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Researcher information
Shinsuke Sando Last modified date：2013.1.23

Professor / Science and technology for soft materials
Inamori Frontier Research Center


Graduate School
Department of Chemistry and Biochemistry
Graduate School of Engineering


Academic Degree
Engineering
Field of Specialization
Chemical Biology
Research
Research Interests
  • Nucleic Acid Medicine
    keyword : Immunotherapy, DDS
    2009.03.
  • Chemical Biology（Vivo）
    keyword : Molecular Imaging(MRI), Metabolism, Early Diagnostics
    2009.03.
  • Chemical Biology（細胞）
    keyword : 細胞、Chemical Probe
    2001.04.
  • Nucleic Acid Chemistry
    keyword : Nucleic Acid
    2009.02～2001.04.
Academic Activities
Papers
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1. Tomohiro Doura, Ryunosuke Hata, Hiroshi Nonaka, Kazuhiro Ichikawa, Shinsuke Sando*,Design of a 13C Magnetic Resonance Probe Using a Deuterated Methoxy Group as a Long-Lived Hyperpolarization Unit,Angew. Chem. Int. Ed., 2012, 51, 10114-10117..
2. Takeshi Tokunaga, Shigeyuki Namiki, Katsuhiro Yamada, Takahiro Imaishi, Hiroshi Nonaka, Kenzo Hirose, Shinsuke Sando*,Cell Surface-Anchored Fluorescent Aptamer Sensor Enables Imaging of Chemical Transmitter Dynamics,J. Am. Chem. Soc., 2012, 134, 9561-9564..
3. Koya Yamaguchi, Ryosuke Ueki, Hiroshi Nonaka, Fuminori Sugihara, Tetsuya Matsuda, Shinsuke Sando*,Design of Chemical Shift-Switching 19F Magnetic Resonance Imaging Probe for Specific Detection of Human Monoamine Oxidase A,J. Am. Chem. Soc.,Vol.133,pp.14208-14211,2011.08.
4. Koya Yamaguchi, Ryosuke Ueki, Hisatsugu Yamada, Yasuhiro Aoyama, Hiroshi Nonaka, Shinsuke Sando*,In situ analysis of [8-13C-7-15N]-double-labelled theophylline by triple resonance NMR technique,Anal. Methods.,2011, 3, 1664-1666,2011.05.
5. Tomohiro Doura, Hiroshi Nonaka, Shinsuke Sando*,Atom Arrangement Strategy for Designing Turn-On 1H Magnetic Resonance Probe: Dual Activatable Probe for Multimodal Detection of Hypochlorite,Chem. Commun.,2012, 48, 1565-1567.,2011.05.
6. Shinsuke Sando*,Design of Functional Nucleic Acid Systems for Biomolecular Analysis,Bull. Chem. Soc. Jpn. ,2011, 84, 133-140 ,2011.02.
7. Keigo Mizusawa, Ryuji Igarashi, Kosei Uehira, Yoshimasa Takafuji, Yasuhiko Tabata, Hidehito Tochio, Masahiro Shirakawa,* Shinsuke Sando,* Yasuhiro Aoyama*,Turn-On Detection of Targeted Biochemical Reactions by Triple Resonance NMR Analysis Using Isotope-labeled Probe,Chem. Lett.,2010, 39, 926–928.,2010.07.
8. Chika Furutani, Kazuki Shinomiya, Yasuhiro Aoyama,* Katsuhiro Yamada, and Shinsuke Sando*,Modular Blue Fluorescent RNA Sensors for Label-Free Detection of Target Molecules,Mol. Biosystems ,2010, 6, 1569-1571.
,2010.03.
9. Hiroki Masu, Atsushi Narita, Takeshi Tokunaga, Masayoshi Ohashi, Yasuhiro Aoyama,* and Shinsuke Sando*
,An activatable siRNA probe: trigger-RNA-dependent activation of RNAi function,Angew. Chem. Int. Ed.,2009, 48, 9481-9483.
,2009.11.
10. Keigo Mizusawa, Kenji Abe, Shinsuke Sando, and Yasuhiro Aoyama,Synthesis of Puromycin Derivatives with Backbone-Elongated Substrates and Associated Translation Inhibitory Activities,Bioorg. Med. Chem. ,2009, 17, 2381-7,2009.03.
11. Atsushi Narita, Kazumasa Ogawa, Shinsuke Sando,* Yasuhiro Aoyama*
,Visible Sensing of Nucleic Acid Sequences Using a Genetically-Encodable Unmodified RNA as a Prob,Angewandte Chem. Int. Ed. ,2006, 45, 2879-2883.,2006.03.
12. Kazuki Matsui, Shinsuke Sando, Takashi Sera, Yasuhiro Aoyama,* Yoshihiro Sasaki, Takayoshi Komatsu, Takashi Terashima, and Jun-ichi Kikuchi*,Cerasome as an Infusible, Cell-Friendly, and Serum-Compatible Transfection Agent in a Viral Size,J. Am. Chem. Soc.,2006, 128, 3114-3115.
,2006.02.
13. Atsushi Ogawa, Shinsuke Sando,* Yasuhiro Aoyama*,Termination-free prokaryotic protein translation by using anticodon-adjusted E. coli tRNASer as unified suppressors of the UAA/UGA/UAG stop codons: Read-through ribosome display of full-length DHFR with translated UTR as a buried spacer arm,ChemBioChem,2006, 7, 249-252,2005.12.
14. Kazuki Matsui, Shohei Horiuchi, Shinsuke Sando, Takashi Sera, Yasuhiro Aoyama*
,RNAi silencing of exogenous and endogenous reporter genes using a macrocyclic octaamine as a "compact" siRNA carrier: Studies on the nonsilenced residual activity,Bioconjugate Chem.,2006, 17, 132-138,2005.12.
15. Shinsuke Sando,* Keiichiro Kanatani, Nobihiko Sato, Hironori Matsumoto, Takahiro Hohsaka, Yasuhiro Aoyama*,A Small-Molecule-Based Approach for Sense Codon Templated Synthesis of Unnatural-Natural Hybrid Proteins/Oligopeptides,J. Am. Chem. Soc.,127, 7998-7999.,2005.05.
16. Shinsuke Sando,* Atsushi Narita, Kenji Abe, Yasuhiro Aoyama*
,Doubly Catalytic Sensing of HIV-1 Related CCR5 Sequence in Prokaryotic Cell-Free Translation System Using Riboregulator-Controlled Luciferase Activity,J. Am. Chem. Soc. ,127, 5300-5301.,2005.03.
17. Shinsuke Sando,* Atsushi Narita, Toshinori Sasaki, Yasuhiro Aoyama*
,Locked TASC probes for homogeneous sensing of nucleic acids and imaging of fixed E. coli cells,Org. Biomol. Chem.,2005, 3, 1002-1007.,2005.02.
18. Atsushi Ogawa, Naotoshi Tomita, Naoko Kikuchi, Sshinsuke Sando,* Yasuhiro Aoyama*
,Aptamer Selection for the Inhibition of Cell Adhesion with Fibronectin as Target,Bioorg. Med. Chem. Lett. ,2004, 14, 4001-4004,2004.06.
19. Fumio Osaki, Takashi Kanamori, Shinsuke Sando, Takashi Sera, Yasuhiro Aoyama*
,A Quantum Dot Conjugated Sugar Ball and Its Cellular Uptake: On the Size Effects of Endocytosis in the Subviral Region,J. Am. Chem. Soc. , 2004, 126, 6520-6521.
,2004.05.
20. Shinsuke Sando,* Atsushi Narita, Yasuhiro Aoyama*
,A Facile Route to Dynamic Glycopeptide Libraries Based on Disulfide-Linked Sugar-Peptide Coupling,Bioorg. Med. Chem. Lett. ,2004, 14, 2835-2838.,2004.04.
21. Naotoshi Tomita, Shinsuke Sando, Takashi Sera, Yasuhiro Aoyama*,Macrocyclic proteoglycan mimics Potent inhibition of cell adhesion by a bundle of chondroitin sulfate chains assembled on the calix[4]resorcarene platform,Bioorg. Med. Chem. Lett.,2004, 14, 2087-2090.,2004.03.
22. Shinsuke Sando, Hiroshi Abe, and Eric T. Kool*
,Quenched Auto-Ligating DNAs Multicolor Identification of Nucleic Acids at Single Nucleotide Resolution,J. Am. Chem. Soc. ,2004, 126, 1081-1087,2004.01.
23. Shinsuke Sando,* Toshinori Sasaki, Keiichiro Kanatani, Yasuhiro Aoyama*,Amplified Nucleic Acid Sensing Using Programmed DNAzyme,J. Am. Chem. Soc.,2003, 125, 15720-15721.,2003.12.
24. Shinsuke Sando,* Kazuki Matsui, Yusuke Niinomi, Nobuhiko Sato, and Yasuhiro Aoyama*,Facile Preparation of DNA-tagged Carbohydrates,Bioorg. Med. Chem. Lett.,2003, 13, 2633-2636.,2003.08.
25. Takashi Nakai, Takashi Kanamori, Shinsuke Sando, and Yasuhiro Aoyama*
,Remarkably Size-Regulated Cell Invasion by Artificial Viruses Saccharide-Dependent Self-Aggregation of Glycoviruses and Its Consequences in Glycoviral Gene Delivery,J. Am. Chem. Soc. ,2003, 125, 8465-8475.
,2003.06.
26. Yasuhiro Aoyama,* Takashi Kanamori, Takashi Nakai, Toshinori Sasaki, Shohei Horiuchi, Shinsuke Sando, and Takuro Niidome,Size-Controlled Gene Coating with Glycocluster Nanoparticles,J. Am. Chem. Soc. ,2003, 125, 3455-3457,2003.03.
27. Osamu Hayashida, K. Mizuki, K. Akagi, A. Matsuo, Takashi Kanamori, Takashi Nakai, Shinsuke Sando, and Yasuhiro Aoyama*
,Macrocyclic Glycoclusters Self-Aggregation and Phosphate-Induced Agglutination Behaviors of Calix[4] resorcarene-Based Quadruple-Chain Amphiphiles with a Huge Oligosaccharide Pool,J. Am. Chem. Soc. ,2003, 125, 594-601.
,2002.12.
28. Shinsuke Sando and Eric. T. Kool*,Imaging of RNA in Bacteria with Self-Ligating Quenched Probes,J. Am. Chem. Soc.,2002, 124, 9686-9687.,2002.07.
29. Shinsuke Sando and Eric. T. Kool*
,Quencher as Leaving Group Efficient Detection of DNA-joining Reactions,J. Am. Chem. Soc. ,2002, 124, 2096-2097.,2002.02.
30. Kazuhiko Nakatani,* Shinsuke Sando, Hiroyuki Kumasawa, Jun Kikuchi, Isao Saito*
,Recognition of guanine-guanine mismatches by the dimeric form of 2-amino-1,8-naphthyridine,J. Am. Chem. Soc.,2001, 123, 12650-12657.

,2001.11.
31. Kazuhiko Nakatani,* Shinsuke Sando, Isao Saito*
,Improved selectivity for the binding of naphthyridine dimer to guanine-guanine mismatch,Bioorg. Med. Chem. ,2001, 9, 2381-2385,2001.09.
32. Kazuhiko Nakatani,* Shinsuke Sando, Kohzo Yoshida, Isao Saito*,Specific binding of 2-amino-1,8-naphthyridine into a single guanine bulge as evidenced by photooxidation of GG doublet,Bioorg. Med. Chem. Lett. ,2001, 11, 335-337,2001.02.
33. Kazuhiko Nakatani,* Shinsuke Sando, Isao Saito,Scanning of guanine-guanine mismatches in DNA by synthetic ligands using surface plasmon resonance,Nat. Biotechnol.,2001, 19, 51-55.,2001.01.
34. Kazuhiko Nakatani,* Shinya Hagihara, Shinsuke Sando, Hiroshi Miyazaki, Kazuhito Tanabe, Isao Saito*
,Site-selective formation of thymine glycol-containing oligodeoxynucleotides by oxidation with osmium tetroxide and bipyridine-tethered oligonucleotide,J. Am. Chem. Soc.,2000, 122, 6309-6310.
,2000.06.
35. Kazuhiko Nakatani,* Shinsuke Sando, Isao Saito*
,Recognition of a single guanine bulge by 2-acylamino-1,8-naphthyridine,J. Am. Chem. Soc. ,2000, 122, 2172-2177.

,2000.02.
36. Kazuhiko Nakatani,* Shinsuke Sando, Kohzo Yoshida, Isao Saito*,Water-soluble 2-amino-1,8-naphthyridine as a novel DNA binding photosensitizer for one-electron oxidation of DNA,Tetrahedron Lett.,1999, 40, 6029-6032.,1999.08.
37. Kazuhiko Nakatani, Shinsuke Sando, Isao Saito*
,Mechanistic studies on photoinduced cross-linking and specific cleavage at guanine by dibenzoyldiazomethane-oligonucleotide conjugate,Bioorg. Chem. ,1999, 27, 227-237.,1999.06.
38. Kazuhiko Nakatani, Junya Shirai, Shinsuke Sando, Isao Saito*
,Dibenzoyldiazomethane-acridine conjugate: a novel DNA photofootprinting agent,Tetrahedron Lett.,1997, 38, 6047-6050.,1997.08.
39. Kazuhiko Nakatani, Junya Shirai, Shinsuke Sando, Isao Saito*
,Guanine specific DNA cleavage by photoirradiation of dibenzoyldiazomethane-oligonucleotide conjugates,J. Am. Chem. Soc.,1997, 119, 7626-7635.
,1997.08.


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