Kyushu University Academic Staff Educational and Research Activities Database
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Yojiro Arinobu Last modified date:2019.07.13





E-Mail
Homepage
http://www.1nai.med.kyushu-u.ac.jp/
Phone
092-642-5233
Fax
092-642-5247
Academic Degree
M.D., Ph.D.
Field of Specialization
Rheumatology, Allergology
Research
Research Interests
  • Ontogeny of mast cells and basophils
    keyword : mast cell, basophil
    2007.10~2019.03.
Academic Activities
Reports
1. Arinobu Y, Iwasaki H, Akashi K. , Origin of basophils and mast cells., Allergol Int. , 2009.03.
Papers
1. Tsuzuki H, Arinobu Y, Miyawaki K, Takaki A, Ota S, Ota Y, Mitoma H, Akahoshi M, Mori Y, Iwasaki H, Niiro H, Tsukamoto H, Akashi K, Functional interleukin-33 receptors are expressed in early progenitor stages of allergy-related granulocytes, Immunology, 150, 1, 64-73, 2017.01.
2. Miyawaki K, Arinobu Y, Iwasaki H, Kohno K, Tsuzuki H, Iino T, Shima T, Kikushige Y,Takenaka K, Miyamoto T, Akashi K, CD41 marks the initial myelo-erythroid lineage specification in adult mouse hematopoiesis: redefinition of murine common myeloid progenitor., Stem Cells, 33: 976-987, 2015.03.
3. Cantor AB, Iwasaki H, Arinobu Y, Moran TB, Shigematsu H, Sullivan MR, Akashi K, Orkin SH., Antagonism of FOG-1 and GATA factors in fate choice for the mast cell lineage. , J Exp Med. , 17: 611-624, 2008.03.
4. Arinobu Y, Mizuno S, Chong Y, Shigematsu H, Iino T, Iwasaki H, Graf T, Mayfield R, Chan S, Kastner P, Akashi K. , Reciprocal activation of GATA-1 and PU.1 marks initial specification of hematopoietic stem cells into myeloerythroid and myelolymphoid lineages. , Cell Stem Cell , 1: 416-427, 2007.10.
5. Iwasaki H, Mizuno S, Arinobu Y, Ozawa H, Mori Y, Shigematsu H, Takatsu K, Tenen DG, Akashi K. , The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages. , Genes Dev. , 20: 3010-3021, 2006.11.
6. Arinobu Y, Iwasaki H, Gurish M, Mizuno S, Shigematsu H, Ozawa H, Tenen DG, Austen KF and Akashi K. , Developmental checkpoints of the basopohil/mast cell lineages in adult murine hematopoiesis. , Proc Natl Acad Sci USA. , 10.1073/pnas.0509148102, 102, 50, 18105-18110, 102: 18105-18110, 2005.12.
7. Iwasaki H, Mizuno S, Mayfield R, Shigematsu H, Arinobu Y, Seed B, Gurish MF, Takatsu K, and Akashi K. , Identification of eosinophil lineage-committed progenitors in the murine bone marrow. , J Exp Med. , 10.1084/jem.20050548, 201, 12, 1891-1897, 201: 1891-1897, 2005.06.
8. Arinobu Y, Atamas SP, Otsuka T, Niiro H, Yamaoka K, Mitsuyasu H, Niho Y, Hamasaki N, White B, Izuhara K., Antagonistic effects of an alternative splice variant of human IL-4, IL-4δ2 , on IL-4 activities in human monocytes and B cells. , Cell Immunol. , 10.1006/cimm.1998.1431, 191, 2, 161-167, 191: 161-167, 1999.02.
9. Mitsuyasu H, Izuhara K, Mao XQ, Gao PS, Arinobu Y, Enomoto T, Kawai M, Sasaki S, Dake Y, Hamasaki N, Shirakawa T and Hopkin JM. , Ile50Val variant of IL4R alpha upregulates IgE synthesis and associates with atopic ashma. , Nat Genet. , 10.1038/472, 19, 2, 119-120, 19: 119-120, 1998.06.
Presentations
1. 續 啓史, 有信 洋二郎, 宮脇 恒太, IL-33 directly induces inflammatory molecule expression in lineage-committted myeloid progenitors and positively regulates eosinophil hematopoiesis in IL-5-dependent manner., 2015 AAAAI meeting, 2015.02.