian Microbiome Project to understand the current status of gut microbial community of Asians as an interface between foods
and health, The 12th Asian Conference on Lactic Acid Bacteria, 2021.10. |
| 2. |
Jiro Nakayama, Interaction of diet and gut microbiome in Asians and its effect on their health, 22nd International Union of Nutritional Sciences, 2022.11. |
| 3. |
Jiro Nakayama, Gut microbiome and metabolome of Asian population related to diet and health, The 11th Asian Conference on Lactic Acid Bacteria, 2021.11. |
| 4. |
Akari SHINODA, Shirchin DEMBEREL, Riko MISHIMA, Dugersuren JAMYAN, Tsogtbaatar LKHAGVAJAV , Jiro NAKAYAMA, Comparison of gut microbiota between diabetic and non-diabetic obese Mongolian, The 11th Asian Conference on Lactic Acid Bacteria, 2021.11. |
| 5. |
Effect of glycosylceramide on the intestinal bacteria in vitro. |
| 6. |
Jiro Nakayama, Gut microbiome and metabolome of Asians associated with diets and health, The 6th International Conference of Indonesian Society for Lactic Acid Bacteria and Gut Microbiota, 2021.08. |
| 7. |
Riko Mishima, Masafumi Sanefuji, Seiichi Morokuma, Masaru Tanaka, Masanobu Ogawa, Kiyoko Kato, Jiro Nakayama, The succession of gut mycobiota in Japanese infants at first 3 years of life, International Union of Microbiological Societies 2020, 2020.10. |
| 8. |
Phatthanaphong Therdtatha, Masaru Tanaka, Mariyatun Mariyatun, Miisaroh Almunifah, Nancy Eka Putri Manurung, Siska Indriarshi, Yuan-kun, Lee, Endang Sutriswati Rahayu, Jiro Nakayama, Difference of Gut Microbial Community in Indonesian Obese, Type 2 Diabetic, and Healthy Groups, 日本農芸化学会２０２０年度大会, 2020.03. |
| 9. |
Yayi Song, Phatthanaphong Therdtatha, Masaru Tanaka, Mariyatun Mariyatun, Miisaroh Almunifah, Nancy Eka Putri Manurung, Siska Indriarshi, Yuan-kun, Lee, Endang Sutriswati Rahayu, Jiro Nakayama, Difference of Gut Microbial Metabolism among Indonesian Obese, Type 2 Diabetic, and Healthy Groups, 日本農芸化学会２０２０年度大会, 2020.03. |
| 10. |
Jiro Nakayama, Features and signatures in Asian microbiome: Crisis or adaptation ?, The 10th Asian Conference on Lactic Acid Bacteria, 2019.08. |
| 11. |
＃Masaru Tanaka, M. Sanefuji, S. Morokuma, M. Yoden, R. Momoda, K. Sonomoto, K. Kato, J. Nakayama, Maturation of the infant gut microbiota community and bile acids metabolism over three years in healthy Japanese infants, 7th Beneficial Microbes Conference, 2018.11. |
| 12. |
Misato Horino, M. Tanaka, A. Uchikawa, R. Momoda, K. Sonomoto, Y. Ogura, A. Toyoda, T. Yamada, K. Kurokawa, T. Hayashi, J.Nakayama, Signatures imprinted in gut microbiome of Asians: a comparative metagenomic study of children in East and South-East Asia, 7th Beneficial Microbes Conference, 2018.11. |
| 13. |
Jiro Nakayama, Introduction of Asian Microbiome Project: Comparative gut microbiome study within and across countries, Bio Japan 2018, 2018.10. |
| 14. |
J. Kisuse, M. Tanaka, P. Therdtatha, R. Momoda, O. La-ongkham, M. Nakphaichit, S. Nitisinpraser, S. Fukuda, K. Sonomoto, J. Nakayama, Urbanization of Thai diets and its impacts to children gut microbiota and metabolites, The International Conference on
Beneficial Microbes, ICOBM2018, 2018.08. |
| 15. |
Juma Kisuse, Masaru Tanaka, Ayaka Uchikawa, Misako Yoden, Rie Momoda, Kenji Sonomoto, Jiro Nakayama, Comparative study on the link between diet and gut microbiota in rural and urban children in Thailand, International Symposium on Agricultural, Food, Environmental and Life Sciences in Asia, 2017.11. |
| 16. |
Keika Adachi, Jiro Nakayama., Metabolic-linked pH-drop quenches VirSR quorum sensing in Clostridium perfringens, 6th ASM Cell-Cell communication in Bacteria, 2017.10. |
| 17. |
Jiro Nakayama, Ecology of gut microbiota in Japanese children - possible link with pre- and probiotics research
, 6th Beneficial Microbes Conference, 2017.10. |
| 18. |
Jiro Nakayama, Changing dietary habit is changing Asians gut microbiota
, 15th International Congress of Bacteriology and Applied Microbiology, 2017.07, Objective: The impact of modernization in life style on the health of human is global issue at present. Particularly, westernization of diets links to certain diseases in developing area. Recent some studies have revealed that gut microbiota altered by the introduction of Western foods is involved in the increase of risk for certain diseases, e.g., colon cancer, obesity, or diabetes. Our international consortium project, Asian Microbiome Project, has also investigate the impact of globalization of diets on the gut microbial community in Asian population.
Methods:
Leyte island in Philippines is being modernized and children in the rural Baybay city and urban Ormoc city have different life style including daily diets. To know the impact of modernization of dietary habit on gut microbiota in preadolescent children, we compared fecal microbiota between Baybay (n=23) and Ormoc children (n=19) at the age of 7 to 9 years old and examined the correlation of bacterial composition with their dietary data.
Results:
Dietary survey indicated that Ormoc children consumed significantly higher level of fat than Baybay children, by eating modern high-fat foods. Fecal microbiota was analyzed by meta 16S rRNA analysis with the dataset of other five Asian countries. Their microbiota at family level were grouped into two enterotype-like clusters, each defined by the high abundance of Prevotellaceae (P-type) and Bacteroidaceae (BB-type), respectively. Baybay and Ormoc children mainly harbored P-type and BB-type, respectively. Redundancy analysis with their dietary nutrients showed that P-type and BB-type favors carbohydrate and fat, respectively. Fat intake level correlated positively with Firmicutes-to-Bacteroidetes (F/B) ratio and negatively with relative abundance of genus Prevotella. Overweight and obese children who were living in Ormoc and took higher level of fat, harbored the microbiota with higher F/B ratio and lower abundance of Prevotella. The altered gut microbiota may be a sign of modern diet-induced obesity among children in developing areas.
Conclusion:
Oriental and Western dietary cultures are now mixing in Asia and remodeling gut microbiota of Asians. To ensure our healthiness in feature, it should be important to understand the link between diets, gut microbiota, and health, in more depth.. |
| 19. |
Jiro Nakayama, Changing dietary habit is changing Asian gut microbiota, 5th Beneficial Microbes Conference, 2016.10. |
| 20. |
Sunee Nitisinprasert, Orawan La-ongkam, Supatjaree Ruengsomwong, Massalin Nakphaichit, Bhusita Wanissorn, Jiro Nakayama, Age-related changes and their food consumption affecting gut microbiota of healthy Thai subjects, 第67回日本生物工学会, 2015.10. |
| 21. |
Jiro Nakayama, Digging into our gut microbial community by NGS, 2nd Asian Fermented Foods: Probiotic: the potential ingredients for health products, 2015.08. |
| 22. |
Jiro Nakayama, What is microbiota, microbiome and their analysis ?, The 8th Asian Conference on Lactic Acid Bacteria, 2015.07. |
| 23. |
Ravindra Pal Singh, Kenich Okubo, Kenji Sonomoto, Jiro Nakayama, Development of quorum quenching peptides targeting VirR/VirS system of Clostridium perfringens, 6th Congress of European Microbiologists, 2015.06. |
| 24. |
Jiro Nakayama, Yuan Kun Lee, Asian Microbiome Project: Diversity in gut microbiota of Asian people, 4th Beneficial Microbes Conference, 2015.03. |
| 25. |
Ravindra Pal Singh, Kaori Ohtani, Ryoji Yokohata, Kenji Sonomoto, Toru Shimizu, Jiro Nakayama, Identification of autoinducing peptide of Clostridium perfringens and development of its inhibitors, 5th AMS conference on cell-cell communication in bacteria, 2014.10. |
| 26. |
Jihaui Jiang, Kenji Sonomoto, Jiro Nakayama, Diversity in gut bacterial composition and their 16S rRNA gene sequences among Asian children, 第37回講演会（日本農芸化学会関西・中四国・西日本支部、日本ビタミン学会近畿・中四国・九州沖縄合同大会, 2013.09. |
| 27. |
Jiang J, Nakayama J, Watanabe K, Sakamoto N, Matsuda K, Kurakawa T, Tsuji H, Ren FZ, Nitisinprasert S, Rahayu ES, Liao CC, Tsai YC, Lee YK, 454 Pyrosequencing study on the basal microbiota of healthy Asian youngsters, 3rd Asain Symposium on Lactic Acid Bacteria, 2012.05. |
| 28. |
Jiro Nakayama, Yuki Korenori, Takako Kobayashi, Kenji Sonomoto, Community structure of developmental GI tract microbiota in infants and
its correlation with allergy development in later life, 3rd TNO beneficial microbes conference, 2012.03. |
| 29. |
Nakayama J, Watanabe K, Sakamoto N, Jiang J, Matsuda K, Kurakawa T, Tsuji H, Ren FZ, Nitisinprasert S, Rahayu ES, Liao CC, Tsai YC, Lee YK, Asian Microbiome Project: A pilot study on the basal microbiota profile of healthy Asian youngsters, International Human Microbiome Conference, 2012.03. |
| 30. |
Jiro Nakayama, Yuki Korenori, Takako Kobayashi, Kenji Sonomoto, Community structure of developmental GI tract microbiota in infants and
its correlation with allergy development in later life, 3rd TNO beneficial microbes conference, 2012.03. |
| 31. |
Jiro Nakayama, Discovery and Development of Inhibitors Targeting Cyclic Peptide-mediated Quorum Sensing in Gram-positive Pathogens, 4th ASM conference on cell-cell communication in bacteria, 2011.11. |
| 32. |
Kenji Sonomoto, Takeshi Zendo, Jiro Nakayama, BACTERIOCINS OF LACTIC ACID BACTERIA: NEW APPLICATIONS AND PRODUCTION, International Union of Microbiological Societies 2011 Congress, 2011.09. |
| 33. |
Jiro Nakayama, COMMUNITY STRUCTURE AND IMMUNE FUNCTION OF DEVELOPMENTAL GI TRACT
MICROBIOTA IN INFANTS, International Union of Microbiological Societies 2011 Congress, 2011.09. |
| 34. |
Said E Desouky, Yasuhiro Igarashi, Paul Williams,
Kenji Sonomoto, Jiro Nakayama, SCREENING OF ANTIPATHOGENIC AGENTS TARGETING
CYCLIC PEPTIDES-MEDIATED QUORUM SENSING OF
GRAM-POSITIVE BACTERIA, International Union of Microbiological Societies 2011 Congress, 2011.09. |
| 35. |
Tijo Varghese Puramattathu, Mohammad R. Islam,
Mami Nishie, Sae Yanagihara, Jun-Ichi Nagao,
Ken-Ichi Okuda, Takeshi Zendo, Jiro Nakayama,
Kenji Sonomoto, ENHANCED NUKACIN D13E PRODUCTION IN
LACTOCOCCUS LACTIS NZ9000 BY THE ADDITIONAL
EXPRESSION OF IMMUNITY GENES, International Union of Microbiological Societies 2011 Congress, 2011.09. |
| 36. |
Rodney H Perez, Naoki Ishibashi, Kohei Himeno, Takeshi Zendo, Jiro Nakayama,
Kenji Sonomoto, INVESTIGATION OF THE REGULATION MECHANISM OF MULTIPLE BACTERIOCIN
PRODUCTION IN ENTEROCOCCUS FAECIUM NKR-5-3 USING A DEVELOPED ESI-LC/MS
SYSTEM, International Union of Microbiological Societies 2011 Congress, 2011.09. |
| 37. |
Jiro Nakayama, COMMUNITY STRUCTURE AND IMMUNE FUNCTION OF DEVELOPMENTAL GI TRACT
MICROBIOTA IN INFANTS, International Union of Microbiological Societies 2011 Congress, 2011.09. |
| 38. |
Yuan Kun Lee, Jiro Nakayama, Fazheng Ren, Sunee Nitisinprasert, Endang Rahayu,
Raha Abdul Rahim, Chii Cherng Liao, Koichi Watanabe, Ying Chieh Tsai, ASIAN MICROBIOME PROJECT, International Union of Microbiological Societies 2011 Congress, 2011.09. |
| 39. |
Sunee Nitisinprasert, Massalin Nakphaichit, Nuntaporn Pungsungvorn,
Jiraporn Tangthong, Arpa Suwatwattanakul, Jiro Nakayama, Kenji Sonomoto, AN OVERVIEW OF LACTOBACILLUS REUTERI KUB-AC5
AS AN ANTIMICROBIAL SUBSTANCE PRODUCER AND PROBIOTIC, International Union of Microbiological Societies 2011 Congress, 2011.09. |
| 40. |
Said E Desouky, Yasuhiro Igarashi, Paul Williams,
Kenji Sonomoto, Jiro Nakayama, SCREENING OF ANTIPATHOGENIC AGENTS TARGETING
CYCLIC PEPTIDES-MEDIATED QUORUM SENSING OF
GRAM-POSITIVE BACTERIA, International Union of Microbiological Societies 2011 Congress, 2011.09. |
| 41. |
Mohammad R Islam, Mami Nishie, Akira Takano,
Jun-Ichi Nagao, Kouki Shioya, Takeshi Zendo,
Jiro Nakayama, Daisuke Kohda, Kenji Sonomoto, RING A OF NUKACIN ISK-1: A LIPID II BINDING MOTIF, International Union of Microbiological Societies 2011 Congress, 2011.09. |
| 42. |
Tijo Varghese Puramattathu, Mohammad R. Islam,
Mami Nishie, Sae Yanagihara, Jun-Ichi Nagao,
Ken-Ichi Okuda, Takeshi Zendo, Jiro Nakayama,
Kenji Sonomoto, ENHANCED NUKACIN D13E PRODUCTION IN
LACTOCOCCUS LACTIS NZ9000 BY THE ADDITIONAL
EXPRESSION OF IMMUNITY GENES, International Union of Microbiological Societies 2011 Congress, 2011.09. |
| 43. |
Rodney H Perez, Naoki Ishibashi, Kohei Himeno, Takeshi Zendo, Jiro Nakayama,
Kenji Sonomoto, INVESTIGATION OF THE REGULATION MECHANISM OF MULTIPLE BACTERIOCIN
PRODUCTION IN ENTEROCOCCUS FAECIUM NKR-5-3 USING A DEVELOPED ESI-LC/MS
SYSTEM, International Union of Microbiological Societies 2011 Congress, 2011.09. |
| 44. |
J. Nakayama , N. Sakamoto ,K. Kato , K. Sonomoto, 16S rRNA pyrosequencing-based investigation of the lactobacilli community in nukadoko, a fermented rice bran used for Japanese pickles, 10th symposium on lactic acid bacteria, 2011.08. |
| 45. |
Ryoji Yokohata, Mami Sato,Kenzo Nishiguchi, Kenji Sonomoto, Jiro Nakayama, Antagonist design of gelatinase biosynthesis-activating pheromone of Enterococcus faecalis based on reverse alanine scanning, 5th International Peptide Symposium, 2010.12. |
| 46. |
Jiro Nakayama, Kenji Sonomoto, Development of inhibitors targeting fsr quorum sensing system of Enterococcus faecalis, 3rd ASM Conference on Enterococci, 2010.08. |
| 47. |
Jiro Nakayama, Takako Kobayashi, Kenji Sonomoto, Aberrancy in faecal bacterial community structures of allergic infants profiled by 16S rRNA pyrosequencing, International scientific conference probiotics and prebiotics, 2010.06. |
| 48. |
Jiro Nakayama, Impact of oral administration of probiotics, Bifidobacterium breve M-16V, in early infancy on the development of gastro-intestinal microbiota, 2nd TNO beneficial micorobes confernce, 2010.03. |
| 49. |
Status of Recent Research in Probiotic used as an additive to livestock. Annual meeting of The Japanese Society for Bioscience, Biotechnology and Agro-Chemistry. |
| 50. |
Nakayama, J., Peptide-mediated cell-cell communication in Gram-positive bacteria, The XVth international symposium on gnotobiology, 2005.07. |
| 51. |
Functional analysis of FsrB involved in biosynthesis of cyclic peptide quormone,GBAP, in Enterococcus faecalis. |
