| Hikasa Hiroki | Last modified date：2013.6.3 |
E-Mail
Phone
092-642-6838
Fax
092-632-1499
Academic Degree
Ph.D
Field of Specialization
developmental biology, molecular biology
Research
Research Interests
Membership in Academic Society
- The study on the molecular mechanism for the activation of Hippo signaling pathway in response to extracellular signal
keyword : Hippo signaling pathway
2010.10. - The study on the molecular mechanism for the activation of Hippo signaling pathway in response to extracellular signal
keyword : Hippo signaling pathway
2010.10.
- The TCF3 phosphorylation mediated by Wnt/HIPK2 signal attenuates the affinity of TCF3 for the target DNA, leading to the de-repression of the target genes. Next, we address the questions "What components are upstream of HIPK2?" and "How is HIPK2 activated?"
Reports
| 1. | Hiroki Hikasa and Sergei Y. Sokol,Wnt signaling in vertebrate axis specification,Cold Spring Harb Perspect Biol,2012.10. |
Papers
| 1. | Hikasa H, Sokol SY.,Phosphorylation of TCF proteins by homeodomain-interacting protein kinase 2.,J Biol Chem.,Vol.286,No.14,pp.12093-100,2011.04. |
| 2. | Hikasa H., Ezan J., Itoh K., Li X., Klymkowsky M. W. and Sokol S. Y.,Regulation of TCF3 by Wnt-dependent phosphorylation during vertebrate axis specification,Developmental Cell,Vol.19,No.4,pp.521-32,2010.10. |
- The molecular biology society of Japan
- Japanese Society of Developmental Biologist
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