Kyushu University Academic Staff Educational and Research Activities Database
List of Papers
Tetsuro Ago Last modified date:2019.06.28

Associate Professor / Department of Medicine and Clinical Science, Graduate School of Medical Sciences / Department of Clinical Medicine / Faculty of Medical Sciences

1. Tachibana M, Ago T, Wakisaka Y, Kuroda J, Kitazono T, Early reperfusion after brain ischemia has beneficial effects beyond rescuing neurons, Stroke, 2017.08.
2. Ago T, Matsuo R, Hata J, Wakisaka Y, Kuroda J, Kitazono T, Kamouchi M. Insulin resistance and clinical outcomes after ischemic stroke., Insulin resistance and clinical outcomes after ischemic stroke., Neurology, 90, 17, 1470-1477, 2018.05.
3. Matsuo R, Yamaguchi Y, Matsushita T, Hata J, Kiyuna F, Fukuda K, Wakisaka Y, Kuroda J, Ago T, Kitazono T, Kamouchi M, Association Between Onset-to-Door Time and Clinical Outcomes After Ischemic Stroke, Stroke, 48, 11, 3049-3056, 2017.11.
4. Matsuo R, Ago T, Kitazono T, Kamouchi M, Short-Term Exposure to Fine Particulate Matter and Risk of Ischemic Stroke, Stroke, 47, 12, 3032-3034, 2016.12.
5. Ogata T, Matsuo R, Kiyuna F, Hata J, Ago T, Tsuboi Y, Kitazono T, Kamouchi M; FSR Investigators., Left Atrial Size and Long-Term Risk of Recurrent Stroke After Acute Ischemic Stroke in Patients with Nonvalvular Atrial Fibrillation. , J Am Heart Assoc, 6, 8, e006402, 2017.08.
6. Wakisaka Y, Matsuo R, Kuroda J, Ago T, Kitazono T, Kamouchi M, Adverse Influence of Pre-Stroke Dementia on Short-Term Functional Outcomes in Patients with Acute Ischemic Stroke: The Fukuoka Stroke Registry, Cerebrovascular diseases, 43, 1-2, 82-89, 2017.06.
7. Sakai Y, Yamamori T, Yoshikawa Y, Bo T, Suzuki M, Yamamoto K, Ago T, Inanami O., NADPH oxidase 4 mediates ROS production in radiation-induced senescent cells and promotes migration of inflammatory cells, Free Radic Res , 52, 1, 92-102, 2018.01.
8. Ishikawa H, Wakisaka Y, Matsuo R, Ago T, Kitazono T, Influence of Statin Pretreatment on Initial Neurological Severity and Short-Term Functional Outcome in Acute Ischemic Stroke Patients: The Fukuoka Stroke Registry, Cerebrovasc diseases, 42, 5-6, 395-403, 2016.05.
9. Nishimura A, Ago T, Kuroda J, et al., Detrimental role of pericyte Nox4 in the acute phase of brain ischemia., J Cereb Blood Flow Metab, 36, 6, 1143-1154, 2016.06.
10. Tong X, Khandelwal AR, Wu X, Xu Z, Yu W, Chen C, Zhao W, Yang J, Qin Z, Weisbrod RM, Seta F, Ago T, et al., Pro-atherogenic role of smooth muscle Nox4-based NADPH oxidase, JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 10.1016/j.yjmcc.2016.01.020, 92, 30-40, 2016.03.
11. Nakamura K, Arimura K, Ago T, et al., Possible involvement of basic FGF in the upregulation of PDGFR beta in pericytes after ischemic stroke, BRAIN RESEARCH, 10.1016/j.brainres.2015.11.003, 1630, 98-108, 2016.01.
12. Tong X, Khandelwal AR, Qin Z, Wu X, Chen L, Ago T, et al., Role of smooth muscle Nox4-based NADPH oxidase in neointimal hyperplasia, JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 10.1016/j.yjmcc.2015.11.013, 89, 185-194, 2015.12.
13. Ago T, Sadoshima J., From Contractile Enhancement to Pathological Hypertrophy Angiotensin II-Induced Nox2-Mediated Reactive Oxygen Species, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 10.1016/j.jacc.2015.05.058, 66, 3, 273-277, 2015.07.
14. Makihara N, Ago T, Involvement of platelet-derived growth factor receptor β in fibrosis through extracellular matrix protein production after ischemic stroke, Exp Neurol, 2015.02.
15. Chen L, Xiao J, Kuroda J, Ago T, Both hydrogen peroxide and transforming growth factor beta 1 contribute to endothelial Nox4 mediated angiogenesis in endothelial Nox4 transgenic mouse lines, Biochim Biophys Acta, 2014.12.
16. Kuroda J, Ago T, Nox4 is a major source of superoxide production in human brain pericytes, J Vasc Res, 2014.12.
17. Kuwashiro T, Ago T, Significance of plasma adiponectin for diagnosis, neurological severity and functional outcome in ischemic stroke - Research for Biomarkers in Ischemic Stroke (REBIOS)., Metabolism, 2014.09.
18. Wakisaka Y, Ago T, Plasma S100A12 is associated with functional outcome after ischemic stroke: Research for Biomarkers in Ischemic Stroke., J Neurol Sci. , 2014.05.
19. Matsuo R, Ago T, Impact of the 1425G/A Polymorphism of PRKCH on the Recurrence of Ischemic Stroke: Fukuoka Stroke Registry., J Stroke Cerebrovasc Dis, 2014.02.
20. Shao D, Oka S, Liu T, Zhai P, Ago T, A redox-dependent mechanism for regulation of AMPK activation by Thioredoxin1 during energy starvation., Cell Metab, 2014.02.
21. Matsuo R, Kamouchi M, Ago T, Thrombolytic therapy with intravenous recombinant tissue plasminogen activator in Japanese older patients with acute ischemic stroke: Fukuoka Stroke Registry., Geriatr Gerontol Int., 2013.12.
22. Nakamura A, Ago T, Intensity of anticoagulation and clinical outcomes in acute cardioembolic stroke: the Fukuoka Stroke Registry., Stroke, 2013.11.
23. Kuwashiro T, Sugimori H, Ago T, Predictive role of C reactive protein in stroke recurrence after cardioembolic stroke: the Fukuoka Stroke Registry., BMJ open, 2013.11.
24. Tokami H, Ago T, RANTES has a potential to play a neuroprotective role in an autocrine/paracrine manner after ischemic stroke., Brain Research, 2013.06.
25. Kuwashiro T, Sugimori H, Ago T, The impact of predisposing factors on long-term outcome after stroke in diabetic patients: the Fukuoka Stroke Registry., Eur J Neurol. , 2013.06.
26. Matsushima S, Kuroda J, Ago T, Broad Suppression of NADPH Oxidase Activity Exacerbates Ischemia/Reperfusion Injury Through Inadvertent Downregulation of Hypoxia-inducible Factor-1α and Upregulation of Peroxisome Proliferator-activated Receptor-α., Circulation Research, 2013.04.
27. Matsuo R, Ago T, Clinical significance of plasma VEGF value in ischemic stroke - research for biomarkers in ischemic stroke (REBIOS) study., BMC Neurology, 2013.04.
28. Matsushima S, Kuroda J, Ago T, Increased oxidative stress in the nucleus caused by Nox4 mediates oxidation of HDAC4 and cardiac hypertrophy., Circulation Research, 2013.02.
29. Ishitsuka K, Ago T(Corresponding author), Arimura K, Nakamura K, Tokami H, Makihara N, Kuroda J, Kamouchi M, Kitazono T., Neurotrophin production in brain pericytes during hypoxia: a role of pericytes for neuroprotection, Microvascular Research, 83, 3, 352-9, 2012.05.
30. Kuwashiro T, Kamouchi M, Ago T, Hata J, Sugimori H, Kitazono T, The factors associated with a functional outcome after ischemic stroke in diabetic patients: the Fukuoka Stroke Registry, J Neurol Sci, 313, 1-2, 110-4, 2012.02.
31. Kuwashiro T, Sugimori H, Ago T, Kamouchi M, Kitazono T; FSR Investigators, Risk factors predisposing to stroke recurrence within one year of non-cardioembolic stroke onset: the Fukuoka Stroke Registry, Cerebrovasc Dis, 33, 2, 141-9, 2012.02.
32. Arimura K, Ago T(Corresponding author), Kamouchi M, Nakamura K, Ishitsuka K, Kuroda J, Sugimori H, Ooboshi H, Sasaki T, Kitazono T., PDGF receptor β signaling in pericytes following ischemic brain injury, Current Neurovascular Research, 9, 1, 1-9, 2012.02.
33. Kamouchi M, Matsuki T, Hata J, Kuwashiro T, Ago T, Sambongi Y, Fukushima Y, Sugimori H, Kitazono T; FSR Investigators, Prestroke glycemic control is associated with the functional outcome in acute ischemic stroke: the Fukuoka Stroke Registry, Stroke, 42, 10, 2788-94, 2011.10.
34. Kuroda J, Ago T, Matsushima S, Zhai P, Schneider MD, Sadoshima J, NADPH oxidase 4 (Nox4) is a major source of oxidative stress in the failing heart., PNAS, 107, 35, 15565-70, 2010.08.
35. Ago T, Kuroda J, Pain J, Fu C, Li H, Sadoshima J., Upregulation of Nox4 by Hypertrophic Stimuli Promotes Apoptosis and Mitochondrial Dysfunction in Cardiac Myocytes., Circulation Research, 2010.04.
36. Fu C, Wu C, Liu T, Ago T, Zhai P, Sadoshima J, Li H., Elucidation of thioredoxin target protein networks in mouse., 8, 1647, 2009.05.
37. Nakamura K, Kamouchi M, Kitazono T, Kuroda J, Shono Y, Hagiwara N, Ago T, Ooboshi H, Ibayashi S, Iida M., Amiloride inhibits hydrogen peroxide-induced Ca2+ responses in human CNS pericytes., Microvasc Res., 77, 327, 2009.05.
38. Ishikawa E, Ooboshi H, Kumai Y, Takada J, Nakamura K, Ago T, Sugimori H, Kamouchi M, Kitazono T, Ibayashi S, Iida M., Midkine gene transfer protects against focal brain ischemia and augments neurogenesis., J Neurol Sci. , 285, 78, 2009.05.
39. Ago T, Yeh I, Yamamoto M, Schinke-Braun M, Brown JA, Tian B, Sadoshima J. , Thioredoxin1 Upregulates Mitochondrial Proteins Related to Oxidative Phosphorylation and TCA Cycle in the Heart., Antioxid Redox Signal , 8(9-10), 1635-1650., 2006.09.
40. Ago T, Kitazono T, Kuroda J, Kumai Y, Kamouchi M, Ooboshi H, Wakisaka M, Kawahara T, Rokutan K, Ibayashi S, Iida M, NAD(P)H oxidases in rat basilar arterial endothelial cells, Stroke, 10.1161/01.STR.0000163111.05825.0b, 36, 5, 1040-1046, 36(5): 1040-1046 , 2005.05.
41. Ago T, Kitazono T, Ooboshi H, Iyama T, Han YH, Takada J, Wakisaka M, Ibayashi S, Utsumi H, Iida M. , Nox4 as the major catalytic component of an endothelial NAD(P)H oxidase., Circulation, 10.1161/01.CIR.0000105680.92873.70, 109, 2, 227-233, 109(2): 227-233., 2004.01.
42. Ago T, Kuribayashi F, Hiroaki H, Takeya R, Ito T, Kohda D, Sumimoto H. , Phosphorylation of p47phox directs PX domain from SH3 domain towards phosphoinositides, leading to phagocyte NADPH oxidase activation. , PNAS, 10.1073/pnas.0735712100, 100, 8, 4474-4479, 100(8): 4474-9., 2003.04.
43. Ago T, Takeya R, Hiroaki H, Kuribayashi F, Ito T, Kohda D, Sumimoto H., The PX domain as a novel phosphoinositide-binding module., Biochem Biophys Res Commun , 10.1006/bbrc.2001.5629, 287, 3, 733-738, 287, 733-8 , 2001.09.
44. Hiroaki H, Ago T, Ito T, Sumimoto H, Kohda D. , Solution structure of the PX domain, a target of the SH3 domain. , Nature Structural Biology, 10.1038/88591, 8, 6, 526-530, 8, 526-30 , 2001.08.
45. Ago T, Nunoi H, Ito T, Sumimoto H., Mechanism for phosphorylation-induced activation of the phagocyte NADPH oxidase protein p47phox. Triple replacement of serines 303, 304, and 328 with aspartates disrupts the SH3 domain-mediated intramolecular interaction in p47phox, thereby activating the oxidase. , J Biol Chem , 10.1074/jbc.274.47.33644, 274, 47, 33644-33653, 274(47): 33644-33653., 1999.11.