Kyushu University Academic Staff Educational and Research Activities Database
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KAORU TAMADA Last modified date:2018.06.20

Graduate School
Administration Post
Vice President

研究室HP .
Academic Degree
Doctor of Science
Field of Specialization
Surface Physical Chemistry
Research Interests
  • The development of a fluidic laser via the coupling of semiconductor nanostructures with a self-assembled optical cavity
    keyword : quantum dots, plasmon, micro-fluid cell, biosensing
  • Creation of complex 3D nanometamaterials
    keyword : Metallic nanoparticles, self-asssembly, plasmonics, metamaterial
Current and Past Project
  • The primary objective of this project is to achieve room temperature lasing within a microfluidic channel by coupling a solution of colloidal semiconductor quantum dots (QDs) capable of exhibiting strong optical gain with plasmonic nano-cavities formed via the self-assembly of highly uniform metal nanoparticles. Such a fluidic QD-nanoplasmonic laser will be the first of its kind and will eventually be developed into a nonlinear biosensing platform with extremely small detection volumes (e.g. picolitres) and sensitivity much higher than that of fluorescence-based detection strategies.
    The motivation to use QDs is attributed to their many distinct advantages over conventionally used dyes, such as high resistance to photobleaching, flexible surface chemistry and so on. The self-assembled metal nanoparticle structures will serve as a plasmonic resonator, which allows for optical feedback, thereby allowing for lasing to be achieved. Because the gain medium is in a solution phase rather than in the solid state as conventionally used, the optical gain and threshold characteristics of such a laser are dynamically configurable.
  • 1. Background of research
    Recently localized surface plasmon resonance (LSPR) with metallic nanoparticles has been studied extensively to develop highly sensitive biosensing devices. However it was difficult to fabricate large sized regular arrays on surface composed of metallic nanoparticles before our study.
    2. Research objectives
    To fabricate multidimensional, complex structured metallic nanoparticle sheet for fluorescence enhancement. This sheet can be used as disposable substrates for the fluorescence imaging with a regular optical microscope and give more than 10 times stronger emission. We will apply this technique to various life innovations.
    3. Research characteristics (incl. originality and creativity)
    In our previous study, we have succeeded in a fabrication of homogeneous 2D crystalline sheet composed of Ag nanoparticles by self-assembly at air-water interface. This sheet can excite strong, collective LSPR field on surface. This technique is purely our original. We will extend this self-assembling technique to the fabrication of multidimensional, complex films in order to obtain further stronger electromagnetic field.
    4. Anticipated effects and future applications of research
    We would like to contribute to advanced bio-medical field by applying our fluorescence enhancement technique to tumor marker detections, which have low detection limits. Because our LSPR sheet keeps nano-spatial resolution, the sheet can be applied to a single molecular imaging, too, unlike the conventional propagating SPR.
Academic Activities
1. Eiji Usukura, Yuhki Yanase, Ayumi Ishijima, Thasaneeya Kuboki, Satoru Kidoaki, Koichi Okamoto, Kaoru Tamada, LSPR-mediated high axial-resolution fluorescence imaging on a silver nanoparticle sheet, PLoS One, 10.1371/journal.pone.0189708, 12, 12, 2017.12, This paper reports our original technique for visualizing cell-attached nanointerfaces with extremely high axial resolution using homogeneously excited localized surface plasmon resonance (LSPR) on self-assembled silver nanoparticle sheets. The LSPR sheet can confine and enhance the fluorescence at the nanointerface, which provides high signal-to-noise ratio images of focal adhesion at the cell-attached interface. The advantage of this LSPR-assisted technique is its usability, which provides comparable or higher-quality nanointerfacial images than TIRF microscopy, even under epifluorescence microscopy. We also report the cytotoxicity of silver nanoparticles, as determined via morphological analysis of adherent cells on the sheet..
2. S. Masuda, Y. Yanase, E. Usukura, S. Ryuzaki, K. Okamoto, KUBOKI THASANEEYA, S. Kidoaki, Kaoru Tamada, High-resolution imaging of a cell- attached nanointerface using a gold-nanoparticle two-dimensional sheet, Sci. Rep., 7, 3720, 1-10, 2017.07, This paper proposes a simple, effective, non-scanning method for the visualization of a cell-attached nanointerface. The method uses localized surface plasmon resonance (LSPR) excited homogeneously on a two-dimensional (2D) self-assembled gold-nanoparticle sheet. The LSPR of the gold-nanoparticle sheet provides high-contrast interfacial images due to the confined light within a region a few tens of nanometers from the particles and the enhancement of fluorescence. Test experiments on rat basophilic leukemia (RBL-2H3) cells with fluorescence-labeled actin filaments revealed high axial and lateral resolution even under a regular epifluorescence microscope, which produced higher quality images than those captured under a total internal reflection fluorescence (TIRF) microscope. This non-scanning-type, high-resolution imaging method will be an effective tool for monitoring interfacial phenomena that exhibit relatively rapid reaction kinetics in various cellular and molecular dynamics..
3. Z-Y. Juang, C-C Tseng, Y. Shi, W-P Hsieh, Sou Ryuzaki, N. Saito, C.-E Hsiung, Y. Hernandez, Y. Han, Kaoru Tamada, L-J L, Graphene-Au nanoparticle based vertical heterostructures: A novel route towards high-ZT Thermoelectric devices, Nano Energy, 38, 385-391, 2017.04.
4. K. Okamoto, D. Tanaka, R. Degawa, X. Li, PANGPANG WANG, Sou Ryuzaki, Kaoru Tamada, Electromagnetically induced transparency of a plasmonic metamaterial light absorber based on multilayered metallic nanoparticle sheets, Sci. Rep. , 6, 36165, 2016.09.
5. Ryo degawa, Pangpang Wang, Daisuke Tanaka, S. Park, N.Sakai, T. Tatsuma, Koichi Okamoto, Kaoru Tamada, Colorimetric detection of an airborne remote photocatalytic reaction using a stratified Ag nanoparticle Sheet, Langmuir, 32, 8154-8162, 2016.04.
6. Pangpang Wang, Daisuke Tanaka, Shohei Araki, K. Okamoto, Kaoru Tamada, Silver nanoparticles with tunable work functions, Applied Physics Letters, 107, 151601-1-151601-5, 2015.10.
7. Daisuke Tanaka, Keisuke Imazu, Jinwoo Sung, Cheolmin Park, K. Okamoto, Kaoru Tamada, Characteristics of localized surface plasmons excited on mixed monolayers composed of self-assembled Ag and Au nanoparticles, Nanoscale, DOI: 10.1039/c5nr03601a, 7, 15310-15320, 2015.06.
8. Shuhei Shinohara, Daisuke Tanaka, Koichi Okamoto, Kaoru Tamada, Colorimetric plasmon sensors with multilayered metallic nanoparticle sheets, Phys. Chem. Chem. Phys., 17, 18606-18612, 2015.07.
9. PANGPANG WANG, Koichi Okamoto, Kaoru Tamada, Tuning the work functions of two-dimensional silver nanoparticle sheets using local oxidation nanolithography, Adv. Mater. Interfaces, 1400268, 2014.12.
10. E. Usukura, S. Shinohara, K. Okamoto, J. Lim, K. Char, K. Tamada, Highly confined, enhanced surface fluorescence imaging with two-dimensional silver nanoparticle sheets, Applied Physics Letters, 104, 121906, 2014.03.
11. Koichi Okamoto, Brian Lin, Keisuke Imazu, Akihito Yoshida, Koji Toma, Mana Toma, Kaoru Tamada, Tuning colors of silver nanoparticle sheets by multilayered crystalline structures on metal substrates, Plasmonics, 8, 581, 2013.04.
12. Akihito Yoshida, Keisuke Imazu, Xinheng Li, Koichi Okamoto, Kaoru Tamada, Spectroscopic Properties of Multilayered Gold Nanoparticles 2D Sheets, Langmuir, 28, 17153, 2012.11.
13. Kim HW, Jung J, Han MN, Lim S, Tamada K, Hara M, Kawai M, Kim Y, Kuk Y , One-Dimensional Molecular Zippers , J. Am. Chem. Soc., 10.1021/ja2031486, 133, 24, 9236-9238, 2011.04.
14. Mana Toma, Koji Toma, Kanae Michioka, Yasuhiro Ikezoe, Daiki Obara, Koichi Okamoto and Kaoru Tamada, Collective plasmon modes excited on a silver nanoparticle 2D crystalline sheet, Phys. Chem. Chem. Phys., 10.1039/c0cp02953j, 13, 7459-7466, 2011.02.
15. Kim HW, Han, M, Shin HJ, Lim S , Oh Y, Tamada K , Hara M , Kim Y, Kawai M, Kuk Y, Control of Molecular Rotors by Selection of Anchoring Sites , Phys. Rev. Lett., 10.1103/PhysRevLett.106.146101, 106, 14, 146101, 2011.01.
16. Satoshi Katano, Koji Toma, Mana Toma, Kaoru Tamada and Yoichi Uehara, Nanoscale coupling of photons to vibrational excitation of Ag nanoparticle 2D array studied by scanning tunneling microscope light emission spectroscopy, Phys. Chem. Chem. Phys., 10.1039/c0cp01005g, 12, 44, 14749-14753, 2010.08.
17. T. Nagahiro, K. Ishibashi, Y. Kimura, M. Niwano, T. Hayashi, Y. Ikezoe, M. Hara, T. Tatsuma, K. Tamada, Ag nanoparticle sheet as a marker of lateral remote photocatalytic reaction, Nanoscale, 10.1039/b9nr00240e, 2, 107-113, 2009.11.
18. T. Nagahiro, H. Akiyama, M. Hara, K. Tamada, Photoisomerization of azobenzene containing self-assembled monolayers investigated by Kelvin probe work function measurements, J. Electron Spectroscopy and Related Phenomena, 172, 1-3, 128-133, 2009.07.
19. C.-D. Keum, N. Ishii, K. Michioka, K. Tamada, M. Hara, M. Furusawa, H. Fukushima, A Gram Scale Synthesis of Monodispersed Silver Nanoparticles Capped by Carboxylate and Their Ligand Exchange, J. Nonlinear Optical Physics & Materials, 17, 131-142, 2008.07.
20. Ito M, Nakamura F, Baba A, Tamada K, Ushijima H, Lau KHA , Manna A, Knoll W, Enhancement of surface plasmon resonance signals by gold nanoparticles on high-density DNA microarrays, J. Phys. Chem. C, 111, 31, 11653-11662, 2007.07.
1. Kaoru Tamada, Electromagnetically induced transparency of a plasmonic metamaterial light absorber based on multilayered metallic nanoparticle sheet, ICFPAM2016, 2016.11.
2. Kaoru Tamada, Dimensional Optical Property of Self-assembled Metallic Nanoparticles, Pacifichem2015, 2015.12.
3. Kaoru Tamada, Shihomi Masuda, Ayumi Ishijima, Eiji Usukura, Koichi Okamoto, Self-assembled Metallic Nanoparticles for Bioimaging, KJF-ICOMEP2015, 2015.09.
4. Kaoru Tamada, Eiji Usukura, Shihomi Masuda, Koichi Okamoto, Daisuke Tanaka, Yuhki Yanase, High Contrast and High Resolution Cell Imaging by use of Metallic Nanoparticle 2D sheet, ICMAT 2015 & IUMRS-ICA 2015, 2015.07.
5. Kaoru Tamada, 臼倉 英治, Shuhei Shinohara, Daisuke Tanaka, Koichi Okamoto, Highly Confined, Enhanced Surface Fluorescence Imaging with 2D Silver Nanoparticle Sheets, 8th International conference on Energy-Materials-Nanotechnology, 2014.11.
6. Kaoru Tamada, Self-assembled metal nanoparticle based biosensor and bioimaging, ISSS-7国際会議, 2014.11.
7. Kaoru Tamada, Plasmonic Property of Multidimensional Self-assembled Metallic Nanoparticles, 第17回 微粒子と無機クラスターに関する国際シンポジウム(ISSPIC XVII), 2014.09.
8. Kaoru Tamada, Dimensional Optical Property of Self-assembled Metallic Nanoparticles, The 15th IUMRS-International Conference in Asia (IUMRS-ICA 2014), 2014.08.
Membership in Academic Society
  • MRS of Singapore
  • American Chemical Society
  • The Chemical Society of Japan
  • The Surface Science Society of Japan
  • The Japan Society of Applied Physics
  •  Self-assembly of molecules and nanomaterials