Kyushu University [Koji Yoshimoto (Professor) Faculty of Medical Sciences, Neurological Institute]

Koji Yoshimoto

Last modified date：2023.07.05

Professor / Deaprtment of Neurosurgery, Graduate School　of Medical Sciences
Neurological Institute
Faculty of Medical Sciences

2 Academic Activities

Graduate School

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Homepage

Phone

092-642-5521

Fax

092-642-5527

Academic Degree

M.D.,Ph. D.

Country of degree conferring institution (Overseas)

Field of Specialization

Neurosurgery

Total Priod of education and research career in the foreign country

02years02months

Research

Research Interests

Development of mitochondria targeted therapy in glioblastoma
keyword : glioblastoma, mitochondria, targeted therapy, oncogene, metabolic disturbance
2023.06～2023.06.
Elucidation of metabolic mechanisms of brain tumors
keyword : Brain tumors　　Metabolic mechanisms
2021.07～2021.07.
Dissection of molecular mechanism of glioblastoma and application to the treatment based on transcriptome analysis
keyword : glioblastoma, transcriptome
2014.09～2016.09.
COX2 expression and its biological function in malignant glioma
keyword : COX2、malignant glioma
2010.04～2013.03.
Development of a new therapeutic stratergy for GBM treatment targeting the DNA repair system
keyword : GBM DNA reapir
2009.04～2012.03.
The development of new therapeutic stratergy targeted at brain tumor stem cell
keyword : Brain tumor stem cell
2008.04～2011.03.
The research about mesenchymal stem cell toward brain tumor
keyword : mesencymal stem cell
2007.04～2010.03.
The genetic and signal pathway analysis fo brain tumors
keyword : brain tumor signalling pathway
2007.04.

Academic Activities

Reports

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Papers

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1.	Hideki Murata, Koji Yoshimoto, Detection of proneural/mesenchymal marker xpression in glioblastoma: temporospatial dynamics and association with chromatin-modifying gene expression, J Neurooncol. 2015;125(1):33-41. , 2016.06.
2.	Koji Yoshimoto, Dual optical channel three-dimensional neuroendoscopy: Clinical application as an assistive technique in endoscopic endonasal surgery, 6, 45-50, 2016.06.
3.	Yoshimoto K, Ma X, Guan Y, Mizoguchi M, Nakamizo A, Amano T, Hata N, Kuga D,Sasaki T, Expression of stem cell marker and receptor kinase genes in glioblastoma tissue quantified by real-time RT-PCR, Brain Tumor Pahology, 28, 4, 291-6, 2011.10.
4.	Yoshimoto K, Dang J, Zhu S, Nathanson D, Huang T, Dumont R, Seligson D, Yong WH, Xiong Z, Rao N, Winther H, Chakravarti A, Bigner D, Mellinghoff IK, Horvath S, Cavenee WK, Cloughesy TF, Mischel PS:, Detection of EGFRvIII in routinely processed glioblastoma clinical samples, Clinical Cancer Research, 14(2): 488-493, 2008.01.

Presentations

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1.	Koji Yoshimoto, PGFRA amplification is asignificant prognostic marker in patients with IDH wild-type glioblastoma multiforme, WFNOS2022 SEOUL, 2022.03.
2.	Koji Yoshimoto, HDAC7 as a possible therapeutic target for mesenchymal glioblastoma, 21Th International Conference on Brain Tumor Research and Therapy　, 2016.04.
3.	Koji Yoshimoto, Activation of the ATM/Chk2 pathway in intracranial germinomas, 4Th International CNS Germ Cell Tumor Symposium, 2015.04.
4.	吉本幸司, Endoscopic transsphenoidal surgery -Early clinical experiences of 3D endoscopy- , Italian-Japanese Joint Meeting 2012, 2012.11.
5.	吉本幸司, Diagnostic significance of microRNA and gene expression in glioma patients., The 4th International Symposium of Brain Tumor Pathology, 2012.05.

Membership in Academic Society

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