Kyushu University Academic Staff Educational and Research Activities Database
List of Presentations
Shigeki Sasaki Last modified date:2017.10.09

Professor / Department of Chemo-Pharmaceutical Sciences / Department of Chemo-Pharmaceutical Sciences / Faculty of Pharmaceutical Sciences


Presentations
1. Hidenori Okamura, Yosuke Taniguchi, Shigeki Sasaki, THE PSEUDO-CYTIDINE DERIVATIVE ENABLES THE FORMATION OF TRIPLEX DNA WITH MULTIPLE CG INVERSION SITES TO INHIBIT TRANSCRIPTION, 12th France-Japan Drug Delivery Systems Symposium, 2016.10.10.
2. 大城郁也, 實崎大地, 松本卓也, 谷口 陽祐, 佐々木 茂貴, 「Pinpoint modification of 6-NH2 of the adenine in RNA by the functionality transfer oligonucleotides and its impact on reverse-transcription and translation, ISNAC2016 第43回国際核酸化学シンポジウム, 2016.09.27.
3. Kenji Kikuta, Yosuke Taniguchi, Shigeki Sasaki, Oligonucleotides incorporating the 4-vinylpyrimidine derivatives to investigate the cross-link formation with mRNA, ISNAC2016 第43回国際核酸化学シンポジウム, 2016.09.27.
4. Hidenori Okamura, Lei Wang, Yosuke Taniguchi, Shigeki Sasaki, Antigene effect of triplex forming oligonucleotide incorporating the new Y-dC derivative for the selective recognition of CG basepairs in the anti-parallel triplex DNA, ISNAC2016 第43回国際核酸化学シンポジウム, 2016.09.27.
5. Mei Miyazaki, Yosuke Taniguchi, Nozomu Matsueda, Shigeki Sasaki, Synthesis of the N2-substituted 2'-deoxyguanosine derivatives and the binding evaluation for the triplex DNA formation, ISNAC2016 第43回国際核酸化学シンポジウム, 2016.09.27.
6. Hayate Takasaki, Yurie Hatano, Yosuke Taniguchi, Shigeki Sasaki, Design of the reactive nucleoside analogs and its incorporation into the oligonucleotised for the site-selective chemicalmodification of the 2'-hydroxyl group of RNA, ISNAC2016 第43回国際核酸化学シンポジウム, 2016.09.27.
7. Yosuke Taniguchi, Yizhen Yin, Shigeki Sasaki, Synthesis and properties of 8-halo-7-deazadGTP analogues for binding to the 8-oxodGTP repair enzymes, ISNAC2016 第43回国際核酸化学シンポジウム, 2016.09.27.
8. Yukiko Abe, Shigeki Sasaki, DNA cleavage at the AP site by nucleobase-polyamine conjugates, ISNAC2016 第43回国際核酸化学シンポジウム, 2016.09.27.
9. 谷口 陽祐, Yizhen Yin, 佐々木 茂貴, Design and Development of oxidation nucleoside analogs for the inhibition of their repair enzymes, XXIIInternational Roundtable on Nucleosides Nucleotides and Nucleic Acids, 2016.07.19.
10. 佐々木 茂貴, 實崎大地, 大城郁也, 鬼塚和光, 西本篤志, 谷口 陽祐, The Functionality Transfer Oligonucleotides for Site-Selective Modification of Cytidine or Adenine, XXIIInternational Roundtable on Nucleosides Nucleotides and Nucleic Acids, 2016.07.19.
11. Hidenori Okamura, Yosuke Taniguchi, Shigeki Sasaki, Synthesis of novel pseudocytidine derivatives for the selective recognition of CG base pairs in triple-helix DNA, PACIFICHEM2015, 2015.12.19.
12. Fuchi Yasufumi, Shigeki Sasaki, Efficient covalent capture of 8-nitroguanosine via a multiple hydrogenbonded complex, PACIFICHEM2015, 2015.12.19.
13. Kensuke Kawara, Shigeki Sasaki, Dynamic and mutual chiral induction system between B-, Z-DNA and the chiral[5]helicene-spermine ligand, PACIFICHEM2015, 2015.12.19.
14. Hirotaka Murase, Shigeki Sasaki, Selective and cooperative binding of small molecular ligands to a GC repetitive site of DNA mediated by multiple complexationwith metal cations, PACIFICHEM2015, 2015.12.19.
15. Yosuke Taniguchi, Yoshiya Kikukawa, Shigeki Sasaki, Recognition and discrimination between 8-oxo-2'deoxyguanosin and 2'deoxyguanosine in DNA using the adenosine-1,3-diazaphenoxazine nucleoside derivatives, PACIFICHEM2015, 2015.12.19.
16. 佐々木 茂貴, Design of non-natural nucleosides for the formation of stable triplexes toward the duplex DNA having CG or TA interrupting sites, Asian Three Round Table Meeting on Nucleic Acids 2015 (A3RONA), 2015.09.19.
17. 佐々木 茂貴, DNA-to-RNA Inter-strand functionality-transfer reaction for the site-specific modification of RNA, The 5th New Phase International Conference on Cutting-Edge Organic Chemistry in Asia
(NICCEOCA-5), 2014.12.02.
18. 佐々木 茂貴, Site-Specific Chemical Modification of RNA and Impact on RNA Function
, Asian Three Round Table Meeting on Nucleic Acids 2014 (A3RONA), 2014.10.18.
19. 佐々木 茂貴, Molecular Design for Targeting DNA and RNA
, The 2nd Paul A. Grieco Symposium, 2014.10.07.
20. Yosuke Taniguchi, Okamura Hidenori, Shigeki Sasaki, Development of triplex-forming oligonucleotide having artificial nucleoside analogues to inhibit the gene expression as an antigene strategy, DPhG Annual Meeting 2014 , 2014.09.25.
21. Shigeki Sasaki, Daichi Jitsuzaki, Kazumitsu Onizuka, Atsushi Nishimoto, Ikuya Oshiro, Yosuke Taniguchi, Nickel complex catalyse the inter-strand functionality transter reaction for the site-selective modification of RNA, The 24th French-Japanses Symposium on Medicinal and Fine Chemistry, 2014.09.15.
22. Hidenori Okamura, Yosuke Taniguchi, Shigeki Sasaki, SELECTIVE CG BASE PAIR RECOGNITION BY PYRIMIDINE NUCLEOSIDE ANALOGUES IN ALL FOUR FLANKING BASE PAIRS WITHIN ANTIPARALLEL TRIPLE HELIX DNA, "IS3NA A. Holy IRT Poster Awards" (XXI Round Table on Nucleosides, Nucleotides and Nucleic Acids), 2014.08.25.
23. Yosuke Taniguchi, Yoshiya Kikukawa, Keitaro Fukabori, Yohei Koga, Shigeki Sasaki, DETECTION OF 8-OXO-2'-DEOXYGUANOSINE IN DNA USING THE PROBE CONTAINING ADENOSINE-1,3-DIAZAPHENOXADINE-4-ON DERIVATIVES, "IS3NA A. Holy IRT Poster Awards" (XXI Round Table on Nucleosides, Nucleotides and Nucleic Acids), 2014.08.25.
24. Shigeki Sasaki, Recognition molecules for 8-oxo-, 8-nitro-and 8-haloguanosine, UK-Japan collaborative symposium on Nucleic Acids, 2014.07.03.
25. Shigeki Sasaki, A New Therapeutic Approach Based on Genome-Targeting Chemistry, The 11th International Symposium, Futures in Drug Discovery and Development, 2014.01.17.
26. Shigeki Sasaki, Daichi Jitsuzaki, Onizuka Kazumitsu, Nishimoto Atsushi, Shibata Atsushi, Oshiro Ikuya, Yosuke Taniguchi, An Efficient Reaction for Pinpoint Modification of RNA Promoted by Proximity Effect via Transition Metal Complex, ICCEPOCA-8/NICCEOCA-4, 2013.11.27.
27. Hedenori Okamura, Yosuke Taniguchi, Shigeki Sasaki, N²-Modified Isocytidine Derivatives for Selective CG Base Pair Recognition in the Triplex DNA, 3rd ACP Junior Symposium, 2013.11.24.
28. Hironori Koda, John BRAZIER, Shigeki Sasaki, Synthesis and evaluation of novel Hoechst derivatives for cooperative binding to repeating DNA sequences, The 40th International Symposium on Nucleic Acids Chemistry 2013, 2013.11.14.
29. Yosuke Taniguchi, Shigeki Sasaki, An antiproliferative ellect by targeting oncogene with antigene oligonucleotides containing WNA-βT in an anti-parallel triplex formation
, The 40th International Symposium on Nucleic Acids Chemistry 2013, 2013.11.13.
30. Ikuya Oshiro, Daichi Jitsuzaki, Atsushi Nishimoto, Kazumitsu Onizuka, Yosuke Taniguchi, Shigeki Sasaki, Sequence specific adenine modification of RNA by functionality-transfer ODN accelerated by metal cations, The 40th International Symposium on Nucleic Acids Chemistry 2013, 2013.11.13.
31. Jan Barta, Daichi Jitsuzaki, Yosuke Taniguchi, Shigeki Sasaki, ODN containing functionalized thioguanosine:Useful tools for selective guanosine RNA targeting, The 40th International Symposium on Nucleic Acids Chemistry 2013, 2013.11.13.
32. Yosuke Taniguchi, Akira Tomizaki, Hidenori Okamura, Shohei Misumi, Tomoko Takaki, Naoto Ishibashi, Shigeki Sasaki, Synthesis and Evaluation of Anti-parallel Triplex Formation of 1'-Pheny1-2'-Thymine Nucleoside Analogues for the Application to the Antigene Strategy, 9th AFMC International Medicinal Chemistry Symposium, 2013.10.17.
33. Shigeki Sasaki, Nishimoto A., Jitsuzaki D., Onizuka K., Yosuke Taniguchi, Nahatsugi F., T-Viny1 Derivative as an 4 Efficient and Selective Cross-Linking Agent for RNA and duplex DNA, 9th Annual Meeting of the OLIGONYCLEOTIDE Therapeutics Society, 2013.10.07.
34. Shigeki Sasaki, Site-Specific Chemical Modification of RNA and Impact on its Function, Asia 3 Roundtable of Nucleic Acids 2013, Japan, 2013.08.31.
35. Shigeki Sasaki, Yosuke Taniguchi, D. Jitsuzaki, K.Onizuka, A.Nishimoto, I.Oshiro, A.Shibata, Functionality Transfer for the Pinpoint Selective Modefication of RNA Inducible Reactivity Mediated by Chelate Formation with Metal Cation, The 5th Asian Aeden Confernce, 2013.08.05.
36. Yosuke Taniguchi, Shigeki Sasaki, Inhibition of the Cell Proliferation Using Triplex Forming Oligonucleotides Containing a W-shaped Nucleoside Analogues(WNA-βT)」, ACMS 2013, 2013.07.18.
37. Hidenori Okamura, Yosuke Taniguchi, Shigeki Sasaki, N-(Guanidinoethyl)-2'-deoxy-5-methylisocytidine exhibits selective recognithion of the CG inversion site for the formation of anti-parallel triplex DNA, ACMS 2013, 2013.07.18.
38. Shigeki Sasaki, Daichi Jitsuzaki, Atsushi Nishimoto, Kazumitsu Onizuka, Fumi Nagatsugi, Yosuke Taniguchi, An efficient method for RNA modification with high sequence and base selectivity using non-natural efficient method for RNA modification with high sequence and base selectivity using non-natural functional ODN, Gordon Research Confernces, 2013.06.30.
39. Shigeki Sasaki, Molecular design and synthesis for selective recognition and reaction of DNA and RNA, Report of Lectureship in Hong Kong, 2013.04.16.
40. Shigeki Sasaki, Genome-targeting chemistry for a new therapeutic approach, Frontiers in Medicinal Chemistry, 2013.03.20.
41. Shigeki Sasaki , Molecular design of non-natural nucleosides for selective recognition and reaction with DNA and RNA
, 13th Tetrahefron Symposium (ASIA EDITION), 2012.11.29.
42. Shigeki Sasaki, Non-natural nucleoside analogs for the formation of the stable triplex DNA and its application to inhibition of gene expression, 10th France-Japan DDS Symposium, 2012.10.11.
43. Shigeki Sasaki, Intelligent oligonucleotides for modification and detection of genes, The 1st International Symposium on Polymer Ecomaterials (PEM2012), 2012.08.20.
44. Shigeki Sasaki, Yosuke Taniguchi, Ryota Kawaguchi, Adenosine-1,3-diazaphenoxazine Derivative (Adap) as a Selective Fluorescent Probe for 8-Oxo-2'-deoxyguanosine in DNA, JSPS A3 foresight program, 10th seminar on Guilin, 2011.05.
45. Shigeki Sasaki, Current Status of Oligonucleotide Chemistry and Application, The 4th Pharmaceutical Sciences World Congress 2010, 2010.11.16.
46. Shigeki Sasaki, Yosuke Taniguchi, Kazumitsu Onizuka, Functionality Transfer Reaction (FTR)as a Powerful Tool for Site-Specific Modification of RNA, ICCEOCA-5/NICCEOCA-1, 2010.11.08.
47. Shigeki Sasaki, Yosuke Taniguchi, Kazumitsu Onizuka, New Biological Tool for Site-Specific Modification of RNA by Utilizing Functionality Transfer Reaction , 9th China-Japan-Korea Foresight Joint Symposium, 2010.06.21.
48. Development of novel bisaryl derivate inducing B-Z transition.
49. Dicopper ligand conjugated DNA probe for detecting of nucleic acids.
50. Development of functionality transfer nucleic acids with the sbility to site-specifically modify RNA.
51. Strand invasion by oligonucleotide incorporating the WNA analongue.
52. Development of Selective Cross-Linking agents to RNA Cytosine.
53. Development of Novel Ligands for the Recognition of Z-DNA.
54. Development of the functional probe that amplify signals in organic chemistry.
55. Effects of the WNA derivatives containing a five-membered heterocycle on the triplex formation.
56. Development of DNA structure recognition molecules by association of ligands along a DNA template.
57. Development of molecules for the recognition of DNA with long repeated.
58. Synthesis and properties of novel 8-oxoG-clamp derives.