Kyushu University Academic Staff Educational and Research Activities Database
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Nakaya Michio Last modified date:2017.10.04

Associate Professor / Department of Pharmacology and Toxicology
Department of Pharmaceutical Health Care and Sciences
Faculty of Pharmaceutical Sciences


Graduate School
Undergraduate School


Homepage
http://chudoku.phar.kyushu-u.ac.jp/
Academic Degree
Ph.D in Medicine
Field of Specialization
Molecular Biology, Pharmacology
Research
Research Interests
  • Analysis of signal transduction mechanisms that are involved in the cardiac diseases.
    keyword : heart, signal transduction
    2008.01.
  • G-protein independent signaling induced by a beta-blocker and the significance of the signaling
    keyword : beta-blocker
    2007.07.
  • Identification of G-protein coupled receptor kinase 6
    keyword : GRK6
    2010.02.
Academic Activities
Reports
1. Michio Nakaya, Mina Ohba, Motohiro Nishida and Hitoshi Kurose, Determining the Activation of Rho as an Index of Receptor Coupling to G12/13 Proteins, Methods in Molecular Biology, 2011.04.
2. Hanayama R, Miyasaka K, Nakaya M, Nagata S., MFG-E8-dependent clearance of apoptotic cells, and autoimmunity caused by its failure., Curr Dir Autoimmun, 2006.06.
Papers
1. 仲矢 道雄, 渡健治, 田島充, TAKEO NAKAYA, 松田翔一, 西原弘朗, 山口裕嗣, 橋本明子, 西田光甫, AKIOMI NAGASAKA, 堀井雄馬, 小野達貴, Gentaro Iribe, Ryuji Inoue, TSUDA MAKOTO, Kazuhide Inoue, Akira Tanaka, Masahiko Kuroda, Shigekazu Nagata, Cardiac myofibroblast engulfment of dead cells facilitates recovery after myocardial infarction, JOURNAL OF CLINICAL INVESTIGATION, 127, 1, 383-401, 2017.01.
2. Nakaya Michio, 渡健治, Motohiro Nishida, Kyeong-Man Kim, Hitoshi Kurose, β-arrestin2 in infiltrated macrophages inhibits excessive inflammation after myocardial infarction, PLoS One, 8(7), 2013.05.
3. Nakaya Michio, Mitsuru Tajima, Hidetaka Kosako, Takeo Nakaya, Hiroaki Nishihara, Mina Ohba, Shiori Komiya, Naoki Tani, Motohiro Nishida, Hisaaki Taniguchi, Yoji Sato, Mitsuru Matsumoto, TSUDA MAKOTO, Masahiko Kuroda, Kazuhide Inoue, Hitoshi Kurose, GRK6 deficiency in mice causes autoimmune disease due to impaired apoptotic cell clearance., Nat. Commun. , 287, 1532, 2013.02.
4. Nakaya Michio, Chikura Satsuki, Watari Kenji, Mizuno Natsumi, Mochinaga Koji, Supachoke Mangmool, Koyanagi Satoru, shigehiro ohdo, Sato Yoji, Ide Tomomi, Motohiro Nishida, Hitoshi Kurose, Induction of cardiac fibrosis by β-blocker in G protein-independent but GRK5/β-arrestin2-dependent signaling pathways. , J. Biol. Chem. , 287, 35669-35677, 2012.08.
5. Nishida M, Sato Y, Uemura A, Narita Y, Toazaki-Saitoh H, Nakaya M, Ide T, Suzuki K, Inoue K, Nagao T, Kurose H., P2Y6 receptor-Galpha12/13 signalling in cardiomyocytes triggers pressure overload-induced cardiac fibrosis., EMBO Journal, 27(23) 3104-3115., 2008.12.
6. Michio Nakaya, Masahiro Kitano, Michiyuki Matsuda, Shigekazu Nagata, Spatiotemporal regulation of Rac1 to control actin patch for engulfment of apoptotic cells, Proceedings of the National Academy of Sciences, 105 (27) 9198-9203, 2008.07.
7. Masahiro Kitano, Michio Nakaya, Takeshi Nakamura, Shigekazu Nagata, Michiyuki Matsuda, Imaging of Rab5 activity identifies essential regulators for phagosome maturation, Nature, 453 (7192) 241-245, 2008.05.
8. Nakaya M, Tanaka M, Okabe Y, Hanayama R, Nagata S, Opposite effects of Rho family GTPases on engulfment of apoptotic cells by macrophages., Journal of Biological Chemistry, 281(13) 8836-8842, 2006.03.
Presentations
1. 仲矢 道雄, Engulfment of dead cells in the event of a myocardial infarction, Japan Australia Meeting on Cell Death, 2015.10.22.