| 1. |
Hiroyuki Hamada, Tadashi Tomo, Sung-Teh Kim, Akihiro C Yamashita, The Impact of Potassium Dynamics on Cardiomyocyte Beating in Hemodialysis Treatment, Journal of Clinical Medicine, https://doi.org/10.3390/jcm13082289, 13, 2289, 14pages, 2024.04. |
| 2. |
Hiroyuki Hamada, Tadashi Tomo, Sung-Teh Kim, Taizo Hanai, Masahiro Okamoto, Akihiro C. Yamashita, 論文賞受賞レポート：Electrophysiological insights into the relationship between calcium dynamics and cardiomyocyte beating function in chronic hemodialysis treatment, 人工臓器, 52, 1, 29-31, 2023.06. |
| 3. |
濱田浩幸, 友雅司, 金成泰, 山下明泰, 血液透析治療中の心筋拍動能を評価する深層学習モデルの試作, 日本腎・血液浄化AI学会誌, 1, 1, 31-34, 2023.03. |
| 4. |
Tatsuya Sekiguchi, Hiroyuki Hamada, Masahiro Okamoto, WinBEST-KIT: Biochemical Reaction Simulator for Analyzing Multi-Layered Metabolic Pathways, Bioengineering, https://doi.org/10.3390/bioengineering8080114, 8, 8, 114 (18 pages), 2021.08. |
| 5. |
Hiroyuki Hamada, Tadashi Tomo, Sung-Teh Kim, Taizo Hanai, Masahiro Okamoto, Akihiro C. Yamashita, Electrophysiological insights into the relationship between calcium dynamics and cardiomyocyte beating function in chronic hemodialysis treatment, Journal of Artificial Organs, DOI: 10.1007/s10047-020-01207-7, 24, 1, 58-64, 2021.03. |
| 6. |
Hiroyuki Hamada, Satoshi Kurinomaru, Shogo Ohitokata, Yakun Yang, Kenta Asamura, Mari Deguchi, Yohei Motomura, Akiyuki Iwasaki, Tatsuya Sekiguchi, Taizo Hanai, Masahiro Okamoto, Mathematical analysis-based feasibility study of pre-emptive medicine for Staphylococcus aureus infectious disease: Early detection and antibiotic-free maintenance therapy, BioSystems, https://doi.org/10.1016/j.biosystems.2020.104238, 198, 1-8, 2020.12. |
| 7. |
Tatsuya Sekiguchi, Hiroyuki Hamada, Masahiro Okamoto, WinBEST-KIT: Biochemical reaction simulator that can define and customize algebraic equations and events as GUI components, Journal of Bioinformatics and Computational Biology, https://doi.org/10.1142/S0219720019500367, 17, 6, 1950036 (22 pages), 2020.02. |
| 8. |
Hiroshi Honjo, Kenshiro Iwasaki, Yuki Soma, Keigo Tsuruno, Hiroyuki Hamada, Taizo Hanai, Synthetic microbial consortium with specific roles designated by genetic circuits for cooperative chemical production, Metabolic Engineering, https://doi.org/10.1016/j.ymben.2019.08.007, 55, 268-275, 2019.08. |
| 9. |
Tatsuya Sekiguchi, Hiroyuki Hamada, Masahiro Okamoto, Inference of General Mass Action-based State Equations for Oscillatory Biochemical Reaction Systems Using k-step Genetic Programming, Applied Mathematics, https://doi.org/10.4236/am.2019.108045, 10, 8, 627-645, 2019.08. |
| 10. |
Ryoichi Sakiyama, Hiroyuki Hamada, Brandon Blau, Nora Freyer, Katrin Zeilinger, Frank Schubert, Toshio Miki, Evaluation of the mass transfer rate using computer simulation in a three-dimensional interwoven hollow fiber-type bioartificial liver, Biotechnology Letters, https://doi.org/10.1007/s10529-018-2609-1, pp.1-12, 2018.09. |
| 11. |
Yasutaka Hirokawa, Shingo Matsuo, Hiroyuki Hamada, Fumio Matsuda, Taizo Hanai, Metabolic engineering of Synechococcus elongatus PCC 7942 for improvement of 1,3-propanediol and glycerol production based on in silico simulation of metabolic flux distribution, Microbial Cell Factories, https://doi.org/10.1186/s12934-017-0824-4, 16(1), 212, pp.1-12, 2017.11. |
| 12. |
Yohei Motomura, Hiroyuki Hamada, Masahiro Okamoto, An Effective Numerical Calculation Method for Multi Time-Scale Mathematical Models in Systems Biology, Applied Mathematics, http://dx.doi.org/10.4236/am.2016.717178, 7, 17, 2241-2268, 2016.11. |
| 13. |
Yuki Naruse, Hiroyuki Hamada, Taizo Hanai, Hitoshi Iba, Evolutionary design of oscillatory genetic networks in silico, Evolutionary Computation (IEEE CEC), , 17, 1596-1603, 2015.05. |
| 14. |
Kazunari Iwamoto, Hiroyuki Hamada, Yukihiro Eguchi, Masahiro Okamoto, Stochasticity of Intranuclear Biochemical Reaction Processes Controls the Final Decision of Cell Fate Associated with DNA Damage, PLOS ONE, doi:10.1371/journal.pone.0101333, 9, e101333, 2014.07. |
| 15. |
Hiroyuki Hamada, Fumimasa Nomura, Tomoyuki Kaneko, Kenji Yasuda, and Masahiro Okamoto, Exploring the implicit interlayer regulatory mechanism between cells and tissue: Stochastic mathematical analyses of the spontaneous ordering in beating synchronization, BioSystems, 10.1016/j.biosystems.2013.02.007, , 111, 208-215, 2013.03. |
| 16. |
Kazunari Iwamoto, Hiroyuki Hamada and Masahiro Okamoto , Mechanism of cell cycle disruption by multiple p53 pulses , Genome Informatics , 25, 1, 12-24, 2011.04. |
| 17. |
Kazunari Iwamoto, Hiroyuki Hamada, Yukihiro Eguchi and Masahiro Okamoto , Mathematical modeling of cell cycle regulation in response to DNA damage: exploring mechanisms of cell-fate determination , Biosystems , 103, , 384-391, 2011.01. |
| 18. |
Hiroyuki Hamada, Atsushi Tada, Kazunari Iwamoto, Masahiro Okamoto, Numerical simulation for synchronization of excitatory action between beating cells , International Federation for Medical and Biological Engineering, 25, Vol.25, pp.1857-1860, 2009.10. |
| 19. |
Hiroyuki Hamada, Tomokazu Karino, Shinji Namoto, Akihiro C Yamashita, Makoto Ishizaki, Masahiro Okamoto, Development of Computer-Aided Diagnostic System for Peritoneal Dialysis: NAVI Light(TM), International Federation for Medical and Biological Engineering, Vol.25, 1818-1821, 2009.09. |
| 20. |
Hiroyuki Hamada, Yoshihiko Tashima, Yu Kisaka, Kazunari Iwamoto, Taizo Hanai, Yukihiro Eguchi, Masahiro Okamoto, Sophisticated framework between cell cycle arrest and apoptosis induction based on p53 dynamics, PLoS ONE, Vol.4, e4795, doi:10.1371/journal.pone.0004795, 2009.04. |
| 21. |
Koji Ishii, Hiroyuki Hamada, Masahiro Okamoto, Mathematical modeling for spatiotemporal development of leaf primordium, Proc. of the International Conference on Complex, Intelligent and Software Intensive Systems (IIBM 2009), 813-818, 2009.03. |
| 22. |
Koji Ishii, Hiroyuki Hamada, Masahiro Okamoto, Mathematical modeling for morphogenesis of leaf with employing cell automata and reaction-diffusion equation, Proc. of the Fourteenth International Symposium on Artificial Life and Robotics (AROB), Vol.14, pp.456-459, 2009.02. |
| 23. |
Kazunari Iwamoto, Yoshihiko Tashima, Hiroyuki Hamada, Yukihiro Eguchi, and Masahiro Okamoto, Blind spot of G1/S checkpoint: G1/S checkpoint is invaded by DNA-damage after R-point, Proc. of the IASTED International Symposium on Computational Biology and Bioinformatics (CBB), Vol.3, pp.241-246, 2008.11. |
| 24. |
Kazunari Iwamoto, Yoshihiko Tashima, Hiroyuki Hamada, Yukihiro Eguchi, Masahiro Okamoto, Mathematical modeling and Sensitivity analysis of G1/S phase in the cell cycle including the DNA damage signal transduction pathway, Biosystems, Vol.94(1), pp.109-117 , 2008.11. |
| 25. |
Yoshihiko Tashima, 濱田 浩幸, Masahiro Okamoto, Taizo Hanai, Prediction of key factor controlling G1/S phase in the mammalian cell cycle using system analysis, Journal of Bioscience and Bioengineering, Vol.106(4), pp.368-374, 2008.10. |
| 26. |
AA. Mamun, Hiroyuki Hamada, Tomokazu Karino, Shinji Namoto, Akihiro C. Yamashita, Makoto Ishizaki, Masahiro Okamoto, Clinical Application of Computer-Aided Diagnostic System for Harmonious Introduction of Complementary Dialysis Therapy, The Open Biomedical Engineering Journal, Vol.2(1), pp.10-16, 2008.04. |
| 27. |
Hiroyuki Hamada, Shinji Namoto, Ryo Yamada, Abdullah Al Mamun, Akihiro C. Yamashita, Makoto Ishizaki, Masahiro Okamoto, Development of a computer-aided diagnosis system for continuous peritoneal dialysis: an availability of the Simultaneous Numerical Optimization Technique for Kinetic Parameters in the Peritoneal Dialysis Model, Computers in Biology and Medicine, Vol.37(12), pp.1700-1708, 2007.11. |
| 28. |
Kazunari Iwamoto, Yoshihiko Tashima, Hiroyuki Hamada, Yukihiro Eguchi, Masahiro Okamoto, Mathematical modeling and Sensitivity analysis of G1/S phase in the cell cycle including the DNA damage signal transduction pathway, Proc. of the Seventh International Workshop on Information Processing in Cells and Tissues (IPCAT), Vol.7, pp.281-292, 2007.08. |
| 29. |
Yoshihiko Tashima, Yu Kisaka, Hiroyuki Hamada, Taizo Hanai, Yukihiro Eguchi, Masahiro Okamoto, Analysis for the Conflict between G2/M Phase Arrest in the Cell Cycle and Apoptosis Induction, Genome Inforamtics, Vol.17, pp.P011:1-2, 2006.12. |
| 30. |
Kazunari Iwamoto, Yoshihiko Tashima, Hiroyuki Hamada, Yukihiro Eguchi, Masahiro Okamoto, Mathematical Modeling of G1/S Phase in the Cell Cycle with Involoving the p53/Mdm2 Netwirk, Genome Inforamtics, Vol.17, pp.P009:1-2, 2006.12. |
| 31. |
Hiroyuki Hamada, Abdula A. Mamun, Tomokazu Karino, Shinji Namoto, Akihiro C. Yamashita, Makoto Ishizaki and Masahiro Okamoto, Availability of a Novel Criterion for Peritoneal Diffusive Selectivity on Peritoneal Dialysis, International Federation for Medical and Biological Engineering, Vol.14, pp.3074-3077,, 2006.08. |
| 32. |
Yoshihiko Tashima, Yu Kisaka, Taizo Hanai, Hiroyuki Hamada, Yukihiro Eguchi, Masahiro Okamoto, Mathematical modeling of G2/M phase in cell cycle with involving the p53/Mdm2 oscillation system, International Federation for Medical and Biological Engineering, Vol.14, pp.195-198, 2006.08. |
| 33. |
Taizo Hanai, Hiroyuki Hamada, Masahiro Okamoto, Applied Bioinformatics for DNA micro array data to Bioscience, Bioengineering and Medical Field, Journal of Bioscience and Bioengineering, Vol.101(5), pp.337-384., 2006.05. |
| 34. |
Hiroyuki Hamada, Shinji Namoto, Ryo Yamada, Makoto Ishizaki, Masahiro Okamoto, Computer aided diagnosis system for a new modality of the renal replacement therapy: An integrated approach combining both peritoneal dialysis and hemodialysis, Computers in Biology and Medicine, Vol.35(12), pp.845-861, 2005.12. |
| 35. |
Evaluation of peritoneal damage by PD NAVI-characteristics of high transporter. |
| 36. |
Yoshihiko Tashima, Taizo Hanai, Hiroyuki Hamada, Masahiro Okamoto, Simulation for detailed mathematical model of G1-to-S Cell Cycle Phase Transition, Genome Informatics, Vol.15, pp.P009:1-2, 2004.12. |
| 37. |
Yoshihiko Tashima, Hiroyuki Hamada, Taizo Hanai, Masahiro Okamoto, System analysis for mathematical model of G1-to-S cell cycle phase transition, APCChE, Vol.10, pp.P436:1-6, 2004.10. |
| 38. |
Makoto Ishizaki, Akihiro C. Yamashita, Hideki Kawanishi, Masahiko Nakamoto, Hiroyuki Hamada, Dialysis Dose and Nutrition in Japanese Peritoneal Dialysis Patients, Advances in Peritoneal Dialysis, Vol.20, pp.141-144, 2004.09. |
| 39. |
Yoshihiko Tashima, Taizo Hanai, Hiroyuki Hamada, Masahiro Okamoto, Kinetics Behavior of G1-to-S Cell Cycle Phase Transition Model, Genome Informatics, Vol.14, pp.607-608, 2003.12. |
| 40. |
Akihiro C. Yamashita, Makoto Ishizaki, Masahiko Nakamoto, Hideki Kawanishi, Hiroyuki Hamada, Re-evaluation of adequate dose in Japanese PD patients, Advances in Peritoneal Dialysis, Advances in Peritoneal Dialysis, Vol.19, pp.103-106, 2003.09. |
| 41. |
Hiroyuki Hamada, Ryoichi Sakiyama, Akihiro C. Yamashita, Masahiro Okamoto, Kakuji J. Tojo, Kazuo Kumano and Tadasu Sakai, Validation of New Analytical Solution for Pyle-Popovich’s Peritoneal Dialysis Model, Nephrology, Vol.5(1), pp.59-64, 2000.05. |
| 42. |
Hiroyuki Hamada, Ryoichi Sakiyama, Akihiro C. Yamashita, Masahiro Okamoto and Kakuji J. Tojo, New Analytical Solution for Pyle-Popovich’s Peritoneal Dialysis Model, Journal of Chemical Engineering of Japan, Vol.32, pp.498-505, 1999.11. |
| 43. |
Availablitiy of PET-D/DO curve considering the ratio of Infusion dialysate volume to Total Body Fluid volume. |
| 44. |
Availablitiy of simle approximated analytical solution for MTAC. |
| 45. |
Hiroyuki Hamada, Tuyoshi Kobayashi, Katuya Hayashi, Masahiro Okamoto, Pace making mechanism of excitatory wave propagation in excitation conducting system, 13th International Congress of Chemical and Process Engineering Summaries 3 Symposium on Non-linear Dynamics in Chemical and Bioengineering Processes, Vol.13(C2), pp.4-12, 1998.08. |
| 46. |
Akihiro C. Yamashita, Ryoichi Sakiyama, Hiroyuki Hamada, Kakuji J. Tojo, Control of Rate of Solution Transport in Newly Developed Novel Portable Agar Gel Blood Purification System, Home Hemodialysis International, Vol.2(1), pp.67-70, 1998.01. |
