| 1. |
Yoshida S, Ohno Y, Nagafuji K, Yoshimoto G, Sugio T, Kamimura T, Ohta T, Takase K, Henzan H, Muta T, Iwasaki H, Ogawa R, Eto T, Akashi K, Miyamoto T.
, Comparison of calcineurin inhibitors in combination with conventional methotrexate, reduced methotrexate, or mycophenolate mofetil for prophylaxis of graft-versus-host disease after umbilical cord blood transplantation.
, Ann Hematol. , 98, 11, 2579-2591, 2019.11. |
| 2. |
Takaki-Kuwahara A, Arinobu Y, Miyawaki K, Yamada H, Tsuzuki H, Irino K, Ayano M, Kimoto Y, Mitoma H, Akahoshi M, Tsukamoto H, Horiuchi T, Niiro H, Akashi K.
, CCR6+ group 3 innate lymphoid cells accumulate in inflamed joints in rheumatoid arthritis and produce Th17 cytokines., Arthritis Res Ther., 21, 1, 198-198, 2019.08. |
| 3. |
Kodama T, Kochi Y, Nakai W, Mizuno H, Baba T, Habu K, Sawada N, Tsunoda H, Shima T, Miyawaki K, Kikushige Y, Mori Y, Miyamoto T, Maeda T, Akashi K.
, Anti-GPRC5D/CD3 Bispecific T-Cell-Redirecting Antibody for the Treatment of Multiple Myeloma.
, Mol Cancer Ther., 18, 9, 1555-1564, 2019.09. |
| 4. |
Nagafuji K, Miyamoto T, Eto T, Ogawa R, Okumura H, Takase K, Kawano N, Miyazaki Y, Fujisaki T, Wake A, Ohno Y, Kurokawa T, Kamimura T, Takamatsu Y, Yokota S, Akashi K.
, Prospective evaluation of minimal residual disease monitoring to predict prognosis of adult patients with Ph-negative acute lymphoblastic leukemia.
, Eur J Haematol. 2, 103, 3, 164-171, 2019.09. |
| 5. |
Matsuoka S, Hashimoto D, Kadowaki M, Ohigashi H, Hayase E, Yokoyama E, Hasegawa Y, Tateno T, Chen X, Aoyama K, Oka H, Onozawa M, Takeda K, A
, Myeloid differentiation factor 88 signaling in donor T cells accelerates graft-versus-host disease.
, Haematologica., 105, 1, 226-234, 2020.01. |
| 6. |
Aoki T, Kamimura T, Yoshida S, Mori Y, Kadowaki M, Kohno K, Ishihara D, Urata S, Sugio T, Kamezaki K, Kato K, Ito Y, Eto T, Akashi K, Miyamoto T.
, Safety and Seropositivity after Live Attenuated Vaccine in Adult Patients Receiving Hematopoietic Stem Cell Transplantation., Biol Blood Marrow Transplant., 24, 8, 1576-1585, 2019.08. |
| 7. |
Shimono J, Miyoshi H, Arakawa F, Yamada K, Sugio T, Miyawaki K, Eto T, Miyagishima T, Kato K, Nagafuji K, Akashi K, Teshima T, Ohshima K.
, Clinicopathological features of HCV-positive splenic diffuse large B cell lymphoma.
, Ann Hematol., 98, 5, 1197-1207, 2019.05. |
| 8. |
Yamauchi T, Miyawaki K, Semba Y, Takahashi M, Izumi Y, Nogami J, Nakao F, Sugio T, Sasaki K, Pinello L, Bauer DE, Bamba T, Akashi K, Maeda T.
, Targeting leukemia-specific dependence on the de novo purine synthesis pathway., Leukemia., 36, 2, 383-393, 2022.02. |
| 9. |
Jinnouchi F, Mori Y, Yoshimoto G, Yamauchi T, Nunomura T, Yurino A, Hayashi M, Yuda J, Shima T, Odawara J, Takashima S, Kamezaki K, Kato K, Miyamoto T, Akashi K, Takenaka K.
, Incidence of refractory cytomegalovirus infection after allogeneic hematopoietic stem cell transplantation., Int J Hematol., 115, 1, 96-106, 2022.01. |
| 10. |
Harada T, Iwasaki H, Muta T, Urata S, Sakamoto A, Kohno K, Takase K, Miyamura T, Sawabe T, Asaoku H, Oryoji K, Fujisaki T, Mori Y, Yoshimoto G, Ayano M, Mitoma H, Miyamoto T, Niiro H, Yamamoto H, Oshiro Y, Miyoshi H, Ohshima K, Takeshita M, Akashi K, Kato K.
, Outcomes of methotrexate-associated lymphoproliferative disorders in rheumatoid arthritis patients treated with disease-modifying anti-rheumatic drugs., Br J Haematol. , 62, 12, 2939-2948, 2021.12. |
| 11. |
Miyawaki K, Kato K, Sugio T, Sasaki K, Miyoshi H, Semba Y, Kikushige Y, Mori Y, Kunisaki Y, Iwasaki H, Miyamoto T, Kuo FC, Aster JC, Ohshima K, Maeda T, Akashi K.
, A Germinal Center-Associated Microenvironmental Signature Reflects Malignant Phenotype and Outcome of DLBCL
., Blood Adv. , 6, 7, 2388-2402, 2021.10. |
| 12. |
Henzan T, Yamauchi T, Yamanaka I, Sakoda T, Semba Y, Hayashi M, Kikushige Y, Mishima H, Ishimura M, Koga Y, Miyamoto T, Ohga S, Akashi K, Maeda T, Kunisaki Y.
, Granulocyte collection by polymorphonuclear cell-targeting apheresis with medium-molecular-weight hydroxyethyl starch., Int J Hematol., 114, 6, 691-700, 2021.12. |
| 13. |
Yamanaka I, Yamauchi T, Henzan T, Sakoda T, Miyamoto K, Mishima H, Ono H, Koga Y, Nakashima Y, Kato K, Miyamoto T, Mizuno S, Ogawa Y, Ohga S, Akashi K, Maeda T, Kunisaki Y.
, Optimization of lymphapheresis for manufacturing autologous CAR-T cells., Int J Hematol., 114, 4, 449-458, 2021.10. |
| 14. |
Chong Y, Ikematsu H, Tani N, Arimizu Y, Watanabe H, Fukamachi Y, Yonekawa A, Iwasaka S, Nishida R, Eriguchi Y, Miyake N, Shimoda S, Nagasaki Y, Shimono N, Akashi K.
, Clinical significance of SARS-CoV-2-specific IgG detection with a rapid antibody kit for COVID-19 patients., Influenza Other Respir Viruses. , 15, 1, 13-18, 2021.01. |
| 15. |
Mori Y, Jinnouchi F, Takenaka K, Aoki T, Kuriyama T, Kadowaki M, Odawara J, Ueno T, Kohno K, Harada T, Yoshimoto G, Takase K, Henzan H, Kato K, Ito Y, Kamimura T, Ohno Y, Ogawa R, Eto T, Nagafuji K, Akashi K, Miyamoto T.
, Efficacy of prophylactic letermovir for cytomegalovirus reactivation in hematopoietic cell transplantation: a multicenter real-world data
., Bone Marrow Transplant. , 56, 4, 853-862, 2021.04. |
| 16. |
Mori Y, Sasaki K, Ito Y, Kuriyama T, Ueno T, Kadowaki M, Aoki T, Sugio T, Yoshimoto G, Kato K, Maeda T, Nagafuji K, Akashi K, Miyamoto T; Fukuoka Blood and Marrow Transplantation Group.
, Outcome predictors after retransplantation in relapsed acute lymphoblastic leukemia: a multicenter, retrospective study., Ann Hematol., 100, 1, 197-208, 2022.11. |
| 17. |
Torisu T, Kawano S, Miyawaki K, Yamamoto H, Ihara Y, Matsuno Y, Torisu K, Sugio T, Sasaki K, Shimakawa T, Kato K, Akashi K, Nakamura S, Kitazono T.
, B cell receptor signaling related to resistance to Helicobacter pylori eradication therapy in gastric diffuse large B cell lymphoma
, Hematol Oncol., 39, 1, 145-147, 2021.02. |
| 18. |
Henzan H, Takase K, Kamimura T, Mori Y, Yoshimoto G, Iwasaki H, Nagafuji K, Ogawa R, Eto T, Uchida N, Fujisaki T, Kato K, Minami M, Kikushige Y, Akashi K, Miyamoto T; Fukuoka Blood & Marrow Transplantation Group (FBMTG).
, Correction to: Measurable residual disease after the first consolidation predicts the outcomes of patients with acute promyelocytic leukemia treated with all-trans retinoic acid and chemotherapy., Int J Hematol. , 112, 3, 431-432, 2020.09. |
| 19. |
Henzan H, Takase K, Kamimura T, Mori Y, Yoshimoto G, Iwasaki H, Nagafuji K, Ogawa R, Eto T, Uchida N, Fujisaki T, Kato K, Minami M, Kikushige Y, Akashi K, Miyamoto T; Fukuoka Blood & Marrow Transplantation Group (FBMTG).
, Measurable residual disease after the first consolidation predicts the outcomes of patients with acute promyelocytic leukemia treated with all-trans retinoic acid and chemotherapy., Int J Hematol. , 112, 3, 349-360, 2020.09. |
| 20. |
Uchida N, Matsumoto K, Sakura T, Hidaka M, Miyamoto T, Eto T, Maeda Y, Murayama T, Fujishima N, Yoshimoto G, Morita K, Kishimoto J, Teshima T, Taniguchi S, Yamashita T, Mori SI, Akashi K, Harada
, Myeloablative intravenous busulfan-containing regimens for allo-HSCT in AML or MDS patients over 54 years old: combined results of three phase II studies., Int J Hematol., 112, 4, 510-523, 2020.10. |
| 21. |
Arita T, Maruyama T, Yokoyama T, Hieda M, Fukata M, Fujino T, Mawatari S, Akashi K.
, Impaired deformability and association with density distribution of erythrocytes in patients with type 2 diabetes mellitus under treatment.
, Clin Hemorheol Microcirc. , 76, 1, 73-83, 2020.09. |
| 22. |
Yuda J, Odawara J, Minami M, Muta T, Kohno K, Tanimoto K, Eto T, Shima T, Kikushige Y, Kato K, Takenaka K, Iwasaki H, Minami Y, Ohkawa Y, Akashi K, Miyamoto T.
, Tyrosine kinase inhibitors induce alternative spliced BCR-ABLIns35bp variant via inhibition of RNA polymerase II on genomic BCR-ABL., Cancer Sci. , 111, 7, 2361-2373, 2020.07. |
| 23. |
Stumpf PS, Du X, Imanishi H, Kunisaki Y, Semba Y, Noble T, Smith RCG, Rose-Zerili M, West JJ, Oreffo ROC, Farrahi K, Niranjan M, Akashi K, Arai F, MacArthur BD.
, Transfer learning efficiently maps bone marrow cell types from mouse to human using single-cell RNA sequencing.
, Commun Biol.
, 3, 1, 376-736, 2020.12. |
| 24. |
Torisu T, Kawano S, Miyawaki K, Yamamoto H, Ihara Y, Matsuno Y, Torisu K, Sugio T, Sasaki K, Shimakawa T, Kato K, Akashi K, Nakamura S, Kitazono T.
, B cell receptor signaling related to resistance to Helicobacter pylori eradication therapy in gastric diffuse large B cell lymphoma.
, Hematol Oncol.
, 39, 1, 145-147, 2021.02. |
| 25. |
Tsuchihashi K, Kusaba H, Yoshihiro T, Fujiwara T, Setsu N, Endo M, Matsumoto Y, Imajima T, Shinohara Y, Ito M, Yamaga S, Tanoue K, Arimizu K, Ohmura H, Hanamura F, Yamaguchi K, Isobe T, Ariyama H, Nakashima Y, Akashi K, Baba E.
, Eribulin as a first-line treatment for soft tissue sarcoma patients with contraindications for doxorubicin., Sci Rep., 10, 1, 20896-20896, 2020.12. |
| 26. |
Matsuoka S, Hashimoto D, Kadowaki M, Ohigashi H, Hayase E, Yokoyama E, Hasegawa Y, Tateno T, Chen X, Aoyama K, Oka H, Onozawa M, Takeda K, Akashi K, Teshima T.
, Myeloid differentiation factor 88 signaling in donor T cells accelerates graft-versus-host disease.
, Haematologica., 105, 1, 226-234, 2020.01. |
| 27. |
Higashioka K, Ota Y, Maehara T, Moriyama M, Ayano M, Mitoma H, Akahoshi M, Arinobu Y, Horiuchi T, Nakamura S, Akashi K, Niiro H.
, Association of circulating SLAMF7+Tfh1 cells with IgG4 levels in patients with IgG4-related disease., BMC Immunol.
, 21, 1, 31-31, 2020.01. |
| 28. |
Gotoh K, Kunisaki Y, Mizuguchi S, Setoyama D, Hosokawa K, Yao H, Nakashima Y, Yagi M, Uchiumi T, Semba Y, Nogami J, Akashi K, Arai F, Kang D.
, Mitochondrial Protein Synthesis Is Essential for Terminal Differentiation of CD45- TER119-Erythroid and Lymphoid Progenitors.
iScience., iScience., 23, 11, 101654-101654, 2020.10. |
| 29. |
Izutsu K, Kato K, Kiyoi H, Yamamoto G, Shimada K, Akashi K.
, Phase I study of duvelisib in Japanese patients with relapsed or refractory lymphoma., Int J Hematol., 112, 4, 504-509, 2020.10. |
| 30. |
Wang Q, Oryoji D, Mitoma H, Kimoto Y, Koyanagi M, Yokoyama K, Ayano M, Akahoshi M, Arinobu Y, Niiro H, Akashi K, Horiuchi T.
, Methotrexate Enhances Apoptosis of Transmembrane TNF-Expressing Cells Treated With Anti-TNF Agents., Front Immunol. , 11, 2042-2042, 2020.08. |
| 31. |
Nakayama T, Yoshimura M, Higashioka K, Miyawaki K, Ota Y, Ayano M, Kimoto Y, Mitoma H, Ono N, Arinobu Y, Kikukawa M, Yamada H, Akashi K, Horiuchi T, Niiro H.
, Type 1 helper T cells generate CXCL9/10-producing T-bet + effector B cells potentially involved in the pathogenesis of rheumatoid arthritis., Cell Immunol. , 360, 104263-104263, 2021.02. |
| 32. |
Shiratori S, Sugita J, Ota S, Kasahara S, Ishikawa J, Tachibana T, Hayashi Y, Yoshimoto G, Eto T, Iwasaki H, Harada M, Matsuo K, Teshima T; Japan Study Group for Cell Therapy and Transplantation (JSCT).
, Low-dose anti-thymocyte globulin for GVHD prophylaxis in HLA-matched allogeneic peripheral blood stem cell transplantation., Bone Marrow Transplant., 56, 1, 129-136, 2021.01. |
| 33. |
Sugita J, Kamimura T, Ishikawa T, Ota S, Eto T, Kuroha T, Miyazaki Y, Kumagai H, Matsuo K, Akashi K, Taniguchi S, Harada M, Teshima T.
, Reduced dose of posttransplant cyclophosphamide in HLA-haploidentical peripheral blood stem cell transplantation.
, Bone Marrow Transplant., 56, 3, 596-604, 2021.03. |
| 34. |
Yoneshima Y, Kato K, Minami H, Ikeda M, Watanabe H, Yoshimoto G, Miyamoto T, Akashi K, Nakanishi Y, Okamoto I.
, HTLV-1 seropositive patients with lung cancer treated with PD-1 inhibitors.
, Cancer Sci.
, 111, 9, 3395-3396, 2020.09. |
| 35. |
Goto H, Makita S, Kato K, Tokushige K, Fujita T, Akashi K, Izutsu K, Teshima T.
, Efficacy and safety of tisagenlecleucel in Japanese adult patients with relapsed/refractory diffuse large B-cell lymphoma., Int J Clin Oncol. , 25, 9, 1736-1743, 2020.09. |
| 36. |
Kazama R, Miyoshi H, Takeuchi M, Miyawaki K, Nakashima K, Yoshida N, Kawamoto K, Yanagida E, Yamada K, Umeno T, Suzuki T, Kato K, Takizawa J, Seto M, Akashi K, Ohshima K., Combination of CD47 and signal-regulatory protein-α constituting the "don't eat me signal" is a prognostic factor in diffuse large B-cell lymphoma., Cancer Sci., 111, 7, 2608-2619, 2020.07. |
| 37. |
Tsuruta N, Tsuchihashi K, Ohmura H, Yamaguchi K, Ito M, Ariyama H, Kusaba H, Akashi K, Baba E., RNA N6-methyladenosine demethylase FTO regulates PD-L1 expression in colon cancer cells., Biochem Biophys Res Commun., 530, 1, 235-239, 2020.09. |
| 38. |
Tochigi T, Miyamoto T, Hatakeyama K, Sakoda T, Ishihara D, Irifune H, Shima T, Kato K, Maeda T, Ito T, Handa H, Akashi K, Kikushige Y., Aromatase is a novel neo-substrate of cereblon responsible for immunomodulatory drugs-induced thrombocytopenia., Blood., 135, 24, 2146-2158, 2020.06. |
| 39. |
Jinnouchi F, Yamauchi T, Yurino A, Nunomura T, Nakano M, Iwamoto C, Obara T, Miyawaki K, Kikushige Y, Kato K, Maeda T, Miyamoto T, Baba E, Akashi K, Takenaka K., A human SIRPA knock-in xenograft mouse model to study human hematopoietic and cancer stem cells., Blood., 135, 19, 1661-1672, 2020.05. |
| 40. |
Ohmura H, Yamaguchi K, Hanamura F, Ito M, Makiyama A, Uchino K, Shimokawa H, Tamura S, Esaki T, Mitsugi K, Shibata Y, Oda H, Tsuchihashi K, Ariyama H, Kusaba H, Oda Y, Akashi K, Baba E., OX40 and LAG3 are associated with better prognosis in advanced gastric cancer patients treated with anti-programmed death-1 antibody., Br J Cancer., 122, 10, 1507-1517, 2020.03. |
| 41. |
Inokuchi S, Mitoma H, Kawano S, Nakano S, Ayano M, Kimoto Y, Akahoshi M, Arinobu Y, Tsukamoto H, Akashi K, Horiuchi T, Niiro H., Homeostatic Milieu Induces Production of Deoxyribonuclease 1-like 3 from Myeloid Cells., J Immunol., 204, 8, 2088-2097, 2020.03. |
| 42. |
Inokuchi S, Mitoma H, Kawano S, Nakano S, Ayano M, Kimoto Y, Akahoshi M, Arinobu Y, Tsukamoto H, Akashi K, Horiuchi T, Niiro H., Homeostatic Milieu Induces Production of Deoxyribonuclease 1-like 3 from Myeloid Cells., J Immunol., 204, 8, 2088-2097, 2020.03. |
| 43. |
Sakurai M, Okamoto S, Matsumura I, Murakami S, Takizawa M, Waki M, Hirano D, Watanabe-Nakaseko R, Kobayashi N, Iino M, Mitsui H, Ishikawa Y, Takahashi N, Kawaguchi T, Suzuki R, Yamamoto K, Kizaki M, Ohnishi K, Naoe T, Akashi K; New TARGET investigators., Treatment outcomes of chronic-phase chronic myeloid leukemia with resistance and/or intolerance to a 1st-line tyrosine kinase inhibitor in Japan: the results of the New TARGET study 2nd-line., Int J Hematol., 111, 6, 812-825, 2020.03. |
| 44. |
Moriyama S, Fukata M, Kusaba H, Maruyama T, Akashi K., Acute and Chronic Effects of Cancer Drugs on the Cardiovascular System., Heart Fail Clin., 16, 2, 231-241, 2020.04. |
| 45. |
Yamaguchi K, Ito M, Ohmura H, Hanamura F, Nakano M, Tsuchihashi K, Nagai S, Ariyama H, Kusaba H, Yamamoto H, Oda Y, Nakamura M, Akashi K, Baba E., Helper T cell-dominant tertiary lymphoid structures are associated with disease relapse of advanced colorectal cancer., Oncoimmunology., 9, 1, 1724763-1724763, 2020.02. |
| 46. |
Kato K, Takeuchi A, Akashi K, Eto M., Cyclophosphamide-Induced Tolerance in Allogeneic Transplantation: From Basic Studies to Clinical Application., Front Immunol., 10, 3138-3138, 2020.01. |
| 47. |
Ayano M, Arinobu Y, Tsukamoto H, Ota SI, Misaki K, Nishimura K, Kimoto Y, Mitoma H, Akahoshi M, Akashi K, Horiuchi T, Niiro H., Shoulder ultrasound and serum lactate dehydrogenase predict inadequate response to glucocorticoid treatment in patients with polymyalgia rheumatica., Rheumatol Int., 40, 7, 1101-1109, 2020.02. |
| 48. |
Mori Y, Choi I, Yoshimoto G, Muta T, Yamasaki S, Tanimoto K, Kamimura T, Iwasaki H, Ogawa R, Akashi K, Miyamoto T; Fukuoka Blood and Marrow Transplantation Group., Phase I/II study of bortezomib, lenalidomide, and dexamethasone treatment for relapsed and refractory multiple myeloma., Int J Hematol., 111, 5, 673-680, 2020.01. |
| 49. |
Ohmura H, Ito M, Uchino K, Okada C, Tanishima S, Yamada Y, Momosaki S, Komoda M, Kuwayama M, Yamaguchi K, Okumura Y, Nakano M, Tsuchihashi K, Isobe T, Ariyama H, Kusaba H, Oda Y, Akashi K, Baba E., Methylation of drug resistance-related genes in chemotherapy-sensitive Epstein-Barr virus-associated gastric cancer., FEBS Open Bio., 10, 1, 147-157, 2020.01. |
| 50. |
Miyawaki K, Kato K, Sugio T, Sasaki K, Miyoshi H, Semba Y, Kikushige Y, Mori Y, Kunisaki Y, Iwasaki H, Miyamoto T, Kuo FC, Aster JC, Ohshima K, Maeda T, Akashi K., A Germinal Center-Associated Microenvironmental Signature Reflects Malignant Phenotype and Outcome of DLBCL., Blood Adv., 10.1182/bloodadvances.2021004618., 6, 7, 2388-2402, 2022.04. |
| 51. |
Sasaki K, Yamauchi T, Semba Y, Nogami J, Imanaga H, Terasaki T, Nakao F, Akahane K, Inukai T, Verhoeyen E, Akashi K, Maeda T., Genome-wide CRISPR-Cas9 screen identifies rationally designed combination therapies for CRLF2-rearranged Ph-like ALL, Blood, 10.1182/blood.2021012976., 139, 5, 748-760, 2022.03. |
| 52. |
Jinnouchi F, Yamauchi T, Yurino A, Nunomura T, Miyawaki K, Kikushige Y, Kato K, Maeda T, Miyamoto T, Baba E, Akashi K, Takenaka K., Establishment of a human SIRPA knock-in xenograft mouse model to study human hematopoietic and cancer stem cells., Blood
, 10.1182/blood.2019002194., 135, 19, 1661-1672, 2020.05. |
| 53. |
Uryu H, Hashimoto D, Kato K, Hayase E, Matsuoka S, Ogasawara R, Takahashi S, Maeda Y, Iwasaki H, Miyamoto T, Saijo S, Iwakura Y, Hill GR, Akashi K, Teshima T., α-Mannan induces Th17-mediated pulmonary graft-versus-host disease in mice., Blood, 10.1182/blood-2014-12-615781, 125, 19, 3014-3023, 2015.05. |
| 54. |
koichi akashi, Contribution of bone marrow-derived hematopoietic stem/progenitor cells to the generation of donor-marker(+) cardiomyocytes in vivo., PLoS One 8, 8, e62506, 2013.05. |
| 55. |
koichi akashi, Antibiotic rotation for febrile neutropenic patients with hematological malignancies: clinical significance of antibiotic heterogeneity., PLoS One 8, 8, e54190, 2013.01. |
| 56. |
koichi akashi, The BALB/c-specific polymorphic SIRPA enhances its affinity for human CD47, inhibiting phagocytosis against human cells to promote xenogeneic engraftment., Exp Hematol, 42, 163-171, 2013.11. |
| 57. |
Yoshimoto G, Miyamoto T, Tabrizi SJ, Iino T, Rocnik JL, Kikushige Y, Mori Y, Shima T, Iwasaki H, Takenaka K, Nagafuji K, Mizuno SI, Niiro H, Gilliland GD, Akashi K., FLT3-ITD upregulates MCL-1 to promote survival of stem cells in acute myeloid leukemia via FLT3-ITD-specific STAT5 activation., Blood, 114, 24, 5034-5043, 2010.10. |
| 58. |
Kohno K, Nagafuji K, Tsukamoto H, Horiuchi T, Takase K, Aoki K, Henzan H, Kamezaki K, Takenaka K, Miyamoto T, Teshima T, Harada M, Akashi K., Infectious complications in patients receiving autologous CD34-selected hematopoietic stem cell transplantation for severe autoimmune diseases., Transplant Infect Dis, 11, 4, 318-323, 2009.10. |
| 59. |
Mori Y, Iwasaki H, Kohno K, Yoshimoto G, Kikushige Y, Okeda A, Uike N, Niiro H, Takenaka K, Nagafuji K, Miyamoto T, Harada M, Takatsu K, Akashi K., Identification of the human eosinophil lineage-committed progenitor: revision of phenotypic definition of the human common myeloid progenitor., J Exp Med, 2009.10. |
| 60. |
Koyama, M., D. Hashimoto, K. Aoyama, K.I. Matsuoka, K. Karube, H. Niiro, M. Harada, M. Tanimoto, K. Akashi, and T. Teshima. , Plasmacytoid dendritic cells prime alloreactive T cells to mediate graft-versus-host disease as antigen-presenting cells. , Blood , 26;113(9):2088-95., 2009.02. |
| 61. |
Tabrizi, S.J., H. Niiro, M. Masui, G. Yoshimoto, T. Iino, Y. Kikushige, T. Wakasaki, E. Baba, S. Shimoda, T. Miyamoto, T. Hara, and K. Akashi. , T cell leukemia/lymphoma 1 and galectin-1 regulate survival/cell death pathways in human naive and IgM+ memory B cells through altering balances in Bcl-2 family proteins. , J Immunol, 182:1490-1499, 2009.02. |
| 62. |
Mori, Y., H. Iwasaki, K. Kohno, G. Yoshimoto, Y. Kikushige, A. Okeda, N. Uike, H. Niiro, K. Takenaka, K. Nagafuji, T. Miyamoto, M. Harada, K. Takatsu, and K. Akashi., Identification of the human eosinophil lineage-committed progenitor: revision of phenotypic definition of the human common myeloid progenitor., J Exp Med , 206:183-193, , 2009.01. |
| 63. |
Kikushige Y, Yoshimoto G, Miyamoto T, Iino T, Mori Y, Iwasaki H, Niiro H, Takenaka K, Nagafuji K, Harada M, Ishikawa F, Akashi K. , Human Flt3 is expressed at the hematopoietic stem cell and the granulocyte/macrophage progenitor stages to maintain cell survival., J Immunol , 108:7348-7367., 2008.06. |
| 64. |
Cantor AB, Iwasaki H, Arinobu Y, Moran TB, Shigematsu H, Sullivan MR, Akashi K, Orkin SH. , Antagonism of FOG-1 and GATA foctors in fate choice for the mast cell lineage. , J Exp Med , 2008; 205:611-624., 2008.03. |
| 65. |
Ishikawa F, Yoshida S, Saito Y, Hijikata A, Kitamura H, Tanaka S, Nakamura R, Tanaka T, Tomiyama H, Saito N, Fukata M, Miyamoto T, Lyons B, Ohshima K, Uchida N, Taniguchi S, Ohara O, Akashi K, Harada M, Shultz LD:, Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region., Nat Biotech, 2007.11. |
| 66. |
Arinobu Y, Mizuno S-I, Chong Y, Shigematsu H, Iino T, Iwasaki H, Graf T, Mayfield R, Chan S, Kastner P, Akashi K: , Reciprocal activation of GATA-1 and PU.1 marks initial specification of hematopoietic stem cells into myelo-erythroid and myelo-lymphoid lineages., Cell Stem Cell , 1, 416-27,, 2007.10. |
| 67. |
Ishikawa F, Niiro H, Iino T, Yoshida S, Saito N, Onohara S, Miyamoto T, Minagawa H, Fujii SI, Shultz LD, Harada M, Akashi K:
, The developmental program of human dendritic cells is operated independently of conventional myeloid and lymphoid pathways.
, Blood. , in press., 2007.07. |
| 68. |
Feinberg MW, Wara AK, Cao Z, Lebedeva MA, Rosenbauer F, Iwasaki H, Hirai H, Katz JP, Haspel RL, Gray S, Akashi K, Segre J, Kaestner KH, Tenen DG, Jain MK: , The Kruppel-like factor KLF4 is a critical regulator of monocyte differentiation. , EMBO J , 26, 4138-48, 2007.09. |
| 69. |
Yoshida K, Yonemitsu Y, Tanaka S, Yoshida S, Shibata S, Kondo H, Okano S, Ishikawa F, Akashi K, Inoue M, Hasegawa M, Sueishi K:
, In vivo repopulation of cytoplasmically gene transferred hematopoietic cells by temperature-sensitive mutant of recombinant Sendai viral vector.
, Biochem Biophys Res Commun , 361, 811-6, 2007.09. |
| 70. |
Raffel GD, Mercher T, Shigematsu H, Williams IR, Cullen DE, Akashi K, Bernard OA, Gilliland DG:
, Ott1(Rbm15) has pleiotropic roles in hematopoietic development.
, Proc Natl Acad Sci USA , 104, 6001-6, 2007.04. |
| 71. |
Maeda T, Merghoub T, Hobbs RM, Dong L, Maeda M, Zakrzewski J, van den Brink MR, Zelent A, Shigematsu H, Akashi K, Teruya J, Cattoretti G, Pandolfi PP:
, Regulation of B versus T lymphoid lineage fate decision by the proto-oncogene LRF.
, Science , 316, 860-6, 2007.05. |
| 72. |
Mori Y, Yoshimoto G, Kumano T, Miyamoto T, Iino T, Takenaka K, Iwasaki H, Harada N, Kinukawa N, Nagafuji K, Teshima T, Shimoda K, Akashi K, Harada M:
, Distinctive Expression of Myelomonocytic markers and down-regulation of CD34 in acute myelogenous leukaemia with FLT3 tandem duplication and nucleophosmin mutation.
, Eur J Haematol, 79, 17-24, 2007.07. |
| 73. |
Alcaide P, Jones TG, Lord GM, Glimcher LH, Hallgren J, Akashi K, Patterson A, Gurish MA, Luscinskas FW:
, Dendritic cell expression of the transcription factor T-bet regulates mast cell progenitor homing to mucosal tissue.
, J Exp Med, 204, 431-9, 2007.02. |
| 74. |
Iwasaki H, Mizuno S, Arinobu Y, Ozawa H, Mori Y, Shigematsu H, Takatsu K, Tenen DG and Akashi K:
, The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages.
, Genes Dev , 20, 3010-21, 2006.11. |
| 75. |
Chan IT, Kutok JL, Williams IR, Cohen S, Moore S, Shigematsu H, Ley TJ, Akashi K, Le Beau MM, Gilliland DG:
, Oncogenic K-ras cooperates with PML-RAR alpha to induce an acute promyelocytic leukemia-like disease.
, Blood, 108, 1708-15, 2006.05. |
| 76. |
Hirai H, Zhang P, Dayaram T, Hetherington CJ, Mizuno S, Imanishi J, Akashi K and Tenen DG:
, C/EBPbeta is required for 'emergency' granulopoiesis.
, Nat Immunol, 7, 732-9 , 2006.06. |
| 77. |
Rosenbauer F, Owens BM, Yu L, Tumang JR, Steidl U, Kutok JL, Clayton LK, Wagner K, Scheller M, Iwasaki H, Liu C, Hackanson B, Akashi K, Leutz A, Rothstein TL, Plass C, and Tenen DG:
, Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1.
, Nat Genet , 38, 27-37, 2006.11. |
| 78. |
Sicinska E, Lee YM, Gits J, Shigematsu H, Yu Q, Rebel VI, Geng Y, Marshall CJ, Akashi K, Dorfman DM, Touw IP, Sicinski P.
, Essential role for cyclin d3 in granulocyte colony-stimulating factor-driven expansion of neutrophil granulocytes. , Mol Cell Biol , 26, 8052-60, 2006.09. |
| 79. |
Arinobu Y, Iwasaki H, Gurish MF, Mizuno S, Shigematsu H, Ozawa H, Tenen DG, Austen KF, Akashi K:
, Developmental checkpoints of the basophil/mast cell lineages in adult murine hematopoiesis. , Proc Natl Acad Sci USA , 10.1073/pnas.0509148102, 102, 50, 18105-18110, 102, 18105-10, 2005.12. |
| 80. |
Mohi MG, Williams IR, Dearolf CR, Chan G, Kutok JL, Cohen S, Morgan K, Boulton C, Shigematsu H, Keilhack H, Akashi K, Gilliland DG, Neel BG: , Prognostic, therapeutic,and mechanistic implications of a mouse model of leukemia evoked by Shp2 (PTPN11) mutations.
, Cancer Cell , 7,179-191, 2005.02. |
| 81. |
Growney JD, Shigematsu H, Li Z, Lee BH, Adelsperger J, Rowan R, Curley DP, Kutok JL, Akashi K, Williams IR, Speck NA, Gilliland DG: , Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype.
, Blood , 106, 494-504, 2005.03. |
| 82. |
Ishikawa F, Yasukawa M, Lyons B, Yoshida S, Miyamoto T, Yoshimoto G, Watanabe T, Akashi K, Shultz LD, Harada M:
, Development of functional human blood and immune systems in NOD/SCID/IL2 receptor (gamma) chain (null) mice.
, Blood , 10.1182/blood-2005-02-0516, 106, 5, 1565-1573, 106, 1565-1573, 2005.05. |
| 83. |
Kawano N, Ishikawa F, Shimoda K, Yasukawa M, Nagafuji K, Miyamoto T, Baba E, Tanaka T, Yamasaki S, Gondo H, Otsuka T, Ohshima K, Shultz LD, Akashi K, Harada M:, Efficient engraftment of primary adult T-cell leukemia cells in newborn NOD/SCID/beta2-microglobulin(null) mice. , Leukemia , 10.1038/sj.leu.2403829, 19, 8, 1384-1390, 19, 1384-1390, 2005.08. |
| 84. |
Iwasaki H,Iwasaki-Arai J,Somoza C,Duprez EA,Geary K,Zhang P,Dayaram T,Fenyus M,Huettner CS,Murray R,Tenen DG,and Akashi K., Distinct and indispensable roles of PU.1 in maintenance of stem cells and their differentiaation., Blood, 106, 1590-1600, 2005.05. |
| 85. |
Iwasaki H, Mizuno S, Mayfield R, Shigematsu H, Arinobu Y, Seed B, Gurish MF, Takatsu K,and Akashi K., Identification of eosinophil lineage-committed progenitors in the murine bone marrow., Journal of Experimental Medicine, 10.1084/jem.20050548, 201, 12, 1891-1897, 201:1891-7., 2005.01. |
| 86. |
Opferman JT, Iwasaki H, Ong CC, Suh H, Akashi K, and Korsmeyer S., Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells., Science, 307:1101-04., 2005.01. |
| 87. |
Huntly BJP,Shigematsu H,Deguchi K,Lee BH,Mizuno S,Duclos N,Rowan R,Amaral S,Curley D,Williams IR,Akashi K,and Gilliland DG., Moz-TIF2 but not BCR-ABL confers properties of leukaemic stem cells to committed murine hematopoietic progenitors., Cancer Cell, 6:587-96., 2004.01. |
| 88. |
Yan M,Burel SA,Peterson LF,Kanabe E,Iwasaki H,Boyapati A,Hines R,Akashi K,and Zhang DE., Deletion of an AML1-ETO C-terminal NcoR/SMRT-interacting region strongly induces leukemia development., Proc.Natl.Acad.Sci.USA, 101:17186-91., 2004.01. |
| 89. |
Kozar K, Ciemerych MA, Rebel VI, Shigematsu H, Zagozdzon A, Sicinska E, Geng Y, Yu Q, Bhattacharya S, Bronson RT, Akashi K and Sicinski P, Mouse development and cell proliferation in the absence of D-cyclins., Cell, 118:477-91, 2004.01. |
| 90. |
Shigematsu H, Reizis B, Iwasaki H, Mizuno S, Hu D, Traver D, Leder P, Sakaguchi N and Akashi K., Plasmacytoid dendritic cells activate lymphoid-specific genetic programs irrespective of their cellular origin., Immunity, 10.1016/j.immuni.2004.06.011, 21, 1, 43-53, 21:43-53, 2004.01. |
| 91. |
Rosenbauer F,Wagner K,Kutok JL,Iwasaki H,Le Beau MM,Okuno Y,Akashi K,Fiering S,Tenen DJ., Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor,PU.1., Nature Genetics, 36:624-30., 2004.01. |
| 92. |
Iwasaki H, Mizuno S, Wells RA, Watanabe S, and Akashi K., GATA-1 converts lymphoid and myelomonocytic progenitors into the megakaryocyte/erythrocyte lineages., Immunity, 19:451-62, 2003.01. |
| 93. |
Iwasaki-Arai J, Iwasaki H, Miyamoto T, Watanabe S, and Akashi K., Enforced GM-CSF signals in lymphoid-committed progenitors do not support lymphoid development, but instruct lymphoid to myelomonocytic lineage conversion., Journal of Experimental Medicine, 10.1084/jem.20021843, 197, 10, 1311-1322, 197:1311-22, 2003.01. |
| 94. |
Ye M,Iwasaki H,Laiosa CV,Stadtfeld M,Heck S,Clausen B,Akashi K and Graf T., Hematopoietic stem cells expressing the myeloid lysozyme gene retain long-term,multilineage repopulation potential., Immunity, 19:689-99., 2003.01. |
| 95. |
Jaiswal S,Traver D,Miyamoto T,Akashi K,Lagasse E,and Weissman IL., Expression of BCR/ABL and BCL-2 in myeloid progenitors leads to myeloid leukemias., Proc.Natl.Acad.Sci.USA, 100:10002-7., 2003.01. |
| 96. |
Akashi K, He X, Chen J, Iwasaki H, Niu C, Steenhard B, Zhang J, Haug J, and Li L., Transcriptionalaccessibility for multilineage programs in hematopoietic stem and progenitor cells., Blood, 101:383-9, 2003.01. |
| 97. |
Manz M, Miyamoto T, Akashi K and Weissman IL., Prospective isolation of human clonogenic common myeloid progenitors., Proc. Natl. Acad. Sci. USA, 99:11872-7, 2002.01. |
| 98. |
Miyamoto T, Iwasaki H, Reides B, Ye M, Graf T, Weissman IL and Akashi K., Myeloid or lymphoid promiscuity as a critical step in hematopoietic lineage commitment., Developmental Cell, 3:137-47, 2002.01. |
| 99. |
Nakorn TN, Traver D, Weissman IL and Akashi K., Myeloerythroid-restricted progenitors can alone provide radioprotection and the majority of day 8 CFU-S., Journal of Clinical Investigation, 109:1579-85, 2002.01. |
| 100. |
Okuno Y, Iwasaki H, Huettner CS, Radomska HS, Gonzalez DA, Tenen DG, and Akashi K., Differential regulation of the human and murine CD34 genes in hematopoietic stem cells., Proc Natl Acad Sci USA, 99:6246-51, 2002.01. |
| 101. |
Yuan Y,Zhou L,Miyamoto T,Harakawa N,Hetherington CJ,Burel S,Lagasse E,Weissman IL,Akashi K,and Zhang DE., AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations., Proc.Natl.Acad.Sci.USA, 98:10398-403., 2001.01. |
| 102. |
Mebius RE,Miyamoto T,Christensen J,Domen J,Cupedo T,Weissman IL,and Akashi K., The fetal liver counterpart of adult common lymphoid progenitors gives rise to all lymphoid lineages, CD45+CD4+CD3-cells,as well as macrophages., Journal of Immunology, 166:6593-6601., 2001.01. |
| 103. |
Manz M,Traver D,Miyamoto T,Weissman IL,and Akashi K., Dendritic Cell potentials in early from lymphoid and myeloid hematopoiesis., Blood, 97:3333-41, 2001.01. |
| 104. |
Traver D, Akashi K, Manz M, Merad M, Miyamoto M, Engleman EG, and Weissman IL., Development of CD8a-positive dendritic cells from a common myeloid progenitor., Science, 290:2152-4, 2000.01. |
| 105. |
Kondo M, Scherer DC, Miyamoto T, King AG, Akashi K, Sugamura K, and Weissman IL., Cell fate conversion of lymphoid committed progenitors by instructive actions of cytokines., Nature, 407:383-6, 2000.01. |
| 106. |
Miyamoto T, Weissman IL, and Akashi K., AML1/ETO-expressing non-leukemic hematopoietic stem cells in acute myelogenous leukemia with 8;21 translocation., Proc. Natl. Acad. Sci. USA, 97:7521-26, 2000.01. |
| 107. |
Akashi K, Traver D, Miyamoto T, and Weissman IL., A clonogenic common myeloid progenitor that gives rise to all myeloid lineages., Nature, 404:193-7, 2000.01. |
| 108. |
Traver D, Akashi K, Weissman IL, and Lagasse E., Mice defective in two apoptosis pathways in the myeloid lineage develop acute myeloblastic leukemia., Immunity, 9:47-57, 1998.01. |
| 109. |
Akashi K, Kondo M, and Weissman IL., Two distinct pathway of positive selection for thymocytes, Proc. Natl. Acad. Sci. USA, 95:2486-91, 1998.01. |
| 110. |
Kondo M, Weissman IL, and Akashi K., Identification of clonogenic common lymphoid progenitors in mouse bone marrow., Cell, 91:661-72, 1997.01. |
| 111. |
Kondo M, Akashi K, Domen J, Sugamura K, and Weissman IL, Bcl-2 rescues T lymphopoiesis but not B or NK cell development in common cytokine receptor g chain-deficient mice., Immunity, 7:155-62, 1997.01. |
| 112. |
Akashi K, Kondo M, von Freeden-Jeffry U, Murray R, and Weissman IL., Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice., Cell, 89:1033-41, 1997.01. |
| 113. |
Morrison S, Waldtze A, Akashi K, Gilberson A, and Weissman IL, The aging of hemetopoietic stem cell, Nature Medicine, 2:1011-6, 1996.01. |
| 114. |
Akashi K, Mizuno S, Harada M, Takamatsu Y, Tamura K, Shibuya T, Gondo H, Hayashi S, Okamura T, Niho Y., Involvement of interferon-g and macrophage colony-stimulating factor in pathogenesis of hemophagocytic lymphohistiocytosis in adults., British Journal of Haematology, 10.1111/j.1365-2141.1994.tb04905.x, 87, 2, 243-250, 87:243-50, 1994.01. |
| 115. |
Akashi K, Shibuya T, Harada M, Takamatsu Y, Uike N, Eto T, Niho Y., Interleukin-4 suppresses the spontaneous growth of chronic myelomonocytic leukemia cells, Journal of Clinical Investigation, 10.1172/JCI115281, 88, 1, 223-230, 88:223-30, 1991.01. |
| 116. |
Akashi K, Eizuru Y, Sumiyoshi Y, Minematsu T, Hara S, Harada M, Niho Y, Kikuchi M, Minamishima Y., Severe infectious mononucleosis-like syndrome and a primary human herpesvirus-6 infection in an adult., New England Journal of Medicine, 10.1056/NEJM199307153290304, 329, 3, 168-171, 329:168-71, 1993.01. |
| 117. |
Akashi K, and Weissman IL, The c-Kit-positive maturation pathway in mouse T cell development: lineage and selection, Immunity, 10.1016/S1074-7613(00)80491-4, 5, 2, 147-161, 5:147-61, 1996.01. |
