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manabu nakazono Last modified date:2019.10.21

Assistant Professor / Department of Medico-Pharmaceutical Sciences
Department of Chemo-Pharmaceutical Sciences
Faculty of Pharmaceutical Sciences


Undergraduate School
Administration Post
Other


Academic Degree
Doctor of pharmaceutical sciences
Field of Specialization
Analytical sciences
Outline Activities
Research: The development of novel fluorescent and chemiluminescent reagents
The development of enzyme activity assay
Research
Research Interests
  • Development of novel luminescent reagent for highly sensitive analysis
    keyword : fluorescence, chemiluminescence
    1996.04Synthesis of highly sensitive luminescenct reagents Assay of repair enzyme activity for DNA damage Development of photoresponce reagent.
Academic Activities
Papers
1. Manabu Nakazono, Shinkoh Nanbu, Takeyuki Akita, Kenji Hamase, Synthesis, chemiluminescence, and application of 2,4-disubstituted phenyl 10-methyl-10λ4-acridine-9-carboxylates, Dyes and Pigments, 170, 107628, 2019.11.
2. Manabu Nakazono, Shinkoh Nanbu, Enhancement effect on the chemiluminescence of acridinium esters under neutral conditions, Luminescence, 33, 345-348, 2018.03.
3. Manabu Nakazono, Yuji Oshikawa, Mizuho Nakamura, Hidehiro Kubota, Shinkoh Nanbu, Strongly chemiluminescent acridinium esters under neutral conditions: synthesis, properties, determination and theoretical study, The Journal of Organic Chemistry, 82, 2450-2461, 2017.03.
4. Manabu Nakazono, Konen Obayashi, Yuji Oshikawa, Kazushi Tani, Genki Suenaga, Yukio Ando, Shinkoh Nanbu, Ryoichi Kuwano, Unsynmetric indolylmaleimides; synthesis, photophysical properties and amyloid detection, Journal of Photochemistry and Photobiology A: Chemistry, 289, 39-46, 2014.06.
5. Manabu Nakazono, Konen Obayashi, Kazumi Sasamoto, Katsumi Tomiyoshi, Genki Suenaga, Yukio Ando, Novel styrylbenzene derivatives for detecting amyloid deposits, Clinica Chimica Acta, 436, 27-34, 2014.05.
6. Manabu Nakazono, Kenichiro Saita, Yuji Oshikawa, Kazushi Tani, Shinkoh Nanbu, Kiyoshi Zaitsu, Fluorescence properties of 2-aryl substituted indoles, Spectrochimica Acta Part A, Molecular and bimolecular spectoroscopy, 78, 905-908, 2011, 2011.02.
7. Manabu Nakazono, Ai Jinguji, Shinkoh Nanbu, Ryoichi Kuwano, Zilong Zheng, Kenichiro Saita, Yuji Oshikawa, Yuta Mikuni, Tatsuhiro Murakami, Yi Zhao, Shigeki Sasaki, Kiyoshi Zaitsu, Fluorescence and chemiluminescence properties of indolylmaleimides: experimental and theoretical studies, Physical Chemistry Chemical Physics, 12, 9783-9793, 2010.08.
8. Hiroki Agawa, Manabu Nakazono, Shinkoh Nanbu, Kiyoshi Zaitsu, Chemiluminescence change of polyphenol dendrimers with different core molecules, Organic Letters, 10, 5171-5174, 2008.10.
9. Manabu Nakazono, Shinkoh Nanbu, Akihiro Uesaki, Ryoichi Kuwano, Manabu Kashiwabara, Kiyoshi Zaitsu , Bisindolylmaleimides with Large Stokes Shift and Long-lasting Chemiluminescence Properties, Organic Letters, 9, 3683-3686, 2007.08.
10. Manabu Nakazono, Akihiro Uesaki, Kiyoshi Zaitsu, The chemiluminescence mechanism of 3,4-bis(3-indolyl)-1H-pyrrole-2,5-dione, and the characteristics of chemiluminescence developed in the reaction with NaClO-H2O2 or antioxidants, Talanta, 70, 128-132, 2006.08.