Kyushu University Academic Staff Educational and Research Activities Database
Researcher information
Kawabe Yoshinori Last modified date:2013.5.21

Assistant Professor / Molecular and Biochemical Systems Engineering
Department of Chemical Engineering
Faculty of Engineering


Graduate School
Undergraduate School


E-Mail
Homepage
[URL].
Phone
092-802-2783
Fax
092-802-2793
Academic Degree
Doctor of Engineering
Field of Specialization
Biochemical Engineering
Research
Research Interests
  • Mass production sysytem for the biopharmaceutical proteins by transgenic avian bioreactor
    keyword : transgenic avian bioreactor, biopharmaceuticals, recombinant proteins, monoclonal antibody, retroviral vector
    2004.04.
  • development of maintainance and efficient derivation for pluripotential stem cells
    keyword : pluripotential stem cells, genetically manipulated animals, feeder layer, tissue engineering
    2008.04.
Academic Activities
Books
1. Kawabe Y, Kamihira M,Antibody Expression and Production - Chapter 6 Production of Antibody by Transgenic Avians Cell Engineering Volume 7 SpringerLink,pp121-141,2011.04.
Papers
1. Kawabe Y, Hayashida Y, Numata K, Harada S, Hayashida Y, Ito A, Kamihira M ,Oral immunotherapy for pollen allergy using T-cell epitope-containing egg white derived from genetically manipulated chickens,PLOS ONE,Vol.7,pp.e48512,2012.10.
2. Kawabe Yoshinori, Makitsubo H, Kameyama Y, Huang S, Akira Ito, Masamichi Kamihira,Repeated integration of antibody genes into a pre-selected chromosomal locus of CHO cells using an accumulative site-specific gene integration system.,Cytotechnology,64(3)、267-279,2012.05.
3. Obayashi H, Kawabe Y, Makitsubo H, Watanabe R, Kameyama Y, Huang S, Takenouchi Y, Ito A, Kamihira M,Accumulative gene integration into a pre-determined site using Cre/loxP.,J Biosci Bioeng,Vol.113,No.3,pp.381-388,2012.05.
4. Huang S, Kawabe Y, Ito A, Kamihira M,Adeno-associated virus Rep-mediated targeting of integrase-defective retroviral vector DNA circles into human chromosome 19.,Biochem Biophys Res Commun,Vol.417,No.1,pp.78-83,2012.01.
5. Yamamoto H, Kawabe Y, Ito A, Kamihira M,Enhanced liver functions in mouse hepatoma cells by induced overexpression of liver-enriched transcription factors.,Biochem Eng J,Vol.60,No.15,pp.67-73,2012.01.
6. Huang S, Kawabe Y, Ito A, Kamihira M ,Cre recombinase-mediated site-specific modification of a celluar genome using an integrase-defective retroviral vector,Biotechnol Bioeng,107: 717-29,2010.11.
7. Kameyama Y, Kawabe Y, Ito A, Kamihira M.,An accumulative site-specific gene integration system using Cre recombinase-mediated cassette exchange.,Biotechnol Bioeng. ,105(6):1106-14.,2010.04.
8. Penno CA, Kawabe Y, Ito A, Kamihira M.,Production of recombinant human erythropoietin/Fc fusion protein by genetically manipulated chickens,Transgenic Res. ,19(2):187-95.,2010.04.
9. Kamihira M, Kawabe Y, Shindo T, Ono K, Esaka K, Yamashita T, Nishijima K, Iijima S,Production of chimeric monoclonal antibodies by genetically manipulated chickens,J Biotechnol. ,141(1-2):18-25.,2009.04.
10. Kawabe Y, Naka T, Komatsu H, Nishijima K, Iijima S, Kamihira M.,Retroviral gene transduction into chicken embryo gonads through blood circulation,J Biosci Bioeng,106(6):598-601,2008.12.
11. Kameyama Y, Kawabe Y, Ito A, Kamihira M,Antibody-dependent gene transduction using gammaretroviral and lentiviral vectors pseudotyped with chimeric vesicular stomatitis virus glycoprotein,J Virol Methods,Vol.153,No.1,pp.49-54,2008.06.
12. Kawabe Y, Naka T, Ando-Noumi N, Matsumoto H, Ono K, Nishijima K, Kamihira M, Iijima S,Transport of human Immunoglobulin G and Fc-Fusion Proteins to Chicken Egg Yolk,J Biosci Bioen,Vol.102,No.6,pp.518-523,2006.12.
13. Kawabe Y, Kamihira M, Ono K, Kyogoku K, Nishijima K, Iijima S,Production of scFv-Fc Fusion Protein by Genetically Manipulated Quails,J Biosci Bioeng ,Vol.102,No.4,pp.297-303,2006.10.
14. Yoshinori Kawabe, Akitsu Hotta, Ken-ichiro Ono, Kazuhisa Esaka, Ken-ichi Nishijima, Masamichi Kamihira, and Shinji Iijima,Production of chimeric antibodies by transgenic chicken bioreactor,Animal Cell Technology: Basic & Applied Aspects,14,307-314,2006.05.
Membership in Academic Society
  • The Society of Biotechnology, Japan
  • The Society of Chemical Engineers, Japan
  • Japanese Association for Animal Cell Technology
  • The Molecular Biology Society of Japan