Kyushu University Academic Staff Educational and Research Activities Database
List of Papers
Dongchon Kang Last modified date:2016.10.19

Professor / Pathobiology / Department of Basic Medicine / Faculty of Medical Sciences


Papers
1. Wang, L., Ishihara, T., Ibayashi, Y., Tatsushima, K., Daiki Setoyama, Hanada, Y., Takeichi, Y., Sakamoto, S., Yokota, S., Mihara, K., Dongchon Kang, Ishihara, N., Takayanagi, R, Nomura, M., Disruption of mitochondrial fission in the liver protects mice from diet-induced obesity and metabolic deterioration, Diabetologia, 58, 2015.08.
2. Ichihara, K., Yomamoto, Y., Hotta, T., Ishibashi, M., Dongchon Kang, Collaborative derivation of reference intervals for major clinical laboratory tests in Japan, 53, 2015.09.
3. Ikeda, M., Ide, T., Fujino, T., Arai, S., Saku, K., Kakino, T., Tyynismaa, H., Yamasaki, T., Yamada, K., Dongchon Kang, Suomalainen, A, Sunagawa, K., Overexpression of TFAM or Twinkle Increases mtDNA Copy Number and Facilitates Cardioprotection Associated with Limited Mitochondrial Oxidative Stress, 10, 3, 2015.02.
4. Ikeda, K, Ichihara, K., Hashiguchi, T., Hidaka, Y., Dongchon Kang, Maekawa, M, Matsumoto, H., Matsushita, K., Okubo, S., Tsuchiya, T., Furuta, K., Jslm,, Evaluation of the Short-Term Stability of Specimens for Clinical Laboratory Testing, 13, 2, 2015.04.
5. Yuko Hirota, Yamashita, S, Kurihara, Y, Jin, XL, Aihara, M, Saigusa, T, Dongchon Kang, Kanki, T, Mitophagy is primarily due to alternative autophagy and requires the MAPK1 and MAPK14 signaling pathways, 11, 2, 2015.02.
6. Unal, S., Gumruk, F., Yigit, S., Tuncer, M., Tavil, B., Cil, O., Takci, S, Urata, M., Hotta, T., Dongchon Kang, Cetin, M., A novel mutation in protein C gene (PROC) causing severe phenotype in neonatal period, 61, 4, 2014.01.
7. Mukai, N., Yasuda, M., Ninomiya, T., Hata, J., Hirakawa, Y., Ikeda, F., Fukuhara, M., Hotta, T., Koga, M., Nakamura, U., Dongchon Kang, Kitazono, T., Kiyohara, Y., Thresholds of various glycemic measures for diagnosing diabetes based on prevalence of retinopathy in community-dwelling Japanese subjects: the Hisayama Study, 13, 1, 2014.04.
8. Iizuka, Y., Yamashita, K., Sakasegawa, S. I., Hanada, T., Tani, W., Adachi, H., Haga, R, Yamaguchi, M., Kurotani, W, Sekiguchi, M., Osawa, S., Dongchon Kang, Ueda, S., Improvement and evaluation of a 1,2-dioleoylglycerol method for measuring pancreatic lipase catalytic activity in serum, 14, 3, 2014.04.
9. Hoshina, T., Nakashima, Y., Sato, D., Nanishi, E., Nishio, H., Nagata, H., Yamamura, K., Doi, T., Shiokawa, Y., Yamazaki, T., Koga, Y., Dongchon Kang, Ohga, S., Hara, T., Staphylococcal endocarditis as the first manifestation of heritable protein S deficiency in childhood, 14, 3, 2014.01.
10. Baba, T., Otake, H., Sato, T., Miyabayashi, K., Shishido, Y., Wang, C. Y., Shima, Y., Kimura, H., Yagi, M., Ishihara, Y., Hino, S., Ogawa, H., Nakao, M., Yamazaki, T., Dongchon Kang, Ohkawa, Y., Suyama, M., Chung, B. C., Ken-ichirou Morohashi, Glycolytic genes are targets of the nuclear receptor Ad4BP/SF-1, 14, 9, 2014.04.
11. Aihara, M., Jin, X., Kurihara, Y., Yoshida, Y., Yuichi Matsushima, Oku, M., Hirota, Y., Saigusa, T., Aoki, Y., Dongchon Kang, Kanki, T., The Tor and Sin3-Rpd3 complex regulate expression of the mitophagy receptor protein Atg32, 14, 9, 2014.05.
12. Kanki, T., Kurihara, Y, Jin, X, Goda, T., Ono, Y., Aihara, M., Hirota, Y., Saigusa, T., Aoki, Y., Takeshi Uchiumi, Dongchon Kang, Casein kinase 2 is essential for mitophagy, 14, 9, 7, 2013.07.
13. Fang, J., Takeshi Uchiumi, Mikako Yagi, Matsumoto, S., Amamoto, R., Takazaki, S., Haruyoshi Yamaza, Kazuaki Nonaka, Dongchon Kang, Dihydro-orotate dehydrogenase is physically associated with the respiratory complex and its loss leads to mitochondrial dysfunction, 33, 2, 1, 2013.01.
14. Matsuda, T., Kanki, T., Tanimura, T., Dongchon Kang, Matsuura, E. T., Effects of overexpression of mitochondrial transcription factor A on lifespan and oxidative stress response in Drosophila melanogaster, 430, 2, 5, 2013.01.
15. Uchiumi, T, Tanamachi, H, Kuchiwaki, K, Kajita, M, Matsumoto, S, Yagi, M, Kanki, T, Dongchon Kang, 「Mutation and functional analysis of ABCC2/multidrug resistance protein 2 in a Japanese patient with Dubin-Johnson syndrome」, 43, 6, 2013.03.
16. Ohga, S, Ishiguro, A, Takahashi, Y, Shima, M, Taki, M, Kaneko, M, Fukushima, K, Dongchon Kang, Hara, T, 「Protein C deficiency as the major cause of thrombophilias in childhood」, 55, 4, 2013.01.
17. Nakanishi, N, Fukuoh, A, Dongchon Kang, Iwai, S, Kuraoka, I, 「Effects of DNA lesions on the transcription reaction of mitochondrial RNA polymerase: implications for bypass RNA synthesis on oxidative DNA lesions」, 28, 6, 2013.01.
18. Dongchon Kang, [Mitochondrial stress in diseases], 85, 6, 2013.03.
19. Fang, J, Uchiumi, T, Yagi, M, Matsumoto, S, Amamoto, R, Saito, T, Takazaki, S, Kanki, T, Yamaza, H, Nonaka, K, Dongchon Kang, 「Protein instability and functional defects caused by mutations of dihydro-orotate dehydrogenase in Miller syndrome patients」, 32, 9, 2012.09.
20. Fujino, T, Ide, T, Yoshida, M, Onitsuka, K, Tanaka, A, Hata, Y, Nishida, M, Takehara, T, Kanemaru, T, Kitajima, N, Takazaki, S, Kurose, H, Dongchon Kang, Sunagawa, K, 「Recombinant mitochondrial transcription factor A protein inhibits nuclear factor of activated T cells signaling and attenuates pathological hypertrophy of cardiac myocytes」, 12, 9, 2012.01.
21. Kurihara, Y, Kanki, T, Aoki, Y, Hirota, Y, Saigusa, T, Uchiumi, T, Dongchon Kang, 「Mitophagy plays an essential role in reducing mitochondrial production of reactive oxygen species and mutation of mitochondrial DNA by maintaining mitochondrial quantity and quality in yeast」, 287, 7, 2012.01.
22. Matsumoto, S, Uchiumi, T, Saito, T, Yagi, M, Takazaki, S, Kanki, T, Dongchon Kang, 「Localization of mRNAs encoding human mitochondrial oxidative phosphorylation proteins」, 12, 8, 2012.03.
23. Morimoto, N, Miyazaki, K, Kurata, T, Ikeda, Y, Matsuura, T, Dongchon Kang, Ide, T, Abe, K, 「Effect of mitochondrial transcription factor a overexpression on motor neurons in amyotrophic lateral sclerosis model mice」, 90, 8, 2012.01.
24. Oba, T, Yasukawa, H, Hoshijima, M, Sasaki, K, Futamata, N, Fukui, D, Mawatari, K, Nagata, T, Kyogoku, S, Ohshima, H, Minami, T, Nakamura, K, Dongchon Kang, Yajima, T, Knowlton, K U, Imaizumi, T, Cardiac-specific deletion of SOCS-3 prevents development of left ventricular remodeling after acute myocardial infarction, 59, 14, 2012.02.
25. Wollen Steen, K, Doseth, B, M, P W, Akbari, M, Dongchon Kang, Falkenberg, M, Slupphaug, G, mtSSB may sequester UNG1 at mitochondrial ssDNA and delay uracil processing until the dsDNA conformation is restored, 11, 11, 2012.12.
26. Shinya Takazaki, Yoshito Abe, Yamaguchi, T, Mikako Yagi, Ueda, T, Dongchon Kang, Hamasaki Naotaka, Arg 901 in the AE1 C-terminal tail is involved in conformational change but not in substrate binding, 8, 2012.03.
27. Mikako Yagi, Takeshi Uchiumi, Shinya Takazaki, Okuno Bungo, Masatoshi Nomura, Yoshida, S, Kanki, T, Dongchon Kang, p32/gC1qR is indispensable for fetal development and mitochondrial translation: importance of its RNA-binding ability, Nucleic Acids Res, 40, 20, 2012.10.
28. Matsumoto, S., Uchiumi, T., Tanamachi, H., Saito, T., Yagi, M., Takazaki, S., Kanki, T., Kang, D., Ribonucleoprotein Y-box-binding protein-1 regulates mitochondrial oxidative phosphorylation (OXPHOS) protein expression after serum stimulation through binding to OXPHOS mRNA,, Biochem J , 443, 573-584, 2012.04.
29. Takazaki, S., Abe, Y., Yamaguchi, T., Yagi, M., Ueda, T., Kang, D., Hamasaki, N., Arg 901 in the AE1 C-terminal tail is involved in conformational change but not in substrate binding,, Biochim Biophys Acta , 1818, 658-665, 2012.03.
30. Matsumoto, S., Uchiumi, T., Saito, T., Yagi, M., Takazaki, S., Kanki, T., Kang, D., Localization of mRNAs encoding human mitochondrial oxidative phosphorylation proteins,, Mitochondrion, 12, 391-398, 2012.03.
31. Morimoto, N., Miyazaki, K., Kurata, T., Ikeda, Y., Matsuura, T., Kang, D., Ide, T., Abe, K. , Effect of mitochondrial transcription factor a overexpression on motor neurons in amyotrophic lateral sclerosis model mice,, J Neurosci Res, 2012.02.
32. Wollen Steen, K., Doseth, B., M, P. W., Akbari, M., Kang, D., Falkenberg, M., Slupphaug, G., mtSSB may sequester UNG1 at mitochondrial ssDNA and delay uracil processing until the dsDNA conformation is restored,, DNA Repair (Amst) , 11, 82-91, 2012.01.
33. Kurihara, Y., Kanki, T., Aoki, Y., Hirota, Y., Saigusa, T., Uchiumi, T., Kang, D., Mitophagy plays an essential role in reducing mitochondrial production of reactive oxygen species and mutation of mitochondrial DNA by maintaining mitochondrial quantity and quality in yeast,, J Biol Chem, 287, 3265-3272, 2012.01.
34. Aoki, Y., Kanki, T., Hirota, Y., Kurihara, Y., Saigusa, T., Uchiumi, T., Kang, D., FrePhosphorylation of Serine 114 on Atg32 mediates mitophagy,, Mol Biol Cell, 22, 3206-3217, 2011.09.
35. Guo, J., Zheng, L., Liu, W., Wang, X., Wang, Z., Wang, Z., French, A. J., Kang, D., Chen, L., Thibodeau, S. N., Liu, W., Frequent Truncating Mutation of TFAM Induces Mitochondrial DNA Depletion and Apoptotic Resistance in Microsatellite-Unstable Colorectal Cancer, Cancer Res, 71, 2978-2987, 2011.04.
36. Kang, D., Importance of mitochondrial genome in multiple cellular functions: A central role of TFAM in its maintenance,, Research Signpost, 69-88, 2011.03.
37. Amamoto, R., Yagi, M., Song, Y., Oda, Y., Tsuneyoshi, M., Naito, S., Yokomizo, A., Kuroiwa, K., Tokunaga, S., Kato, S., Hiura, H., Samori, T., Kang, D., Uchiumi, T., Mitochondrial p32/C1QBP is highly expressed in prostate cancer and is associated with shorter prostate-specific antigen relapse time after radical prostatectomy, Cancer Sci, 102, 639-647, 2011.03.
38. Amano, J., Masuyama, N., Hirota, Y., Tanaka, Y., Igawa, Y., Shiokawa, R., Okutani, T., Miyayama, T., Nanami, M., Ishigai, M., Antigen-dependent internalization is related to rapid elimination from plasma of humanized anti-HM1.24 monoclonal antibody, Drug Metab Dispos, 38, 2339-2346, 2010.09.
39. Ruhanen, H., Borrie, S., Szabadkai, G., Tyynismaa, H., Jones, A. W., Kang, D., Taanman, J. W.,Yasukawa, T., Mitochondrial single-stranded DNA binding protein is required for maintenance of mitochondrial DNA and 7S DNA but is not required for mitochondrial nucleoid organisation, Biochim Biophys Acta, 1803, 931-939, 2010.08.
40. Schumann, G., Canalias, F., Joergensen, P. J., Kang, D., Lessinger, J. M.,Klauke, R., IFCC reference procedures for measurement of the catalytic concentrations of enzymes: corrigendum, notes and useful advice., Clin Chem Lab Med, 48, 615-21, 2010.05.
41. Sekiguchi, K., Akiyoshi, K., Okazaki, N., Yamada, H., Suzuki, M., Maeda, T., Suenobu, S., Izumi, T.,Kang, D., PLEDs in an infant with congenital protein C deficiency: a case report, Clin Neurophysiol, 121, 800-1, 2010.05.
42. Uchida, Y., Mochimaru, T., Morokuma, Y., Kiyosuke, M., Fujise, M., Eto, F., Eriguchi, Y., Nagasaki, Y., Shimono, N.,Kang, D., Clonal spread in Eastern Asia of ciprofloxacin-resistant Escherichia coli serogroup O25 strains, and associated virulence factors. , J Antimicrob Agents, 35, 444-50, 2010.05.
43. Yamaguchi, T., Fujii, T., Abe, Y., Hirai, T., Kang, D., Namba, K., Hamasaki, N.,Mitsuoka, K., Helical image reconstruction of the outward-open human erythrocyte band 3 membrane domain in tubular crystals., J Struct Bio, 169, 406-412, 2010.05.
44. Uchida, Y., Mochimaru, T., Morokuma, Y., Kiyosuke, M., Fujise, M., Eto, F., Harada, Y., Kadowaki, M., Shimono, N., Kang, D., Geographic distribution of fluoroquinolone-resistant Escherichia coli strains in Asia., Antimicrobial Agents, 35, 387-391, 2010.05.
45. Uchida, Y., Mochimaru, T., Morokuma, Y., Kiyosuke, M., Fujise, M., Eto, F., Harada, Y., Kadowaki, M., Shimono, N.,Kang, D. , Geographic distribution of fluoroquinolone-resistant Escherichia coli strains in Asia., J Antimicrob Agents, 35, 387-91, 2010.04.
46. Uchiumi, T., Ohgaki, K., Yagi, M., Aoki, Y., Sakai, A., Matsumoto, S.,Kang, D., ERAL1 is associated with mitochondrial ribosome and elimination of ERAL1 leads to mitochondrial dysfunction and growth retardation., Nucleic Acids Res., 2010.04.
47. Takazaki, S., Abe, Y., Yamaguchi, T., Yagi, M., Ueda, T., Kang, D., Hamasaki, N, Mutation of His 834 in human anion exchanger 1 affects substrate binding., Biochim Biophys Acta, 1798, 903-908, 2010.03.
48. Yamaguchi, T., Ikeda, Y., Abe, Y., Kuma, H., Kang, D., Hamasaki, N.,Hirai, T., Structure of the membrane domain of human erythrocyte anion exchanger 1 revealed by electron crystallography. , J Mol Biol, 397, 179-189, 2010.03.
49. Fukuoh, A., Ohgaki, K., Hatae, H., Kuraoka, I., Aoki, Y., Uchiumi, T., Jacobs, H. T.,Kang, D., DNA conformation-dependent activities of human mitochondrial RNA polymerase., Genes Cells, 14, 1029-42, 2009.08.
50. Pohjoismaki, J. L., Goffart, S., Tyynismaa, H., Willcox, S., Ide, T., Kang, D., Suomalainen, A., Karhunen, P. J., Griffith, J. D., Holt, I. J.,Jacobs, H. T., Human heart mitochondrial DNA is organized in complex catenated networks containing abundant four-way junctions and replication forks., J Biol Chem, 284, 21446-57, 2009.08.
51. Hokazono, E., Osawa, S., Nakano, T., Kawamoto, Y., Oguchi, Y., Hotta, T., Kayamori, Y., Kang, D., Cho, Y., Shiba, K.,Sato, K., Development of a new measurement method for serum calcium with chlorophosphonazo-III, Ann Clin Biochem, 46, 296-301, 2009.07.
52. Sumitani, M., Kasashima, K., Ohta, E., Kang, D.,Endo, H., Association of a novel mitochondrial protein M19 with mitochondrial nucleoids., J Biochem, 146, 725-732, 2009.07.
53. Ishimura, M., Saito, M., Ohga, S., Hoshina, T., Baba, H., Urata, M., Kira, R., Takada, H., Kusuhara, K., Kang, D.,Hara, T., Fulminant sepsis/meningitis due to Haemophilus influenzae in a protein C-deficient heterozygote treated with activated protein C therapy, Eur J Pediatr, 168, 673-7., 2009.06.
54. Ono, M., Aoki, Y., Masumoto, M., Hotta, T., Uchida, Y., Kayamori, Y.,Kang, D., High-dose penicillin G-treatment causes underestimation of serum albumin measured by a modified BCP method, Clin. Chim. Acta, 407, 75-76, 2009.04.
55. Hayashi, Y., Yoshida, M., Yamato, M., Ide, T., Wu, Z., Ochi-Shindou, M., Kanki, T., Kang, D., Sunagawa, K., Tsutsui, H., Nakanishi, H., Reverse of age-dependent memory impairment and mitochondrial DNA damage in microglia by an overexpression of human mitochondrial transcription factor a in mice. , J Neurosci , 28, 8624-8634., 2008.06.
56. Hojo, S., Tsukimori, K., Kinukawa, N., Hattori, S., Kang, D., Hamasaki, N., Wake, N. Decreased maternal protein S activity is associated with fetal growth restriction., Thromb Res , 123, 55-59., 2008.06.
57. Ishimura, M., Saito, M., Ohga, S., Hoshina, T., Baba, H., Urata, M., Kira, R., Takada, H., Kusuhara, K., Kang, D., Hara, T., Fulminant sepsis/meningitis due to Haemophilus influenzae in a protein C-deficient heterozygote treated with activated protein C therapy., Eur J Pediatr, 2008.06.
58. Ohga, S., Ideguchi, H., Kato, J., Ishimura, M., Takada, H., Harada, N., Kawanaka, H., Hattori, Y., Kang, D., Hamasaki, N., Hara, T., Thromboembolic Complications in Splenectomized Patients with Dominantly Inherited beta-Thalassemia., Acta Haematol , 120 31-35, 2008.06.
59. Urata, M., Koga-Wada, Y., Kayamori, Y., Kang, D., Platelet contamination causes large variation as well as overestimation of mitochondrial DNA content of peripheral blood mononuclear cells., Ann Clin Biochem 45, 513-514, 2008.06.
60. Ohgaki, K. Kanki, T. Fukuoh, A. Kurisaki, H. Aoki, Y. Ikeuchi, M. Kim, S. H. Hamasaki, N. Kang, D., The C-terminal tail of mitochondrial transcription factor a markedly strengthens its general binding to DNA, J Biochem, 141, 201-211, 2007.02.
61. Goto, Y. Hayashi, R. Kang, D. Yoshida, K., Acute loss of transcription factor E2F1 induces mitochondrial biogenesis in HeLa cells, J Cell Physiol, 209、923-934, 2006.12.
62. Kanaji, T. Watanabe, K. Hattori, S. Urata, M. Iida, H. Kinoshita, S. Kayamori, Y. Kang, D. Hamasaki, N., Factor XII gene (F12) -4C/C polymorphism in combination with low protein S activity is associated with deep vein thrombosis, Thromb Haemost, 2006.12.
63. Ichibangase, T. Hamabe, C. Ohba, Y. Kishikawa, N. Nakashima, K. Kayamori, Y. Kang, D. Hamasaki, N. Kuroda, N., Study on immunocapture-chemiluminescence assay of lipase activity in a biological sample, Luminescence, 21:62-66, 2006.10.
64. Abe, Y. Hamasaki, T. Turusaki, S. Takazaki, S. Jin, X. Kang, D. Hamasaki, N., A simple search of TM segments in polytopic membrane protein using matrix-assisted laser desorption ionization time-of-flight mass spectrometry, Protein Pept Lett, 13: 761-767, 2006.08.
65. Yonezawa, Y. Kuriyama, I. Fukuoh, A. Muta, T. Kang, D. Takemura, M. Kato, I. Yoshida, H. Mizushina, Y., nhibitory effect of coenzyme Q on eukaryotic DNA polymerase gamma and DNA topoisomerase II activities on the growth of a human cancer cell line, Cancer Sci, 97: 716-723, 2006.08.
66. Takazaki, S. Abe, Y. Kang, D. Li, C. Jin, X. Ueda, T. Hamasaki, N., The functional role of arginine 901 at the C-terminus of the human anion transporter band 3 protein, J Biochem, 139: 903-912, 2006.05.
67. Yamaguchi, H. Kajitani, K. Dan, Y. Furuichi, M. Ohno, M. Sakumi, K. Kang, D. Nakabeppu, Y., MTH1, an oxidized purine nucleoside triphosphatase, protects the dopamine neurons from oxidative damage in nucleic acids caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, Cell Death Differ, 13: 551-563, 2006.04.
68. Sakai, Y. Oda, H. Yoshimura, D. Furuichi, M. Kang, D. Iwai, S. Hara, T. Nakabeppu, Y., The GT to GC single nucleotide polymorphism at the beginning of an alternative exon 2C of human MTH1 gene confers an amino terminal extension that functions as a mitochondrial targeting signal, J Mol Med, 84: 660-670, 2006.04.
69. Kajitani, K. Yamaguchi, H. Dan, Y. Furuichi, M. Kang, D. Nakabeppu, Y. , MTH1, an oxidized purine nucleoside triphosphatase, suppresses the accumulation of oxidative damage of nucleic acids in the hippocampal microglia during kainate-induced excitotoxicity, J Neurosci, 26: 1688-1698, 2006.02.
70. Li, C.Y. Takazaki, S. Jin, X.R. Kang, D. Abe, Y. Hamasaki, N. , Identification of Oxidized Methionine Sites in Erythrocyte Membrane Protein using LC/ESI MS Peptide Mapping, Biochemistry, 2006.01.
71. Kinoshita S, Iida H, Inoue S, Watanabe K, Kurihara M, Wada Y, Tsuda H, Kang D, Hamasaki N, Protein S and protein C gene mutations in Japanese deep vein thrombosis patients, Clin Biochem, 38, 10, 38: 908-915, 2005.01.
72. Ikeuchi M, Matsusaka H, Kang D, Matsushima S, Ide T, Kubota T, Fujiwara T, Hamasaki N, Takeshita A, Sunagawa K, Tsutsui H, Overexpression of mitochondrial transcription factor a ameliorates mitochondrial deficiencies and cardiac failure after myocardial infarction, Circulation, 112, 5, 112: 683-690, 2005.01.
73. Hara K, Okamoto M, Aki T, Yagita H, Tanaka H, Mizukami Y, Nakamura H, Tomoda A, Hamasaki N, Kang D, Synergistic enhancement of TRAIL- and tumor necrosis factor alpha-induced cell death by a phenoxazine derivative, Mol Cancer Ther, 4, 7, 4: 1121-1127, 2005.01.
74. Urata M, Wada Y, Kim S, Chumpia W, Kayamori Y, Hamasaki N, Kang D, High-Sensitivity Detection of the A3243G Mutation of Mitochondrial DNA by a Combination of Allele-Specific PCR and Peptide Nucleic Acid-Directed PCR Clampin, Clin Chem, 50, 11, 50: 2045-2051, 2004.01.
75. Sunayama J, Ando Y, Itoh N, Tomiyama A, Sakurada K, Sugiyama A, Kang D, Tashiro F, Gotoh Y, Kuchino Y, Kitanaka, Physical and functional interaction between BH3-only protein Hrk and mitochondrial pore-forming protein p32, Cell Death Differ, 11, 7, 11: 771-781, 2004.01.
76. Kanki T, Ohgaki K, Gaspari M, Gustafsson CM, Fukuoh A, Sasaki N, Hamasaki N, Kang D, Architectural role of TFAM in maintenance of human mitochondrial DNA, Mol Cell Biol, 24: 9823-9834, 2004.01.
77. Kanki T, Nakayama H, Sasaki N, Takio K, Alam TI, Hamasaki N, Kang D, Mitochondrial nucleoid and transcription factor A, Ann N Y Acad Sci, 1011, 1011: 61-68, 2004.01.
78. Chumpia, W., Ohsato, T., Kuma, H., Ikeda, S., Hamasaki, N. and Kang, D., Affinity purification of antibodies by using Ni2+-resins on which inclusion body-forming proteins are immobilized., Protein Expression and Purification, 32, 1, 32, 147-150., 2003.01.
79. Yoshida, Y., Izumi, H., Torigoe, T., Ishiguchi, H., Itoh, H., Kang, D. and Kohno, K., p53 Physically Interacts with Mitochondrial Transcription Factor A and Differentially Regulates Binding to Damaged DNA., Cancer Res, 63, 13, 63, 3729-3734., 2003.01.
80. Okamaoto, M., Ohsato, T., Nakada, K., Isobe, K., Spelbrink, J., Hayashi, J.I., Hamasaki, N. and Kang, D., Ditercalinium chloride, a pro-anticancer drug, intimately associates with mammalian mitochondrial DNA and inhibits its replication., Curr. Genet., 43, 5, 43, 364-370., 2003.01.
81. Suematsu, N., Tsutsui, H., Wen, J., Kang, D., Ikeuchi, M., Ide, T., Hayashidani, S., Shiomi, T., Kubota, T., Hamasaki, N. and Takeshita, A., Oxidative stress mediates tumor necrosis factor-alpha-induced mitochondrial DNA damage and dysfunction in cardiac myocytes., Circulation, 107, 10, 107, 1418-1423., 2003.01.
82. Alam, T.I., Kanki, T., Muta, T., Ukaji, K., Abe, Y., Nakayama, H., Takio, K., Hamasaki, N. and Kang, D., Human mitochondrial DNA is packaged with TFAM., Nucleic Acids Res, 31, 6, 31, 1640-1645., 2003.01.
83. Ohsato, T., Ishihara, N., Muta, T., Umeda, S., Ikeda, S., Mihara, K., Hamasaki, N. and Kang, D., Mammalian mitochondrial endonuclease G: digestion of R-loops and localization in intermembrane space., Eur. J. Biochem, 269, 23, 269, 5675-5770., 2002.01.
84. Iwaasa, M., Tatewaki, H., Ohno, T., Okubo, K., Hamasaki, N. and Kang, D., Genomic cloning and promoter analysis of a mouse anion exchanger 3 (AE3) gene., DNA Sequence, 13, 5, 13, 251-255., 2002.01.
85. Nagata, T., Kishi, H., Liu, Q.L., Matsuda, T., Imanaka, T., Tsukada, K., Kang, D. and Muraguchi, A., The regulation of DNAse activities in subcellular compartments of activated thymocytes., Immunology, 105, 4, 105, 399-406., 2002.01.
86. Takamatsu, C., Umeda, S., Ohsato, T., Ohno, T., Abe, Y., Fukuoh, A., Shinagawa, H., Hamasaki, N. and Kang, D., Regulation of mitochondrial D-loops by transcription factor A and single-stranded DNA-binding protein., EMBO Rep, 3, 5, 3, 451-456, 2002.01.
87. Iwaasa, M., Umeda, S., Ohsato, T., Takamatsu, C., Fukuoh, A., Iwasaki, H., Shinagawa, H., Hamasaki, N. and Kang, D., 1-Methyl-4-phenylpyridinium ion (MPP+), a toxin that can cause Parkinsonism, alter branched structures of DNA., J. Neurochem, 82, 30-37., 2002.01.
88. Umeda, S., Tang, Y., Okamoto, M., Hamasaki, N., Schon, E.A. and Kang, D., Both heavy strand replication origins are active in partially duplicated human mitochondrial DNAs., Biochem. Biophys. Res. Commun, 286, 4, 286, 681-687., 2001.01.
89. Tsutsui, H., Ide, T., Shiomi, T., Kang, D., Hayashidani, S., Suematsu, N., Wen, J., Utsumi, H., Hamasaki, N. and Takeshita, A., 8-oxo-dGTPase, which prevents oxidative stress-induced DNA damage, increases in the mitochondria from failing hearts., Circulation, 104, 24, 104, 2883-2885., 2001.01.
90. Iwase, M., Gotoh, D., Urata, M., Kang, D., Hamasaki, N., Yoshinari, M. and Fujishima, M., Clinical features of diabetic patients with 0.01-0.1% heteroplasmy A3243G mutation in leukocyte mitochondrial DNA., Diabetes Res Clin Pract, 54, 3, 54, 215-217., 2001.01.
91. Ide, T., Tsutsui, H., Hayashidani, S., Kang, D., Suematsu, S., Nakamura, K., Utsumi, H., Hamasaki, N. and Takeshita, A., Mitochondrial DNA damage and dysfunction associated with oxidative stress in failing hearts following myocardial infarction., Circ. Res, 88, 5, 88, 529-535., 2001.01.
92. Umeda, S., Muta, T., Ohsato, T., Takamatsu, C., Hamasaki, N. and Kang, D., Umeda, S., Muta, T., Ohsato, T., Takamatsu, C., Hamasaki, N. and Kang, D. (2000) The D-loop structure of human mitochondrial DNA is destabilized directly by 1-methyl-4-phenylpyridinium ion (MPP+), a parkinsonism-causing toxin, Eur. J. Biochem, 267, 1, 267, 200-206., 2000.01.
93. Soltys, B.J., Kang, D. and Gupta, R.S., Localization of P32 protein (gC1q-R) in mitochondria and at specific extramitochondrial locations in normal tissues., Histochem. Cell. Biol, 114, 3, 114, 245-255., 2000.01.
94. Ohno, T., Umeda, S., Hamasaki, N. and Kang, D., Binding of human mitochondrial transcription factor A, an HMG box protein, to a four-way DNA junction., Biochem. Biophys. Res. Commun., 271, 2, 271, 492-498., 2000.01.
95. Miyako, K., Takamatsu, C., Umeda, S., Tajiri, T., Furuichi, M., Nakabeppu, Y., Sekiguchi, M., Hamasaki, N., Takeshige, K. and Kang, D., Accumulation of adenine DNA glycosylase-sensitive sites in human mitochondrial DNA., J. Biol. Chem, 275, 16, 275, 12326-12330., 2000.01.
96. Shimura-Miura, H., Hattori, N., Kang, D., Miyako, K., Nakabeppu, Y. and Mizuno, Y., Increased 8-oxo-dGTPase in the mitochondria of substantia nigral neurons in Parkinson's disease., Ann. Neurol, 46, 6, 46, 920-924., 1999.01.
97. Cheng X, Kanki T, Fukuoh A, Ohgaki K, Takeya R, Aoki Y, Hamasaki N, Kang D, PDIP38 associates with proteins constituting mitochondrial DNA nucleoid, J Biochem, 138: 673-678.