Kyushu University Academic Staff Educational and Research Activities Database
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Kiichiro Teruya Last modified date:2019.06.13

Assistant Professor / Systems Bioengineering
Department of Bioscience and Biotechnology
Faculty of Agriculture


Graduate School
Undergraduate School


Academic Degree
Ph.D.
Field of Specialization
Cellular Regulation Technology
Outline Activities
Activity on study:
Development of functional foods for anti-virus, anti-stress, anti-allergy, immunopotentiation, anti-oxidation, anti-life style-related diseases; Development of establishment of recombinant protein high productive animal cells by activation of promoter;
Development of serum-free and non-protein high density cell culture method; Production and functional improvement of antigen-specific human monoclonal antibody using in vitro immunization method.
Research
Research Interests
  • Investigation of the factors for anti-aging and anti-oxidative stress related decease, and application to engineering of clinical food functions

    keyword : functional foods, cultured animal cells, life style-related diseases.
    1997.05Development of functional foods for anti-virus, anti-stress, anti-allergy, immunopotentiation, anti-oxidation, anti-life style-related diseases..
  • Development of functional foods for anti-life style-related diseases.
    keyword : functional foods, cultured animal cells, life style-related diseases.
    1997.05Development of functional foods for anti-virus, anti-stress, anti-allergy, immunopotentiation, anti-oxidation, anti-life style-related diseases..
  • Evaluations of functional foods for anti-virus, anti-stress, anti-allergy, immunopotentiation, anti-oxidation, anti-life style-related diseases.
    keyword : functional foods, cultured animal cells, life style-related diseases.
    1997.05Development of functional foods for anti-virus, anti-stress, anti-allergy, immunopotentiation, anti-oxidation, anti-life style-related diseases..
Current and Past Project
  • The Research Institute for Biology and Food in Fukuoka Industrial Technology Center invented a new method for production of hydroxyapatite sheet which exhibits high-affinity for adhesive animal cells. Kyushu University and Astec Co. Ltd collaborated with the institute to develop a novel 3 dimension high density cell culture system for large-scale production of recombinant proteins.
Academic Activities
Papers
1. Kiichiro Teruya, Yuki Myojin-Maekawa, Fumio Shimamoto, Hiromitsu Watanabe, Noboru Nakamichi, Koichiro Tokumaru, Sennosuke Tokumaru, Sanetaka Shirahata, Protective effects of the fermented milk Kefir on X-ray irradiation-induced intestinal damage in B6C3F1 mice., Biological and Pharmaceutical Bulletin, 10.1248/bpb.b12-00709, 36, 3, 352-359, 2013.03.
2. Zhongyuan Zhang, Kiichiro Teruya, Hiroshi Eto, Sanetaka Shirahata, Induction of Apoptosis by Low-Molecular-Weight Fucoidan through Calcium- and Caspase-Dependent Mitochondrial Pathways in MDA-MB-231 Breast Cancer Cells, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 10.1271/bbb.120631, 77, 2, 235-242, 2013.02.
3. Zhongyuan Zhang, Kiichiro Teruya, Toshihiro Yoshida, Hiroshi Eto, Sanetaka Shirahata, Fucoidan extract enhances the anti-cancer activity of chemotherapeutic agents in MDA-MB-231 and MCF-7 breast cancer cells, Marine Drugs, 10.3390/md11010081, 9, 11, 81-98, 2013.01.
4. Zhongyuan Zhang, Kiichiro Teruya, Hiroshi Eto, Sanetaka Shirahata, Fucoidan extract induces apoptosis in MCF-7 cells via a mechanism involving the ros-dependent JNK activation and mitochondria-mediated pathways., PLoS One., 6, 11, e27441, 2011.11.
5. Kiichiro Teruya, Yoshihito Daimon, Xiao-Yan Dong, Yoshinori Katakura, Takumi Miura, Akira Ichikawa, Tsukasa Fujiki, Makiko Yamashita, Tetsuya Mori, Hideya Ohashi, Sanetaka Shirahata, An Approach to Further Enhance the Cellular Productivity of Exogenous Protein Hyper-producing Chinese Hamster Ovary (CHO) Cells, Cytotechnology, 10.1007/s10616-005-3765-4, 47, 1-3, 29-36, 47, 29-36, 2005.01.
6. Ryuhei Nishikawa, Kiichiro Teruya, Yoshinori Katakura, Kazuhiro Osada, Takeki Hamasaki, Taichi Kashiwagi, Takaaki Komatsu, Yuping Li, Jun& Ye, Akira Ichikawa, Kazumichi Otsubo, Shinkatsu Morisawa, Qianghua Xu, Sanetaka Shirahata, Electrolyzed Reduced Water Supplemented with Platinum Nanoparticles Suppresses Promotion of Two-stage Cell Transformation, Cytotechnology, 10.1007/s10616-005-3759-2, 47, 1-3, 97-105, 47, 97-105, 2005.01.
7. Jun Ye, Yuping Li, Kiichiro Teruya, Yoshinori Katakura, Akira Ichikawa, Hiroshi Eto, Mutsutaka Hosoi, Masako Hosoi, Shinji Nishimoto, Sanetaka Shirahata, Enzyme-digested Fucoidan Extracts Derived from Seaweed Mozuku of Cladosiphon novae-caledoniaekylin Inhibit Invasion and Angiogenesis of Tumor Cells, Cytotechnology, 10.1007/s10616-005-3761-8, 47, 1-3, 117-126, 47, 117-126, 2005.01.
Presentations
1. Yoshihiro Kusumoto, Shingo Kajisa, Hiroshi Eto, Toshihiro Yoshida, Sanetaka Shirahata, Kiichiro Teruya, Combined Use of Enzymatically Digested Low-Molecular Weight Fucoidan Extract and Anti-Cancer Drugs Enhances Their Anti-Cancer Effects., The 29th Annual and International Meeting of the Japanese Association for Animal Cell Technology, 2016.11.
2. Yuko Ishibashi, Kiichiro Teruya, Hiroshi Eto, Sanetaka Shirahata, Enzymatically digested low-molecular weight fucoidan suppresses the growth of cancer cells., The 27th Annual and International Meeting of the Japanese Association for Animal Cell Technology, 2014.11.
3. Ririko Goto, Kiichiro Teruya, Hiroshi Eto, Toshihiro Yoshida, Sanetaka Shirahata, Combined use of enzymatically digested low-molecular weight fucoidan extract and an anti-cancer drug enhance their anti-tumor effects., The 27th Annual and International Meeting of the Japanese Association for Animal Cell Technology, 2014.11.
4. Kiichiro Teruya, Sanetaka Shirahata, Cancer Cell-Specific Apoptosis Induction and Alteration of Cell Surface Sugar Chain Structures by Low Molecular Weight Fucoidan Extract.
, The 27th Annual and International Meeting of the Japanese Association for Animal Cell Technology, 2014.11.
5. Kiichiro Teruya, Takeki Hamasaki, Zhongyuan Zhang, Hiroshi Eto, Sanetaka Shirahata, Cancer Cell-specific Apoptosis Induction and Alteration of Cell Surface Sugar Chain Structures by Low Molecular Weight Fucoidan Extract., IUFoST 2014, 17th World Congress of Food Science and Technology, 2014.08.
Membership in Academic Society
  • Japan Society for Bioscience, Biotechnology, and Agrochemistry
  • Japanese Association for Animal Cell Technology
  • Molecular Biology Society of Japan
  • Japanese Society for Immunology
  • The Japanese Tissue Culture Association
  • Japanese Society of Nutrition and Food Science
  • Japanese Association for Food Immunology
  • Japanese Cancer Association
  • The Japanese Biochemical Society
  • Japanese Society for Medical Use of Functional Foods
  • The Society for Biotechnology, Japan
  • The Japanese Society for Functional Water
Educational
Educational Activities
[Graduate School]
Seminar of Cellular Regulation Technology (1997-2010)
Advanced in Systems Biological Chemistry (2010-)
Project research in Systems Biology (2010-)
Advanced in Cellular Function Technology (2016-)
Basic Cellular Regulation Technology (2016)

[Undergraduate School ]
Basic Biology (2008-2014)
Molecular Cell Biology (2015-)
Laboratory Course of Analytical Chemistry (2009-2017)
Laboratory Work of Basic Microbiology (2012-)
Laboratory Work of Food Chemistry (2012-2017)
Laboratory Work of Physical Chemistry (2018-)
Physical Chemistry (2014-)
G30 Food Science (2015-)

[Common University's education]
Core Seminar (2008)
Natural Science Experiments (2015-2016, 2018)