Kyushu University Academic Staff Educational and Research Activities Database
List of Reports
MAMI NODA Last modified date:2019.06.21

Associate Professor / Laboratory of Pathophysiology / Department of Pharmaceutical Health Care and Sciences / Faculty of Pharmaceutical Sciences

1. Morita M, Ikeshima-Kataoka H, Kreft M, Vardjan N, Zorec R, Noda M., Metabolic Plasticity of Astrocytes and Aging of the Brain., Int J Mol Sci., doi: 10.3390/ijms20040941, 2019.02.
2. Noda M, Ifuku M, Hossain MS, and Katafuchi T., Glial Activation and Expression of the Serotonin Transporter in Chronic Fatigue Syndrome., Front Psychiatry 2018, Nov 16;9:589. , doi: 10.3389/fpsyt.2018.00589, 2018.11.
3. Caterina Scuderi, Mami Noda & Alexei Verkhratsky, Neuroglia: Molecular Mechanisms in Psychiatric Disorders., doi: 10.3389/fnmol.2018.00407, 2018.10.
4. Osipova ED, Semyachkina-Glushkovskaya OV, Morgun AV, Pisareva NV, Malinovskaya NA, Boitsova EB, Pozhilenkova EA, Belova OA, Salmin VV, Taranushenko TE, Noda M, Salmina AB. , Gliotransmitters and cytokines in the control of blood-brain barrier permeability., Rev Neurosci., 10.1515/revneuro-2017-0092, pii: /j/revneuro.ahead-of-print/revneuro-2017-0092/revneuro-2017-0092.xml, 2018.01.
5. Mami Noda, Microglia and its phagocytic abilities. 23(1): 11-18 (2017), Clinical Pathophysiology, 23(1): 11-18, 2017.06.
6. Mami Noda, Mechanisms of nicotine-induced neuroprotection: Inhibition of NADPH oxidase and subsequent proton channel activation by stimulating alpha 7 nicotinic acetylcholine receptor in activated microglia., Advances in Neuroimmune Biology, 10.3233/NIB-160119, 6 (2015/2016) 107–115, 2016.06.
7. MAMI NODA, Dysfunction of glutamate receptors in microglia may cause neurodegeneration. , Curr Alzheimer Res. , 2015.10.
8. MAMI NODA, Possible role of glial cells in the relationship between thyroid dysfunction and mental disorders. , Front. Cell. Neurosci. 9:194, 2015.06.
9. MAMI NODA, Kyota Fujita, Ikuroh Ohsawa, Masafumi Ito, Kinji Ohno, Multiple Effects of Molecular Hydrogen and its Distinct Mechanism. , Journal of Neurolog Disorders , 2:6, 2014.12, [URL].
10. MAMI NODA, Ikuroh Ohsawa, Masafumi Ito, Kinji Ohno, Beneficial effects of hydrogen in the CNS and a new brain-stomach interaction., European Journal of Neurodegenerative Diseases , 3(1): 25-34 , 2014.12.
11. Zeidán-Chuliá F, Salmina AB, Malinovskaya NA, MAMI NODA, Verkhratsky A, Fonseca Moreira JC, The glial perspective of autism spectrum disorders., Neuroscience & Biobehavioral Reviews, 2014 Jan;38:160-72. doi: 10.1016/j.neubiorev.2013.11.008. , Zeidán-Chuliá F, Salmina AB, Malinovskaya NA, Noda M, Verkhratsky A & Fonseca Moreira JC., 2014.01.
12. MAMI NODA, Beppu K, Possible Contribution of Microglial Glutamate Receptors to Inflammatory Response upon Neurodegenerative Diseases., J Neurol Disord 1: 131. doi:10.4172/2329-6895.1000131 , 2013.11.
13. MAMI NODA, 井福 正隆, Mori Y, Verkhratsky A, Calcium Influx Through Reversed NCX Controls Migration of Microglia., Adv Exp Med Biol. , Noda M, Ifuku M, Mori Y, Verkhratsky A. , 2013.03, Microglia, the immune cells of the central nervous system (CNS), are busy and vigilant guards of the adult brain, which scan brain parenchyma for damage and activate in response to lesions. Release of danger signals/chemoattractants at the site of damage initiates microglial activation and stimulates migration. The main candidate for a chemoattractant sensed by microglia is adenosine triphosphate (ATP); however, many other substances can have similar effects. Some neuropeptides such as angiotensin II, bradykinin, endothelin, galanin and neurotensin are also chemoattractants for microglia. Among them, bradykinin increases microglial migration using mechanism distinct from that of ATP. Bradykinin-induced migration is controlled by a G(i/o)-protein-independent pathway, while ATP-induced migration involves G(i/o) proteins as well as mitogen-activated protein kinase (MAPK)/extracellular signal-regulated kinase (ERK)-dependent pathway. Galanin was reported to share certain signalling cascades with bradykinin; however, this overlap is only partial. Bradykinin, for example, stimulates Ca(2+) influx through the reversed Na(+)/Ca(2+) exchange (NCX), whereas galanin induces intracellular Ca(2+) mobilization by inositol-3,4,5-trisphosphate (InsP(3))-dependent Ca(2+) release from the intracellular store. These differences in signal cascades indicate that different chemoattractants such as ATP, bradykinin and galanin control distinct microglial functions in pathological conditions such as lesion and inflammation and NCX contributes to a special case of microglial migration..
14. Verkhratsky A, MAMI NODA, Parpura V, Kirischuk S, Sodium fluxes and astroglial function. , Adv Exp Med Biol., 2013.03, Astrocytes exhibit their excitability based on variations in cytosolic Ca(2+) levels, which leads to variety of signalling events. Only recently, however, intracellular fluctuations of more abundant cation Na(+) are brought in the limelight of glial signalling. Indeed, astrocytes possess several plasmalemmal molecular entities that allow rapid transport of Na(+) across the plasma membrane: (1) ionotropic receptors, (2) canonical transient receptor potential cation channels, (3) neurotransmitter transporters and (4) sodium-calcium exchanger. Concerted action of these molecules in controlling cytosolic Na(+) may complement Ca(2+) signalling to provide basis for complex bidirectional astrocyte-neurone communication at the tripartite synapse..
15. Therapeutic approach to neurodegenerative diseases by medical gases: focusing of redox signaling and related antioxidant enzymes. .
16. Noda M, Ifuku M, Okuno Y, Beppu K, Mori Y, Naoe S., Neuropeptides as Attractants of Immune Cells in the Brain and their Distinct Signaling.
, Advances in Neuroimmune Biology, 2011.07.
17. Noda M, Fujita K, Chih-Hung Lee CH, Yoshioka T., The principle and the potential approach to ROS-dependent cytotoxicity by non-pharmaceutical
therapies: Optimal use of medical gases with antioxidant properties.
, Curr Pharm Design, 2011.07.
18. Fujita K, Nakabeppu Y, Noda M., Therapeutic effects of hydrogen in animal models of Parkinson’s disease. , Animal Model of Parkinson’s Disease, 2011.05.
19. Kettenmann H, Hanisch UW, Noda M, Verkhratsky A., Physiology of microglia, Physiol Rev., 2011.04.
20. Fares Zeidán-Chuliáa and Mami Noda, Opening The Mesenchymal Stem Cell Tool Box. , European Journal of Dentistry , 2009.07.
21. Noda M, Sasaki K, Ifuku M, Wada K, Multifunctional effects of bradykinin on glial cells in relation to potential anti-inflammatory effects. , Neurochem. Int. , doi:10.1016/j.neuint.2007.06017. , 2007.09.
22. Noda M., Kettenmann H., Wada K., Anti-inflammatory effects of kinins via microglia in the central nervous system., Biol. Chem., 387: 167-171, 2006.01.
23. Noda M., Higashida H., Aoki S., Wada K., Multiple signal transduction pathways mediated by 5-HT receptors., Molecular Neurobiology, 29: 31-39, 2004, 2004.01.
24. Noda M., Kariura Y., Amano T., Manago Y., Nishikawa K, Aoki S. and Wada K., Expression and Function of Kinin Receptors in Microglia., 45: 437-442, 2004.01.