Kyushu University Academic Staff Educational and Research Activities Database
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Tomotake Tokunou (Tokuno) Last modified date:2019.12.06

Assistant Professor / Internal Medicine
Kyushu University Hospital

Academic Degree
Field of Specialization
Research Interests
  • Treatment of heart failure and peripheral vascular disease by hyperthermia
    keyword : peripheral vascular disease, heart failure
  • Anti-inflammation by hypoxia signaling
    keyword : hypoxia, HIF
  • Hypoxic response with sleep apnea syndrome
    keyword : Sleep apnea syndrome, hypoxia
  • Regeneration and repair of cardiovascular tissue
    keyword : tissue repair, growth factors
Academic Activities
1. Kojima H, Tokunou T, Takahara Y, Sunagawa K, Hirooka Y, Ichiki T, Tsutsui H., Hpoxia-inducible factor-1α deletion in myeloid lineage attenuates hypoxia-induced pulmonary hypertension., Physiological Reports, 10.14814/phy2.14025., 7, 7, e14025, 2019.04.
2. Higuchi Y, Niidome T, Miyamoto Y, Komohara Y, Tokunou T, Kubota T, Horiuchi T., Accumulation of gold nano-rods in the failing heart of transgenic mice with the cardiac-specific expression of TNF-α., Heart and Vessels, 34, 538-544, 2019.03.
3. Takahara Y, Tokunou T, Ichiki T, Suppression of Abdominal Aortic Aneurysm Formation in Mice by Teneligliptin, a Dipeptidyl Peptidase-4 Inhibitor., J Atheroscler Thromb., 10.5551/jat.42481., 2018.01.
4. Takahara Y, Tokunou T, Kojima H, Hirooka Y, Ichiki T., Deletion of Hypoxia-Inducible Factor-1α in Myeloid Lineage Exaggerates Angiotensin II-Induced Formation of Abdominal Aortic Aneurysm., Clin Sci (Lond)., 131, 7, 609-620, 2017.04.
1. Tomotake Tokunou, Toyoki Maeda, Takahiko Horiuchi, Naoki Makino, Telomere shortening is accelerated in a gender-differential manner in patients with insomnia receiving sleep medication., 5th Asean Sleep Federation Congress, 2019.11.