Kyushu University Academic Staff Educational and Research Activities Database
List of Presentations
Masayuki Sasaki Last modified date:2019.09.06

Professor / Graduate School of Medical Sciences, Faculty of Medicine, Department of Health Sciences, Medical Quantum Science / Department of Health Sciences / Faculty of Medical Sciences


Presentations
1. Tetsu Nakaichi, Masayuki Sasaki, The impact of respiratory motion and image noise on the accuracy and variability of PET-derived volumetric parameters., 65th Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2018.06.
2. Yuji Tsutsui, Masayuki Sasaki, The Japanese harmonization technology study for multicenter analysis of PET SUV using vendor-neutral software: J-Hart study., 65th Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2018.06.
3. Natsumi Shimokawa, Masayuki Sasaki, The effect of different regions of interest on the quantitative evaluation in amyloid PET images., 65th Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2018.06.
4. Natsumi Shimokawa, Masayuki Sasaki, A comparison and examination of visual and quantitative evaluations in amyloid positron emission tomography., 65th Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2018.06.
5. Saki Kimoto, Masayuki Sasaki, The evaluation of the spatial resolution of 11C-, 18F- and 64Cu-PET images on a clinical PET/CT scanner using Monte Carlo Simulation and phantom examination, 65th Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2018.06.
6. Saki Kimoto, Masayuki Sasaki, The influence of time of flight (TOF) information on scatter fraction and the effect of scatter correction on 18F-PET images., 65th Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2018.06.
7. Ayano Shoji, Masayuki Sasaki, A Gaussian filter influenced the evaluation of heterogeneity on PET images, 65th Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2018.06.
8. Natsumi Shimokawa, Go Akamatsu, Miyako Kadosaki, Ayano Shoji, Naoki Hashimoto, Saki Kimoto, Masayuki Sasaki, Influence of regions-of-interest template on the quantitative evaluation of amyloid PET, 第74回 日本放射線技術学会総会学術大会, 2018.04.
9. Natsumi Shimokawa, Go Akamatsu, Miyako Kadosaki, Ayano Shoji, Naoki Hashimoto, Saki Kimoto, Masayuki Sasaki, Relationship between visual judgement and quantitative values in amyloid PET, 第74回 日本放射線技術学会総会学術大会, 2018.04.
10. Saki Kimotoa, Masayuki Sasaki, The evaluation of the spatial resolution of 11C-, 18F- and 64Cu-PET images using phantom examination and simulation, 第74回 日本放射線技術学会総会学術大会, 2018.04.
11. Toshiki Takeshita, Masayuki Sasaki, Influence of respiratory motion on radiomics analyses of intratumoral heterogeneity in PET/CT imaging, 第74回 日本放射線技術学会総会学術大会, 2018.04.
12. Ayano Shoji, Masayuki Sasaki, Influence of a Gaussian filter on the evaluation of the PET heterogeneity, 第74回 日本放射線技術学会総会学術大会, 2018.04.
13. Naoki Hashimoto, Masayuki Sasaki, The effect of a smoothing filter on small lesion detectability with a clinical PET/CT , 第37回 日本核医学技術学会総会学術大会, 2017.10.
14. Saki Kimoto, Masayuki Sasaki, The evaluation of the spatial resolution of 64Cu-PET images using a clinical PET/CT scanner, 第37回 日本核医学技術学会総会学術大会, 2017.10.
15. Ayano Shoji, Masayuki Sasaki, The characteristics of parameters in texture analysis for evaluating heterogeneity, 第37回 日本核医学技術学会総会学術大会, 2017.10.
16. Kei Wagatsuma, Masayuki Sasaki, Validation study of new cross calibration method using NIST traceable 68Ge/68Ga source kit, 64th Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2017.06.
17. Yuji Tsutsui, Masayuki Sasaki, The Influence of Smoothing Filters on FDG PET Harmonization, 64th Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2017.06.
18. Ryota Oshima, Akihiko Takahashi, Masayuki Sasaki, Impact of Collimator on Ra-223 Imaging: a Monte-Carlo Study, 64th Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2017.06.
19. Saki Kimoto, Masayuki Sasaki, The relationship between positron emitting nuclides and spatial resolution using clinical PET/CT scanner, 64th Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2017.06.
20. Ayano Shoji, Masayuki Sasaki, The influence of the subset number on the quality of OSEM-reconstructed PET images, 64th Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2017.06.
21. Ayano Shoji, Masayuki Sasaki, The influence of a post filter for evaluating heterogeneity on PET images, 64th Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2017.06.
22. Naoki Hashimoto, Masayuki Sasaki, The evaluation of the heterogeneity in brain dopamine transporter SPECT imaging with an anthropomorphic striatal phantom, 64th Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2017.06.
23. Naoki Hashimoto, Masayuki Sasaki, The small lesion detectability in different target-to-background ratios of radioactivity with a clinical PET/CT scanner., 64th Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2017.06.
24. Yuji Tsutsui, Masayuki Sasaki, The Characteristics of the Smoothing Filters in FDG PET Harmonization, 第73回 日本放射線技術学会総会学術大会, 2017.04.
25. Tetsu Nakaichi, Masayuki Sasaki, Influence of Standardized Uptake Value Variation on Volumetric Parameters using Adaptive Threshold Segmentation Method, 第73回 日本放射線技術学会総会学術大会, 2017.04.
26. Shinji Amakusa, Masayuki Sasaki, Differences of Edge Artifacts on 68Ga-PET images and 18F-PET images Using PSF Correction., 第73回 日本放射線技術学会総会学術大会, 2017.04.
27. Ayano Shoji, Masayuki Sasaki, Effects of subset number in PET image reconstruction on the image quality, 第73回 日本放射線技術学会総会学術大会, 2017.04.
28. Saki Kimoto, Masayuki Sasaki, The influence of the radioisotopes on the spatial resolution of PET images, 第73回 日本放射線技術学会総会学術大会, 2017.04.
29. Naoki Hashimoto, Masayuki Sasaki, The assessment of small lesion detection in low background radioactivity with PET/CT, 第73回 日本放射線技術学会総会学術大会, 2017.04.
30. Naoki Hashimoto, Masayuki Sasaki, The evaluation of heterogeneity in brain dopamine transporter SPECT images, 第73回 日本放射線技術学会総会学術大会, 2017.04.
31. Naoki Hashimoto, Masayuki Sasaki, Point-spread-function model improved detectability of sub-centimeter hot lesions using clinical PET/CT device., International Conference on Medical Physics 2016, 2016.12.
32. Keishin Morita, Masayuki Sasaki, The impact of reconstruction algorithms on the evaluation of the heterogeneity in 18F-FDG PET., International Conference on Medical Physics 2016, 2016.12.
33. Yasuhiro Maruoka, Masayuki Sasaki, Prediction of balloon pulmonary angioplasty response for chronic thromboembolic pulmonary hypertension using frtactal analysis of 99mTc-MAA SPECT., 63rd Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2016.06.
34. Kitamura Yoshiyuki, Masayuki Sasaki, Relationship of the I-123 Metaiodobenzylguanidine (MIBG) uptake and early relapse of neuroblastoma using semi-quantitative analysis of SPECT/CT., 63rd Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2016.06.
35. Go Akamatsu, Masayuki Sasaki, Automated PET-only quantification of amyloid deposition with adaptive atlas and empirically pre-defined ROI template., 63rd Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2016.06.
36. Kei Wagatsuma, Masayuki Sasaki, Scatter limitation correction can avoid scatter correction error caused by a high radioactivity in the facemask in an oxigen-15 labeled gas-inhalation PET study, 63rd Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2016.06.
37. Hiroki Tsuru, 佐々木 雅之, Time-of-flight information improves the detectability of sub-centimeter lesions using clinical PET/CT system., 63rd Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2016.06.
38. 守田 圭伸, 佐々木 雅之, Standardization of brain dopamine transporter SPECT with a fan-beam collimator., 63rd Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2016.06.
39. 守田 圭伸, 佐々木 雅之, Different image reconstruction methods resulted in different level of heterogeneity in texture analysis of PET images. , 63rd Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2016.06.
40. Kitamura Yoshiyuki, 佐々木 雅之, Usefullness of Semi-quantitative Analysis in I-123 Metaiodobenzylguanidine Scintigraphy for Differentiation of Pheochromocytoma and Cortical Adenoma., 第75回 日本医学放射線学会総会, 2016.04.
41. Hiroki Tsuru, 佐々木 雅之, Factors that affect the liver standardized uptake value in baseline 18F-FDG PET/CT., 第72回 日本放射線技術学会総会学術大会, 2016.04.
42. Keishin Morita, 佐々木 雅之, Evaluation of texture analysis for the heterogeneous uptake on PET images., 第72回 日本放射線技術学会総会学術大会, 2016.04.
43. Keishin Morita, 佐々木 雅之, The evaluation of the reconstruction parameters of brain dopamine transporter SPECT images with a fan-beam collimator and a comparison with parallel collimators., 第72回 日本放射線技術学会総会学術大会, 2016.04.
44. 赤松 剛, 佐々木 雅之, 千田 道雄, Automated PET-only quantification of amyloid deposition with adaptive template and amyloid-specific region-of-interest., EANM2015, 28th Annual Congress of European Association of Nuclear Medicine, 2015.10.
45. Shingo Baba, 磯田 卓郎, 佐々木 雅之, Hiroshi Honda, Usefulness of FDG-PET/CT in the diagnosis of acute transformation of Adult T-cell Lymphoma. , 62nd Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2015.06.
46. 磯田 卓郎, Shingo Baba, 佐々木 雅之, Hiroshi Honda, Use of recombinant human thyroid-stimulating hormone (rhTSH) reduces the damage to salivary glands after radioiodine therapy for thyroid cancer. , 62nd Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2015.06.
47. 筒井 悠治, 氷室 和彦, 赤松 剛, 佐々木 雅之, Edge artifacts in PSF based PET reconstruction in relation to the reconstruction parameters, 62nd Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2015.06.
48. Miwa Kenta, 佐々木 雅之, Impact of scatter limitation correction on photopenic artifacts caused by patient motion during whole-body PET/CT. , 62nd Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2015.06.
49. Miwa Kenta, 佐々木 雅之, Performance characteristics of a novel clustered multi-pinhole technology for simultaneous high-resolution SPECT/PET., 62nd Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2015.06.
50. 芝 弘晃, A.Takahashi, 氷室 和彦, Shingo Baba, 佐々木 雅之, Comparison images between PET and SPECT using 90Y : A Monte-Carlo simulation study, 62nd Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2015.06.
51. 守田 圭伸, 筒井 悠治, 氷室 和彦, Shingo Baba, 佐々木 雅之, The effects of reconstruction parameters on the evaluation of heterogeneity of the F-18 distribution using three analytic methods , 62nd Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2015.06.
52. 前畠 彬, 筒井 悠治, 氷室 和彦, Shingo Baba, 佐々木 雅之, The relationship between the variance of the measured count and the alignment of the point source on PET images., 62nd Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2015.06.
53. 前畠 彬, 今村 綾花, 国府寺 由依, 山下 泰生, 小宮 勲, 佐々木 雅之, Shingo Baba, Evaluation of brain dopamine transporter SPECT images using iterative reconstruction and attenuation correction, 62nd Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2015.06.
54. Akira Maebatake, Yuji Tsutsui, 三輪 建太, Kazuhiko Himuro, Shingo Baba, Masayuki Sasaki, The relationship between the variance of the measured count and the alignment of the point source on PET images., 第71回 日本放射線技術学会総会学術大会, 2015.04.
55. Hiroaki Shiba, Hidetoshi Eto, Kosuke Yamada, Akihiko Takahashi, 佐々木 雅之, Kazuhiko Himuro, Yasuo Yamashita, Shingo Baba, Isao Komiya, Monte Carlo simulation of PET and SPECT of 90Y, 第71回 日本放射線技術学会総会学術大会, 2015.04.
56. Keishin Morita, Toshiki Takeshita, 三輪 建太, Akira Maebatake, Yuji Tsutsui, Shingo Baba, Masayuki Sasaki, Influence of reconstruction parameters on evaluation of the heterogeneity of [18F]-fluorodeoxyglucose uptake in positron emission tomography, 第71回 日本放射線技術学会総会学術大会, 2015.04.
57. Go Akamatsu, Yasuhiko Ikari, Akihito Ohnishi, Tomoyuki Nishio, Hiroyuki Nishida, Masayuki Sasaki, Michio Senda, A new method to calculate standardized uptake value ratio using CT images for amyloid PET/CT images., 第71回 日本放射線技術学会総会学術大会, 2015.04.
58. Go Akamatsu, Yasuhiko Ikari, Hiroyuki Nishida, Tomoyuki Nishio, Akihito Ohnishi, Michio Senda, 佐々木 雅之, Effect of statistical noise on reproducibility and accuracy of maximum and peak SUV: a phantom study. , The 4th Annual International Asian Society of Nuclear Medicine Technology Conference, 2014.11.
59. Shingo Baba, TAKURO ISODA, Yasuhiro Maruoka, Yoshiyuki Kitamura, 長尾 充展, 佐々木 雅之, Hiroshi Honda, Usefulness of myocardial 123I-MIBG-SPECT for the differential diagnosis of Parkinson's syndrome, 61st Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2014.06.
60. Yasuhiro Maruoka, Shingo Baba, TAKURO ISODA, Yoshiyuki Kitamura, 佐々木 雅之, Hiroshi Honda, Relationship between Effectiveness of I-131 Therapy and 18F-FDG accumulation in Differentiated Thyroid Carcinoma patients with lung metastasis , 61st Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2014.06.
61. Yoshiyuki Kitamura, Shingo Baba, TAKURO ISODA, Yasuhiro Maruoka, Yoshio Matsuo, 佐々木 雅之, Hiroshi Honda, Comparison between lacrimal gland tumors of IgG4-related disease and MALT lymphoma at FDG PET/CT, 61st Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2014.06.
62. Yoshiyuki Kitamura, Shingo Baba, TAKURO ISODA, Yasuhiro Maruoka, 佐々木 雅之, Hiroshi Honda, Efficiency of the respiratory gating 18F-FDG PET/CT at lung adenocarcinoma: comparison between the amplitude gating method and the phase gating method , 61st Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2014.06.
63. TAKURO ISODA, Yoshiyuki Kitamura, Yasuhiro Maruoka, Shingo Baba, 佐々木 雅之, Hiroshi Honda, Evaluation of Diagnostic Performance of a Computer-Aided Diagnostic System, BONENAVI, on Bone Scintigraphy Images , 61st Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2014.06.
64. 赤松 剛, Hiroyuki Nishida, Yasuhiko Ikari, Tomoyuki Nishio, Akihito Ohnishi, Michio Senda, 佐々木 雅之, Effect of image noise in reproducibility and accuracy of standardized uptake values: a phantom study., 61st Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2014.06.
65. 赤松 剛, Yasuhiko Ikari, Tomoyuki Nishio, Hiroyuki Nishida, Akihito Ohnishi, Michio Senda, 佐々木 雅之, Optimization of reconstruction parameters for FDG and amyloid brain PET imaging. , 61st Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2014.06.
66. 前畠 彬, 佐藤 真帆, 加々美 るり子, 谷口 隆文, 木寺 大輔, 三笠 翔平, 山下 泰生, 小宮 勲, 佐々木 雅之, Evaluation of the quantitative analysis of brain dopamine transporter SPECT images between different SPECT/CT devices. , 61st Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2014.06.
67. 前畠 彬, 谷口 隆文, 木寺 大輔, 三笠 翔平, 加々美 るり子, 佐藤 真帆, 筒井 悠治, 小宮 勲, 佐々木 雅之, Variation in image quality with respect to difference in the frame number and acquisition time on PET/CT, 61st Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2014.06.
68. 木寺 大輔, 赤松 剛, 谷口 隆文, 三笠 翔平, 小宮 勲, 筒井 悠治, 佐々木 雅之, Quantitative evaluation of edge artifacts on PET images of PSF-based reconstruction at different radioactivity concentrations., 61st Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2014.06.
69. 三笠 翔平, 赤松 剛, 谷口 隆文, 木寺 大輔, 木原 謙, 松岡 光貴, 甘艸 慎史, 吉田 毅, 佐々木 雅之, Shingo Baba, 筒井悠治, A study of the influence of partial volume correction on the heterogeneous FDG uptake of multiple metastases in patients with breast cancer., 61st Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2014.06.
70. Yasuhiro Maruoka, Masayuki Sasaki, Association between response to I-131 therapy and 18F-FDG accumulation for differentiated thyroid carcinoma patients with lung metastasis, 第73回 日本医学放射線学会総会, 2014.04.
71. Kenta Miwa, Masayuki Sasaki, Performance characteristics of clustered multi-pinhole technology for simultaneous high-resolution SPECT/PET, 第70回 日本放射線技術学会総会学術大会, 2014.04.
72. Norikazu MATSUTOMO, Masayuki Sasaki, Impact of PSF and TOF correction for myocardial FDG PET imaging: Quantitative analysis of phantom and clinical studies, 第70回 日本放射線技術学会総会学術大会, 2014.04.
73. Go Akamatsu, Masayuki Sasaki, Optimization of image reconstruction parameters for FDG and amyloid brain PET imaging, 第70回 日本放射線技術学会総会学術大会, 2014.04.
74. Shohei Mikasa, Masayuki Sasaki, Influence of partial volume correction on heterogeneous fluorodeoxyglucose uptake by multiple metastatic lesions in patients with breast cancer, 第70回 日本放射線技術学会総会学術大会, 2014.04, Purpose: Heterogeneous fluorodeoxyglucose (FDG) uptake is frequently observed in FDG-PET studies of patients with multiple metastatic lesions. In this study, we examined the influence of partial volume correction (PVC) on heterogeneous FDG uptake by multiple metastatic lesions in patients with breast cancer.
Methods: One hundred thirty-three lesions were examined from 22 breast cancer patients with multiple metastatic lesions. The lesions consisted of 13 primary tumors, 78 metastatic lymph nodes, and 42 distant metastases. Sixty minutes after FDG administration, PET/CT scans were performed with the Bigraph mCT scanner or the Discovery STE scanner. We measured the maximum standardized uptake values (SUVmax) and backgrounds of these lesions on PET images and the short-axis diameter on CT images. PVC was performed by using the correction table for each PET scanner generated from the measured recovery coefficient (RC) curve and the approximated point spread function. We obtained corrected SUVmax (cSUVmax) by using PVC.
Results: For all lesions, the mean, the standard deviation (SD), and the coefficient of variance (CV) of the SUVmax were 7.66, 4.91, and 64.1%, respectively. After PVC, the mean, the SD, and the CV of cSUVmax were 11.00, 4.83, and 43.7 %, respectively. For each patient, the CV ranged from 14.3% to 92.0% with a mean of 51.3%. After PVC, the CV of the cSUVmax ranged from 7.0% to 57.0% with a mean of 27.8%. In 21 of 22 patients, the CV reduced after PVC.
Conclusion: The heterogeneity of FDG uptake on multiple metastatic lesions in patients with breast cancer reduced after PVC. Therefore, the performance of PET/CT scanner may contribute to the heterogeneity of tumor FDG uptake..
75. Kenta Miwa, Masayuki Sasaki, FDG uptake heterogeneity evaluated by fractal analysis improves the differential diagnosis of pulmonary nodules., RSNA2013, 99th Scientific Assembly and Annual Meeting, Radiological Society of North America, 2013.12.
76. Kenta Miwa, Masayuki Sasaki, Comparison of intratumoral 18FDG and 18FAZA distribution in non-small cell lung cancer using deformable image registration., RSNA2013, 99th Scientific Assembly and Annual Meeting, Radiological Society of North America, 2013.12.
77. Hidetaka Arimura, Masayuki Sasaki, Automated Method for Extraction of Lung Tumors Using a Machine Learning Classifier with Knowledge from Radiation Oncologists on Data Sets of Planning CT and FDG-PET/CT Images, 35th Annual International IEEE EMBS, 2013.07.
78. 松友 紀和, Hideo Onishi, Akio Nagaki, Keiichi Matsumoto, 佐々木 雅之, Usefulness of CT iterative reconstruction method for low-dose CT attenuation correction on the accuracy of PET image in obesity phantom study., 60th Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2013.06.
79. 田仲 由香, 近藤 晃, 佐々木 克己, 赤松 剛, 谷口 隆文, 佐々木 雅之, A study of the calculation methods used to eliminate the body weight dependency of SUV., 60th Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2013.06.
80. 赤松 剛, 谷口 隆文, 木原 謙, 木寺 大輔, 三笠 翔平, 小宮 勲, 佐々木 雅之, A new method to evaluate the PET image quality based on the image noise and reproducibility of recovery coefficients. , 60th Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2013.06.
81. 赤松 剛, 姥 浩二, 谷口 隆文, 光元 勝彦, 成末 彰博, 筒井 悠治, 佐々木 雅之, A comparison of the imaging performance of 39- and 52-ring time-of-flight PET/CT scanners using a NEMA body phantom., 60th Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2013.06, Purpose: We evaluated the imaging performance of 39- and 52-ring time-of-flight (TOF) PET/CT scanners. We then assessed the potential of reducing the scan time using a 52-ring PET/CT scanner.
Materials and Methods: The Biograph mCT scanners with 39- and 52-ring LSO detectors with TOF correction were evaluated. The axial field-of-view was 16.2 and 21.6 cm, respectively. We used a NEMA IEC body phantom filled with an 18F solution containing a background activity of 5.31 and 2.65 kBq/ml for the studies. The sphere-to-background ratio was 4:1. The PET data were acquired for 10 minutes in 3-dimensional list-mode, and then reconstructed with an OSEM+PSF+TOF algorithm. PET images with different acquisition times were reconstructed (from 1 to 10 minutes). The image quality was physically assessed using the noise-equivalent count rate (NECR), contrast of hot spheres (CONT) and coefficient of variation of background activity (CV).
Results: The number of bed positions of the 52-ring system was 25% lower than that of the 39-ring system. Compared to the 39-ring system, the NECR of the 52-ring system was 60% higher for both the high and low activity models. The CONT was consistent, irrespective of the number of detector rings and the activity levels. The CV of the 52-ring system for 3 minutes acquisition was equivalent to that of the 39-ring system for 4 minutes acquisition.
Conclusions: Based on these results, the acquisition time of the 52-ring system can be reduced by about 25%. In addition, the number of bed positions required is 25% lower for the 52-ring system. Finally, the examination time required for a whole-body PET scan is considered to be reduced by about 40% if the 52-ring system is used..
82. 谷口 隆文, 赤松 剛, 木原 謙, 木寺 大輔, 三笠 翔平, 筒井 悠治, 小宮 勲, 佐々木 雅之, Does the different radioactivity influence the effect of PSF and TOF correction on PET/CT image quality? , 60th Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2013.06, 【Objective】The aim of this study was to investigate the effect of PSF correction and TOF correction on different radioactivity concentrations in relation to the number of iterations and acquisition times.
【Methods】This study used a Biograph mCT (Siemens Healthcare) and a NEMA IEC body phantom. The background was filled with 18F-FDG of four different radioactivity concentrations (7.95, 5.31, 2.65 and 1.325 kBq/mL), and the sphere to background ratio was 4:1. The data were acquired for 30 minutes in list mode. The reconstruction methods were OSEM, OSEM+PSF, OSEM+TOF and OSEM+PSF+TOF (iteration: 2, subset: 24 (21 in TOF), Gaussian filter: 4 mm FWHM). The image quality was evaluated using CV, CONT (contrast) and SNR in relation to the iteration numbers (1 to 10).
【Results】The CV was improved 30% by PSF correction on all background concentrations. The CONT was improved by PSF+TOF corrections. The degree of improvement was 27% for BG1.325. The SNR was improved by PSF+TOF correction. The degree of improvement was 114% for BG1.325. The SNR was highest at 2 iterations with OSEM+PSF+TOF, and at 3 iterations with OSEM+PSF.
【Conclusions】The CV was improved by PSF correction and the CONT was improved by TOF correction. The degrees of improvement of CV, CONT and SNR were the highest at BG1.325..
83. 三笠 翔平, 赤松 剛, 谷口 隆文, 木寺 大輔, 木原 謙, 松岡 光貴, 甘艸 慎史, 吉田 毅, 佐々木 雅之, Standardization of dual point FDG-PET with different PET scanners by partial volume correction., 60th Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2013.06, Purpose: Dual point FDG-PET is reported to be useful for diagnosing breast cancer. However, the standardized uptake value (SUV) varies between studies performed using different PET scanners. In this study, we examined the possibility of using the partial volume correction (PVC) to standardize FDG-PET studies with two PET scanners.
Methods: One hundred fifteen lesions from ninety-nine breast cancer patients were examined. The short-axis diameter of these lesions was 14.4 ± 8.7 mm (range: 4 to 57 mm). The first scans were performed with Advance NXi at 60 min and the second scans were performed with TruePoint Biograph 40 at 120 min after FDG injection. The maximum SUVs (SUVmax) were measured from both time points (SUVmax1 and SUVmax2). The percent change in the SUVmax (Δ%SUVmax) between the two time points was calculated. Seven spheres and the background in the NEMA IEC body phantom were filled with 18F solution with different sphere to background (SB) ratios of 8:1, 4:1, 2:1 and 1.25:1. The recovery coefficient (RC) curves were generated and were approximated with PSF. Then, we made lookup tables for the PVC of each device from the RC curves.
Results: The mean ± SD of the SUVmax1, the SUVmax2 and the Δ%SUVmax were 5.69 ± 4.45, 5.16 ± 4.27 and -9.29% ± 1.90%, respectively. After PVC, all of them significantly increased and were 11.77 ± 6.74, 11.51 ± 6.63 and -1.14% ± 2.01%, respectively. In addition, the lesions with a positive Δ%SUVmax increased after PVC, from 26.7% to 41.7%.
Conclusion: The PVC for the SUVmax is considered to be useful for standardizing dual point FDG-PET studies in patients with breast cancer performed by different PET scanners. This method is also expected to be useful for the standardization of multicenter PET studies..
84. 筒井 悠治, 木寺 大輔, 谷口 隆文, 赤松 剛, 小宮 勲, 梅津 芳幸, 佐々木 雅之, Usefulness of amplitude-based respiratory gating for PET/CT., 60th Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2013.06.
85. 木寺 大輔, 木原 謙, 赤松 剛, 谷口 隆文, 三笠 翔平, 田仲 由香, 小宮 勲, 筒井 悠治, 中村 泰彦, 佐々木 雅之, Evaluation of the edge artifact in PET images reconstructed with a PSF model., 60th Annual Meeting, Society of Nuclear Medicine and Molecular Imaging, 2013.06, Purpose: We evaluated the quantitative effect of the edge artifact on PET images reconstructed with the point-spread function (PSF) model using a NEMA body phantom.
Materials and Methods: A NEMA body phantom with 10-37 mm diameter spheres was filled with an 18F-FDG solution of a 4:1 sphere-to-background radioactivity ratio. The PET data were acquired in three-dimensional list mode for 20 min using a Biograph mCT scanner. The PET data were reconstructed with the baseline ordered-subsets expectation maximization (OSEM) and with the OSEM+PSF model (PSF). We varied the number of iterations and the image matrix in all reconstruction models. The phantom PET image analyses were performed by visual assessment of a profile and a calculation of the ratio of the maximum counts in the hot sphere to the background.
Results: In large spheres (37, 28 and 22 mm in diameter), an edge artifact was observed as an overshoot along the edge of spheres in the PSF images at an iteration number of two or higher. The artifact became prominent with the increase in the number of iterations. In small spheres (17, 13 and 10 mm in diameter), the artifact appeared as an overshoot in the center of spheres. The peak value in the 13 mm sphere was about 60% higher than the actual radioactivity. The artifact was prominent at high pixel numbers (256×256 and 512×512).
Conclusion: The edge artifact in PET images reconstructed using the PSF appeared clearly with increasing the iteration number, and was seen at both 256×256 and 512×512. Appropriate reconstruction parameters should be determined, because the edge artifact is considered to result in an overestimation of hot lesions. .
86. 三輪 建太, Hidenobu Tachibana, Masayuki Inubushi, Kei Wagatsuma, Taisuke Murata, Tomoyuki Takiguchi, Mitsuru Koizumi, Tsuneo Saga, 佐々木 雅之, Comparison of intratumoral distribution of 18FDG and 18FAZA using deformable image registration procedure in non-small cell lung cancer patients, 第69回 日本放射線技術学会総会学術大会, 2013.04.
87. 三笠 翔平, 赤松 剛, 谷口 隆文, 木寺 大輔, 木原 謙, 松岡 光貴, 甘艸 慎史, 吉田 毅, 佐々木 雅之, Standardization of dual point FDG-PET with different PET scanners by partial volume correction, 第69回 日本放射線技術学会総会学術大会, 2013.04.
88. 木寺 大輔, 木原 謙, 赤松 剛, 谷口 隆文, 三笠 翔平, 田仲 由香, 小宮 勲, 筒井 悠治, 中村 泰彦, 佐々木 雅之, Evaluation of the edge artifact in PET images reconstructed with a PSF model, 第69回 日本放射線技術学会総会学術大会, 2013.04.
89. 赤松 剛, 谷口 隆文, 木原 謙, 木寺 大輔, 三笠 翔平, 筒井 悠治, 佐々木 雅之, A new method to evaluate the PET image quality based on the image noise and reproducibility of recovery coefficients, 第69回 日本放射線技術学会総会学術大会, 2013.04.
90. 谷口 隆文, 赤松 剛, 木原 謙, 木寺 大輔, 三笠 翔平, 小宮 勲, 筒井 悠治, 佐々木 雅之, Effect of point-spread-function and time-of-flight for PET/CT image quality in relation to radioactivity levels, 第69回 日本放射線技術学会総会学術大会, 2013.04, 【Objective】The aim of this study was to investigate the effect of PSF correction and TOF correction on PET/CT image quality at different radioactivity concentrations, in relation to the number of iterations and the acquisition times.
【Materials and Methods】This study used a Biograph mCT (Siemens Healthcare) and a NEMA IEC body phantom. The background was filled with 18F-FDG of four different radioactivity concentrations: 7.95, 5.31, 2.65 and 1.325 kBq/mL, and the sphere-to-background ratio was 4:1. The data were acquired for 30 minutes in list mode. The reconstruction methods were OSEM, OSEM+PSF, OSEM+TOF and OSEM+PSF+TOF. The experimental setting for the number of iterations, subset and Gaussian filter were 2, 24 (21 for TOF) and 4 mm (FWHM). The image quality was evaluated by the CV, CONT (contrast) and SNR, in relation to the iteration numbers (1 to 10).
【Results】With the PSF correction, the CV was improved by 30% for all background concentrations. The CONT was improved by 26% with both the TOF and PSF+TOF corrections for BG2.65. The SNR was improved using PSF+TOF correction. The degree of improvement was more than 90% for BG2.65 and BG7.95. Further, the SNR increased with higher radioactivity, and it was highest at 2 iterations with OSEM+PSF+TOF, and at 3 iterations with OSEM+PSF.
【Conclusions】Both CV and Contrast were improved using the PSF correction and TOF correction. The improvement of the CV was independent of the radioactivity, whereas that of the CONT varied based on the radioactivity..