Kyushu University Academic Staff Educational and Research Activities Database
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Hideki Sumimoto Last modified date:2017.08.03

Professor / Bioregulation Biochemistry
Department of Basic Medicine
Faculty of Medical Sciences

Graduate School
Administration Post
Dean of the School of Medicine

Academic Degree
a doctor of medicine
Field of Specialization
Research Interests
  • (1) Mechanism underlying activation of the reactive oxygen-producing NADPH oxidases
    (2) Molecular mechanisms for the determination of cell polarity, cell shape, cell growth, and cell differentiation
    keyword : signal transduction, Protein domain , NADPH oxidase, reactive oxygen species
Academic Activities
1. Sumimoto, H. , Structure, regulation, and evolution of Nox-family NADPH oxidases that produce reactive oxygen species., FEBS J. 275, 3249–3277.2008, 2008.05.
1. Taura M, Miyano K, Minakami R, Kamakura S, Takeya R, Sumimoto H., A region N-terminal to the tandem SH3 domain of p47phox plays a crucial role in the activation of the phagocyte NADPH oxidase., Biochem J. 419(2):329- 338, 2009., Biochem J. 419(2):329- 338, 2009., 2009.04.
2. Maehara Y, Miyano K, Sumimoto H. , Role for the first SH3 domain of p67phox in activation of superoxide-producing NADPH oxidases., Biochem Biophys Res Commun. 379, 589–593., Biochem Biophys Res Commun. 379, 589–593., 2009.02.
3. Shono, T., Yokoyama, N., Uesaka, T., Kuroda, J., Takeya, R., Yamasaki, T., Amano, T., Mizoguchi, M., Suzuki, S. O., Niiro, H., Miyamoto, K., Akashi, K., Iwaki, T., Sumimoto, H., and Sasaki, T. , Enhanced expression of NAPDH oxidase Nox4 in human gliomas and its roles in cell proliferation and survival. , Int. J. Cancer.123, 787–792, 2008., 2008.08.