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Satoru Kidoaki Last modified date:2019.06.14

Professor / Research Field of Biomedical and Biphysical Chemistry
Department of Applied Molecular Chemistry
Institute for Materials Chemistry and Engineering


Graduate School
Undergraduate School
Other Organization


E-Mail
Homepage
http://www.cm.kyushu-u.ac.jp/mbbmc_imce_new/
Phone
092-802-2507
Fax
092-802-2509
Academic Degree
Ph.D.
Field of Specialization
Biophysical Chemistry・Bioengineering
Outline Activities
Biophysical chemistry for the basis of molecular design of the tissue-engineering materials

1. Mechanobio-materials to manipulate cell functions for biomedical enginneering
2. Protein biomechanics: Study on the mechanistic aspect of protein adsorption and protein-protein interactions
3. Matrix engineering: Development of the tissue-engineering matrix, scaffold, and devices
4. Physico-chemical study on the regulation of the higher-ordered structure and transport property of DNA
5. Biophysical chemistry on the mesoscopic systems: Study on the mechanism for molecular self-organization
Research
Research Interests
  • Mechanobio-materials: Design of micromechanical extracellular environment to manipulate cellular functions and behaviors
    keyword : Nanobiomechanics, Mechanobiology, Mechanobio-materials, Mechanotaxis
    2001.06.
  • Protein biomechanics: Mechanistic and thermodynamical studies on the protein-materials, protein-protein interactions
    keyword : Molecular force measurement
    1997.04.
  • Biomatrix engineering: Development of tissue engineering scaffold and drug delivery matrix with electrospinning methodology
    keyword : Cell manipulation matrix
    2002.06.
Academic Activities
Books
1. Satoru Kidoaki, "Mechanobio-materials: Design of elastically-micropatterned hydrogels to manipulate cell mechanotaxis and motility-coupled functions" in "Recent Advances in Mechanobiology", The Shanghai Scientific and Technological Literature Publishing House, 2012.11.
Reports
1. S. Kidoaki, Mechanics in cell adhesion and motility on the elastic substrates, Journal of Biomechanical Science and Engineering, 5, 218-228, 2010.04.
2. S. Kidoaki and T. Matsuda, Mechanistic aspects of protein/material interaction probed by AFM, Colloids & Surfaces B: Biointerfaces, 23, 153-163, 2002.01.
Papers
1. Misato Iwashita, Hatsumi Ohta, Takahiro Fujisawa, Minyoung Cho, Makoto Ikeya, Satoru Kidoaki, Yoichi Kosodo, Brain-stiffness-mimicking tilapia collagen gel promotes the induction of dorsal cortical neurons from human pluripotent stem cells, Scientific reports, 10.1038/s41598-018-38395-5, 9, 1, 2018.12, The mechanical properties of the extracellular microenvironment, including its stiffness, play a crucial role in stem cell fate determination. Although previous studies have demonstrated that the developing brain exhibits spatiotemporal diversity in stiffness, it remains unclear how stiffness regulates stem cell fate towards specific neural lineages. Here, we established a culture substrate that reproduces the stiffness of brain tissue using tilapia collagen for in vitro reconstitution assays. By adding crosslinkers, we obtained gels that are similar in stiffness to living brain tissue (150–1500 Pa). We further examined the capability of the gels serving as a substrate for stem cell culture and the effect of stiffness on neural lineage differentiation using human iPS cells. Surprisingly, exposure to gels with a stiffness of approximately 1500 Pa during the early period of neural induction promoted the production of dorsal cortical neurons. These findings suggest that brain-stiffness-mimicking gel has the potential to determine the terminal neural subtype. Taken together, the crosslinked tilapia collagen gel is expected to be useful in various reconstitution assays that can be used to explore the role of stiffness in neurogenesis and neural functions. The enhanced production of dorsal cortical neurons may also provide considerable advantages for neural regenerative applications..
2. Atsushi Sakai, Yoshihiro Murayama, Kei Fujiwara, Takahiro Fujisawa, Saori Sasaki, Satoru Kidoaki, Miho Yanagisawa, Increasing Elasticity through Changes in the Secondary Structure of Gelatin by Gelation in a Microsized Lipid Space, ACS Central Science, 10.1021/acscentsci.7b00625, 4, 4, 477-483, 2018.04, Even though microgels are used in a wide variety of applications, determining their mechanical properties has been elusive because of the difficulties in analysis. In this study, we investigated the surface elasticity of a spherical microgel of gelatin prepared inside a lipid droplet by using micropipet aspiration. We found that gelation inside a microdroplet covered with lipid membranes increased Young's modulus E toward a plateau value E∗ along with a decrease in gel size. In the case of 5.0 wt % gelatin gelled inside a microsized lipid space, the E∗ for small microgels with R ≤ 50 μm was 10-fold higher (35-39 kPa) than that for the bulk gel (∼3 kPa). Structural analysis using circular dichroism spectroscopy and a fluorescence indicator for ordered beta sheets demonstrated that the smaller microgels contained more beta sheets in the structure than the bulk gel. Our finding indicates that the confinement size of gelling polymers becomes a factor in the variation of elasticity of protein-based microgels via secondary structure changes..
3. H. Ebata, A. Yamamoto, Y. Tsuji, S. Sasaki, K. Moriyama, T. Kuboki, S. Kidoaki, Persistent random deformation model of cells crawling on a gel surface, Sci. Rep., 8, 5153, 2018.03.
4. Kousuke Moriyama, Satoru Kidoaki, Cellular Durotaxis Revisited
Initial-Position-Dependent Determination of the Threshold Stiffness Gradient to Induce Durotaxis, Langmuir, 10.1021/acs.langmuir.8b02529, 2018.01, Directional cell movement from a softer to a stiffer region on a culture substrate with a stiffness gradient, so-called durotaxis, has attracted considerable interest in the field of mechanobiology. Although the strength of a stiffness gradient has been known to influence durotaxis, the precise manipulation of durotactic cells has not been established due to the limited knowledge available on how the threshold stiffness gradient (TG) for durotaxis is determined. In the present study, to clarify the principles for the manipulation of durotaxis, we focused on the absolute stiffness of the soft region and evaluated its effect on the determination of TG required to induce durotaxis. Microelastically patterned gels that differed with respect to both the absolute stiffness of the soft region and the strength of the stiffness gradient were photolithographically prepared using photo-cross-linkable gelatins, and the TG for mesenchymal stem cells (MSCs) was examined systematically for each stiffness value of the soft region. As a result, the TG values for soft regions with stiffnesses of 2.5, 5, and 10 kPa were 0.14, 1.0, and 1.4 kPa/μm, respectively, i.e., TG markedly increased with an increase in the absolute stiffness of the soft region. An analysis of the area and long-axis length for focal adhesions revealed that the adhesivity of MSCs was more stable on a stiffer soft region. These results suggested that the initial location of cells starting durotaxis plays an essential role in determining the TG values and furthermore that the relationship between the position-dependent TG and intrinsic stiffness gradient (IG) of the culture substrate should be carefully reconsidered for inducing durotaxis; IG must be higher than TG (IG ≥ TG). This principle provides a fundamental guide for designing biomaterials to manipulate cellular durotaxis..
5. K. Tamada, E. Usukura, Y. Yanase, A. Ishijima, T. Kuboki, S. Kidoaki, K. Okamoto., LSPR-mediated high axial-resolution fluorescence imaging on a silver nanoparticle sheet, PLOS One, 12, 12, e0189708, 2017.12.
6. S. Masuda, Y. Yanase, E. Usukura, S. Ryuzaki, P. Wang, K. Okamoto, T. Kuboki, S. Kidoaki, and K. Tamada, High-Resolution Imaging of a Cell-Attached Nanointerface Using a Gold-Nanoparticle Two-Dimensional Sheet, Scientific Reports, 7, 3720, 2017.06.
7. Tomo Kurimura, Yoshiko Takenaka, Satoru Kidoaki, Masatoshi Ichikawa, Fabrication of Gold Microwires by Drying Gold Nanorods Suspensions, Adv. Mater. Interf., DOI: 10.1002/admi.201601125, 1601125, 2017.04.
8. Naohiko Shimada, Minako Saito, Sayaka Shukuri, Sotaro Kuroyanagi, Thasaneeya Kuboki, Satoru Kidoaki, Takeharu Nagai, Atsushi Maruyama, Reversible monolayer/spheroid cell culture switching by UCST-type thermoresponsive ureido polymers, ACS Applied Mater. Interf., DOI: 10.1021/acsami.6b07614, 8, 31524-31529, 2016.11.
9. T. Kuboki, S. Kidoaki, Fabrication of elasticity-tunable gelatinous gel for mesenchymal stem cell culture, Methods Mol. Biol., DOI 10.1007/978-1-4939-3584-0_25, 1416, 425-441, 2016.04.
10. Fahsai Kantawong, Thasaneeya Kuboki, Satoru Kidoaki, Redox gene expression of adipose-derived stem cells in response to soft hydrogel, Turkish Journal of Biology, 39, 682-691, 2015.06.
11. Ayaka Ueki, Satoru Kidoaki, Manipulation of cell mechanotaxis by designing curvature of the elasticity boundary on hydrogel matrix , Biomaterials, 41, 45-52, 2015, 2014.12.
12. Naohiko Shimada, Satoru Kidoaki, Atsushi Maruyama, Smart hydrogels exhibiting UCST-type volume changes under physiologically relevant conditions , RSC Advances, 4, 52346, 2014, 2014.10.
13. Thasaneeya Kuboki, Wei Chen, Satoru Kidoaki, Time-dependent migratory behaviors in the long-term studies of fibroblast durotaxis on a hydrogel substrate fabricated with a soft band, Langmuir, 30, 6187-6196., 2014.06.
14. Hiroyuki Sakashita, Satoru Kidoaki, Rectified cell migration on saw-like micro-elastically patterned hydrogels with asymmetric gradient ratchet teeth, PLOS One, 8, 10, e78067, 2013.10.
15. Hiroshi Yoshikawa, Takahito Kawano, Takehisa Matsuda, Satoru Kidoaki, Motomu Tanaka, Morphology and adhesion strength of myoblast cells on photocurable gelatin under native and non-native micromechanical environments, J. Phys. Chem. Part B, 117, 4081-4088, 2013.05.
16. T. Okuda, Y. Tahara, N. Kamiya, M. Goto, and S. Kidoaki, S/O-nanodispersion electrospun fiber mesh effective for sustained release of healthy plasmid DNA with the structural and functional Integrity, Journal of Biomaterials Science: Polymer Edition, 24, 1277-1290, 2013.01.
17. T. Kuboki, F. Kantawong, R. Burchmore, M.J. Dalby, and S. Kidoaki, 2D-DIGE proteomic analysis of mesenchymal stem cell cultured on the elasticity-tunable hydrogels, Cell Structure and Function, 37, 127-139,2012..
18. M. Horning, S. Kidoaki, T. Kawano, K. Yoshikawa, Rigidity-matching between cells and the extracellular matrix leads to the stabilization of cardiac conduction, Biophys. J., 102, 379-387, 2012.02.
19. T. Okuda and S. Kidoaki, Multidrug delivery systems with single formulation ~current status and future perspective~, Journal of Biomaterials and Nanobiotechnology, 3, 50-60, 2012.01.
20. T. Kawano and S. Kidoaki, Elasticity boundary conditions required for cell mechanotaxis on microelastically-patterned gels, Biomaterials, 32: 2725-2733 (2011)., 2011.01, 細胞は弾性基材表面の硬い領域を指向して運動する性質を示す(メカノタクシス)ことが知られていたが、その駆動のための表面弾性勾配の定量的条件は確立されておらず、メカノタクシスを系統的に誘導し制御することは不可能であった。本論文ではこの問題に対して、独自の弾性率可変ヒドロゲルのマイクロ弾性パターニング技術を確立することにより、細胞のメカノタクシスの誘導条件を初めて明確にした。その技術は細胞運動を操作する培養基材設計の一般的な基礎となるものである。.
21. N. Chen, A. Zinchenko, S. Kidoaki, M. Murata, K. Yoshikawa, Thermo-Switching of the Conformation of Genomic DNA in Solutions of Poly-(N-isopropylacrylamide), Langmuir, 26, 2995-2998 (2010)., 2010.03.
22. T. Okuda, K. Tominaga, S. Kidoaki, Time-programmed dual release formulation by multilayered drug-loaded nanofiber meshes, Journal of Controlled Release, 143, 2, 258-564, 143(2), 258-564 (2010)., 2010.02.
23. F. Ito, K. Usui, D. Kawahara, A. Suenaga, T. Maki, S. Kidoaki, H. Suzuki, M. Taiji, M. Itoh, Y. Hayashizaki, T. Matsuda, Protein-peptide specific interaction-driven hydrogel formation, hydrodynamic shear stress-dependent gel-to-sol reversibility and its potential application to injectable cartilage tissue, Biomaterials, 31, 58-66 (2009)., 2009.09.
24. K. Usui, T. Maki, F. Ito, A. Suenaga, S. Kidoaki, M. Itoh, M. Taiji, T. Matsuda, Y. Hayashizaki, H. Suzuki, Nanoscale elongating control of the self-assembled protein filament with the cysteine-introduced building blocks, Protein Science, 18, 960-969, 18, 960-969 (2009)., 2009.02.
25. S. Kidoaki and T. Matsuda, Microelastic gradient gelatinous gels to induce cellular mechanotaxis, Journal of Biotechnology, 133, 225-230 (2008)., 2008.01.
26. T. Maki, S. Kidoaki, K. Usui, H. Suzuki, M. Ito, F. Ito, Y. Hayashizaki, T. Matsuda, Dynamic force spectroscopy of the specific interaction between PDZ-domain and its recognition peptides, Langmuir, 23, 2668-2673 (2007)., 2007.01.
27. S. Kidoaki and T. Matsuda, Shape-engineered vascular endothelial cells: nitric oxide production, cell elasticity, and actin cytoskeletal features, Journal of Biomedical Materials Research: Part A, 81, 803-810, 81, 803-810 (2007)., 2007.06.
28. S. Kidoaki and T. Matsuda, Shape-engineered fibroblasts: cell elasticity and actin cytoskeletal features characterized by fluorescence and atomic force microscopy, Journal of Biomedical Materials Research: Part A, 81, 728-735, 2007.06.
29. S. Kidoaki, T. Matsuda, K. Yoshikawa, Relationship between apical membrane elasticity and stress fiber organization in fibroblasts analyzed by fluorescence and atomic force microscopy, Biomechan Model Mechanobiol, 5, 263-272 (2006)., 2006.11.
30. A. Idiris, S. Kidoaki, K. Usui, T. Maki, H. Suzuki, M. Ito, M. Aoki, Y. Hayashizaki, T. Matsuda, Force measurement on antigen-antibody interaction by atomic force microscopy using photograft-polymer spacer, Biomacromolecules, 10.1021/bm0502617, 6, 5, 2776-2784, 6, 2776-2784 (2005)., 2005.01.
31. S. Kidoaki, I.K. Kwon, T. Matsuda, Structural feature and mechanical property of in situ-bonded meshes of segmented polyurethane electrospun from mixed solvents, J. Biomed. Mater. Res. B, 10.1002/jbm.b.30336, 76B, 1, 219-229, 76, 219-229 (2005)., 2005.01.
32. T. Matsuda, M. Ihara, H. Inoguchi, I.K. Kwon, K. Takamizawa, S. Kidoaki, Mechano-active scaffold design of small-diameter artificial graft made of electrospun segmented polyurethane mesh fabrics, J. Biomed. Mater. Res. A, 10.1002/jbm.a.30260, 73A, 1, 125-131, 73, 125-131 (2005)., 2005.01.
33. I.K. Kwon, S. Kidoaki, T. Matsuda, Electrospun nano- to microfiber fabrics made of biodegradable copolyesters: structural characteristics, mechanical properties and cell adhesion potential, Biomaterials, 10.1016/j.biomaterials.2004.10.007, 26, 18, 3929-3939, 26(18), 3929-3939 (2005)., 2005.01.
34. S. Ohya, S. Kidoaki, T. Matsuda, Poly(N-isopropylacrylamide) (PNIPAAM)-grafted hydrogel surfaces: Interrelationship between microscopic structures and mechanical property of surface regions and cell adhesiveness, Biomaterials, 10.1016/j.biomaterials.2004.08.006, 26, 16, 3105-3111, 26, 3105-3111 (2005)., 2005.01.
35. S. Kidoaki, I.K. Kwon, T. Matsuda, Mesoscopic spatial designs of nano- and micron-fiber meshes for tissue-engineering matrix and scaffold based on newly devised multilayering and mixing electrospinning techniques, Biomaterials, 10.1016/j.biomaterials.2004.01.063, 26, 1, 37-46, 26(1), 37-46 (2005)., 2005.01.
36. T. Matsuda, I.K. Kwon, S. Kidoaki, Photocurable biodegradable liquid copolymer: synthesis of acrylate-endcapped trimethylene carbonate-based prepolymers, photocuring and hydrolysis, Biomacromolecues, 10.1021/bm034231k, 5, 2, 295-305, 5、295-305 (2004)., 2004.01.
37. T. Iwataki, S. Kidoaki, T. Sakaue, K. Yoshikawa, and S. S. Abramuchuk, Competition Between Compaction of Single Chains and Bundling of Multiple Chains in Giant DNA Molecules, J. Chem. Phys, 120、4004−4011 (2004)., 2004.01.
38. S. Kato, S. Kidoaki, T. Matsuda, Substrate-dependent Cellular Behaviors of Swiss 3T3 Fibroblasts and Activation of Rho Family during Adhesional and Spreading Processes, J. Biomed. Mater. Res, 10.1002/jbm.a.20012, 68A, 2, 314-324, 68, 314-324 (2004)., 2004.01.
39. T. Matsuda, J. Nagase, A. Gouda, Y. Hirano, S. Kidoaki, and Y. Nakayama, Phosphorylcholine-endcapped oligomer and block co-oligomer and surface biological reactivity, Biomaterials, 10.1016/S0142-9612(03)00344-2, 24, 24, 4517-4527, 24, 4517-4527 (2003)., 2003.01.
40. Y. Nakayama, A. Furumoto, S. Kidoaki and T. Matsuda, Photocontrol of Cell Adhesion and Proliferation by a Photoinduced Cationic Polymer Surface, Photochem. Photobiol., 10.1562/0031-8655(2003)077<0480:POCAAP>2.0.CO;2, 77, 5, 480-486, 77(5), 480-486 (2003)., 2003.01.
41. T. Okuda, S. Kidoaki , M. Ohsakia, Y. Koyama, K. Yoshikawa, Time-dependent complex formation of dendritic poly(L-lysine)s with plasmid DNA and correlation with in vitro transfection efficiencies, Org. Biomol. Chem., 1, 1270-1273 (2003)., 2003.01.
42. S.G.Starodoubtsev, S.Kidoaki, K.Yoshikawa, Interaction of Double-stranded T4 DNA with Cationic Gel of Poly(Diallyldimethylammonium Chloride), Biomacromolecules, 10.1021/bm025583e, 4, 1, 32-37, 4, 32-37 (2003)., 2003.01.
43. N. Yoshinaga, K. Yoshikawa, and S. Kidoaki, Multi-scaling in a long semi-flexible polymer chain in 2D, J. Chem. Phys., 10.1063/1.1475759, 116, 22, 9926-9929, 116, 9926-9929 (2002)., 2002.01.
44. S. Kidoaki, S. Ohya, Y. Nakayama, and T. Matsuda, Thermo-Responsive Property of N-isopropylacrylmide Graft-Polymerized Surfaces Measured with an Atomic Force Microscope, Langmuir, 17, 2402-2407 (2001)., 2001.01.
45. S. Kidoaki, Y. Nakayama, and T. Matsuda, Measuerment of Interaction Forces Between Proteins and Iniferter-Based Graft-Polymerized Surfaces with an Atomic Force Microscope in an Aqueous Media, Langmuir, 17, 1080-1087 (2001)., 2001.01.
46. T. Iwataki, Y. Yoshikawa, S. Kidoaki, D. Umeno, M. Kiji, M. Maeda, Cooperativity vs. Phase Transition in a Giant Single DNA Molecules, J. Am. Chem. Soc, 10.1021/ja000230d, 122, 41, 9891-9896, 122, 9891-9896 (2000)., 2000.01.
47. S. Kidoaki and T. Matsuda, Adhesion Forces of the Blood Plasma Proteins on Self-Assembled Monolayer Surfaces of Alkanethiolates with Different Functional Groups Measured by an Atomic Force Microscope, Langmuir, 15, 7639-7646 (1999)., 1999.01.
48. S. Kidoaki and K. Yoshikawa, Folding and Unfolding of a Giant Duplex-DNA in a Mixed Solution with Polycations, Polyanions, and Crowding Neutral Polymers, Biophys. Chem, 76, 133-143 (1999)., 1999.01.
49. N. Emi, S. Kidoaki, K. Yoshikawa and H. Saito, Gene Delivery Mediated by Polyarginine Requires a Formation of Big Carrier-Complex of DNA Aggregate, Biochem. Biophys. Res. Commun, 231, 421-424 (1997)., 1997.01.
50. V. V. Vasilevskaya, A. R. Khokhlov, S. Kidoaki and K. Yoshikawa, Structure of Collapsed Persistent Macromolecule: Toroid vs. Spherical Globule, Biopolymers, 41, 51-60 (1997)., 1997.01.
51. H. Noguchi, S. Saito, S. Kidoaki and K. Yoshikawa, Self Organized Nanostructure Constructed with a Single Polymer Chain., Chem. Phys. Lett, 261, 527-533 (1996)., 1996.01.
52. K. Yoshikawa, S. Kidoaki, M. Takahashi, V. V. Vasilevskaya and A. R. Khokhlov, Marked Discreteness on The Coil-Globule Transition of Single Duplex-DNA, Ber. Bunsen-Ges. Phys. Chem, 100, 876-880 (1996)., 1996.01.
53. S. Kidoaki and K. Yoshikawa, The Folded State of Long Duplex-DNA Chain Reflects Its Solution History, Biophys. J., 71, 932-939 (1996)., 1996.01.
Presentations
1. S. Kidoaki, Exercising mesenchymal stem cells through nomadic culture on heterogeneous field of matrix elasticity, Kyoto Winter School“Quantifying Dynamics of Life”, 2019.03.
2. H. Ebata, K. Moriyama, T. Kuboki, S. Kidoaki, Cell-type dependent durotaxis on micro-elastically heterogeneous gels, アクティブマター研究会2019, 2019.01.
3. S. Sasaki and S. Kidoaki, Precise multi-scaled control of surface wrinkle on the hydrogels, MRS-J 2018年会, 2018.12.
4. S. Kidoaki, K. Moriyamaa, T. Kuboki, R. Sawada, Y. Tsuji, H. Ebata, S. Sasaki, A. Yamamoto, K. Kono, K. Tanaka, Modulation of APC expression in mesenchymal stem cell during nomadic culture on heterogeneous field of elasticity, ABA-ASA2018, 2018.12.
5. H. Ebata, K. Moriyama, T. Kuboki, S. Kidoaki, Domain-size dependent cellular durotaxison micro-elastically stripe patterned gels, APEF2018, 2018.11.
6. R. Sawada, K. Moriyama, K. Tanaka, K. Kono, Y. Sato, H. Ebata, S. Sasaki, T. Kuboki, Comprehensive gene expression analysis of human mesenchymal stem cells cultured on the micro elastically triangle patterned gel matrix, TERMIS2018, 2018.09.
7. K. Moriyama, S. Kidoaki, Elasticity threshold of the gel matrix to manipulate migration and differentiation of mesenchymal stem cell, PhysCell2018, 2018.09.
8. H. Ebata, A. Yamamoto, Y. Tsuji, S. Sasaki, K. Moriyama, T. Kuboki, S. Kidoaki, Migration model of crawling cells driven by persistent fluctuation of cell shape, PhysCell2018, 2018.09.
9. S. Kidoaki, K. Moriyama, T. Kuboki, R. Sawada, Y. Tsuji, H. Ebata, S. Sasaki, A. Yamamoto, K. Kono, K. Tanaka, Modulation of APC expression in mesenchymal stem cell during nomadic culture on heterogeneous field of elasticity, PhysCell2018, 2018.09.
10. S. Kidoaki, Mechanobio-materials manipulating motility and functions of stem cells, OISTセミナー, 2018.07.
11. R. Sawada, K. Kono, K. Tanaka, Y. Sato, S. Kidoaki, Investigation of marker genes predicting osteogenic differentiation potential of human mesenchymal stem cells, ISSCR2018, 2018.06.
12. Satoru Kidoaki, Frustrated differentiation of mesenchymal stem cells induced by nomadic movement between stiff and soft region of hydrogel matrix, 2018 IMCE International Symposium, 2018.03.
13. Midori Toratani, Yukie Tuji, Hisato Hayashi, Takehisa Iwama, Masato Horikawa, and Satoru Kidoaki, Development of Cellulose Nanofiber-Based Dispersion Culture System for Mesenchymal Stem Cell Keeping Highly-Qualified Stemness
, 2017 Kyushu-Seibu/Pusan-Gyeongnam Joint Symposium on High Polymers(18th) and Fibers(16th), 2017.12.
14. Takahiro Fujisawa, and Satoru Kidoaki, Development of photo-cross-linked collagen gels keeping the native triple helix, 2017 Kyushu-Seibu/Pusan-Gyeongnam Joint Symposium on High Polymers(18th) and Fibers(16th), 2017.12.
15. Daoxiang Huang, Satoru Kidoaki , Fabrication of a micro fibrous gel matrix with tunable elasticity for selectively- capturing cancer cells, 2017 Kyushu-Seibu/Pusan-Gyeongnam Joint Symposium on High Polymers(18th) and Fibers(16th), 2017.12.
16. Satoru Kidoaki, Frustrated differentiation of mesenchymal stem cells induced by normadic migration between stiff and soft region of hydrogel matrix, ISMB2017, 2017.12.
17. Hiroyuki Ebata, Aki Yamamoto, and Satoru Kidoaki, Migration model based on persistent fluctuation of cell shape, SFS2017, 2017.11.
18. Satoru Kidoaki, Mechanobio-Materials Manipulating Motility and Functions of Stem Cells, 第55回日本生物物理学会年会, 2017.09.
19. S. Sasaki, H. Ebata, and S. Kidoaki, Surface Structural Control of Wrinkled gel for Cell Culture, IUMRS2017, 2017.08.
20. Satoru Kidoaki, Mechanobio-materials manipulating motility and functions of stem cells, ISOMRM2017, 2017.08.
21. T. Kuboki, F. Kantawong, and S. Kidoaki1 , Mechanotransduction and redox balance of stem cells, BMI2017, 2017.08.
22. Thasaneeya Kuboki, Fahsai Kantawong ,and Satoru Kidoaki, Mechanotrasduction and redox balance of stem cells, ISB2017, 2017.06.
23. Satoru Kidoaki, Hiroyuki Ebata, Rumi Sawada, Kouske Moriyama, Thasaneeya Kuboki, Ken Kono, Kazusa Tanaka, Saori Sasaki , Characterization of the frustrated differentiation of mesenchymal stem cells induced by nomadic migration between stiff and soft region of gel matrix, ISB2017, 2017.06.
24. Satoru Kidoaki, Kenta Mizumoto, Negative mechanotaxis of iPS cells observed on microelastically-patterned hydrogels, Single-Cell Biophysics: Measurement, Modulation, and Modeling, 2017.06.
25. Rumi Sawada, Ken Kono, Kazusa Tanaka, Yoji Sato, Kousuke Moriyama,  Hiroyuki Ebata, Saori Sasaki, Thasaneeya Kuboki, Satoru Kidoaki, Comprehensive gene expression analysis of human mesenchymal stem cells cultured on the micro elastically-striped pattern gel matrix, ISSCR2017, 2017.06.
26. Saori Sasaki, Hiroyuki Ebata, Takuya Ohzono, Satoru Kidoaki, Designing Wrinkled Hydrogels for Cell Manipulation, Gel Symposium 2017, 2017.03.
27. Satoru Kidoaki, Hiroyuki Ebata, Rumi Sawada, Kousuke Moriyama, Thasaneeya Kuboki, Ken Kono, Kazusa Tanaka, Satori Sasaki, Characterization of the frustrated differentiation of mesenchymal stem cells induced by normadic migration between stiff and soft region of gel matrix, Biophysical Society 61th Annual Meeting, 2017.02.
28. Hiroyuki Ebata, Kouske Hamano, Satoru Kidoaki, Analysis of dynamics of mechano-signal input for stem cells cultured on the micro-elastically patterned hydrogels, International polymer conference 2016, 2016.12.
29. Thasaneeya Kuboki, Satoru Kidoaki, Fahsai Kantawong, Mechanotransduction and redox signaling in stem cells, Mechanobiology of Disease, 2016.09.
30. THASANEEYA KUBOKI, Tomoki Matsuda, Takeharu Nagai, Hiroyuki Ebata, Satoru Kidoaki, Live imaging of paxillin in durotactic migrating cells on the microelastically patterned hydrogels, KJF-ICOMEP 2016, 2016.09.
31. THASANEEYA KUBOKI, Satoru Kidoaki, Surface elasticity tunable gelatinous gel for manipulation of stem cell fate determination and directional cell migration, 6th International Polymer Conference of Thailand, 2016.06.
32. Satoru Kidoaki, Kouske Hamano, THASANEEYA KUBOKI, Traction force microscopy of mesenchymal stem cells in mode of frustrated differentiation, 10th World Biomaterials Congress, 2016.05.
33. Thasaneeya Kuboki, Takeharu Nagai, Yoshiyuki Arai, Tomoki Matsuda, Satoru Kidoaki, Live imaging of paxillin in durotactic migrating cells on the micro-elastically patterned hydrogels, 日本機械学会第28回バイオエンジアリング講演会, 2016.01.
34. Satoru Kidoaki, Mechanobio-materials manipulating motility and functions of stem cells, 26th 2015 International Symposium on Micro-NanoMechatronics and Human Science, 2015.11.
35. Satoru Kidoaki, Traction force microscopy of mesenchymal stem cells in mode of frustrated differentiation, iCeMS International Symposium, Hierarchical Dynamics in Soft Materials and Biological Matter, 2015.09.
36. Fahasai Kantawong, Thasaneeya Kuboki, Satoru Kidoaki, Redox gene expression of adipose-derived stem cells in response to soft hydrogel, The 8th Asian-Pacific Conference on Biomechanics 2015, 2015.09.
37. Satoru Kidoaki, Traction force microscopy of mesenchymal stem cells in mode of frustrated differentiation, The 8th Asian-Pacific Conference on Biomechanics 2015, 2015.09.
38. Satoru Kidoaki, Ayaka Ueki, Manipulation of cell mechanotaxis by designing curvature of the elasticity boundary on hydrogel matrix, 27th European Conference on Biomaterials ESB2015, 2015.08.
39. Satoru Kidoaki, Traction force microscopy of mesenchymal stem cells in mode of frustrated differentiation, International Symposuim on Nanoarchitectonics for Mechanobiology (ISNM), 2015.07.
40. Wei Chen, Thasaneeya Kuboki, Satoru Kidoaki, Time-dependent migratory behaviors in the long-term studies of fibroblast durotaxis on a hydrogel substrate fabricated with a soft band, 248th ACS National Meeting, 2014.08.
41. Satoru Kidoaki, Mechanobio-Materials Manipulating Cell Motility and Functions, NIMS Conference 2014, 2014.07.
42. Thasaneeya Kuboki, Satoru Kidoaki, Time-dependent migratory behaviors in the long-term studies of fibroblast durotaxis on a hydrogel substrate fabricated with a soft band , International Society for Mechanobiology 2014, 2014.05.
43. Satoru Kidoaki, Mechaobio-materials manipulating cell motility and functions, International Society for Mechanobiology 2014, 2014.05.
44. Satoru Kidoaki*, Mechanobio-Materials Manipulating Cell Motility and Functions
, Joint international symposium on "Nature-inspired Technology(ISNIT) 2014" and "Engineering Neo-biomimetics V", 2014.02.
45. Satoru Kidoaki*, Mechanobio-materials manipulating cell motility and functions, The 17th SANKEN International Symposium 2014/ The 2nd International Symposium of Nano-Macro materials Devices and System Research Alliance Project, 2014.01.
46. Satoru Kidoaki*, "Mechanobio-Materials": Design of Elastically-Micropatterned Gels To Control Cell Mechanotaxis And Motility-Related Functions, The 15th International Conference on Biomedical Engineering, 2013.12.
47. Satoru Kidoaki*, Frustrated differentiation of mesenchymal stem cell cultured on microelastically-patterned photocurable gelatinous gels, The 7th World Congress on Biomimetics, Artificial Muscles and Nano-Bio(BAMN2013), 2013.08.
48. Thasaneeya Kuboki, Wei Chen, Satoru Kidoaki*, Controlling mechano-repellent cell migration induced by a micro-scale soft band on a hydrogel matrix, Sydney International Nanomedicine Conference, 2013.07.
49. Satoru Kidoaki, Takahito Kawano, Hiroyuki Sakashita, “Mechanobio-Materials”: Design of Elastically-Micropatterned Gels To Control Cell Mechanotaxis and Motility-Related Functions, IEEE-NMDC2012, 2012.10.
50. Satoru Kidoaki, Syuhei Jinnouchi, Frustrated Differentiation of Mesenchymal Stem Cell Cultured on Microelastically-Patterned Photocurable Gelatinous Gels, The 2012 International Conference on Flexible and Printed Electronics, 2012.09.
51. 奥田 竜也, 富永賢吾, 木戸秋 悟, Development of multidrug delivery system for biochemical modulation by nano-/micro-mesh technology
, 7th International Symposium on High-tech Polymer Materials (HTPM-VII), 2012.06.
Membership in Academic Society
  • Biophysical Society
  • Japanese Society for Medical and Biological Engineering
  • International Society of Mechanobiology
Educational
Other Educational Activities
  • 2011.04.
  • 2010.04.
  • 2009.04.
  • 2008.04.
  • 2008.04.