| Kazuhiko Nakamura | Last modified date：2012.5.29 |
Assistant Professor /
Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University
Department of Hepatology and Pancreatology
Kyushu University Hospital
Department of Hepatology and Pancreatology
Kyushu University Hospital
Graduate School
Undergraduate School
Administration Post
Other
Other
Other
E-Mail
Homepage
http://www.med.kyushu-u.ac.jp/intmed3/
HP of the Department of Medicine and Bioregulatory Sciences, Kyushu University.
Phone
092-642-5286
Fax
092-642-5287
Academic Degree
M. D., Ph. D.
Field of Specialization
Gastroenterology
Outline Activities
Research: I am studying mechanisms of inflammatory bowel diseases, such as ulcerative colitis and Crohns disease, from mucosal immunological stand point, and trying to utilize such outcome to establish new therapies for those diseases.
Education: I give lectures on gastroenterology to medical students and instruct madical students in clinical training. I teach gastroenterological endoscopy and radiology to young doctors.
Social activity: I give seminars on diagnosis and treatment of inflammatory bowel disease to citizens.
Education: I give lectures on gastroenterology to medical students and instruct madical students in clinical training. I teach gastroenterological endoscopy and radiology to young doctors.
Social activity: I give seminars on diagnosis and treatment of inflammatory bowel disease to citizens.
Research
Research Interests
- Study for the dysregulation of immunity in the gut of inflammatory bowel diseases
keyword : inflammatory bowel disease, mucosal immunity, cytokine
2002.04. - Study for the mechanism of post-inflammatory irritable bowel syndrome and the development of the new therapy.
keyword : irritable bowel syndrome, immunity, colitis
2004.05～2012.05. - Study for the diagnosis for gastrointestinal, pancreatic and biliary disorders using endoscopic ultrasonography.
keyword : endoscopic ultrasonography, gastrointestinal disease, pancreatic disease, biliary disease
2004.05～2012.05.
- We conduct studies for the development of new tharapies for inflammatory bowel disease
- We conduct studies for generation of new therapies for inflammatory bowel disease.
Papers
| 1. | Iwasa,T.,Ogino,H.,Nakamura,K.,Ihara,E.,Akiho,H.,Takayanagi,R,Feeding Administration of Daikenchuto Suppresses Colitis Induced by Naive CD4⁺TCell Transfer into SCID Mice,Digestive Diseases and Sciences,2012 May 19 Epub ahead of print,2012.05. |
| 2. | Somada S, Muta H, Nakamura K, Sun X, Honda K, Ihara E, Akiho H, Takayanagi R, Yoshikai Y, Podack ER, Tani K,CD30 Ligand/CD30 Interaction is Involved in Pathogenesis of Inflammatory Bowel Disease,Digestive Diseases and Sciences,2012 Mar 27 Epub ahead of print,2012.03. |
| 3. | Ogino H, Nakamura K, Iwasa T, Ihara E, Akiho H, Motomura Y, Akahoshi K, Igarashi H, Kato M, Kotoh K, Ito T, Takayanagi R,Regulatory T Cells expanded by rapamycin in vitro suppress colitis in an experimental mouse model,J Gastroenterol,Vol.47,No.4,pp.366-376,2011 Dec 22. Epub ahead of print,2011.12. |
| 4. | Kanayama K, Nakamura K, Ogino H, Sumida Y, Ihara E, Akiho H, Takayanagi R,Th1 Responses Are More Susceptible to Infliximab-mediated Immunosuppression than Th17 Responses.,Digestive Diseases and Sciences,Vol.56,pp.3525-3533,2011.12. |
| 5. | Ogino H, Nakamura K, Ihara E, Akiho H, Takayanagi R,CD4+CD25+ Regulatory T Cells Suppress Th17-Responses in the Experimental Colitis Model ,Digestive Diseases and Sciences,Vol.56,No.2,pp.376-386,2011.02. |
| 6. | Mizutani T, Akiho H, Khan WI, Murao H, Ogino H, Kanayama K, Nakamura K, Takayanagi R,Persistent gut motor dysfunction in a murine model of T-cell-induced enteropathy. ,Neurogastroenterol Motil,Vol.22,No.2,pp.196-203,2010.02. |
| 7. | Kubo H, Nakamura K, Itaba S, Yoshinaga S, Kinukawa N, Sadamoto Y, Ito T, Yonemasu H, Takayanagi R,Differential diagnosis of cystic tumors of the pancreas by endoscopic ultrasonography. ,Endoscopy ,41: 684-689, 2009.,2009.08. |
| 8. | Sumida Y, Nakamura K, Kanayama K, Akiho H, Teshima T, Ryoichi T,Preparation of functionally preserved CD4+CD25high regulatory T cells from leukapheresis products from ulcerative colitis patients, applicable to regulatory T-cell-transfer therapy.,Cytotherapy,10巻、7号、698－710頁,2008.12. |
| 9. | Nakamura K, Kitani A, Fuss I, Pedersen A, Harada N, Nawata H, Strober W.,TGF-b1 plays an important role in the mechanism of CD4+CD25+ regulatory T cell acitivity in both humans and mice.,Journal of Immunology,Vol.172,pp.834-42,172巻、834-842頁,2004.01. |
| 10. | Kitani A, Fuss IJ, Nakamura K, Kumaki F, Usui T, Strober W,TGF-b1 producing regulatory T cells induce Smad-mediated IL-10 secretion that facilitates coordinated immunoregulatory activitiy and amelioration of TGF-b1 mediated fibrosis.,Journal of Experimental Medicine,Volume 198, Number 8, Pages 1179-1188,2003.10. |
| 11. | Nakamura K, Kitani A, Strober W,Cell contact-dependent immunosuppression by CD4+CD25+ regulatory T cell is mediated by cell surface-bound transforming growth factor b.,Journal of Experimental Medicine,Vol.194,No.5,pp.629-44,Volume 194, Number 5, Pages 629-644.,2001.09. |
Educational
Educational Activities
I give lectures on "esophageal diseases" and "gastroduodenal tumors" to medical students in the third year. I give a lecture on "methods of physical examination of abdomen and extremities" to medical students in the fourth year. I am an examiner of tests for physical examination of abdomen for medical students in the fourth year. I instruct medical students in the fourth and fifth years in the clinical training.
Social
The fact that no permission it reprints contents of this data base is prohibitted.