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Yoshinao Oda Last modified date：2024.04.16

Professor / Department of Anatomic Pathology
Department of Basic Medicine
Faculty of Medical Sciences


Graduate School
Department of Pathological Sciences
Graduate School of Medical Sciences
Undergraduate School
Department of Medicine
School of Medicine
九州大学病院
Administration Post
Other


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Homepage
https://kyushu-u.elsevierpure.com/en/persons/yoshinao-oda
　Reseacher Profiling Tool　Kyushu University Pure
Phone
092-642-6061
Fax
092-642-5968
Academic Degree
MD. PhD
Country of degree conferring institution (Overseas)
No
Field of Specialization
Surgical and molecular pathology of human tumor
Total Priod of education and research career in the foreign country
02years00months
Outline Activities
Research: Surgical pathology of bone and soft tissue tumor, Multidrug resistance gene expression of human solid tumor, Oncogene and tumor suppressor gene in human sarcoma

Education: Lecture and practical education of surgical and molecular pathology, macroscopic and microscopic examination of human tumor

Social activities: Diagnostic pathology and cytology for the practical work in the refered hospital. President of Japanese Society of Pathology, President of Japanese Division of International Academy of Pathology
Research
Research Interests
  • Spatial multi-omics analysis to elucidate the tumor microenvironment of soft-tissue sarcomas and search for metabolically targeted therapies.
    keyword : Soft tissue sarcoma, tumor microenvironment, spatial multi-omics analysis, tumor metabolism
    2023.05～2023.08.
  • Investigation of novel immuno biomarker for malignant bone and soft tissue tumor
    keyword : immunotherapy, malignant bone and soft tissue tumor, biomarker
    2016.04～2020.06.
  • Systematic survey for molecular target in translocation associated and non-translocation associated soft tissue sarcoma
    keyword : Malignant soft tissue tumor, molecular target, translocation
    2013.04～2016.03.
  • Alteration of signal pathway and the possibility of molecular target therapy in malignant soft tissue tumors
    keyword : Malignant soft tissue tumor, mTOR, STAT3, pAkt
    2009.05～2012.05.
  • Ckemokine receptor and angiogenesis in malignant bone and soft tissue tumors
    keyword : Malignant bone and soft tssue tumor, VEGF, CXCR4
    2006.04～2009.05.
  • Molecular genetic abnormalities and their usefulness for diagnosis and prediction of prognosis in soft-tissue sarcomas
    keyword : Soft tissue sarcoma, molecular pathology, prognostic factor
    2000.04～2002.03Molecular genetic abnormalities and their usefulness for diagnosis and prediction of prognosis in soft-tissue sarcomas.
  • Expression of multidrug resistant related genes in human malignant solid tumors
    keyword : Malignant bone and soft tissue tumor, gynecological tumor, pediatric tumor, multidrug resistance, molecular biology
    1996.10～2003.12Expression of multidrug resistance gene in human solid tumors.
  • Molecular abnormalities of cell cycle regulators in malignant bone and soft-tissue tumor
    keyword : malignant bone and soft tissue tumor, cell cycle regulator genes and protein
    2003.04Molecular abnormalities of cell cycle regulators in malignant bone and soft-tissue tumor.
Academic Activities
Books
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Reports
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1. Oda Y, Tsuneyoshi M , Recent advances of molecular pathology in soft tissue sarcoma: Their implications for diagnosis, patient’s prognosis, and molecular target therapy in the future
, Cancer Sci 100(2): 200-208, 2009 (Corresponding), 2009.02.
2. Oda Y, Tsuneyoshi M , Expression of multidrug resistance-related molecules and Y-box-binding protein-1 in soft-tissue sarcomas.
, Nova Scientific Publisher (Corresponding), 2008.10.
Papers
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1. Izumi T, Oda Y, Hasegawa T, Kawai A, Sonobe H, Nakanishi Y, Takahira T, Kobayashi C, Yamamoto H, Tamiya S, Yokoyama R, Hirohashi S, Iwamoto Y, Tsuneyoshi M, Dysadherin expression as a significant prognostic factor and as a determinant of histological features in synovial sarcoma: special reference to its inverse relationship with E-cadherin expression., Am J Surg Pathol 31; 85-94, 2007. (Corresponding), 2007.01.
2. Oda Y, Yamamoto H, Tamiya S, Matsuda S, Tanaka K, Yokoyama R, Iwamoto Y, Tsuneyoshi M:, CXCR4 and VEGF expression in the primary site and the metastatic site of human
osteosarcoma: Analysis within a group of patients, all of whom developed lung
metastasis., Mod Pathol 19: 738-45, 2006. (corresponding), 2006.08.
3. Oda Y, Yamamoto H, Takahira T, Kobayashi C, Kawaguchi K, Tateishi N, Nozuka Y, Tamiya S, Tanaka K, Matsuda S, Yokoyama R, Iwamoto Y, Tsuneyoshi M:, Frequent alteration of p16INK4a/p14ARF and p53 pathways of round cell
appearance in myxoid/round cell liposarcoma: Altered p53 gene and reduced
p14ARF expression correlates with poor prognosis., J Pathol 207; 410-421, 2005. (Corresponding), 10.1002/path.1848, 207, 4, 410-421, 2005.01.
4. Oda Y, Saito T, Tateishi N, Ohishi Y, Tamiya S, Yamamoto H, Yokoyama R, Uchiumi T, Iwamoto Y, Kuwano M, Tsuneyoshi M, ATP-binding cassette superfamily transporter gene expression in human soft tissue sarcoma., Int J Cancer 114: 854-862, 2005 (Corresponding), 10.1002/ijc.20589, 114, 6, 854-862, 2005.01.
5. Oda Y, Takahira T, Kawaguchi K, Yamamoto H, Tamiya S, Matsuda S, Tanaka K,wamoto Y, Tsuneyoshi M:, Low-grade fibromyxoid sarcoma versus low-grade myxofibrosarcoma in the
extremities and trunk. Clinicopathologic and immunohistochemical study with
special emphasis on the alteration of cell cycle regulators., Histopathology 45; 29-38, 2004 (Corresponding), 10.1111/j.1365-2559.2004.01886.x, 45, 1, 29-38, 2004.01.
6. Saito T, Oda Y, Kawaguchi K, Yamamoto H, Sugimachi K, Tateishi N, Tanaka K,Matsuda S, Iwamoto Y, Ladanyi M, Tsuneyoshi M:, E-cadherin mutation and Snail overexpression as alternative mechanisms of
E-cadherin inactivation in synovial sarcoma., Oncogene 23: 8629-8638, 2004, 10.1038/sj.onc.1207960, 23, 53, 8629-8638, 2004.01.
7. Oda Y, Ohishi Y, Saito T, Hinoshita E, Uchiumi T, Kinukawa N, Iwamoto Y, Kohno K, Kuwano M, Tsuneyoshi M, Nuclear expression of Y box-binding protein-1 correlates with P-glycoprotein and
topoisomerase II-apha expression, and poor prognosis in synovial sarcoma., J Pathol 199; 251-258, 2003, 10.1002/path.1282, 199, 2, 251-258, 2003.01.
8. Oda Y, Takahira T, Kawaguchi K, Yamamoto H, Tamiya S, Matsuda S, Tanaka K, Kinukawa N, Iwamoto Y, Tsuneyoshi M:, Alterations of cell cycle regulators in myxofibrosarcoma. With special emphasis
on their prognostic implications., Human Pathol 34; 1035-1042, 2003, 2003.01.
9. Oda Y, Tamiya S, Oshiro Y, Hachitanda Y, Kinukawa N, Iwamoto Y, Tsuneyoshi M, Reassessment of malignant fibrous histiocytoma of soft parts and its
clinicopathologic prognostic factors., Pathol Int 52; 595-606, 2002, 2002.01.
10. Ohishi Y, Oda Y, Uchiumi T, Kobayashi H, Hirakawa T, Miyamoto S, Kinukawa N, Nakano H, Kuwano M, Tsuneyoshi M:, ATP-binding casstte superfamily transporter gene expression in human ovarian
carcinoma, Clin Cancer Res 8; 3767-3775, 2002, 8, 12, 3767-3775, 2002.01.
11. Oda Y, Miyajima K, Kawaguchi K, Tamiya S, Oshiro Y, Hachitanda Y, Oya M, Iwamoto Y, Tsuneyoshi M, Pleomorphic leiomyosarcoma: Clinicopathologic and immunohistochemical study with special emphasis on its distinction from ordinary leiomyosarcoma and
malignant fibrous histiocytoma., Am J Surg Pathol 25; 1030-1038, 2001, 10.1097/00000478-200108000-00007, 25, 8, 1030-1038, 2001.01.
12. Oda Y, Sakamoto A, Saito T, Kawauchi S, Iwamoto Y, Tsuneyoshi M:, Molecular abnormalities of p53, MDM2 and H-ras in synovial sarcoma., Mod Pathol 13: 994-1004, 2000., 10.1038/modpathol.3880180, 13, 9, 994-1004, 2000.01.
13. Oda Y, Sakamoto A, Shinohara N, Ohga T, Uchiumi T, Kohno K, Tsuneyoshi M, Kuwano M, Iwamoto Y, Nuclear expression of YB-1 protein correlates with P-glycoprotein expression in
human osteosarcoma., Clin Cancer Res 4: 2273-2277, 1998, 4, 9, 2273-2277, 1998.01.
Presentations
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Awards
  • Pathology of soft tissue sarcomas- From a morphological to a molecular biological approach
Educational
Educational Activities
For student: Human pathology

For post graduate student: Molecular pathology of bone and soft tissue tumors
Other Educational Activities
  • 2022.12.
  • 2022.10.
  • 2022.05.
  • 2021.11.
  • 2021.05.
  • 2021.10.
  • 2021.11.
  • 2020.10.
  • 2019.05.
  • 2019.10.
  • 2018.06.
  • 2018.10.
  • 2017.06.
  • 2017.04.
  • 2015.05.
  • 2014.12.
  • 2014.02.
  • 2013.12.
  • 2012.05.
  • 2012.10.
  • 2012.11.
  • 2012.12.
  • 2011.08.
  • 2010.11.
  • 2009.05.
  • 2009.09.
  • 2008.06.
  • 2006.05.
  • 2001.09.
Social
Professional and Outreach Activities
Diagnostic pathology in the refered hospital

International Society of Bone and Soft Tissue Pathology　Officers At-Large-Non-US (2013-2017) President-elect (2019-)President (2021)

Japanese Devision of International Academy of Pathology, Council Member (2010-), Permanent secretary (2016-2018) President-elect (2019-2021)President（2021-2023） Past-President(2023-).


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