| Kaoru Takegawa | Last modified date：2013.5.18 |
Graduate School
Undergraduate School
E-Mail
Homepage
[URL].
Phone
092-642-2849
Fax
092-642-2849
Academic Degree
Ph.D
Field of Specialization
Applied Microbiology
Outline Activities
Vesicle-mediated protein trafficking in yeasts. Heterologous protein production in yeast. Structure and physiological role for fungal glycoproteins.
Research
Research Interests
- Production of heterologous proteins using the fission-yeast (Schizosaccharomyces pombe) expression system.
keyword : Fission yeast, heterologous proteins, gene expression
1997.04. - Vesicle-mediated protein transport pathways to the vacuole in yeast
keyword : Yeast, vacuole, vesicle trafficking, protein degradation
1991.10. - Transglycosylation activity and its application of endo-β-N-acetylglucosaminidase
keyword : Endoglycosidase, transglycosylation activity, neoglycoconjugates
1991.04. - Structures and physiological roles of protein glycosylation in microbial eukaryotes.
keyword : Glycoprotein, sugar chains
1984.04.
Reports
| 1. | Takegawa Kaoru,Guidelines for the use and interpretation of assays for monitoring autophagy.,8, 445-544 (2012).,Autophagy,2012.04. |
| 2. | Takegawa Kaoru,Galactose-specific recognition system in the fission yeast Schizosaccharomyces pombe.,135, 24-42 (2012).,Trends Glycosci. Glycotechnol.,2012.03. |
| 3. | Takegawa Kaoru,Engineering of protein secretion in yeast: strategies and impact on protein production.,86, 403-417,Appl. Microbiol. Biotechnol. ,2010.03. |
| 4. | Takegawa Kaoru,Autophagy in the fission yeast Schizosaccharomyces pombe.,584, 1327-1334 ,FEBS Lett. ,2010.03. |
| 5. | Takegawa Kaoru,Production of heterologous proteins using the fission-yeast (Schizosaccharomyces pombe) expression system.,53, 227-235 ,Biotechnol Appl Biochem.,2009.12. |
Papers
| 1. | Sasaki M, Kumagai H, Takegawa K, Tohda H,Characterization of genome-reduced fission yeast strains.,Nucleic Acid Research,in press (2013).,2013.05. |
| 2. | Takegawa Kaoru, Ohashi Takao, Fujiyama Kazuhito,Identification of novel α1,3-galactosyltransferase and elimination of α-galactose-containing glycans by disruption of multiple α-galactosyltransferase genes in Schizosaccharomyces pombe,Journal of Biological Chemistry,287(46), 38866-38875 (2012),2012.11. |
| 3. | Takegawa Kaoru,Identification of galactose-specific flocculin essential for nonsexual flocculation and hyphal growth in Schizosaccharomyces pombe,Molecular Microbiology,82(6) 1531-1544 (2011),2011.12. |
| 4. | Takegawa Kaoru,Loss-of- and gain-of-function mutations in FAB1A/B impair endomembrane homeostasis, conferring pleiotropic developmental abnormalities in Arabidopsis.,Plant Physiology,155(2), 797-807 (2011),2011.02. |
| 5. | Takegawa Kaoru,Mannosylinositol phosphorylceramide is a main phospholipid component and required for proper localization of plasma membrane proteins in Schizosaccharomyces pombe.,Journal of Cell Science,123(9), 1578-1587 (2010),2010.05. |
| 6. | Takegawa Kaoru,Critical roles of Mucin 1 glycosylation by transactivated polypeptide N-acetylgalactosaminyltransferase 6 in mammary carcinogenesis.,Cancer Research,70(7), 2759-2769 (2010),2010.04. |
| 7. | Takegawa Kaoru,Role of septins in the orientation of forespore-membrane extension during sporulation in fission yeast.,Molecular and Cellular Biology,30(8), 2057-2074 (2010),2010.04. |
| 8. | Takegawa Kaoru,Two Schizosaccharomyces pombe Rab7 homologs, Ypt7 and Ypt71, play antagonistic roles in the regulation of vacuolar morphology.,Traffic,10(7), 912-924 (2009),2009.07. |
| 9. | Takegawa Kaoru,A simple and effective chromosome modification method for large-scale deletion of genome sequences and identification of essential genes in fission yeast. ,Nucleic Acids Res. ,34, e11 ,2006.02. |
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