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Yoshiko Miura Last modified date：2013.5.14

Professor / Department of Chemical Systems and Engineering, Graduate School of Engineering, Graducate School of Engineering,
Department of Chemical Engineering
Faculty of Engineering


Graduate School
Department of Chemical Systems and Engineering
Graduate School of Engineering
Undergraduate School
Department of Materials Science and Engineering
School of Engineering


E-Mail
Homepage
[URL].
Phone
092-802-2749
Fax
092-802-2769
Academic Degree
Dr of Engineering
Field of Specialization
Biopolymers
Outline Activities

My research major is polymer material, biopolymers and interface science. Based on the major, the following topics are carried out.
(1) Development of glycopolymer
The saccharides on the cell surfaces play important role in the living system as biosignals. The polymers carrying pendant saccharide showed the strong molecular recognition abilities. The molecular recognition abilities of glycopolymers are decided by the saccharide structure and polymer structure. The glycopolymers with protein, virus and toxic protein recognition abilities were developed. We are studying the materials and devices with glycopolymers.
(2) Functional Interface with Dendritic Polymer
Function of interface is deceided by the molecular structure of interface, morphology and the functional groups. The polymer interface with well-defined structure showed the unique properties based on the molecular structure and functional group. We chose the dendrimer as well-defined polymer, and prepared the polymer interface.
(3) Metal Complex with polymer nanoparticle
Polymer nanoparticles or dendrimers were used for the template of metal deposition. The metal, specially Pd, was immobilized and the complex materials were used for catalysis and reactore
Research
Research Interests
  • Catalysis　with Polymer nanogel
    keyword : Polymer, Nanogel, Catalysis
    2012.04～2014.03.
  • The material fabrication with branched polymer interface
    keyword : Interface, Branched Polymer
    2007.04～2013.03.
  • Biomaterials with Glycopolymer
    keyword : Glycopolymer、Biopolymer, Infection Disease
    2008.04～2013.03.
Academic Activities
Books
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Reports
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Papers
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1. Seto, Hirokazu; Ogata, Yutaro; Murakami, Tatsuya; Hoshino, Yu; Miura, Yoshiko ,Selective Protein Separation Using Siliceous Materials with a Trimethoxysilane-Containing Glycopolymer,ACS Applied Materials & Interfaces,Vol.4,No.1,pp.411-417,2012, 4(1), 411-417,2012.01.
2. Matsumoto, Erino; Nishizawa, Kazuki; Fukuda, Tomohiro; Takai, Madoka; Miura, Yoshiko,Separation capability of proteins using microfluidic system with dendrimer modified surface ,Transactions of the Materials Research Society of Japan,Vol.36,No.4,pp.541-544,2011、36（4）、541-544,2011.11.
3. Masaya Wada, Yuta Miyazawa, Yoshiko Miura,A specific Inhibitory effect of multivalent trehalose toward amyloid beta (1-40) aggregation,Polymer Chemistry,accepted,2011.07.
4. Erino Matsumoto, Tomohiro Fukuda, Yoshiko Miura,Bioinert surface to protein adsorption with higher generation of dendrimer SAMs,Colloids and Surfaces B:Biointerfaces,Vol.84,No.1,pp.280-284,2011.05. .
5. Jin Ishii, Masayuki Toyoshima, Miyuki Chikae, Yuzuru Takamura, Yoshiko Miura
,Preparation of Glycopolymer-modified Gold Nanoparticles and a New Approach for a Lateral Flow Assay,Bull chem Soc Jpn,Vol.84,No.5,pp.466-470,selected paper,2011.05. .
6. Tomohiro Fukuda, Erino Matsumoto, Nobuhiko Yui,and Yoshiko Miura,Peculiar Wettability Based on Orientational Change of Self-assembled Hemispherical PAMAM Dendrimer Layer,Chemistry Letters,Vol.39,No.9,pp.923,2010, 39, 923-925,2010.07
[URL]. .
7. T. Fukuda, E. Matsumoto, S. Onogi, Y. Miura,Aggregation of Alzheimer Amyloid β Peptide (1-42) on the Multivalent Sulfonated Sugar Interface,Bioconjugate Chemistry,Vol.21,No.6,pp.1079,2010, 21, 1079-1086,2010.06
[URL]. .
8. M. Toyoshima, T. Oura, T. Fukuda, E. Matsumoto, Y. Miura, ,Biological specific recognition of glycopolymermodified interfaces by RAFT living radical polymerization,Polymer Journal,Vol.42,pp.172,2010, 42, 172-178,2010.02
[URL]. .
9. yoshiko miura,Inhibition of protein amyloidosis by glycomaterials,Trends in Glycoscience and Glycotechnology,Vol.21,No.122,pp.324-334,2009.12.
10. Koji Funato, Naoto Shirahata, Yoshiko Miura,The monolayer of a-Man via Si-C bond formation and protein recognition,Thin Solid Films,Vol.518,pp.699,2009.11.
11. Tomohiro Fukuda, Shunsuke Onogi, Yoshiko Miura,Dendritic Sugar-Microarrays by Click Chemistry,Thin Solid Films,Vol.518,pp.880-888,2009.11.
12. Yoshiko Miura, Kiyofumi Yamamoto, Kikuko Yasuda, Yoshihiro Nishida, Kazukiyo koabayashi,Inhibition of Alzheimer Amyloid Aggregation with Sulfate Glycopolymers,Advances in Science and Technology ,Vol.57,pp.166-169,2009.08.
13. Erino Matsumoto, Takanori Yamauchi, Tomohiro Fukuda, Yoshiko Miura,Sugar microarray by click chemistry,Sci. Technol. Adv. Mater. ,Vol.10,pp.034605,2009.03.
14. Masayuki Toyoshima, Yoshiko Miura,Preparation of GLycopolymer-Substituted Gold nanoparticles and Their Molecular Recognition,Journal of Polymer Science PartA: Polymer Chemistry,Vol.47,pp.1412-1421,2009.03.
15. Miyuki Chikae, Tomohiro Fukuda, K. Kerman, K. Idegami, Yoshiko Miura, Eiichi Tamiya,Amyloid beta-detection with saccharide immobilized gold nanoparticle on carbon electrode,Bioelectrochemistry,Vol.74,pp.118-123,2008.11.
16. Yoshiko Miura, Takahiro Yamauchi, Hajime Sato, Tomohiro Fukuda,The Self-Assembled Monolayer of Saccharide via Click Chemistry: Formation and Protein Recognition,Thin Solid Films,Vol.516,pp.2443,2008.09.
17. Yoshiko Miura, Chouga You, Reiko Ohnishi,,Inhibition of Alzheimer amyloid beta aggregation by polyvalent trehalose,Sci. Technol Adv Mat ,Vol.9,pp.24407,2008.07.
18. Tomohiro Fukuda, Shunsuke Onogi, Yoshiko Miura,Preparation and Properties of Dendritic Sugar Immobilized Surface,Trans. Mat. Res. Soc. Jpn,,Vol.33,pp.733,2008.03.
19. Yoshiko Miura, Shunsuke Onogi, Kiyofumi Yamamoto,Synthesis of Glycodendrimer via Click Chemistry and Protein Affinities,Trans. Mat. Res. Soc. Jpn,Vol.33,pp.729,2008.03.
20. Yoshiko Miura, Kikuko Yasuda, Kiyofumi Yamamoto, Mihoko Koike, Yoshihiro Nishida, Kazukiyo Kobayashi,Inhibition of Alzhimer Amyloid Aggregation with Sulfated Glycopolymers ,Biomacromolecules,Vol.8,pp.2129,2007.11.
21. Yoshiko Miura, Daisuke Kouketsu, kazukiyo Kobayashi,Synthesis and Properties of a Well-Defined Glycopolymer via Living radical Polymerization,Polymer Advanced Technology,Vol.18,pp.647,2007.07.
22. Hajime Sato, Yoshiko Miura, Nagahiro Saito, Kazukiyo Kobayashi, Osamu Takai,Fibroblastic Microfabrication by Molecular Recognition on Substrate,Surface Science,Vol.601,pp.3871,2007.04.
23. Hajime Sato, Yoshiko Miura, Nagahiro Saito, Kazukiyo Kobayashi, Osamu Takai,A Micropatterned Multifunctional Carbohydrate Display by an Orthogonal Self-Assembling Strategy,Biomacromolecules,Vol.8,pp.753-756,2007.01.
24. Yoshiko Miura, Akio Sakaki, Masamichi Kamihira, Shinji Iijima, Kazukiyo Kobayashi,A globotriaosylceramide (Gb3Cer) mimic peptide ,Biochimica et Biophysica Acta,Vol.1760,pp.883,2006.09.
25. Hajime Sato, Yoshiko Miura, Takahiro Yamauchi, Kazukiyo ,Carbohydrate Microarray by Click Chemistry,Trans. Mat. Res. Soc. Jpn,Vol.31,pp.659,2006.04.
26. Yoshiko Miura,The Development and the Character of Saccharide Biosensors,Trends in Glycoscience and Glycotechnology, ,Vol.18,pp.349,2006.04.
27. Yoshiko Miura, Chieri Shibata, Kazukiyo Kobayashi,Theremoresponsive Self-Assembly of Short Elastin-Like Peptides ,Trans Mat Res Soc Jpn,Vol.31,pp.549,2006.04.
28. Yoshiko Miura, Chieri Shibata, Kazukiyo Kobayashi,Theremoresponsive Self-Assembly of Short Elastin-Like Peptides ,Trans Mat Res Soc Jpn,Vol.31,pp.549,2006.04.
29. Natsuko Wada, Yoshiko Miura, Kazukiyo Koabayashi,Synthesis and Biological Properties of Glycopolymer-Polylactide Conjugate,Trans. Mat. Res. Soc. Jpn,Vol.32,pp.767,2005.04.
30. Yoshiko Miura, Natsuko Wada, Yoshihiro Nishida, H. Mori, K. Kobayashi,Chemoenzymatic Synthesis of Glycoconjugate Polymers Starting from Non-reducing Disaccharides,J. Polym. Sci. part A Polym. Chem. 2004, 42, 4598,Vol.42,pp.4598,2004.04.
31. Yoshiko Miura, Yuki Sasao, Masamichi Kamihira, Akio Sakaki, Shinji Iijima, Kazukiyo kobayashi,Peptides binding to a Gb3 mimic selected from a phage library,Biochem. Biophys. Acta,Vol.1673,pp.131,2004.04.
32. Y. Miura, T. Ikeda, N. Wada, K. Kobayashi,Chemoenzymatic synthesis of a Multivalent Aminoglycoside,Macromol. Biosci,Vol.3,pp.362,2003.04.
33. Y. Miura, T. Ikeda, N. Wada, K. kobayashi,Chemoenzymatic Synthesis of Glycoconjugate Polymers: Greening the Synthesis of biomaterials,Green Chemistry,Vol.5,pp.610,2003.04.
34. Yoshiko Miura, takayasu ikeda, kazukiyo kobayashi,Chemoenzymatically Synthesized Glycoconjugate Polymers,Biomacromolecules,Vol.4,No.2,pp.410,2003.02.
35. Yoshiko Miura, Yuuki Sasao, Hirofumi Dohi, Yoshihiro Nishida and Kazukiyo Kobayashi,Self-assembled monolayers of globotriaosylceramide (Gb3) mimics: surface-specific affinity with shiga toxins ,Vol.310,pp.27,2002.04.
36. Y. Miura, S. Kimura, S. Kobayashi, Y. Imanishi, J. Umemura,Cation recognition by self-assembled monolayers of oriented helical peptides having a crown ether unit,Biopolymers,Vol.55,pp.391,2000.04.
37. Y. Miura, S. Kimura, Y. Imanishi, J. Umemura,Self-Assembly of a-helix peptide/crown ether conjugate upon complexation with ammonium-terminated alkanethiolate,Vol.14,pp.2761,1998.04.
38. Y. Miura, S. Kimura, Y. Imanishi, J. Umemura,Formation of Oriented Helical Peptide Layers on a Gold Surface due to the Self-assembling Properties of Peptides,Langmuir,Vol.14,pp.6935,1998.04.
Presentations
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Membership in Academic Society
  • The Society of Chemical Engineering, Japan
  • the Materials Research Society of Japan
  • Polymer Society Japan
  • The Chemical Society of Japan
  • The Japan Society of Applied Physics
  • American Chemical Society
Awards
  • The manuscript title of "Interaction Analyses of Amyloid beta Peptide (1-40)　with Glycosaminoglycan Model Polymers" was selected as BCSJ award by Japan Chemical Society. In this manuscript, the author described the inhibition of Alzheimer disease using biomaterials. Especially, the authors synthesized glycominoglycan mimic polymer which inhibit the aggregation of Alzheimer amyloid beta aggregation.
Social
Professional and Outreach Activities
JGFos (2004)


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