Kyushu University Academic Staff Educational and Research Activities Database
List of Papers
Yosuke Taniguchi Last modified date:2019.06.20

Associate Professor / Bioorganic and Synthetic Chemistry / Department of Chemo-Pharmaceutical Sciences / Faculty of Pharmaceutical Sciences

1. Taniguchi Y., Miyazaki M., Matsueda N., Wang L., Okamura H. and Sasaki S, Stable and Selective Antiparallel Type Triplex DNA Formation by Targeting a GC base pair with the TFO containing One N2-Phenyl-2'-deoxyguanosine, Chem. Pharm. Bull.,, 66(6), 624-631, 2018.05.
2. Okamura H, Taniguchi Y, Sasaki S, Aminopyridinyl-pseudodeoxycytidine derivatives selectively stabilize antiparalleltriplex DNA with multiple CG inversion sites, Angew. Chem. Int. Ed., 128(40), 12633-12637, 2016.08.
3. Yin Y, Sasaki S, Taniguchi Y, Effects of 8-halo-7-deaza-2'-deoxyguanosine triphosphate on DNA synthesis by DNApolymerase and cell proliferation, Bioorg. Med. Chem., 24(16), 3856-3861, 2016.08.
4. Nishioka T, Oshiro I, Onizuka K, Taniguchi Y, Sasaki S, Efficient thymidine-selective DNA interstrand photo-activecrosslinking by the 6-thioguanine connected via an ethylene-linker to the 2'-deoxyribose unit, Chem. Pharm. Bull. , 64(9),1315-1320, 2016.07.
5. Koga Y, Taniguchi Y, Kikukawa Y, Sasaki S, Recognition and detection of 8-oxo-rG in RNA using the DNA/OMeRNAchimera probes containing fluorescent adenosine-diazaphenoxazine analogue, Bioorg. Med. Chem., 24(6), 1308-1313, 2016.05.
6. Yin Y, Sasaki S, Taniguchi Y, Inhibitory Effect of 8-Halogenated-7-deaza-2'-deoxyguanosine Triphosphates on Human 8-Oxo-2'-deoxyguanosine Triphosphatase, hMTH1, Actibities, ChemBioChem, doi/10.1002/cbic.201500589, 17(7) 566-569, 2016.05.
7. Taniguchi Y, Tomizaki A, Matsueda N, Okamura H, Sasaki S, Enhancement of TFO Triplex Formation by Conjugation withPyrene via Click Chemistry, 63 (11) 920-926., 2015.06.
8. Kikuta K, Haishun P, Brazier J, Taniguchi Y, Onizuka K, Nagatsugi F, Sasaki S, Stabilization of the i-motif structure by theintrastrand cross-link formation, 25(16), 3307-3310, 2015.06.
9. Oshiro I, Jitsuzaki D, Onizuka K, Nishimoto A, Taniguchi Y, Sasaki S, Site-specific modification of the 6-amino group ofadenosine in RNA by an inter-strand functionality-transfer reaction using an S-functionalized-4-thiothymidine, 16(8), 1199-1204, 2015.05.
10. Yin Y, Sasaki S, Taniguchi Y, Recognition and excision properties of 8-halogenated-deaza-2'-deoxyguanosine as 8-oxo-2'-deoxyguaanosine analogues and FPG and hOGG1 inhibitors, 16(8), 1190-1198 , 2015.05.
11. Taniguchi Y, Kikukawa Y, Shigeki S, Discrimination Between 8-Oxo-2'-Deoxyguanosine and 2'-Deoxyguanosine in DNA by the Single Nucleotide Primer Extension Reaction with Adap Triphosphate, 54(17), 5147-5151., 2015.04.
12. Okamura H, Taniguchi Y, Sasaki S, An Isocytidine Derivative with a 2-Amino-6-methylpyridine Unit for SelectiveRecognition of the CG Interrupting Site in an Antiparallel Triplex DNA, 15(16), 2374-2378 (2014), 2014.10.
13. Jitsuzaki D, Onizuka K, Nishimoto A, Oshiro I, Taniguchi Y, Sasaki S, Remarkable acceleration of the DNA/RNA inter-strand functionality-transfer reaction to modify a cytosine residue: the proximity effect via complexation with a metal cation, 42(13), 8808-8815 (2014), 2014.08.
14. Yamada Y, Tabata M, Yasuzaki Y, Shibata A, Ibayashi Y, Taniguchi Y, Sasaki S, Harashima H, A nanocarriersystem for the delivery of nucleic acids targeted to a pancreatic beta cell line, Biomaterials, 35(24), 6430-6438 (2014), 2014.08.
15. Yin Yizhen, Yosuke Taniguchi, Shigeki Sasaki, Synthesis of 8-halogenated-7-deaza-2'-deoxyguanosine as an8-oxo-2'-deoxyguanosine analogue and evaluation of its base pairing properties, 70(11), 2040-2047 (2014), 2014.06.
16. Yosuke Taniguchi, Keitaro Fukabori, Yoshiya Kikukawa, Yohei Koga, Shigeki Sasaki, 2,6-Diaminopurine nucleoside derivative of 9-ethyloxy-2-oxo-1,3-diazaphenoxazine(2-amino-Adap) for recognition of 8-oxo-dG in DNA, 22(5), 1634-1641 (2014), 2014.05.
17. Yosuke Taniguchi, Yohei Koga, Shigeki Sasaki, Synthesis of 8-oxoguanosine phosphoramidite and its incorporation intooligoribonucleotides, UNIT4.58 56:4.58.1-4.58., 2014.04.
18. Atsushi Nishimoto, Daichi Jitsuzaki, Kazumitsu Onizuka, Yosuke Taniguchi, Shigeki Sasaki, 4-Vinyl-Substituted Pyrimidine Nucleosides Exhibit the Efficient and SelectiveFormation of Interstrand Cross-Links with RNA and duplex DNA, DOI: 10.1093/nar/gkt197 , 41, 41(13) 6774-6781 (2013), 2013.05.
19. Hidenori Okamura, Yosuke Taniguchi, Shigeki Sasaki, N-(Guanidinoethyl)-2’-deoxy-5-methylisocytidine exhibits selective recognition of a CG interrupting site for the formation of anti-parallel triplexes, Org. Biomol. Chem., 10.1039/c3ob40472b, 11, 23, 3918-3924, 2013.05.
20. Masafumi Kumazaki, Hitoshi Ando, Masafumi Kakei, Kentarou Ushijima, Yosuke Taniguchi, Masashi Yoshida, Shiho Yamato, Satoshi Washino, Taka-aki Koshimizu, Akio Fujimura, a-Lipoic acid protects against arsenic trioxide-induced acute QT prolongation in anesthetized guinea pigs, Eur. J. Pharmacol., org/10.1016/j.ejphar.2013.02.027, 705, 1-10, 2013.04.
21. Yohei Koga, Yosuke Taniguchi, Shigeki Sasaki, Synthesis of the Oligoribonucleotides Incorporating 8-Oxo-guanosine and Evaluation of their Base Pairing Properties, Nucleosides, Nucleotides and Nucleic Acids, 10.1080/15257770.2013.767461, 32, 3, 124-136, 2013.02.
22. Yosuke Taniguchi, Hidenori Okamura, Norihiko Fujino, Shigeki Sasaki, Synthesis of 1'-phenyl-2-OMe ribose analogues connecting the thymine base at the 1' position through a flexible linker for the formation of a stable anti-parallele triplex DNA, Tetrahedron, 69, 2, 600-606, 2013.01.
23. Tamer Nasr, Yosuke Taniguchi, Tomoko Takaki, Hidenori Okamura, Shigeki Sasaki, Properties of Oligonucleotidewith Phenyl-Substituted Carbocyclic Nucleoside Analogues for the Formation ofDuplex and Triplex DNA, Nucleosides, Nucleotides and Nucleic Acids, 31, 12, 8441-8460, 2012.07.
24. Yosuke Taniguchi, Shigeki Sasaki, An efficient antigene activity and antiproliferative effect by targeting the Bcl-2 or survivin gene with triplex forming oligonucleotides containing a W-shaped nucleoside analogue (WNA-T), Org. Biomol. Chem., 10.1039/c2ob26431e, 10, 41, 8336-8341, 2012.07.
25. Yosuke Taniguchi, Ryota Kawaguchi, Shigeki Sasaki, Adenosine-1,3-diazaphenoxazine Derivative for Selective Base Pair Formation with 8-Oxo-2'-deoxyguanosine in DNA, J. Am. Chem. Soc., 133, 7272-7275., 2011.05.
26. Kazumitsu Onizuka, Atsushi Shibata, Yosuke Taniguchi, Shigeki Sasaki S, Pin-Point Chemical Modification of RNA with DiverseMolecules through the Functionality Transfer Reaction and Copper-CatalyzedAzide-Alkyne Cycloaddition Reaction, Chem. Comm, 47, 17, 5004-5006, 2011.01.
27. Shuhei Imoto, Tsuneaki Hori, Shinya Hagihara, Yosuke Taniguchi, Shigeki Sasaki, Fumi Nagatsugi, Alteration of Cross-linking Selectivity with the 2’-OMe Analogue of 2-Amino-6-Vinylpurine and Evaluation of Antisense Effects, Bioorg. Med. Chem Lett., 20, 6121-6124, 2010.08.
28. Issei Doi, Genichiro Tsuji, Kyoko Kawakami, Osamu Nakagawa, Yosuke Taniguchi and Shigeki Sasaki, The Spermine-Bisaryl Conjugate as a Potent Inducer for the B to Z-DNA Transition, Chem. Eur. J ., 16, 11993-11999, 2010.06.
29. Kazumitsu Onizuka, Yosuke Taniguchi., Shigeki Sasaki, Activation and Alteration of Base Selectivity by Metal Cations in the Functionality-Transfer Reaction for RNA Modification, Bioconjugate Chem. , 21, 1508-1512., 2010.07.
30. Zhichun Li, Osamu Nakagawa, Yohei Koga, Yosuke Taniguchi ,Shigeki Sasaki, Synthesis of New Derivatives of 8-oxoG-Clamp for Better Understanding the Recognition Mode and Improvement of Selective Affinity, Bioorg. Med. Chem, 18, 18, 3992-3998, 2010.06.
31. Yosuke Taniguchi, Yusuke Kurose, Takamasa Nishioka, Fumi Nagatsugi and Shigeki Sasaki, The alkyl-connected 2-amino-6-vinylpurine (AVP) crosslinking agent for improved selectivity to the cytosine base in RNA, Bioorg Med. Chem., 18, 2894-2901, 18,2894-2901, 2010.02.
32. Kazumitsu Onizuka, Yosuke Taniguchi and Shigeki Sasaki, A New Usage of Functionalized Oligodeoxynucleotide Probe for Site-Specific Modification of a Guanine Base within RNA, Nucleic Acids Res, 18, 2894-2901, 18, 2894-2901, 2010.01.
33. Yosuke Taniguchi, Yusuke Kurose, Takamasa Nishioka, Fumi Nagatsugi and Shigeki Sasaki, Evaluation of the antisense effect of PEGylated oligodeoxynucleotides containing intelligent nucleoside analogues, Nucleic Acids Symp. Ser., 53, 167-168., 2009.10.
34. Kazumitsu Onizuka, Yosuke Taniguchi, Takamasa Nishioka and Shigeki Sasaki, Site-specific modification of RNA by functionality-transfer ODN probes, Nucleic Acids Symp. Ser., 2009.10.
35. Kazumitsu Onizuka, Yosuke Taniguchi and Shigeki Sasaki, A New Odorless Procedure for the synthesis of 2'deoxy-6-thioguanosine and It Incorporation Into Oligonucleotides, Nucleoside Nucleotide and Nuclec acid., 28, 752-760., 2009.10.
36. Yosuke Taniguchi, Yuko Uchida, Tomoko Takaki, Eriko Aoki and Shigeki Sasaki, Recognition of the CG interrupting site by W-shaped nucleoside analogs (WNA) having the pyrozole ring in an anti-parallel triplex DNA, Bioorg Med. Chem., 17, 6803-6810., 2009.09.
37. Kazumitsu Onizuka, Yosuke Taniguchi and Shigeki Sasaki, Site-Specific Covalent Modification of Nucleic Acids Guided by Functionality-Transfer Oligodeoxynucleotides, Bioconjugate Chem., 20, 799-803., 2009.04.
38. Tamer Nasr, Zhichun Li, Osamu Nakagawa, Yosuke Taniguchi, Sayaka Ono and Shigeki Sasaki, Selective fluorescence quenching of the 8-oxoG-clamp by 8-oxodeoxyguanosine in ODN, Bioorg. Med. Chem. Lett., 19, 727-730, 2009.01.
39. Yuko Uchida, Yosuke Taniguchi, Eriko Aoki, Mieko Togo and Shigeki Sasaki, Formation of a stable triplex incorporating a CG interrupting site by a new WNA derivative containing 3-aminopyrazole as a nucleobase, Nucleic Acids Symp. Ser., 52, 137-138. , 2008.09.
40. Kazumitsu Onizuka, Yosuke Taniguchi, Takamasa Nishioka and Shigeki Sasaki, Site-specific modification by functionality-transfer oligonucleotide with the photo-inducible reactivity, Nucleic Acids Symp. Ser., 52, 367-368., 2008.09.
41. Yusuke Kurose, Yosuke Taniguchi, Fumi Nagatsugi and Shigeki Sasaki, Synthesis of the new nucleoside analogue connecting 2-amino-6-vinylpurine to the 2’-deoxyribose skeleton via the methylene linker, Nucleic Acids Symp. Ser., 52, 43-44., 2008.09.
42. Kazumitsu Onizuka, Yosuke Taniguchi and Shigeki Sasaki, Design of S-vinylated 6-thioguanosine as a specific modifier of cytidine, Collection Symp. Ser, 10, 159-163., 2008.06.
43. Yosuke Taniguchi, Mieko Togo, Eriko Aoki, Yuko Uchida and Shigeki Sasaki, Synthesis of p-amino-WNA derivatives to enhance the stability of the anti-parallel triplex, Tetrahedron, 64,7164-7170, 2008.05.
44. Tamer Nasr, Yosuke Taniguchi and Shigeki Sasaki, SYNTHESIS OF 1’-PHENYL SUBSTITUTED NUCLEOSIDE ANALOGS, Heterocycles, 2659-2668, 2007.12.
45. Yosuke Taniguchi and Eric T. Kool, Syntheses and properties of low-polarity shape mimics of 8-oxopurines, Nucleic Acids Symp. Ser., 51, 217-218., 2007.11.
46. Eriko Aoki, Yosuke Taniguchi and Shigeki Sasaki, Effective strand invasion by ODN incorporating a new bicyclic nucleoside analogue (WNA), Nucleic Acids Symp. Ser., 51, 255-256., 2007.11.
47. Kazumitsu Onizuka, Yosuke Taniguchi and Shigeki Sasaki, Development of novel thioguanosine analogs with the ability to specifically modify cytidine, Nucleic Acids Symp. Ser., 51, 5-6., 2007.11.
48. Yosuke Taniguchi and Eric T. Kool, Nonpolar Isosteres of Damaged DNA Bases: Effective Mimicry of Mutagenic Properties of 8-Oxopurines, J. Am. Chem. Soc. , 129, 8836-8844, 2007.07.
49. Yosuke Taniguchi, Ayako Nakamura, Yusuke Senko, Fumi Nagatsugi and Shigeki Sasaki, Effects of Halogenated WNA Derivatives on Sequence Dependency for Expansion of Recognition Sequences in Non-Natural-Type Triplexes, J. Org. Chem., 71, 2115–2122. , 2006.04.
50. Eriko Aoki, Yosuke Taniguchi, Mieko Togo and Shigeki Sasaki, Effect of the modified aromatic ring of WNA on stability of triplex DNA, Nucleic Acids Symp. Ser., 50, 185–186., 2006.11.
51. Yosuke Taniguchi, Ayako Nakamura, Yusuke Senko, Keiichi Kodama, Fumi Nagatsugi and Shigeki Sasaki, Expansion of triplex recognition codes by the use of novel bicyclic nucleoside derivatives (WNA), Nucleosides Nucleotides and Nucleic Acids., 10.1081/NCN-200060309, 24, 5-7, 823-827, 24, 823–827. , 2005.12.
52. Yosuke Taniguchi, Ayako Nakamura, Eriko Aoki and Shigeki Sasaki, Modification of the aromatic ring of the WNA analogues for expansion of the triplex recognition codes, Nucleic Acids Symp. Ser., 49, 173–174., 2005.11.
53. Shigeki Sasaki, Yosuke Taniguchi, Ryo Takahashi, Yusuke Senko, Keiichi Kodama, Fumi Nagatsugi and Minoru Maeda, Selective Formation of Stable Triplexes Including a TA or a CG Interrupting Site with New Bicyclic Nucleoside Analogues (WNA), J. Am. Chem. Soc., 10.1021/ja037211z, 126, 2, 516-528, 126, 516–528., 2004.01.
54. Yosuke Taniguchi, Yusuke Senko, Keiichi Kodama, Ayako Nakamura and Shigeki Sasaki, Design and evaluation of novel nucleoside analogs (WNA) for specific formation of non-natural type triplexes containing a TA or CG interrupting site, Nucleic Acids Res. Suppl, 3, 113–114., 2003.11.
55. Yosuke Taniguchi, Ryo Takahashi, Keiichi Kodama, Yusuke Senko, Minoru Maeda and Shigeki Sasaki, Selective formation of non-natural type triplexes containing TA interrupting sites with the TFO incorporating W-shape nucleic acid (WNA) analogs, Nucleic Acids Res. Suppl., 2, 35–36., 2002.11.
56. Shigeki Sasaki, Hiroyuki Yamauchi, Fumi Nagatsugi, Ryo Takahashi, Yosuke Taniguchi and Minoru Maeda, W-shape nucleic acid (WNA) for selective formation of non-natural anti-parallel triplex including a TA interrupting site, Tetrahedron Lett., 10.1016/S0040-4039(01)01446-0, 42, 39, 6915-6918, 42, 6915–6918., 2001.01.
57. Shigeki Sasaki, Hiroyuki Yamauchi, Ryo Takahashi, Yosuke Taniguchi and Minoru Maeda, New base analogs for the formation of non-natural triplexes, Nucleic Acids Res. Suppl., 1, 23–24., 2001.11.