Kyushu University Academic Staff Educational and Research Activities Database
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Makoto Kubo Last modified date:2019.06.24

Lecturer / Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University
Breast Surgery (1)
Kyushu University Hospital


Graduate School
Undergraduate School
Other Organization


Homepage
http://www.med.kyushu-u.ac.jp/surgery1
Academic Degree
MD, PhD
Country of degree conferring institution (Overseas)
No
Field of Specialization
Breast surgery and oncology
Total Priod of education and research career in the foreign country
02years00months
Outline Activities
We perform medical examination and treatment (diagnosis / surgery / oncological treatment, etc.) for the patient with breast cancer and conduct translational research about the breast cancer from the approach of surgical and clinical oncology. Also, we try to upbring the specialists for the sake of corresponding to the rapid increase of patients with breast cancer. Moreover, we attend at the patients' associations, and we are consulted and work on enlightenment.
Research
Research Interests
  • Diagnosis and monitoring for treatment with using cell free DNA
    keyword : Cell free DNA
    2019.01~2024.12.
  • Cancer genome medicine
    keyword : Cancer genome medicine
    2018.04~2021.03.
  • The combination of PD-L1 expression and decreased tumor-infiltrating lymphocytes is associated with a poor prognosis in triple-negative breast cancer.
    keyword : PD-L1
    2015.06~2017.06.
  • BRCAness in triple negative breast cancer
    keyword : BRCAness
    2014.04~2016.05.
  • Hereditary Breast and Ovarian Cancer Syndrome
    keyword : Hereditary Breast Cancer
    2013.04~2014.05.
  • 1.Breast Cancer Stem Cells
    2.Gene Profiling of Breast Cancer
    3.Endoscopic Breast Surgery
    keyword : Breast cancer
    2003.09~2014.121. We sort CD24-/lowCD44+ cells as stem-like cells of the breast cancer and analyze its signaling. Also, we investigate the therapeutic directionality of the drug-resistant or triple negative breast cancer by determining the characteristics of cancer stem cells. 2. We perform gene profiling of breast carcinomas using resected samples and store genetic samples . We analyze particularly juvenile breast cancers and make a base of the therapy choice. 3. We choose and produce devices to establish the methods of endoscopic surgery for patients with primary breast cancer. .
Current and Past Project
  • Our goal is to construct an examination system in Japan and analyze genetic mutations using multiーplex panel examination, a comprehensive cancer-related gene analysis tool by NGS.
  • Real practise and prognosis based on subtypes in breast cancer.
  • We build the mutual and stable relationship between the two countries while applying the Internet technology.
Academic Activities
Membership in Academic Society
  • Japanese Cancer Association
  • Kyushu Associations of Surgery, Pediatric Surgery, and Endocrine Surgery
  • Japan Society of Clinical Oncology
  • Japan Breast Cancer Society
  • Japan Surgical Society
Awards
  • Target therapy for triple negative breast cancer
  • Five programs provided scholarships designed to promote the education and professional development of early-career scientists who are
    actively pursuing research in breast cancer by facilitating their attendance at SABCS.
  • Hedgehog signaling pathway is a new therapeutic target for patients with breast cancer.
Educational
Educational Activities
Lecture 1: "Hereditary tumors" for 4-degree students in Medical School.
Lecture 2: "Breast surgery and oncology" for 5 and 6-degree students in Medical School.
Lecture 3: "Cancer Precision Medicine" for students in Graduate School of Medical Sciences.
Lecture 4: "Up-to-date of Breast surgery and oncology" for students in Graduate School of Medical Sciences.
Lecture 5: "Chemotherapy and hormone therapy for patients with breast cancer" for cancer-expert pharmacists.
Other Educational Activities
  • 2019.06, Education for medical staff on Cancer Precision Medicine..