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OHYAMA YUKIKO Last modified date:2019.08.02

Lecturer / Maxillofacial Diagnostic and Surgical Sciences
Maxill Ofacial Surgery
Kyushu University Hospital


Graduate School


E-Mail
Phone
092-642-6452
Fax
092-642-6392
Academic Degree
PhD
Country of degree conferring institution (Overseas)
No
Field of Specialization
Oral Surgery, Immunology, Mobid Dentistry
Total Priod of education and research career in the foreign country
03years00months
Outline Activities
Research: Study on the pathogenesis of Sjogren's syndrome and IgG4 Related Disease. 
Education: Oral surgery and immunological research of oral mucosa. Reconstruction of the clinical skill training system of oral surgery field on dental school students and clinical residents.
Research
Research Interests
  • Study on the dysbiosis in the gut microbiota of patients with Sjögren's syndrome and IgG4 related disease.
    keyword : Sjögren's syndrome, IgG4 related disease, microbiota
    2017.02.
  • Study on the expression of TRP channel on human oral mucosa and genomic analysis of TRP channel in oral diseases.
    keyword : TRP channel Burning mouth syndrome
    2010.09.
  • Study on the mechanism of salivation abnormality in patients with Sjogren's syndrome
    keyword : Sjogren's syndrome. cevimeline hydrochloride
    2006.04.
  • Possible involvement of human T lymphotrophic virus type I in the pathogenesis of Sjogren's syndrome
    keyword : Sjogren's syndrome, autoimmune disease, HTLV-1
    1994.04Possible involvement of human T lymphotrophic virus type I in the pathogenesis of Sjogren's syndrome.
  • Pathogenesis of Sjograen's syndrome
    keyword : Sjogren's syndrome, autoimmune deisease
    1998.04Pathogenesis of Sjograen's syndrome.
Academic Activities
Papers
1. Moriyama Masafumi, Miho Ohta, S Furukawa, Yurie Mikami, Akihito Tanaka, T Maehara, Hayashida Jun-Nosuke, M Yamauchi, Noriko Ishiguro, Hayashida Jun-Nosuke, Shintaro Kawano, Yukiko Ohyama, Tamotsu Kiyoshima, Seiji Nakamura, The diagnostic utility of labial salivary gland biopsy in IgG4-related disease.
, Mod Rheumatol., Epub ahead of print, 2016.03.
2. Mayumi Shimizu, Kazutoshi Okamura, Y Kise, Y Takeshita, Hiroko Furuhashi, W Weerawanich, Moriyama Masafumi, Yukiko Ohyama, Sachiko Furukawa, Seiji Nakamura, Kazunori Yoshiura, Effectiveness of imaging modalities for screening IgG4-related dacryoadenitis and sialadenitis (Mikulicz's disease) and for differentiating it from Sjögren's syndrome (SS), with an emphasis on sonography., Arthritis Res Ther., 10.1186/s13075-015-0751-x., 23, 17, 223, 2015.08.
3. T Maehara, Moriyama Masafumi, Shintaro Kawano, Hayashida Jun-Nosuke, S Furukawa, Miho Ohta, Akihito Tanaka, M Yamauchi, Yukiko Ohyama, Tamotsu Kiyoshima, Seiji Nakamura, Cytokine profiles contribute to understanding the pathogenic difference between good syndrome and oral lichen planus: two case reports and literature review. , Medicine, 1097/MD.0000000000000704., 94, 14,
, 2015.04.
4. S Furukawa, Moriyama Masafumi, Shintaro Kawano, Akihito Tanaka, T Maehara, Hayashida Jun-Nosuke, Yuichi Goto, Tamotsu Kiyoshima, Hideki Shiratsuchi, Yukiko Ohyama, Miho Ohta, Yumi Imabayashi, Seiji Nakamura, Clinical relevance of Küttner tumour and IgG4-related dacryoadenitis and sialoadenitis., Oral Diseases, 10.1111/odi.12259. , 21, 257-262, 257-262, 2014.06.
5. Takahiro Fujinaga, Kumamaru Wataru, Tsuyoshi Sugiura, Yosuke Kobayashi, Yukiko Ohyama, TATSUYA IKARI, Mitsuho Onimaru, Naonari Akimoto, Rumi Jogo, Yasuharu Takenoshita, Biological characterization and analysis of metastasis-related genes in cell lines derived from the primary lesion and lymph node metastasis of a squamous cell carcinoma arising in the mandibular gingiva. , Int J Oncol. , 10.3892/ijo.2014.2332., 44, 5, 1614-1624, 2014.03.
6. Goro Sugiyama, Yukiko Ohyama, Tamotsu Kiyoshima, Mayumi Shimizu, Kaneki Eisuke, Yasuharu Takenoshita, Metastatic adenocarcinoma of the mandibular condyle from uterine cervix: Report of a case., Oral Scinece Internatilnal, org/10.1016/S1348-8643(13)00028-1, 11, 40-44, 40-44, 2014.01.
7. Moriyama Masafumi, Akihito Tanaka, T Maehara, Yukiko Ohyama, Mayumi Shimizu, H Nakashima, Hayashida Jun-Nosuke, S Shinozaki, S Kubo, S Furukawa, Seiji Nakamura, Clinical characteristics of Mikulicz's disease as an IgG4-related disease., Clin Oral Investig. , 10.1007/s00784-012-0905-z., 17, 9, 1995-2002, 1995-2002, 2013.12.
8. Hayashida Jun-Nosuke, Seiji Nakamura, Toyoshima Takeshi, Moriyama Masafumi, Masanori Sasaki, Eiji Kawamura, Yukiko Ohyama, Kumamaru Wataru, Kamemitsu Shirasuna, Possible involvement of cytokines, chemokines and chemokine receptors in the initiation and progression of chronic GVHD., Bone Marrow Transplant, 10.1021/bi2018128, 48, 1, 115-123, 115-123, 2013.01.
9. Moriyama Masafumi, Hayashida Jun-Nosuke, Toyoshima Takeshi, Yukiko Ohyama, Shinozaki S, Tanaka Akihiko, Maehara T, Seiji Nakamura, Cytokine/chemokine profiles contribute to understanding the pathogenesis and diagnosis of primary Sjögren's syndrome., Clin Exp Immunol., 169, 1, 17-26, 17-26, 2012.06.
10. Goro Sugiyama, Hiroshi Takeuchi, Nagano Kouki, jing gao, Yukiko Ohyama, Yoshihide Mori, Masato Hirata, Regulated Interaction of Protein Phosphatase 1 and Protein Phosphatase 2A with Phospholipase C-Related but Catalytically Inactive Protein., Biochemistry, 51, 16, 3394-3403, 3394-3403, 2012.04.
11. Mayumi Shimizu, Moriyama Masafumi, Kazutoshi Okamura, Toshiyuki Kawazu, Toru Chikui, Tazuko K. Goto, Yukiko Ohyama, Seiji Nakamura, Kazunori Yoshiura, Sonographic diagnosis for Mikulicz disease., Oral Med Oral Pathol Oral Radiol Endod. , 108, 1, 105-113, 105-113, 2009.07.
12. Deshmukh US, Ohyama Y, Bagavant H, Guo X, Gaskin F, Fu SM., Inflammatory stimuli accelerate Sjögren's syndrome-like disease in (NZB x NZW)F(1) mice., Arthritis Rheum., 58(5):1318-1323 , 2008.04.
13. Shimizu M, Yoshiura K, Nakayama E, Kanda S, Nakamura S, Ohyama Y, Nakamura N., Multiple sialolithiasis in the parotid gland with Sjogren's syndrome and its sonographic findings--report of 3 cases., Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 10.1016/j.tripleo.2004.04.014, 99, 1, 85-92, 99(1):85-92, 2005.01.
14. Kumamaru W, Nakamura S, Kadena T, Yamada A, Kawamura E, Sasaki M, Ohyama Y, Toyoshima T, Hayashida J, Itoh K, Shirasuna K, T-cell Receptor Vb gene usage by T cells reactive with the tumor-rejection antigennnn SART-1 in oral squamous cell carcinoma, Int J Cancer, 108(5):686-695, 2004.02.
15. Kawamura E, Nakamura S, Sasaki M, Ohyama Y, Kadena T, Kumamaru W, Shirasuna K., Accumulation of oligoclonal T cells in the infiltrating lymphocytes in oral lichen planus., J Oral Pathol Med., 32, 5, 282-289, 32(5):282-9., 2003.05.
16. Tsunawaki S, Nakamura S, Ohyama Y, Sasaki M, Ikebe-Hiroki A, Hiraki A, Kadena T, Kawamura E, Kumamaru W, Shinohara M, Shirasuna K., Possible function of salivary gland epithelial cells as nonprofessional antigen-presenting cells in the development of Sjogren's syndrome., J Rheumatol., 29, 9, 1884-1896, 29(9):1884-96., 2002.09.
17. Sasaki M, Nakamura S, Ohyama Y, Shinohara M, Ezaki I, Hara H, Kadena T, Kishihara K, Yamamoto K, Nomoto K, Shirasuna K., Accumulation of common T cell clonotypes in the salivary glands of patients with human T lymphotropic virus type I-associated and idiopathic Sjogren's syndrome., J Immunol., 164, 5, 2823-2831, 164(5):2823-31, 2000.03.
18. Ohyama Y, Nakamura S, Hara H, Shinohara M, Sasaki M, Ikebe-Hiroki A, Mouri T, Tsunawaki S, Abe K, Shirasuna K, Nomoto K., Accumulation of human T lymphotropic virus type I-infected T cells in the salivary glands of patients with human T lymphotropic virus type I-associated Sjogren's syndrome., Arthritis Rheum., 10.1002/1529-0131(199811)41:11<1972::AID-ART12>3.0.CO;2-M, 41, 11, 1972-1978, 41(11):1972-8., 1998.11.
19. Nakamura S, Ikebe-Hiroki A, Shinohara M, Ohyama Y, Mouri T, Sasaki M, Shirasuna K, Nomoto K., An association between salivary gland disease and serological abnormalities in Sjogren's syndrome., J Oral Pathol Med., 10.1111/j.1600-0714.1997.tb00243.x, 26, 9, 426-430, 26(9):426-30., 1997.10.
20. Mouri T, Nakamura S, Ohyama Y, Matsuzaki G, Shinohara M, Kishihara K, Hiroki A, Oka M, Shirasuna K, Nomoto K., T cell receptor V alpha and V beta gene usage by tumour-infiltrating lymphocytes in oral squamous cell carcinoma., Cancer Immunol Immunother., 10.1007/s002620050402, 45, 1, 61-61, 45(1):61., 1996.10.
21. Ohyama Y, Nakamura S, Matsuzaki G, Shinohara M,Ohyama Y, Oka M, Nomoto K., T-cell receptor V alpha and V beta gene use by infiltrating T cells in labial glands of patients with Sjogren's syndrome., Oral Surg Oral Med Oral Pathol Oral Radiol Endod., 10.1016/S1079-2104(05)80308-7, 79, 6, 730-737, 79(6):730-7., 1995.06.
Presentations
1. Mayumi Shimizu, Moriyama Masafumi, Kazutoshi Okamura, Toshiyuki Kawazu, Toru Chikui, YUKIKO OHYAMA, Sachiko Furukawa, Seiji Nakamura, Kazunori Yoshiura, Imaging diagnosis for IgG4-related dacryoadenitis and sialoadenitis, so called Mikulicz disease. , 12th International Symposium on Sjögren’s Syndrome, 2013.10.
2. Mayumi Shimizu, Kazutoshi Okamura, Moriyama Masafumi, YUKIKO OHYAMA, Seiji Nakamura, Kazunori Yoshiura, Imaging diagnosis for Sjögren’s syndrome by scintigraphy - comparison with sonography and sialography – , 12th International Symposium on Sjögren’s Syndrome, 2013.10.
Membership in Academic Society
  • Japanese Society of Oral Care
  • Japanese Society of Orofacial Pain
  • Japanese Society of Oro-Facial Neuronal Function
  • Japanese Association for Sjogren's Syndrome
  • Japanese Society of Oral Medicine
  • Japanese Society of Oral and Maxillofacial Surgeons
  • Japanese Stomatological Society
  • Japan Society for Oral Tumors
  • Japanese Society of Psychosomatic Dentistry
  • Japanese Society for Palliative Medicine
  • Japanese Society for Disability and Oral Health
Educational
Educational Activities
Clinical and practical training of oral surgery for undergraduate school students.
Reconstruction of the clinical skill training system of oral surgery field on dental school students and clinical residents.
Research guidance on the analysis of the mechanism of oral mucosa diseases to graduate school students.