|Asayama Yoshiki||Last modified date：2012.8.13|
Department of Clinical Radiology Kyushu University.
Field of Specialization
Radiological Imaging of hepatic tumor
- Distinguishing intrahepatic cholangiocarcinoma from poorly differentiated hepatocellular carcinoma with gadoxetic acid-enhanced MRI
keyword : intrahepatic cholangiocarcinoma, hepatocellular carcinoma, MRI, gadoxetic acid
- Imaginf findings of the liver tumor originating from hepatic progenitor cell
keyword : hepatic progenitor cell, CT, MRI
- CT-guided Radiofrequency ablation of osteoid osteoma
keyword : osteoid osteoma, CT radiofrequency ablation
- The differentiation of well differentiated hepatocellular carcinoma from borderline lesion using EOB-MRI
keyword : liver MRI hepatocellular carcinoma EOB
- Radiologic imaging findings of liver tumors
keyword : liver CT, MRI, angiography
- Imaging findings of cholangiolocellular carcinoma
keyword : cholangiolocellular carcinoma, CT, MRI
|1.||Purpose: The aim of this study was to reveal the relationship between intratumoral uptake of gadoliniumethoxylbenzyldiethylenetriaminepentaacetic acid (Gd-EOB-DTPA) of hepatocellular carcinoma (HCC) in the hepatobiliary phase and pathological features.
Materials and Methods: Sixty HCC nodules were confirmed at pathology in 56 patients who had undergone dynamic MRI. T1-weighted 3D gradient echo sequences before and 20 minutes (hepatobiliary phase) after the injection of Gd-EOB-DTPA were performed. Uptake of Gd-EOB-DTPA was defined as an increase in signal intensity in the hepatobiliary phase compared with the precontrast scan. All surgical specimens were fixed with formalin and then digitally photographed. The relationship between Gd-EOB-DTPA uptake and histological findings, including a macroscopic greenish area, was examined.
Results: MR images showed uptake of Gd-EOB-DTPA in twenty-two nodules. Histological findings indicated twenty-six nodules contained a greenish area. There is a significant correlation between HCC showing Gd-EOB-DTPA uptake and the presence of a greenish area (p < 0.001). On a nodule-by-nodule basis, more than two-thirds of the area of Gd-EOB DTPA uptake coincides with the greenish part in only 12 of 22 lesions (54.5%). More than two-thirds of the greenish area coincided with that of Gd-EOB-DTPA uptake in only 10 of 26 cases (38.5%).