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Mitsugu Todo Last modified date:2018.07.12



Graduate School


E-Mail
Homepage
http://www.riam.kyushu-u.ac.jp/ece/index-e.htm
I perform reserach works and education of graduate students on bioengineering such as biomechanics of artificial joints and mechanics of bioabsorbable materials. .
Phone
092-583-7762
Fax
092-583-7762
Academic Degree
Ph.D.
Field of Specialization
Tissue engineering/Biomechanics/Biomaterial
Outline Activities
The primary objective of my research work is to clarify the deformation, damage development and fracture behavior of advanced bio-composite systems and materials such as artificial joints and bioabsorbable materials. Experimental mechanics for macroscopic mechanical testing and microscopic analysis in addition to computational mechancis are utilized to perform my research works. The main topics of research are:
1. Development and evaluation of mechanical properties of bio-composite materials
2. Computational analysis of artificial joints
3. Development of porous biomaterials for regenerative medicine
4. Biomechanical analysis of the problems in orthopedics
5. Relationship between porous material and cell growth
Research
Research Interests
  • Analysis of strength reduction of bone due to osteoporosis
    keyword : FEM, CT, biomechanics, solid mechanics
    2016.04~2019.03.
  • Development of bio-pump using cardiomyocites derived from iPS cells
    keyword : tissue engineering, biomechanics, biomaterial
    2017.06~2019.03.
  • Devlopment and characterization of cell sheets using mesenchymal stem cells
    keyword : Regenerative medicine, Tissue engineering, Differentiation
    2013.10.
  • Development of bio fuel cell using porous nano composite materials
    keyword : biomaterial, medical device, new energy
    2012.04.
  • Development of composite porous baiomaterial with drug release function
    keyword : biomaterial, drug releae system, regenerative medicine
    2012.01.
  • Study on proliferation behavior of stem cell using collagen scaffold
    keyword : stem cell, collagen scaffold
    2011.04.
  • Development and assessment of next generation artificial hip joints
    keyword : hip prosthesis, biomechanics, hip joint
    2009.03.
  • Development and characterization of bioabsorbable PLLApolymer blends
    keyword : Biomaterial, Bioabsorbability, Polymer blend, Fracture properties
    2004.03~2013.03.
  • Study on improvement of HA/PLLA composite materials
    keyword : Bioabsorbable materials, Bone fixation materials, Fracture properties
    2006.04~2013.03.
  • Stress analysis and development of jaw bone model with dental implants
    keyword : dental implant, biomechanics, FEM simulation
    2005.04~2013.03.
  • Development and fracture property evaluation of PLLA/PCL polymer blends
    keyword : polymer blends, PLLA, PCL, Fracture proeprties
    2002.04~2013.03.
Current and Past Project
  • Fabrication process of natural fiber reinforced thermoset composite materials (Green Composite) was investigated and the mechanical proerpties of the composites were characterized to develop an optimized fabrication process for this type of composite system.
Academic Activities
Books
1. MItsugu Todo, Tetsuo Takayama, Biomaterials - Physics and Chemistry -, Chapter 19 : Fracture mechanisms of biodegradable PLA and PLA/PCL blends, In Tech Co., 2011.10.
Reports
1. Mitsugu Todo, Mechanical Studies on Biomaterials for Reconstruction of Lower Limb Functions, 2010.05.
Papers
1. M.A. Mohd Afzan, M. Todo, R. Nagamie, S. Hirokawa, Effect of bearing mobility on the kinetics performance of TKA during deep flexion: A computational simulation, Applied Mechanics and Materials, 393, 899-906, 2013.10.
2. Todo Mitsugu, S. Hwang, Biomechanical effect of implantation of chitosan/MWNTs reinforced scaffold into damaged femur, Journal of Novel Carbon Resource Science, 7, 1-6, 2013.02.
3. Phanny YOS, Mitsugu TODO, Development and characterization of poly(-caprolactone) reinforced porous hydroxyapatite for bone tissue engineering, Key Engineering Materials, 529-530, 447-452, 2013.01.
4. Todo Mitsugu, Vilay Vannaladsaysy, Characterization of mode I fracture and morphological properties of PLLA blends with addition of lysine triisocyanate, Journal of Solid Mechanics and Materials Engineering, 6, 4, 314-422, 2012.11.
5. Todo Mitsugu, L.M. Ren, Takaaki Arahira, A comparative biomechanical study of bone ingrowth in two porous hydroxyapatite bioceramics, 81-88, 2012.08.
6. Li-Mei Ren, Takaaki Arahira, Mitsugu Todo, Hideki Yoshikawa and Akira Myoui, Biomechanical evaluation of porous bioactive ceramics after implantation: micro CT-based three-dimensional finite element analysis, Journal of Materials Science: Materials in Medicine, 23, 463-472, 2012.02.
7. J.E. Park and M. Todo, Compressive mechanical properties and deformation behavior of porous polymer blends of poly(e-caprolactone) and poly(L-lactic acid), Journal of Materials Science, 46, 7850-7858, 2011.10.
8. T. Takayama, M. Todo and H. Tsuji, Effect of annealing on the mechanical properties of PLA/PCL and PLA/PCL/LTI polymer blends, Journal of the Mechanical Behavior of Biomedical Materials, 4, 255-260, 2011.10.
9. J.E. Park and M. Todo, Development and characterization of reinforced poly(L-lactide) scaffolds for bone tissue Engineering, Journal of Materials Science: Materials in Medicine, 22, 1171-1182, 2011.08.
10. V. Vannaladsaysy, M.Todo, M. Jaafar, Z. Ahmad, Characterization of Microstructure and Mechanical Properties of Biodegradable Polymer Blends of Poly(L-lactic acid) and Poly(butylene succinate-co-ε-caprolactone) with Lysine triisocyanate, Polymer Engineering and Science, 2011.05.
11. L.M. Ren, M. Todo, T. Arahira, A. Myoui, Biomechanical interaction between porous bioactive ceramics and regenerated bone tissue, Proceedings of The 2nd International Conference on Nanomechanics & Nanocomposites, 258-261, 2010.10.
12. T. Arahira, M. Todo, Y. Matsushita, K. koyano, Assessment of Mechanical Stability and Safety for Fully Edentulous Maxilla with Dental Implants, Journal of Solid Mechanics and Materials Engineering, 5, 5, 526-538, 2010.08.
13. J.E. Park, M. Todo, Characterization of microstructure and compressive deformation behavior of reinforced porous poly(L-lactide), Advanced Materials Research, 123-125, 303-306, 2010.08.
14. J.E. Park and M. Todo, Development of layered porous poly(L-lactide) for bone regeneration, Journal of Materials Science, 45, 3966-3968, 2010.08.
15. T. Takayama, M. Todo, Improvement of Fracture Properties of Hydroxyapatite Particle Filled Poly(L-lactide)/Poly(e-caprolactone) Biocomposites using Lysine Tri-Isocyanate, Journal of Materials Science, 45, 22, 6266-6270, 2010.07.
16. L. Qian, M. Todo, Y. Matsushita, K. Koyano, Three-dimensional finite element analysis of overload-induced alveolar bone resorption around dental implants, Interface Oral Health Science 2009, 155-157, 2010.05.
17. V. Vilay, M. Mariatti, Zulkifli Ahmad, Mitsugu Todo, and K. Pasomsouk, Effect of Copolymer on the Mechanical and Thermal Properties and Morphological Behavior of Biodegradable Poly (L-lactic acid) (PLLA) and Poly (Butylene Succinate-co-L-Lactate) (PBSL) Blends, Polymers for Advanced Technologies, 2010.03.
18. Tetsuo Takayama and Mitsugu Todo, Improvement of Mechanical Properties of Hydroxyapatite Particle Filled Poly(L-lactide) Biocomposites using Lysine Tri-Isocyanate, Journal of Materials Science, 44, 18, 5017-5020, 2009.11.
19. Vilay Vannaladsaysy, Mitsugu Todo, Tetsuo Takayama, Mariatti Jaafar, Ahmad Zulkifli and Korakanh Pasomsouk, Effect of lysine triisocyanate on the mode I fracture behavior of polymer blend of poly(L-lactic acid) and poly(butylene succinate-co-L-lactide), Journal of Materials Science, 44, 11, 3006-3009, 2009.10.
20. Mitsugu Todo, Joo-Eon Park, Hiroyuki Kuraoka, Jin-Woong Kim, Kentaro Taki and Masahiro Ohshima, Compressive deformation behavior of porous PLLA/PCL polymer blend, Journal of Materials Science, 44, 15, 4191-4194, 2009.10.
21. Lihe Qian, Mitsugu Todo, Yasuyuki Morita, Yasuyuki Matsushita and Kiyoshi Koyano, Deformation analysis of the periodontium considering the viscoelasticity of the periodontal ligament, Dental Materials, 25, 1285-1292, 2009.10.
22. Lihe Qian, Mitsugu Todo, Yasuyuki Matsushita and Kiyoshi Koyano, Effects of implant diameter, insertion depth and loading angle on stress/strain fields in implant/jawbone system, The International Journal of Oral & Maxillofacial Implants, 24, 877-886, 2009.10.
23. Lihe Qian, Mitsugu Todo, Yasuyuki Matsushita and Kiyoshi Koyano, Finite Element Analysis of Bone Resorption around Dental Implant, Journal of Biomechanical Science and Engineering, 4, 3, 365-376, 2009.08.
24. Tetsuo Takayama, Mitsugu Todo and Atsushi Takano, The effect of bimodal distribution on the mechanical properties of hydroxyapatite particle filled poly(L-lactide) composites, Journal of the Mechanical Behavior of Biomedical Materials, 2, 105-112, 2009.05.
25. Tetsuo Takayama, Mitsugu Todo, Atsushi Takano, The effect of bimodal distribution on the mechanical properties of hydroxyapatite particle filled poly(L-lactide) composites, Journal of the Mechanical Behavior of Biomedical Materials, Vol.2, pp.105-112, 2008.10.
26. Mitsugu Todo, Yuji Takahashi, Ryuji Nagamine, Stress analysis of artificial knee joints under flexion and rotation, Tribology Online, 3, 3, 211-215, 2008.09.
27. Mitsugu Todo, Hiroyuki Kuraoka, Jinwoong Kim, Kentaro Taki, Masahiro Ohshima, Deformation behavior and mechanism of porous PLLA under compresion, Journal of Materials Science, Vol.43, No.16, pp.5644-5646, 2008.09.
28. M. Todo, T. Kagawa, Y. Takenoshita and A. Myoui, Effect of Press Processing on Fracture Behavior of HA/PLLA Biocomposite Material, Journal of Solid Mechanics and Materials Engineering, Vol.2, No.1, 1-7, 2008.04.
29. M. Todo, T. Takayama, H. Tsuji and K. Arakawa, Effect of LTI Blending on Fracture Proeprties of PLA/PCL Polymer Blend, Journal of Solid Mechanics and Materials Engineering , Vol.1, No.9, 1157-1164, 2007.10.
30. M. Todo, R. Nagamine and S. Yamaguchi, Stress Analysis of PS Type Knee Prostheses under Deep Flexion, Journal of Biomechanical Science and Engineering, Vol.2, No.4, 237-245, 2007.10.
31. M. Todo and T. Takayama, Toughening of bioabsorbable polymer blend by microstructural modification, Interface Oral Health Science 2007, 95-104, 2007.10.
32. M. Todo and T. Kagawa, Improvement of Fracture Energy of HA/PLLA Biocomposite Material due to Press Processing, Journal of Materials Science, Vol.43, 799-801, 2007.10.
33. M. Todo, S.D. Park, T. Takayama and K. Arakawa, Fracture micromechanisms of bioabsorbable PLLA/PCL polymer blends, Engineering Fracture Mechanics, Vol.74, 1872-1883., 2007.08.
34. S.-D. Park, M. Todo and K. Arakawa, Effect of Annealing on the Fracture Toughness of Poly(lactic acid), Journal of Materials Science, 10.1023/B:JMSC.0000012957.02434.1e, 39, 3, 1113-1116, Vol.39, pp.1113-1116, 2004.01.
35. S.D. Park, M. Todo and K. Arakawa, Effect of annealing on fracture mechanism of biodegradable poly(lactic acid), Key Engineering Materials, 261-263, 105-110, Vol.261-263, pp.105-110, 2004.01.
36. M. Todo, S. Komeda and K. Arakawa, Effect of Rubber Blending on the Fracture Behavior of Glass Microballoon Filled Epoxy Resin, Proceedings of the Third Japan-Korea Joint Symposium on Composite Materials, pp.75-76., 2002.10.
37. M. Todo, N. Shinohara and K. Arakawa, Effects of Crystallization and Loading-rate on the Mode I Fracture Toughness of Biodegradable Poly(lactic acid), Journal of Materials Science Letters, 10.1023/A:1016520518959, 21, 15, 1203-1206, Vol.21, pp.1203-1206, 2002.01.
38. M. Todo and K. Takahashi, Loading-Rate Dependence of Mode I Fracture Behavior of Rubber-Toughened PMMA, Proceedings of the 10th International Conference on Fracture, CD-ROM, 2001.12.
39. M. Todo and K. Takahashi, Displacement-Rate Dependence of the Bending Fracture Behavior of Interlayer-Toughened Carbon/Epoxy Composite, Materials Science Research International, Special Technical Publication-2, pp.266-270, 2001.01.
40. M. Todo, T. Nakamura and K. Takahashi, Effects of Moisture Absorption on the Dynamic Interlaminar Fracture Toughness of Carbon/Epoxy Composites, Journal of Composite Materials, 10.1106/UFBK-445F-NV22-BAPH, 34, 8, 630-648, Vol.34, No.8, pp.630-648, 2000.01.
41. M. Todo, K. Arakawa and K. Takahashi, Nonlinear Displacement Field in the Vicinity of Notch-Tip in Rubber Toughened PMMA, Key Engineering Materials, 183-1, 409-414, Vol.183-187, pp.409-414, 2000.01.
42. M. Todo, K. Takahashi, Ph. Beguelin and H.H. Kausch, Effect of Displacement Rate on the Mode I Fracture Behavior of Rubber Toughened PMMA, JSME International Journal, Series A, 42, 1, 49-56, Vol.42, No.1, pp.49-56, 1999.01.
43. M. Todo, K. Takahashi, P.-Y. Ben Jar and Ph. Beguelin, Toughening Mechanisms of Rubber Toughened PMMA, JSME International Journal, Series A, 42, 4, 585-591, Vol.42, No.4, pp.585-591., 1999.01.
44. M. Todo, T. Nakamura, T. Mada and K. Takahashi, Measurement of Dynamic Interlaminar Fracture Toughness of FRP Laminates Using Dynamic Displacement Measuring Apparatus, Advanced Composite Materials, 10.1163/156855198X00200, 7, 3, 285-297, Vol.7, No.3, pp.285-297, 1998.01.
Presentations
1. @Mitsugu Todo, Ikuho Yonezawa, Development of bone strength prediction method by using multidisciplinary computational anatomy with damage mechanics, Fourth International Symposium on the project “Multidisciplinary Computational Anatomy”, 2018.03.
2. P. Yos, Md. Abdul Kafi, M. Todo, Mechanical variation and proliferation behavior in hydroxyapatite based scaffolds with mesenchymal stem cells, The 15th International Conference on Biomedical Engineering, 2013.12.
3. M. Todo, N. Yamada, Development and characterization of bioceramic/polymer composite scaffold with drug release function for bone tissue engineering, The 15th International Conference on Biomedical Engineering, 2013.12.
4. M. Todo, K. Yamauchi, Development and characterization of CNT/biopolymer electrodes for bio-fuel cell, The 15th International Conference on Biomedical Engineering, 2013.12.
5. Md. Abdul Kafi, M. Todo, Proliferation behavior of mesenchymal stem cells in peptide functionalized chitosan scaffolds, The 15th International Conference on Biomedical Engineering, 2013.12.
6. U. Nakamuta, M. Todo, T. Arahira, Characterization of compressive mechanical behavior of gel/sponge 2-phase scaffold for cartilage tissue engineering, The 7th Asian Pasific Conference on Biomechanics, 2013.08.
7. P. Yos, M. Todo, Characterization of compressive deformation of porous HA and HA/PCL composite scaffolds for bone tissue engineering, The 7th Asian Pasific Conference on Biomechanics, 2013.08.
8. V. Vannaladsaysy, M. Todo, Tensile mechanical characteristics of core-shell hybrid structural polymer scaffold for ligament tissue engineering, The 7th Asian Pasific Conference on Biomechanics, 2013.08.
9. M. Todo, T. Arahira, In vitro bone formation by mesenchymal stem cells with 3D collagen/β-TCP composite scaffold, 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2013.07.
10. V. Vannaladsaysy, M. Todo, Development and characterization of hybrid scaffolds with core-shell structure for ligament tissue engineering, The 4th Asian Biomaterials Congress, 2013.06.
11. M. Todo, T. Arahira, Characterization of β-TCP/collagen two-phase scaffold with mesenchymal stem cells for bone tissue engineering, The 4th Asian Biomaterials Congress, 2013.06.
12. 東藤貢, モフドアヌア・モフドアフザン, 日垣秀彦, 三浦裕正, 長嶺隆二, Development of computational knee simulator for biomechanical analysis of TKA, 第44回日本人工関節学会, 2013.02.
13. 東藤 貢, Mohd Anuar Mohd Afzan, スクワット動作時のPS型人工膝関節における応力集中解析, 日本機械学会第25回計算力学講演会, 2012.10.
14. 東藤 貢, Phanny Yos, 骨組織工学用多孔質HAp/PCL複合材料の力学特性, 日本機械学会M&M2012材料力学カンファレンス, 2012.09.
15. 東藤 貢, Vilay Vannaladsaysy, 靭帯再生のためのコラーゲン/PCL複合系scaffoldの引張り変形挙動, 日本機械学会M&M2012材料力学カンファレンス, 2012.09.
16. Fracture property and fracture mechanism of HA/PLLA/PCL composite material.
17. Fracture behavior and fracture mechanism of PLLA/PCL and PLLA/PCL/PLLA-CL blends.
18. Stress analysis of artificial knee joint using dynamic finite element method.
19. 3-D contact analysis of artificial knee joint using finite element method.
20. Development and fracture property evaluation of bioabsorbable materials.
21. Effect of LTI addition on fracture behavior of PLA/PCL blend.
22. Application of computational mechanics on impact toughness evaluation of polymer blend.
23. Finite element modeling of TKA operated bone using image data.
Membership in Academic Society
  • The Japanese Society for Regenerative Medicine
  • Japanese Society of Clinical Biomechanics
  • The Japan Society of Mechanical Engineers
  • Japanese Soceity for Biomaterials
Educational
Educational Activities
I teach the corse of Fracture Sciene of Materials and Strength of ADvanced Materials at the Interdisciplinary Graduate School of Material Sciences.
These corses are especially for Master's students. I also teach the course of applied mathematics and mechanics of deformable body for foreign students in English.
I also supervise students of Masters and PhD courses to conduct their research works and write Masters and PhD thesis.
Social
Professional and Outreach Activities
1995-1999: International cooperative research project on effects of loading-rate on fracture mechanism and fracture behavior of polymer composite materials was conducted with researchers from Swiss Federal Institute of Technology and The Australian National University..