Kyushu University Academic Staff Educational and Research Activities Database
Researcher information
Shinji Okano Last modified date:2011.5.26



Graduate School
Undergraduate School


Homepage
http://www.med.kyushu-u.ac.jp/pathol1/
Homepage of Division of Pathophysiological and Experimental Pathology, Department of Pathology, Graduate School of Medical Sciences, Kyushu University
.
Phone
092-642-6064
Fax
092-942-5965
Academic Degree
M.D. Ph.D.
Field of Specialization
Immunology, Pathology, Oncology
Outline Activities
,
Research
Research Interests
  • Basical reserch for chronic hepatitis due to HCV.
    keyword : HCV
    2003.10~2009.10.
  • Basical reserch for transplantation immunology
    keyword : transplatation immunology
    2001.04~2009.10.
  • Basical reserch for cancer immunotherapy
    keyword : tumor immunology
    2003.10~2009.10.
Academic Activities
Papers
1. Okano S, Yonemitsu Y, Maehara Y, Harada M, Yoshikai Y, Inoue M, Hasegawa M, Sueishi K.
,Provision of continuous maturation signaling to dendritic cells by RIG-1-stimulating cytosolic RNA synthesis of Sendai virus.
,J Immunol.,Vol.186,No.3,pp.1828-39,2011.02.
2. Kondoh H, Okano S, Yoshida K, Yonemitsu Y, Tomita Y, Yoshikai Y, Wake N, Sueishi K.,Semi-allogeneic dendritic cells injected via the intratumoural injection route show efficient antitumour effects in cooperation with host-derived professional antigen-presenting cells.,Scand J Immunol.,Vol.72,No.6,pp.476,2010.12.
3. Kayashima H, Toshima T, Okano S, Taketomi A, Harada N, Yamashita Y, Tomita Y, Shirabe K, Maehara Y.,Intratumoral neoadjuvant immunotherapy using IL-12 and dendritic cells is an effective strategy to control recurrence of murine hepatocellular carcinoma in immunosuppressed mice.,J Immunol.,Vol.185,No.1,pp.698,2010.07.
4. Shibata, S., Okano, S., Yonemitsu, Y., Onimaru, M., Sata, S., Nagata-Takeshita, H., Inoue, M., Zhu, T., Hasegawa, M., Moroi, Y., Furue, M., and Sueishi, K.,Induction of efficient antitumor immunity using dendritic cells activated by recombinant Sendai virus and its modulation by exogenous IFN-beta gene.,J Immunol, 177, 3564-3576,2006.09.
5. Nagata, S., Okano, S., Yonemitsu, Y., Nakagawa, K., Tomita, Y., Yoshikai, Y., Shimada, M., Maehara, Y., and Sueishi, K.,Critical roles of memory T cells and antidonor immunoglobulin in rejection of allogeneic bone marrow cells in sensitized recipient mice.,Transplantation, 82, 689-698,2006.09.
6. Harada, N., Shimada, M., Okano, S., Suehiro, T., Soejima, Y., Tomita, Y., and Maehara, Y.,IL-12 gene therapy is an effective therapeutic strategy for hepatocellular carcinoma in immunosuppressed mice.,J Immunol,173, 6635-6644,2004.11.
7. Minagawa, R., Okano, S., Tomita, Y., Kishihara, K., Yamada, H., Nomoto, K., Shimada, M., Maehara, Y., Sugimachi, K., and Yoshikai, Y.,The critical role of Fas-Fas ligand interaction in donor-specific transfusion-induced tolerance to H-Y antigen.,Transplantation,78, 799-806,2004.09.
8. Okano, S., Yonemitsu, Y., Nagata, S., Sata, S., Onimaru, M., Nakagawa, K., Tomita, Y., Kishihara, K., Hashimoto, S., Nakashima, Y., Sugimachi, K., Hasegawa, M., and Sueishi, K.,Recombinant Sendai virus vectors for activated T lymphocytes.,Gene Ther,10, 1381-1391,2003.07.
9. Okano, S., Eto, M., Tomita, Y., Yoshizumi, T., Yamada, H., Minagawa, R., Nomoto, K., and Sugimachi, K.,Cyclophosphamide-induced tolerance in rat orthotopic liver transplantation.,Transplantation,71, 447-456.,2001.03.
Membership in Academic Society
  • The American Association of Immunologist
  • The Japanese Society of Gastroenterological Surgery
  • Japanese Society of Gastroenterology
  • Japanese Society for Transplantation
  • The Japan Society of Hepatology
  • The Japanese Society of Pathology
  • Japanese Society for immunology
  • Japan Surgical Society