Kyushu University Academic Staff Educational and Research Activities Database
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Takeshi Hirota Last modified date:2019.06.19





Homepage
http://doutai.phar.kyushu-u.ac.jp/index.html
Phone
092-642-6658
Fax
092-642-6660
Academic Degree
Ph. D.
Field of Specialization
Clinical Pharmacokinetics
Outline Activities
Pharmacogenomics of drug metabolizing enzymes and transporters
Research
Research Interests
  • Nucleosome positioning and the expression mechanisms of drug transporter genes in human kidney
    keyword : nucleosome positioning, DNA methylation, drug transporter
    2013.12.
  • Novel blood-based biomarkers associated with the expressions of pharmacokinetics related genes
    keyword : biomarker, exosome, microRNA, DNA methylation, immunoprecipitation
    2010.04.
  • Identification of a transcriptional enhancer element upstream from pharmacokinetics related genes by chromosome conformation capture assay
    keyword : 3C assay, enhancer, CYP3A4
    2010.04.
  • Mechanisms of microRNA regulation in pharmacokinetics related genes
    keyword : pharmacokinetics, microRNA, DNA methylation, histone modification
    2006.04.
  • Epigenetic regulation of gene expression in pharmacokinetics
    keyword : pharmacokinetics, epigenetics, DNA methylation, histone modification
    2003.04.
  • Genetic polymorphisms of Pharmacokinetics related genes
    keyword : pharmacokinetics, polymorphisms
    2000.04.
Academic Activities
Membership in Academic Society
  • Japanese Society of Pharmaceutical Health Care and Sciences
  • The Pharmaceutical Society of Japan
  • The Japanese Society for the Study of Xenobiotics