Kyushu University Academic Staff Educational and Research Activities Database
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Tomohiko Akahoshi Last modified date:2019.06.06

Associate Professor / Center of Integration of Advanced Medicine, Life Science and Innovative Technology
Department of Advanced Medical Initiatives
Faculty of Medical Sciences


Graduate School
Undergraduate School
Other Organization
Administration Post
Other


E-Mail
Homepage
http://www.congre.co.jp/kyushu-u/surg2/
Phone
092-642-6222
Fax
092-642-6224
Academic Degree
Doctor of phylosophy
Country of degree conferring institution (Overseas)
No
Field of Specialization
Endoscopic surgery, Portal hypertension, abdominal emergency medicine
Total Priod of education and research career in the foreign country
00years00months
Outline Activities
2002~2003  Medical resercher in University of Carlifornia (USA)
Research
Research Interests
  • The efficacy of Adipose tissue derived stem cell on liver failure or liver cirrhosis
    keyword : liver failure
    2010.04~2012.12.
  • The effective training for acute care surgery
    keyword : acute care surgery
    2010.04~2011.12.
  • Portal hypertension
    Abnormal microcirculation in cirrhotic liver
    Hypersplenism
    keyword : Liver cirrhosis, Portal hypertension, splenomegaly
    2008.04~2008.12.
Current and Past Project
  • Adipose derived mesenchymal stem cells (ADSC) have an ability to diffrentiate a variety of cell such as muscle, hepatocyte and so on. Therefore, these cell is expected as a new therapy for organ failure in the patiets. Recently, not only the ability of differentiation but also paracrine effect of the stem cells is noted and increasingly reported. Our research progect found that ADSC product VEGF, HGF and TGF, which are important cytocine for tissue healing. We are working now for future application of human treatment.
Academic Activities
Reports
1. Laparoscopic splenectomy.
2. Akahoshi T. Hashizume M, Electromagnetic thermoablation to treat thrombocytopenia in cirrhotic and hypersplenic rats.
J Gastroenterol Hepatol
, J Gastroenterol Hepatol. , 2011.07.
Papers
1. Akahoshi T, Sarcopenia is a predictive factor for prolonged intensive care unit stays in high-energy blunt trauma patients, Acute Medicine & Surgery, 2016.08.
2. Sumida K, Shimoda S, Iwasaka S, Hisamoto S, Kawanaka H, AKahoshi T, Ikegami T, Akashi K, Characteristics of splenic CD8+ T cell exhaustion in patients with hepatitis C, Clin Exp Immunol , doi: 10.1111/cei., 174, 1, 172-178, 2013.08.
3. Kinjo N, Kawanaka H, Akahoshi T, Maehara Y, Hepatic vein waveform and splenomegaly predict improvement of prothrombin time after splenectomy in hepatitis C virus-related cirrhotic patients., Hepatol Res, doi: 10.1111/hepr.12040, 43, 9, 933-941, 2013.09.
4. Tsutsumi N, Tomikawa M, Uemura M, Akahoshi T, Image-guided laparoscopic surgery in an open MRI operating theater., Surg Endosc. , 1007/s00464-012-2737, 27, 6, 2178-2184, 2013.01.
5. Akahoshi T, Merits of prophylactic sclerotherapy for esophageal varices concomitant unresectable hepatocellular carcinoma: Prospective randomized study., Dig Endosc. , doi: 10.1111/den.12119, 2013.05.
6. Akahoshi T, Tomikawa M, Korenaga D, Ikejiri K, Saku M, Takenaka K. Maehara Y, Laparoscopic splenectomy with peginterferon and ribavirin therapy for patients with hepatitis C virus cirrhosis and hypersplenism., Surg Endosc. 2010 Aug 19, 2010.08.
7. Akahoshi T, Long-term results of endoscopic Histoacryl injection sclerotherapy for gastric variceal bleeding: a 10-year experience., Surgery, 10.1067/msy.2002.119501, 131, 1, S176-S181, 131(1): 176-181, 2002.01.
8. Tomohiko Akahoshi, Role of the spleen in liver fibrosis in rats may be mediated by transforming growth factor beta-1., Journal of Gastroenterlogy and Hepatology, 10.1046/j.1440-1746.2002.02667.x, 17, 1, 59-65, 17(1): 59-65, 2002.01.
9. Akahoshi T, Higashi H, Takeuchi H, Muto Y., Neuroendocrine carcinoma in liver , a case report and literature review. Surgery Today
Surg Today.
, Surg Today., 2010;40(2):185-9., 2010.01.
10. Tomohiko Akahoshi, Selective cyclooxygenase(COX)inhibition causes damage to portal hypertensive gastric mucosa
Role of nitric oxide and NF-kapperB, The FASEB Journal, 19, 9, 1163-1165, 2005.07.
Presentations
1. Utility of real time navigation system by open MRI for laparoscopic surgery.
2. The significance of surgery for gastrointestinal variceal bleeding..
3. The strategy for esophageal varices in the patients with VP3,4 HCC.
4. Complication of laparoscopic splenectomy in cirrhotic patients.
5. Emergency system for esophagogastric variceal bleeding in kyushu university .
Awards
  • The role of splenic immunosystem on liver fibrosis.