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Tomonori Somamoto Last modified date:2019.06.13

Associate Professor / Marine Biological Chemistry
Department of Bioscience and Biotechnology
Faculty of Agriculture


Graduate School
Undergraduate School


E-Mail
Homepage
http://www.agr.kyushu-u.ac.jp/biosci-biotech/suizoku/
Phone
092-642-2895
Fax
092-642-2897
Academic Degree
PhD
Field of Specialization
Fish Immunology
Research
Research Interests
  • The study of cell-mediated immunity in fish
    keyword : cell-mediated immunity, virus, ginbuna crucian carp
    2003.04.
  • Prevention of fish disease using affinity silk
    keyword : affinity silk, fish disease, prophylaxis
    2016.04~2019.03.
  • Immune systems of rag-1-deficient zebrafish against bacterial and viral infection.
    keyword : zebrafish RAG-1-deficient immune system infection
    2011.04~2014.03.
  • Development of prophylaxis strategy against infectious disease in koi carp employing hen egg antibody (IgY)
    keyword : IgY, prophylaxis, koi caro.
    2008.05.
Academic Activities
Books
1. 中尾 実樹, 杣本 智軌, The evolution of complement system functions and pathways in vertebrates. in THE EVOLUTION OF THE IMMUNE SYSTEM: A BALANCE BETWEEN CONSERVATION AND DIVERSITY,, Elsevier, chapter 6,152-171, 2016.07.
Reports
1. Somamoto T, Koppang E.O., Fischer U., Antiviral functions of CD8+ cytotoxic T cells in teleost fish., Developmental and Comparative Immunology, 43: 197–204., 2014.04.
2. Nakanishi T, Toda H, Shibasaki Y, Somamoto T., Cytotoxic T cells in teleost fish., Developmental and Comparative Immunology, 35:1317-23., 2011.12.
3. Uwe Fischer, Katrin Utke, Tomonori Somamoto, Bernd Köllner, Mitsuru Ototake, Teruyuki Nakanishi, Cytotoxic activities of fish leucocytes, Fish & Shellfish Immunology, 20,209-26., 2006.02.
4. T. Nakanishi, U. Fischer, J.M.Dijkststra, Hasegawa, T. Somamoto, N. Okamoto, and M. Ototake., Cytotoxic T-cell function in fish., Developmental and Comparative Immunology, 26,131-139., 2002.01.
Papers
1. Tajimi S, Kondo M, Nakanishi T, Nagasawa T, Nakao M, Somamoto T., Generation of virus-specific CD8+ T cells by vaccination with inactivated virus in the intestine of ginbuna crucian carp., Developmental and Comparative Immunology, doi: 10.1016/j.dci.2018.12.009., 93, 37-44, 2019.03.
2. Somamoto T, Maruyama S, Nagasawa T, Nakao M, Sato A, Hatta H, Sato M, Murakami-Yamaguchi Y, Kizu-Mori K, Hirakawa Y, Narita H. , Development of anti-atypical Aeromonas salmonicida monoclonal antibodies for diagnosis of new ulcer disease in koi carp. , Fish Pathology, 53, 1, 36-39, 2018.03.
3. Tokunaga Y, Shirouzu M, Sugahara R, Yoshiura Y, Kiryu Y, Ototake M, Nagasawa T, Somamoto T, Nakao M, Comprehensive validation of T- and B-cell deficiency in rag1-null zebrafish: Implication for the robust innate defense mechanisms of teleosts., Scientific Reports., 2017, 7, 7536, 2017.08.
4. Nur I, Abdelkhalek NK, Motobe S, Nakamura R, Tsujikura M, Somamoto T, Nakao M, Functional analysis of membrane-bound complement regulatory protein on T-cell immune response in ginbuna crucian carp., Molecular Immunology , doi: 10.1016/j.molimm.2015.11.010., 70, 1-7, 2016.02.
5. Nagasawa T, Somamoto T, Nakao M, Carp thrombocyte phagocytosis requires activation factors secreted from other leukocytes, Developmental and Comparative Immunology, 52, 107 -111, 2015.05.
6. Somamoto T, Miura Y, Nakanishi T, Nakao M, Local and systemic adaptive immune responses toward viral infection via gills in ginbuna crucian carp, Developmental and Comparative Immunology, 52, 1, 81-87, 2015.04.
7. Gan H, He H, Sato A, Hatta H, Nakao M, Somamoto T, Ulcer disease prophylaxis in koi carp by bath immersion with chicken egg yolk containing anti-Aeromonas salmonicida IgY. , Research in Veterinary Science, doi:10.1016/j.rvsc.2015.01.016, 99, 82-86, 2015.02.
8. Tsujikura M, Nagasawa T, Ichiki S, Nakamura R, Somamoto T, Nakao M, A CD46-like Molecule Functional in Teleost Fish Represents an Ancestral Form of Membrane-Bound Regulators of Complement Activation. , Journal of Immunology, doi: 10.4049/jimmunol.1303179, 194, 262-272, 2015.01.
9. Nagasawa T, Nakayasu C, Rieger AM, Barreda DR, Somamoto T, Nakao M, Phagocytosis by thrombocytes is a conserved innate immune mechanism in lower vertebrates. , Frontiers in Immunology, doi: 10.3389/fimmu.2014.00445, 5, 445, 2014.09.
10. Tomonori Somamoto, Masakazu Kondo, Teruyuki Nakanishi, Miki Nakao, Helper function of CD4+ lymphocytes in antiviral immunity in ginbuna crucian carp, Carassius auratus langsdorfii. , Developmental and Comparative Immunology, doi: 10.1016/j.dci.2013.12.008, 44, 111-115, 2014.05.
11. Nur I, Tsujikura M, Somamoto T, Nakao M, Molecular characterization and expression analysis of three membrane-bound complement regulatory protein isoforms in the ginbuna crucian carp Carassius auratus langsdorfii., Fish and Shellfish Immunology, doi: 10.1016/j.fsi.2013.08.002., 35, 1333-1337, 2013.10.
12. Somamoto T, Nakanishi T, Nakao M, Identification of anti-viral cytotoxic effector cells in the ginbuna crucian carp, Carassius auratus langsdorfii., Developmental and Comparative Immunology , 39, 370–377, 2013.05.
13. Sameshima S, Nakao M, Somamoto T. , Diversity of CD2 subfamily receptors in cyprinid fishes., Result Immunol, 2, 25-34, 2012.02.
14. Urabe S, Somamoto T, Sameshima S, Unoki-Kato Y, Nakanishi T, Nakao M., Molecular characterization of MHC class I and beta-2 microglobulin in a clonal strain of ginbuna crucian carp, Carassius auratus langsdorfii., Fish Shellfish Immunol., 31, 3, 469-74. , 2011.09.
15. Toda H, Saito Y, Koike T, Takizawa F, Araki K, Yabu T, Somamoto T, Suetake H, Suzuki Y, Ototake M, Moritomo T, Nakanishi T., Conservation of characteristics and functions of CD4 positive lymphocytes in a teleost fish., Dev Comp Immunol. , 35, 650-60., 2011.03.
16. Tomonori Somamoto, Nobuaki Okamoto, Teruyuki Nakanishi, Mitsuru Ototake, and Miki Nakao,, In vitro generation of viral-antigen dependent cytotoxic T-cells from ginbuna crucian carp, Carassius auratus langsdorfii, Virology, 20, 389, 26-33., 2009.06.
17. Seiko Nonaka, Tomonori Somamoto, Yoko Kato-Unoki, Mitsuru Ototake, Teruyuki Nakanishi, Miki Nakao, Molecular cloning of CD4 from ginbuna crucian carp, Carassius auratus langsdorfii, Fisheries Science, 74: 341-346., 2008.04.
18. Tomonori Somamoto, Yasutoshi Yoshiura, Atsushi Sato, Miki Nakao, Teruyuki Nakanishi, Nobuaki Okamoto, Mitsuru Ototake, Expression profiles of TCRβ and CD8α mRNA correlate with virus-specific cell-mediated cytotoxic activity in ginbuna crucian carp, Virology, 348: 370-377, 2006.05.
19. J.M. Dijkstra, T. Somamoto, L. Moore, I. Hordvik, M. Ototake, and U. Fischer., Identification and characterization of a second CD4-like gene in teleost fish., Molecular Immunology, 43: 410-419., 2006.02.
20. Tomonori Somamoto, Yasutoshi Yoshiura, Teruyuki Nakanishi, Mitsuru Ototake., Molecular cloning and characterization of two types of CD8α from ginbuna crucian carp, Carassius auratus langsdorfii., Developmental and Comparative Immunology, 29,693-702, 2005.07.
21. Tomonori Somamoto, Atsushi Sato, Teruyuki Nakanishi, Mitsuru Ototake, and Nobuaki Okamoto., Specific cytotoxic activity generated by mixed leucocyte culture in ginbuna crucian carp., Fish & Shellfish Immunology, 17,187-191, 2004.08.
22. Tomonori Somamoto, Teruyuki Nakanishi, and Nobuaki Okamoto., Role of specific cell-mediated cytotoxicity in protecting fish from viral infections., Virology, 297,120-127, 2002.03.
Presentations
1. Seisuke Tajimi, Tomonori Somamoto, Teruyuki Nakanishi, Miki Nakao, Induction of T cell immunity by intentional immunization with inactivated virus in ginbuna crucain carp, 13th Congress of the International Society for Developmental and Comparative Immunology, 2015.06.
2. Indriyani Nur, Hikari Harada, Ryota Nakamura, Masakazu Tsujikura, Tomonori Somamoto, Miki Nakao, Characterizations of membrane-bound complement regulatory protein in Ginbuna Crucian Carp Carassius auratus langsdorfii, 日本比較免疫学会, 2013.08.