Kyushu University Academic Staff Educational and Research Activities Database
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Yoshinori Katakura Last modified date:2019.06.12



Graduate School
Undergraduate School


Homepage
http://www.agr.kyushu-u.ac.jp/lab/crt/katakura/Site2/TOP.html
Lab of Cellular Regulation Technology, Department of Genetic Resources Technology, Graduate School of Bioresources and Bioenvironmental Sciences, Kyushu University .
http://www.sls.kyushu-u.ac.jp/skou_seigyo.html
Lab. of Cellular Regulation Technology, Division of Life Engineering, Graduate School of Systems Life Sciences, Kyushu University .
Academic Degree
Ph. D.
Field of Specialization
Cellular Regulation Technology
Outline Activities
[Research]
1. Elucidation of functionalities of food and its application to generation of anti-aging food.
2. Molecular basis for signaling cascades regulating senescence, aging and longevity and its application to anti-aging therapy
3. Regulation mechanisms of telomerase activity

[Education]
1. Lectures, "Systems Biological Science", "Cellular Functional Technology", "Anti-aging food technology", "Physical Science", "Analytical Chemistry Experiment", "Basic Bacterial Experiment", "Cellular Biology", "Molecular and Cellular Biology".
Research
Research Interests
  • Molecular basis for anti-aging foods
    keyword : Functional food, anti-aging
    2008.04Investigation on the functionalities of foods and their molecular basis.
  • Molecular basis for aging and its application to invenstion of anti-aging foods
    keyword : Cellular senescence, telomerase regulation
    1994.08Molecular basis of cellular senescence, aging and longevity, and its possible application to drug design..
  • Generation of antigen-specific human monoclonal antibody by in vitro immunization.
    keyword : human monoclonal antibody
    1995.04~2008.03Generation of antigen-specific human monoclonal antibody by in vitro immunization and phage display hybrid method..
  • Mass-production of recombinant protein in mammalian cells.
    keyword : Recombinant protein production, monoclonal antibody
    1994.08~2008.03Hyper-production of recombinant protein in mammalian cells.
Current and Past Project
  • The Research Institute for Biology and Food in Fukuoka Industrial Technology Center invented a new method for production of hydroxyapatite sheet which exhibits high-affinity for adhisive animal cells. Kyushu University and Astec Co. Ltd. collaborated with the institute to develop a novel 3 demension high density cell culture system for large-scale production of recombinant proteins.
Academic Activities
Reports
1. Rice allergen.
Papers
1. Yusuke Togo, Yujiro Higuchi, Yoshinori Katakura, Kaoru Takegawa, Early endosome motility mediates α-amylase production and cell differentiation in Aspergillus oryzae, J. Agric. Food Chem., 7, 1, 15757, 2017.11.
2. Hui Tan, Chong Zhao, Qinchang Zhu, Yoshinori Katakura, Hiroyuki Tanaka, Koichiro Ohnuki, Kuniyoshi Shimizu, Ursolic Acid Isolated from the Leaves of Loquat (Eriobotrya japonica) Inhibited Osteoclast Differentiation through Targeting Exportin 5, J. Agric. Food Chem., 67, 2, 3333-3340, 2019.03.
3. Zhao Chong, Haruka Matsuo, Shiori Onoue, Hiroaki Yamamoto, Hideyuki Ito, Yoshinori Katakura, Identification of polyphenols that repair the ultraviolet-B-induced DNA damage via SIRT1-dependent XPC/XPA activation, Journal of Functional Foods, 54, 119-127, 2019.03.
4. Gakuro Harada, Shiori Onoue, Chisato Inoue, Sakae Hanada, Yoshinori Katakura, Delphinidin-3-glucoside suppresses lipid accumulation in HepG2 cells, Cytotechnology, 70, 6, 1707-1712, 2018.12.
5. Zhao Chong, Haruka Matsuo, Mai Kuroda, Shuntaro Yamashita, Gopal Prasad Parajuli, Hira Kaji Manandhar, Kuniyoshi Shimizu, Yoshinori Katakura, Mushroom extract inhibits ultravilet B-induced cellular senescence in human keratinocytes, Cytotechnology, 70, 3, 1001-1008, 2018.06.
6. Keishi Kadooka, Mikako Sato, Takashi Matsumoto, Satoru Kuhara, Yoshinori Katakura, Tatsuya Fujimura, Pig testis extract augments adiponectin expression and secretion through the peroxisome proliferator-activated receptor signaling pathway in 3T3-L1 adipocytes, Cytotechnology, 70, 3, 983-992, 2018.06.
7. Momoko Hamano, Yurina Haraguchi, Tomoko Sayano, Chong Zyao, Yashiho Arimoto, Yui Kawano, Kazuki Moriyasu, Miyako Udono, Yoshinori Katakura, Takuya Ogawa, Hisanori Kato, Shigeki Furuya, SMARCD1 regulates senescence-associated lipid accumulation in hepatocytes, npj Aging Mech. Dis., 3, 11, 2017.08.
8. Kaoru Fujii, Kayoko Abe, Keishi Kadooka, Takashi Matsumoto, 片倉 喜範, Carnosine activates the CREB pathway in Caco-2 cells, Cytotechnology, 2017.06.
9. Shuntaro Yamashita, Kaoru Fujii, Chong Zhao, Hiroshi Takagi, 片倉 喜範, Involvement of the NFX1-repressor complex in PKC-delta-induced repression of hTERT transcription, JOURNAL OF BIOCHEMISTRY, 10.1093/jb/mvw038, 160, 5, 309-313, 2016.11.
10. Tomoko Sayano, Yuki Kawano, Wataru Kusada, Yashiho Arimoto, Kayoko Ezaki, Momoko Hamano, Miyako Udono, 片倉 喜範, Takuya Ogawa, 加藤久典, Yoshio Hirabayashi, Shigeki Furuya, Adaptive response to L-serine deficiency is mediated by p38 MAPK activation via deoxysphinganine in normal fibroblasts, FEBS Open Bio, 6, 303-316, 2016.04.
11. Zhao Chong, Takenori Sakaguchi, Kosuke Fujita, Hideyuki Ito, Norihisa Nishida, Nagatomo Akifumi, Yukimasa Tanaka, 片倉 喜範, Pomegranate-Derived Polyphenols Reduce Reactive Oxygen Species Production via SIRT3-Mediated SOD2 Activation, OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 10.1155/2016/2927131, 2016, 2927131, 2016.04.
12. 片倉 喜範, Lactobacillus brevis T2102 suppresses the growth of colorectal cancer cells by activating SIRT1, Journal of Functional Foods, 2016.01.
13. 片倉 喜範, Effect of Anserine/Carnosine Supplementation on Verbal Episodic Memory in Elderly People, Journal of Alzheimers Disease, 50, 149-159, 2015.12.
14. 片倉 喜範, Impaired ATP6V0A2 expression contributes to Golgi dispersion and glycosylation changes in senescent cells, SCIENTIFIC REPORTS, 10.1038/srep17342, 5, 2015.11.
15. 片倉 喜範, Mechanisms and consequences of carnosine-induced activation of intestinal epithelial cells, JOURNAL OF FUNCTIONAL FOODS, 10.1016/j.jff.2014.12.024, 13, 32-37, 2015.03.
16. 片倉 喜範, Molecular mechanisms for the p38-induced cellular senescence in normal human fibroblast, JOURNAL OF BIOCHEMISTRY, 10.1093/jb/mvu040, 156, 5, 283-290, 2014.11.
17. 片倉 喜範, 藤井薫, 小磯綾加, 平川標, 山下万貴子, Identification of anti-allergic lactic acid bacteria that suppress Ca2+ influx and histamine release in human basophilic cells, JOURNAL OF FUNCTIONAL FOODS, 10.1016/j.jff.2014.07.006, 10, 370-376, 2014.09.
18. 片倉 喜範, FOXO3a Potentiates hTERT Gene Expression by Activating c-MYC and Extends the Replicative Life-Span of Human Fibroblast, PLOS ONE, 10.1371/journal.pone.0101864, 9, 7, e101864, 2014.07.
19. 片倉 喜範, 山下万貴子, 原田額郎, 松本信英, 相葉佳洋, 市川明, 藤木司, 鵜殿美弥子, 樺山繁, 好田正, Pingbo Zhang, Hiroshi Fujii, 白畑 實隆, Suppression of immunoglobulin production in human peripheral blood mononuclear cells by monocytes via secretion of heavy-chain ferritin, Immunobiology, 10.1016/j.imbio.2013.08.011, 219, 2, 149-157, 2014.02.
20. 片倉 喜範, Gakuro Harada, Shin-ei Matsumoto, Makiko Yamashita, Kaoru Fujii, 白畑 實隆, In vitro immunization of Epstein-Barr virus-immortalized B cells augments antigen-specific antibody production, Cytotechnolgoy, 10.1007/s10616-013-9596-9, 65, 979-983, 2013.06.
21. 片倉 喜範, 小熊一郎, 山下俊太郎, 佐藤聡, 奧山和雄, Novel purification method of human IgG by using a thermo-responsive protein A, J. Chromatogr. A , 10.1016/j.chroma.2013.07.015, 1305, 149-153, 2013.04.
22. Yoshinori Katakura, Yu-Jin, Ko, Hui-Hun, Kim, Eun-Jung, Kim, Won-Sup, Lee, Gon-Sup, Kim, Chung-Ho, Ryu, Piceatannol inhibits mast cell-mediated allergic inflammation, Int. J. Mol. Med., 2012.11.
23. Yoshinori Katakura, Miyako Udono, Keishi Kadooka, Shuntaro Yamashita, Quantitative analysis of cellular senescence phenotypes using an imaging cytometer, Methods, 56, 383-388, 56: 383-388, 2012.05.
24. Makiko Yamashita, Akira Hitaka, Himiko Fujino, Takashi Matsumoto, Takanori Hasegawa, Fumiki Morimatsu, Tsukasa Fujiki, Yoshinori Katakura, Identification of immunopotentiating lactic acid bacteria that induce antibody production by in vitro-stimulated human peripheral blood mononuclear cells, Bioscience of Microbiota, Food and Health, 31:7-13, 2012.01.
25. Shuntaro Yamashita, Kaori Ogawa, Takahiro Ikei, Miyako Udono, Tsukasa Fujiki, Yoshinori Katakura, SIRT1 prevents replicative senescence of normal human umbilical cord fibroblast through potentiating the transcription of human telomerase reverse transcriptase gene, Biochem. Biophys. Res. Commun., 417: 630-634, 2012.01.
26. Keishi Kadooka, Asuka Imahayashi, Ayaka Koiso, Makiko Yamashita, Kiichiro Teruya, Takashi Matsumoto, Takanori Hasegawa, Fumiki Morimatsu, Yoshinori Katakura, Establishment of a novel method of screening anti-allergic lactic acid bacteria, Biosci. Biotechnol. Biochem.,, 75:1016-1018, 2011.05.
27. Tsukasa Fujiki, Miyako Udono, Yojiro Kotake, Makiko Yamashita, Sanetaka Shirahata, Yoshinori Katakura, NFAT5 regulates transcription of the mouse telomerase reverse transcriptase gene, Exp. Cell Res., 316, 3342-3350, 2010.05.
28. Tsukasa Fujiki, Miyako Udono, Takumi Miura, Santaka Shirahata, Yoshinori Katakura, Regulatory mechanisms of human and mouse telomerase reverse transcriptase gene transcription: distinct dependency on c-Myc, Cytotechnology, 10.1007/s10616-010-9276-y, 2010.04.
29. Yoshinori Katakura, Miyako Udono, Kazuyuki Katsuki, Hisaya Nishide, Yukiko Tabira, Takahiro Ikei, Makiko Yamashita, Tsukasa Fujiki, Sanetaka Shirahata, Protein kinase C δ plays a key role in cellular senescence programs of human normal diploid cells, J. Biochem, 146, 1, 87-93, 2009.04.
30. Kaichi Yoshizaki, Tsukasa Fujiki, Takahiro Tsunematsu, Makiko Yamashita, Miyako Udono, Sanetaka Shirahata, Yoshinori Katakura, Pro-senescent effect of hydrogen peroxide on cancer cells and its possible application to tumor suppuression, Biosci. Biotechnol. Biochem., 73, 2, 311-315, 2009.02.
31. Yeon Suk Jung, Shin-ei Matsumoto, Yoshinori Katakura, Makiko Yamashita, Kosuke Tomimatsu, Shigeru Kabayama, Kiichiro Teruya, Sanetaka Shirahata, Generation of human monoclonal antibodies against Propionibacterium acnes by applying the phage display method to human peripheral blood mononuclear cells immunized in vitro, Cytotechnol., 57: 169-175, 2008.09.
32. Miyako Udono, Tsukasa Fujiki, Makiko Yamashita, Kazuyuki Katsuki, Masaaki Funata Yusuke Imada, Kaichi Yoshizaki, Sanetaka Shirahata, Yoshinori Katakura, Construction of a regulatable cancer-specific adenoviral expression system using human telomerase reverse transcriptase gene promoter, Biosci. Biotechnol. Biochem., 72: 1638-1641, 2008.05.
33. Yeon Suk Jung, Shin-ei Matsumoto, Makiko Yamashita, Kosuke Tomimatsu, Kiichiro Teruya, Yoshinori Katakura, Sanetaka Shirahata, Propionibacterium acnes acts as an adjuvant in in vitro immunization of human peripheral blood mononuclear cells, Biosci. Biotechnol. Biochem., 71: 1963-1969, 2007.05.
34. Tsukasa Fujiki, Takumi Miura, Mariko Maura, Hiroshi Shiraishi, Yusuke Imada, Norihisa Uehara, Kosuke Tashiro, Sanetaka Shirahata, Yoshinori Katakura, TAK1 represses transcription of the human telomerase reverse transcriptase gene, Oncogene, in press, 2007.03.
Presentations
1. Ai Sawazaki, Yoshinori Katakura, Bungo Shirouchi, Masao Sato, Neural Morphometric Appraisal by Addition of Apolipoprotein E in Human Neuroblastoma Cell Line SH-SY5Y, International Symposium on Agriculture, Food, Environmental and Life Science in Asia, 2017.11.
2. Kaoru Fujii, Izuru Ohtsu, Mikako Sato, Yoshinori Katakura, Carnosine activates the anti-aging signal in the intestinal epithelial cells, Keystone Symposia Aging and Mechanisms of Aging-related Diseases, 2017.05.
3. Shuntaro Yamashita, Yoshinori Katakura, Screening and functional evaluation of food components that promote hair growth, Keystone Symposia Aging and Mechanisms of Aging-related Diseases, 2017.05.
4. Yoshinori Katakura, Mikako Sato, Yuka Sugihara, Carnosine activates the secretion of exosome form intestinal cells that activates neuronal cells, Keystone Symposia Aging and Mechanisms of Aging-related Diseases, 2017.05.
5. Chisato Kubo, Yoshinori Katakura, Screening and functional evaluation of food components that promote hair growth, JAACT2016 Kobe, 2016.11.
6. Saki Matsuoka, Yoshinori Katakura, Kosuke Fujita, Screening and functional evaluation of SIRT6-activating foods, JAACT2016 Kobe, 2016.11.
7. 片倉 喜範, 山下俊太郎, 小熊一郎, Thermo-responsive chromatography resin, Bioprocess International Europe, 2013.04.
8. 片倉 喜範, 山下 俊太郎, 小熊 一郎, 佐藤 聡, 奧山 和雄, Novel purification method of human antibody using a temperature-responsive protein A column, The 25th Annual and International Meeting of the Japanese Association for Animal Cell Technology, 2012.11.
9. 片倉 喜範, 藤井 薫, 門岡 桂史, 松本 貴之, 森松 文毅, Molecular basis for the carnosine-induced transcriptional activation of BDNF gene in Caco-2 cells., The 25th Annual and International Meeting of the Japanese Association for Animal Cell Technology, 2012.11.
10. 片倉 喜範, 原田 額郎, 松本 貴之, 森松 文毅, Pawat Pattarawat, 伊藤 謙二, Identification and functional evaluation of lactic acid bacteria that activates SIRT1 expression, Keystone Symposia Aging and Desease of Aging, 2012.10.
11. 片倉 喜範, 門岡 桂史, 松本 貴之, 森松 文毅, Carnosine induces Caco-2 cells to secrete neurotrophic factors and activate SH-SY5Y cells, Keystone Symposia Aging and Desease of Aging, 2012.10.
12. 片倉 喜範, 鵜殿 美弥子, Functional involvement of senescence-associated gene in the formation of Golgi apparatus, Keystone Symposia Aging and Desease of Aging, 2012.10.
13. 片倉 喜範, 山下 俊太郎, 小川 香織, Molecular mechanisms for FOXO3a-induced transcriptional activation of hTERT, Keystone Symposia Aging and Desease of Aging, 2012.10.
Membership in Academic Society
  • Japanese Society of Nutrition and Food Science
  • Japanese Society of Anti-aging Medicine
  • Japna Society of Bioscience, Biotechnology and Agrochemistry
  • Japanese Association for Animal Cell Technology
  • Molecular Biology Society of Japan
  • Japanese Association for Food Immunology
  • Japanese Society for Immunology
Educational
Educational Activities
Undergraduate School
Physical Chemistry, Physical Chemistry Experiment, Fundamental microorganism experiment

Graduate School
[Master course]
Systems Biological Chemistry, Cellular Functional Technology
Anti-aging food Technology

[Common University's education]
Molecular and Cellular Biology, Basic Biology
Social
Professional and Outreach Activities
1. Member of a committee "Basic survey of a novel technology relating to regulating mechanisms of cellular senescence, proliferation, and differentiation."
2. Science and Technology Experts Network Investigator
3. Lecture at Bioinformatics Summer School
4. Lecture at Mini-Genome Forum
5. Supervisor at Bioinformatics Summer School (2008)
6. Supervisor at Bioinformatics Summer School (2009).