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Toshihisa Kajiwara Last modified date:2017.05.26

Professor / Production system engineering
Department of Chemical Engineering
Faculty of Engineering


Graduate School
Undergraduate School


E-Mail
Homepage
http://rheolo1.chem-eng.kyushu-u.ac.jp/lab6HP/
Description about our research, publications and members .
Phone
092-802-2746
Fax
092-802-2796
Academic Degree
Doctor of Engineering
Field of Specialization
Chemical Engineering
Outline Activities
Polymer Processing : We have developed the computer simulation techniques for various kinds of processes encountered in the polymer processing. The prediction techniques of materials behavior in twin screw extruders can evaluate the effects of screw configulation and other conditions on the mixing performance. We also developed the various kinds of molding processes including the viscoelastic flow and deformation and use the explanation of physical mechanism for various phenomena appearing in the polymer processing. Our goal is the establishment of process analysis system for the whole process from materials to final products.
Biochemical Engineering : The development and use of scaffold are very important in the field of artificial organs or regenerative medicine. We are trying to the design of scaffold and its processing from the viewpoint of three-dimensional structure as well as material characteristics. The developed scaffold with optimal structure will be applied to the development of organoid formation technique of cell and artificial organs. We also study toward the development of the novel medical treatment based on the field of chemical engineering including the reaction and mass transfer.
Research
Research Interests
  • A Study on Proussing of Rubber Materials
    keyword : Rubber Materials,Thermosetting,Rubber Processsing
    2014.04.
  • Study on processing of functional inorganic-polymeric hybrid materials

    keyword : functional material, polymer composite
    2006.10.
  • Study on processing of a multi-layered polymer film
    keyword : multi-layered polymer film, polymer processing
    2006.04.
  • Study on Morphology-forecast technique of polymer blend
    keyword : polymer blend, Morphology
    2005.04.
  • Study on mixing technology and development of novel materials
    keyword : polymer materials, mixing, novel materials
    2002.04.
  • Study on Computer Simulation in Polymer Processing
    keyword : Polymer Processing, Numerical Simulation, CAE
    2002.04Study on Computer Simulation in Polymer Processing We have developed the computer simulation techniques for various kinds of processes encountered in the polymer processing. The prediction techniques of materials behavior in twin screw extruders cover the solid conveying, melting process and melt pumping and we can evaluate the effects of screw configulation and other conditions on the mixing performance. We also developed the various kinds of molding processes including the viscoelastic flow and deformation and use the explanation of physical mechanism for various phenomena appearing in the polymer processing. Keyword: Polymer Processing, Numerical Simulation, CAE Technique.
  • In Vitro Reconstruction of Hematopoietic Systems with Three Dimensional Culture of Bone Marrow Cells.
    keyword : ( bone marrow, hematopoietic stem cell, three dimensional culture, regenerative medicine
    2006.04Study on hematopoietic stem cell in three dimensional culture.
  • Development of Mass Culture Method of Embryonic Stem Cells.
    keyword : embryonic stem cell, mass culture, regenerative medicine
    2005.04Study on mass cultivation system for undifferentiated ES cells Keyword: Embryonic Stem Cell, Mass Cultivation System, Regenerative Medicine.
  • Study on Development of Hybrid Artificial Liver Support System
    keyword : hybrid artificial liver, bioreactor, artificial organ, regenerative medicine, stem cell
    2002.04Study on Development of Hybrid Artificial Liver Support System (HALSS) We have developed two types of HALSS that use hepatocyte organoid culture. One is a PUF-HALSS comprising a bioreactor using polyurethane foam (PUF). In the bioreactor hepatocytes were immobilized in the pores of PUF and formed spheroid, and maintained liver-specific functions for at least ten days in vitro. The other is a LLS-HALSS that used a bioreactor containing hollow fibers with a microregular arrangement. Hepatocytes were immobilized in the extracapillary space and formed organoids by centrifugation. LLS-HALSS achieved long term maintenance of liver-specific functions for at least two months in vitro. In animal experiments, each HALSS was effective in supporting liver function, stabilization of general conditions and recovery from liver failure state. These results indicate that these HALSS may be useful to treat liver failure patients until liver transplantation or until regeneration of the native liver. Keyword: Hybrid Artificial Liver, Bioreactor, Artificial Organ, Stem Cell.
  • Development of Three Dimensional Organoid Culture Method and Application to Regenerative Medicine.
    keyword : three dimensional culture, organoid, regenerative medicine, stem cell
    2002.04Study on Development of a Three Dimensional Organoid Culture System Keyword: Three Dimensional Culture, Organoid, Regenerative Medicine, Stem Cell.
Academic Activities
Presentations
1. Toshihisa Kajiwara, Yasuya Namayama, Hiroki Takemitsu, Satoshi Esaki, Takahide Takeuchi, Koichi Kimura, Hideki Tomiyama, Melt-Mixing by Pitched-Tip Kneading Disks in a Twin-Screw Extruder - Experimental Verification -, The XVIIth International Congress on Rheology (ICR2016), 2016.08.12.
Educational