| 1. |
Hiroyuki Hamada, Tadashi Tomo, Sung-Teh Kim, Akihiro C Yamashita, The Impact of Potassium Dynamics on Cardiomyocyte Beating in Hemodialysis Treatment, Journal of Clinical Medicine, https://doi.org/10.3390/jcm13082289, 13, 2289, 14pages, 2024.04.  |
| 2. |
濱田浩幸, 友雅司, 金成泰, 山下明泰, 血液浄化分野におけるデジタルトランスフォーメーションと人工知能, 日本血液浄化技術学会雑誌, 31, 2, 329-331, 2024.01. |
| 3. |
濱田浩幸, 野里蒼天, 田代康介, 友雅司, 金成泰, 山下明泰, 人工知能AIの必要性と導入要領：腎臓内科学と血液浄化領域へのAIの普及をめざして, 医工学治療, 35, 3, 173-177, 2023.11. |
| 4. |
Hiroyuki Hamada, Tadashi Tomo, Sung-Teh Kim, Taizo Hanai, Masahiro Okamoto, Akihiro C. Yamashita, 論文賞受賞レポート：Electrophysiological insights into the relationship between calcium dynamics and cardiomyocyte beating function in chronic hemodialysis treatment, 人工臓器, 52, 1, 29-31, 2023.06. |
| 5. |
濱田浩幸, 友雅司, 金成泰, 山下明泰, 血液透析治療中の心筋拍動能を評価する深層学習モデルの試作, 日本腎・血液浄化AI学会誌, 1, 1, 31-34, 2023.03. |
| 6. |
濱田 浩幸, 友雅司, 山下 明泰, 優秀演題賞報告：併用療法のカリウム動態が心筋細胞拍動能におよぼす影響, 腎と透析 腹膜透析, Vol.91, pp.47-49, 2021.09. |
| 7. |
Tatsuya Sekiguchi, Hiroyuki Hamada, Masahiro Okamoto, WinBEST-KIT: Biochemical Reaction Simulator for Analyzing Multi-Layered Metabolic Pathways, Bioengineering, https://doi.org/10.3390/bioengineering8080114, 8, 8, 114 (18 pages), 2021.08. |
| 8. |
Hiroyuki Hamada, Tadashi Tomo, Sung-Teh Kim, Taizo Hanai, Masahiro Okamoto, Akihiro C. Yamashita, Electrophysiological insights into the relationship between calcium dynamics and cardiomyocyte beating function in chronic hemodialysis treatment, Journal of Artificial Organs, DOI: 10.1007/s10047-020-01207-7, 24, 1, 58-64, 2021.03. |
| 9. |
濱田 浩幸, 友雅司, 金成泰, 山下 明泰, 慢性血液透析治療中の心筋細胞拍動能の数理解析, 人工臓器, https://doi.org/10.11392/jsao.49.199, 49, 3, 199-202, 2020.12. |
| 10. |
Hiroyuki Hamada, Satoshi Kurinomaru, Shogo Ohitokata, Yakun Yang, Kenta Asamura, Mari Deguchi, Yohei Motomura, Akiyuki Iwasaki, Tatsuya Sekiguchi, Taizo Hanai, Masahiro Okamoto, Mathematical analysis-based feasibility study of pre-emptive medicine for Staphylococcus aureus infectious disease: Early detection and antibiotic-free maintenance therapy, BioSystems, https://doi.org/10.1016/j.biosystems.2020.104238, 198, 1-8, 2020.12. |
| 11. |
濱田 浩幸, 友雅司, 山下 明泰, キネティックモデルを用いた腹膜透析患者の心機能評価, 腎と透析 腹膜透析, Vol.89, pp.27-29, 2020.09. |
| 12. |
狩野 智一, 鈴木崇人, 濱田 浩幸, 山下 明泰, 腹膜機能評価法における腹膜機能解析専用ソフトウェアの使用方法, 腎と透析 腹膜透析, Vol.89, pp.30-31, 2020.09. |
| 13. |
Tatsuya Sekiguchi, Hiroyuki Hamada, Masahiro Okamoto, WinBEST-KIT: Biochemical reaction simulator that can define and customize algebraic equations and events as GUI components, Journal of Bioinformatics and Computational Biology, https://doi.org/10.1142/S0219720019500367, 17, 6, 1950036 (22 pages), 2020.02. |
| 14. |
Hiroshi Honjo, Kenshiro Iwasaki, Yuki Soma, Keigo Tsuruno, Hiroyuki Hamada, Taizo Hanai, Synthetic microbial consortium with specific roles designated by genetic circuits for cooperative chemical production, Metabolic Engineering, https://doi.org/10.1016/j.ymben.2019.08.007, 55, 268-275, 2019.08. |
| 15. |
Tatsuya Sekiguchi, Hiroyuki Hamada, Masahiro Okamoto, Inference of General Mass Action-based State Equations for Oscillatory Biochemical Reaction Systems Using k-step Genetic Programming, Applied Mathematics, https://doi.org/10.4236/am.2019.108045, 10, 8, 627-645, 2019.08. |
| 16. |
Ryoichi Sakiyama, Hiroyuki Hamada, Brandon Blau, Nora Freyer, Katrin Zeilinger, Frank Schubert, Toshio Miki, Evaluation of the mass transfer rate using computer simulation in a three-dimensional interwoven hollow fiber-type bioartificial liver, Biotechnology Letters, https://doi.org/10.1007/s10529-018-2609-1, pp.1-12, 2018.09. |
| 17. |
Yasutaka Hirokawa, Shingo Matsuo, Hiroyuki Hamada, Fumio Matsuda, Taizo Hanai, Metabolic engineering of Synechococcus elongatus PCC 7942 for improvement of 1,3-propanediol and glycerol production based on in silico simulation of metabolic flux distribution, Microbial Cell Factories, https://doi.org/10.1186/s12934-017-0824-4, 16(1), 212, pp.1-12, 2017.11. |
| 18. |
Yohei Motomura, Hiroyuki Hamada, Masahiro Okamoto, An Effective Numerical Calculation Method for Multi Time-Scale Mathematical Models in Systems Biology, Applied Mathematics, http://dx.doi.org/10.4236/am.2016.717178, 7, 17, 2241-2268, 2016.11. |
| 19. |
濱田 浩幸, JSAO Grant 技術賞 論文賞報告：心筋拍動能が安定な血液透析治療システム実現のための数理的解析基盤の構築, 人工臓器, 45, 1, 33-34, 2016.07. |
| 20. |
成瀬 裕紀, 濱田 浩幸, 花井 泰三, 伊庭 斉志, 進化計算を用いた遺伝子回路設計, 生物工学会誌, 94, 185-189, 2016.03. |
| 21. |
Yuki Naruse, Hiroyuki Hamada, Taizo Hanai, Hitoshi Iba, Evolutionary design of oscillatory genetic networks in silico, Evolutionary Computation (IEEE CEC), , 17, 1596-1603, 2015.05. |
| 22. |
Kazunari Iwamoto, Hiroyuki Hamada, Yukihiro Eguchi, Masahiro Okamoto, Stochasticity of Intranuclear Biochemical Reaction Processes Controls the Final Decision of Cell Fate Associated with DNA Damage, PLOS ONE, doi:10.1371/journal.pone.0101333, 9, e101333, 2014.07. |
| 23. |
狩野 智一, 濱田 浩幸, 山下 明泰, 前田 裕之, 佐藤 雅文, 低浸透圧PD液でもできる簡易腹膜平衡試験, 腎と透析 腹膜透析, Vol.75, pp.255-256, 2013.08. |
| 24. |
Hiroyuki Hamada, Fumimasa Nomura, Tomoyuki Kaneko, Kenji Yasuda, and Masahiro Okamoto, Exploring the implicit interlayer regulatory mechanism between cells and tissue: Stochastic mathematical analyses of the spontaneous ordering in beating synchronization, BioSystems, 10.1016/j.biosystems.2013.02.007, , 111, 208-215, 2013.03. |
| 25. |
狩野智一・濱田浩幸・山下明泰・熊崎雅彦・名本真二, 残存腎機能（RRF） and 腹膜透析（PD） and/or 血液透析（HD） における透析量と栄養指標の比較, 腎と透析 腹膜透析, Vol.73, pp.249-250, 2012.10. |
| 26. |
Kazunari Iwamoto, Hiroyuki Hamada and Masahiro Okamoto , Mechanism of cell cycle disruption by multiple p53 pulses , Genome Informatics , 25, 1, 12-24, 2011.04. |
| 27. |
Kazunari Iwamoto, Hiroyuki Hamada, Yukihiro Eguchi and Masahiro Okamoto , Mathematical modeling of cell cycle regulation in response to DNA damage: exploring mechanisms of cell-fate determination , Biosystems , 103, , 384-391, 2011.01. |
| 28. |
狩野智一・濱田浩幸・石崎允・山下明泰・名本真二・山田亮, 透析量解析ソフトウェア"NAVI Light" ： 臨床における有用性と処方提案の考え方, 腎と透析 腹膜透析, Vol.69, pp.464-469, 2010.11. |
| 29. |
Hiroyuki Hamada, Atsushi Tada, Kazunari Iwamoto, Masahiro Okamoto, Numerical simulation for synchronization of excitatory action between beating cells , International Federation for Medical and Biological Engineering, 25, Vol.25, pp.1857-1860, 2009.10. |
| 30. |
Hiroyuki Hamada, Tomokazu Karino, Shinji Namoto, Akihiro C Yamashita, Makoto Ishizaki, Masahiro Okamoto, Development of Computer-Aided Diagnostic System for Peritoneal Dialysis: NAVI Light(TM), International Federation for Medical and Biological Engineering, Vol.25, 1818-1821, 2009.09. |
| 31. |
Hiroyuki Hamada, Yoshihiko Tashima, Yu Kisaka, Kazunari Iwamoto, Taizo Hanai, Yukihiro Eguchi, Masahiro Okamoto, Sophisticated framework between cell cycle arrest and apoptosis induction based on p53 dynamics, PLoS ONE, Vol.4, e4795, doi:10.1371/journal.pone.0004795, 2009.04. |
| 32. |
Koji Ishii, Hiroyuki Hamada, Masahiro Okamoto, Mathematical modeling for spatiotemporal development of leaf primordium, Proc. of the International Conference on Complex, Intelligent and Software Intensive Systems (IIBM 2009), 813-818, 2009.03. |
| 33. |
Koji Ishii, Hiroyuki Hamada, Masahiro Okamoto, Mathematical modeling for morphogenesis of leaf with employing cell automata and reaction-diffusion equation, Proc. of the Fourteenth International Symposium on Artificial Life and Robotics (AROB), Vol.14, pp.456-459, 2009.02. |
| 34. |
Kazunari Iwamoto, Yoshihiko Tashima, Hiroyuki Hamada, Yukihiro Eguchi, and Masahiro Okamoto, Blind spot of G1/S checkpoint: G1/S checkpoint is invaded by DNA-damage after R-point, Proc. of the IASTED International Symposium on Computational Biology and Bioinformatics (CBB), Vol.3, pp.241-246, 2008.11. |
| 35. |
Kazunari Iwamoto, Yoshihiko Tashima, Hiroyuki Hamada, Yukihiro Eguchi, Masahiro Okamoto, Mathematical modeling and Sensitivity analysis of G1/S phase in the cell cycle including the DNA damage signal transduction pathway, Biosystems, Vol.94(1), pp.109-117 , 2008.11. |
| 36. |
Yoshihiko Tashima, 濱田 浩幸, Masahiro Okamoto, Taizo Hanai, Prediction of key factor controlling G1/S phase in the mammalian cell cycle using system analysis, Journal of Bioscience and Bioengineering, Vol.106(4), pp.368-374, 2008.10. |
| 37. |
AA. Mamun, Hiroyuki Hamada, Tomokazu Karino, Shinji Namoto, Akihiro C. Yamashita, Makoto Ishizaki, Masahiro Okamoto, Clinical Application of Computer-Aided Diagnostic System for Harmonious Introduction of Complementary Dialysis Therapy, The Open Biomedical Engineering Journal, Vol.2(1), pp.10-16, 2008.04. |
| 38. |
岩本一成・田島慶彦・濱田浩幸・江口至洋・小野功・岡本正宏, 細胞周期制御システムの数理モデル化とシステム解析, 第35回知能システムシンポジウム論文集, Vol.35, pp.49-54, 2008.03. |
| 39. |
Hiroyuki Hamada, Shinji Namoto, Ryo Yamada, Abdullah Al Mamun, Akihiro C. Yamashita, Makoto Ishizaki, Masahiro Okamoto, Development of a computer-aided diagnosis system for continuous peritoneal dialysis: an availability of the Simultaneous Numerical Optimization Technique for Kinetic Parameters in the Peritoneal Dialysis Model, Computers in Biology and Medicine, Vol.37(12), pp.1700-1708, 2007.11. |
| 40. |
濱田浩幸・AA. Mamun・狩野智一・名本真二・山下明泰・石崎允・岡本正宏, 腹膜機能評価指標MTACu/cの有用性, 腎と透析 腹膜透析, Vol.63, pp.142-145, 2007.11. |
| 41. |
Kazunari Iwamoto, Yoshihiko Tashima, Hiroyuki Hamada, Yukihiro Eguchi, Masahiro Okamoto, Mathematical modeling and Sensitivity analysis of G1/S phase in the cell cycle including the DNA damage signal transduction pathway, Proc. of the Seventh International Workshop on Information Processing in Cells and Tissues (IPCAT), Vol.7, pp.281-292, 2007.08. |
| 42. |
Yoshihiko Tashima, Yu Kisaka, Hiroyuki Hamada, Taizo Hanai, Yukihiro Eguchi, Masahiro Okamoto, Analysis for the Conflict between G2/M Phase Arrest in the Cell Cycle and Apoptosis Induction, Genome Inforamtics, Vol.17, pp.P011:1-2, 2006.12. |
| 43. |
Kazunari Iwamoto, Yoshihiko Tashima, Hiroyuki Hamada, Yukihiro Eguchi, Masahiro Okamoto, Mathematical Modeling of G1/S Phase in the Cell Cycle with Involoving the p53/Mdm2 Netwirk, Genome Inforamtics, Vol.17, pp.P009:1-2, 2006.12. |
| 44. |
狩野智一・濱田浩幸・石崎允・山下明泰・名本真二・山田亮, 腹膜透析と血液透析の併用療法における透析量解析ソフトウェア（ＰＨＤ ＮＡＶＩ）の提案, 腎と透析 腹膜透析2006, Vol.61, pp.224-227, 2006.09. |
| 45. |
Hiroyuki Hamada, Abdula A. Mamun, Tomokazu Karino, Shinji Namoto, Akihiro C. Yamashita, Makoto Ishizaki and Masahiro Okamoto, Availability of a Novel Criterion for Peritoneal Diffusive Selectivity on Peritoneal Dialysis, International Federation for Medical and Biological Engineering, Vol.14, pp.3074-3077,, 2006.08. |
| 46. |
Yoshihiko Tashima, Yu Kisaka, Taizo Hanai, Hiroyuki Hamada, Yukihiro Eguchi, Masahiro Okamoto, Mathematical modeling of G2/M phase in cell cycle with involving the p53/Mdm2 oscillation system, International Federation for Medical and Biological Engineering, Vol.14, pp.195-198, 2006.08. |
| 47. |
Taizo Hanai, Hiroyuki Hamada, Masahiro Okamoto, Applied Bioinformatics for DNA micro array data to Bioscience, Bioengineering and Medical Field, Journal of Bioscience and Bioengineering, Vol.101(5), pp.337-384., 2006.05. |
| 48. |
Hiroyuki Hamada, Shinji Namoto, Ryo Yamada, Makoto Ishizaki, Masahiro Okamoto, Computer aided diagnosis system for a new modality of the renal replacement therapy: An integrated approach combining both peritoneal dialysis and hemodialysis, Computers in Biology and Medicine, Vol.35(12), pp.845-861, 2005.12. |
| 49. |
石井幸治・濱田浩幸・岡本正宏, セルオートマトンと反応－拡散方程式を統合した葉の形態形成に関する数値モデルの構築, 形の科学シンポジウム論文集, Vol.20(1), pp.83-84, 2005.06. |
| 50. |
中山昌明・濱田浩幸・石崎允・川西秀樹・中本雅彦・山下明泰・名本真二, PD NAVIによる腹膜劣化評価−high transporterの腹膜機能の特徴について, 日本透析医学会誌, Vol.38(4), pp.279‐285, 2005.04. |
| 51. |
Yoshihiko Tashima, Taizo Hanai, Hiroyuki Hamada, Masahiro Okamoto, Simulation for detailed mathematical model of G1-to-S Cell Cycle Phase Transition, Genome Informatics, Vol.15, pp.P009:1-2, 2004.12. |
| 52. |
Yoshihiko Tashima, Hiroyuki Hamada, Taizo Hanai, Masahiro Okamoto, System analysis for mathematical model of G1-to-S cell cycle phase transition, APCChE, Vol.10, pp.P436:1-6, 2004.10. |
| 53. |
Makoto Ishizaki, Akihiro C. Yamashita, Hideki Kawanishi, Masahiko Nakamoto, Hiroyuki Hamada, Dialysis Dose and Nutrition in Japanese Peritoneal Dialysis Patients, Advances in Peritoneal Dialysis, Vol.20, pp.141-144, 2004.09. |
| 54. |
Yoshihiko Tashima, Taizo Hanai, Hiroyuki Hamada, Masahiro Okamoto, Kinetics Behavior of G1-to-S Cell Cycle Phase Transition Model, Genome Informatics, Vol.14, pp.607-608, 2003.12. |
| 55. |
Akihiro C. Yamashita, Makoto Ishizaki, Masahiko Nakamoto, Hideki Kawanishi, Hiroyuki Hamada, Re-evaluation of adequate dose in Japanese PD patients, Advances in Peritoneal Dialysis, Advances in Peritoneal Dialysis, Vol.19, pp.103-106, 2003.09. |
| 56. |
吉村茂晴・濱田浩幸・山田亮・山下明泰, 内部濾過促進型ダイアライザー開発の理論的アプローチ, 腎と透析別冊：HDF療法’02, Vol.2002, pp.46-48, 2002.05. |
| 57. |
Hiroyuki Hamada, Ryoichi Sakiyama, Akihiro C. Yamashita, Masahiro Okamoto, Kakuji J. Tojo, Kazuo Kumano and Tadasu Sakai, Validation of New Analytical Solution for Pyle-Popovich’s Peritoneal Dialysis Model, Nephrology, Vol.5(1), pp.59-64, 2000.05. |
| 58. |
Hiroyuki Hamada, Ryoichi Sakiyama, Akihiro C. Yamashita, Masahiro Okamoto and Kakuji J. Tojo, New Analytical Solution for Pyle-Popovich’s Peritoneal Dialysis Model, Journal of Chemical Engineering of Japan, Vol.32, pp.498-505, 1999.11. |
| 59. |
濱田浩幸・崎山亮一・山下明泰, 透析液量と体液量の比を用いたPET-D/D0曲線の適用法, 腹膜透析, Vol.4, pp.221-223, 1999.09. |
| 60. |
濱田浩幸・崎山亮一・山下明泰, 総括物質移動・膜面積係数の簡易的算出法の比較, 腹膜透析, Vol.3, pp.170-171, 1998.09. |
| 61. |
Hiroyuki Hamada, Tuyoshi Kobayashi, Katuya Hayashi, Masahiro Okamoto, Pace making mechanism of excitatory wave propagation in excitation conducting system, 13th International Congress of Chemical and Process Engineering Summaries 3 Symposium on Non-linear Dynamics in Chemical and Bioengineering Processes, Vol.13(C2), pp.4-12, 1998.08. |
| 62. |
山下明泰・濱田浩幸, 腹膜透過能の新しい簡易評価式の導出, 日本透析医学会誌, Vol.31(3), pp.183～189, 1998.03. |
| 63. |
山下明泰・崎山亮一・濱田浩幸・東條角治, 篩係数の２つの新しい定義式, ハイパフォーマンスメンブレン, Vol.98, pp.36-38, 1998.01. |
| 64. |
Akihiro C. Yamashita, Ryoichi Sakiyama, Hiroyuki Hamada, Kakuji J. Tojo, Control of Rate of Solution Transport in Newly Developed Novel Portable Agar Gel Blood Purification System, Home Hemodialysis International, Vol.2(1), pp.67-70, 1998.01. |
| 65. |
濱田浩幸・岡本正宏, 刺激伝導系における興奮の伝播のコンピュータシミュレーション, 生体・生理工学シンポジウム論文集, Vol.9, pp.351-354, 1994.11. |
