Kyushu University Academic Staff Educational and Research Activities Database
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Gaku Tsuji Last modified date:2019.07.29



Graduate School


E-Mail
Phone
092-642-5585
Fax
092-642-5590
Academic Degree
Ph.D.
Field of Specialization
Dermatology
Research
Research Interests
  • The role of autophagy in the skin
    keyword : autophagy
    2018.01~2020.03.
  • The roles of aryl hydrocarbon receptor of the skin
    keyword : Aryl Hydrocarbon Receptor
    2007.04~2017.03.
Academic Activities
Reports
1. Tsuji G, Ito T, Chiba T, Mitoma C, Nakahara T, Uchi H, Furue M., The role of the OVOL1-OVOL2 axis in normal and diseased human skin., J Dermatol Sci., 2018.06.
Papers
1. Takemura M, Nakahara T, Hashimoto-Hachiya A, Furue M, Tsuji G., Glyteer, Soybean Tar, Impairs IL-4/Stat6 Signaling in Murine Bone Marrow-Derived Dendritic Cells: The Basis of Its Therapeutic Effect on Atopic Dermatitis., Int J Mol Sci. , 2018.04.
2. Tsuji, Gaku; Hashimoto-Hachiya, Akiko; Takemura, Masaki; Kanemaru, Takaaki; Ichihashi, Masamitsu; Furue, Masutaka, Palladium and Platinum Nanoparticles Activate AHR and NRF2 in Human Keratinocytes-Implications in Vitiligo Therapy, JOURNAL OF INVESTIGATIVE DERMATOLOGY, 10.1016/j.jid.2017.02.981, 137, 7, 1582-1586, 2017.07.
3. Tsuji, Gaku; Hashimoto-Hachiya, Akiko; Kiyomatsu-Oda, Mari; Takemura, Masaki; Ohno, Fumitaka; Ito, Takamichi; Morino-Koga, Saori; Mitoma, Chikage; Nakahara, Takeshi; Uchi, Hiroshi; Furue, Masutaka, Aryl hydrocarbon receptor activation restores filaggrin expression via OVOL1 in atopic dermatitis, CELL DEATH & DISEASE, 10.1038/cddis.2017.322, 8, 2017.07.
4. Takamichi Ito, Gaku Tsuji, Fumitaka Ohno, Hiroshi Uchi, Takeshi Nakahara, Akiko Hachiya, Yuichi Yoshida, Osamu Yamamoto, Oda, Yoshinao, Masutaka Furue, Activation of the OVOL1-OVOL2 Axis in the Hair Bulb and in Pilomatricoma., Am J Pathol, 186, 4, 1036-1043, 2016.04.
5. Gaku Tsuji, Histone deacetylase 6 inhibition impairs effector CD8 T-cell functions during skin inflammation., J Allergy Clin Immunol. , 135(5):1228-1239, 2015.05.
6. Tsuji G, Takahara M, Uchi H, Matsuda T, Chiba T, Takeuchi S, Yasukawa F, Moroi Y, Furue M., Identification of Ketoconazole as an AhR-Nrf2 Activator in Cultured Human Keratinocytes: The Basis of Its Anti-Inflammatory Effect., J Invest Dermatol., 10.1038/jid., 2011.07.
7. Tsuji G, Takahara M, Uchi H, Takeuchi S, Mitoma C, Moroi Y, Furue M., An environmental contaminant, benzo(a)pyrene, induces oxidative stress-mediated interleukin-8 production in human keratinocytes via the aryl hydrocarbon receptor signaling pathway., J Dermatol Sci., 62, 1, 42-49, 2011.04.
Presentations
1. Gaku Tsuji, Akiko Hachiya, 中原 剛士, 三苫 千景, 古江 増隆, AHR regulates FLG expression via OVOL1 in human keratinocytes: A plausible relationship between FLG and OVOL1 in atopic dermatitis, ASDR 2016, 2016.08.
2. Gaku Tsuji, Activation of aryl hydrocarbon receptor-nuclear factor erythroid 2-related factor 2 signaling axis by epidermal growth factor receptor inhibitors: a possible mechanism for acneiform eruption. , 45th Annual ESDR Meeting , 2015.09.
3. Gaku Tsuji, Activation of OVOL1-OVOL2 axis in hair bulb, pilomatricoma and pilomatrix carcinoma., 日本研究皮膚科学会, 2015.12.
4. Gaku Tsuji, Activation of aryl hydrocarbon receptor-nuclear factor erythroid 2-related factor 2 axis by epidermal growth factor receptor inhibitors: a possible mechanism for acneiform eruption., 45TH ANNUAL ESDR MEETING, 2015.09.
5. Gaku Tsuji, Tubacin, a histone deacetylase 6 inhibitor, suppresses contact sensitivity via impairment of the immune synapse. , International Investigative Dermatology 8th, 2013.05.
6. Gaku Tsuji, Cynaropicrin, an extract from artichoke, inhibits UVB-induced oxidative stress in cultured human keratinocytes. , Society of Investigative Dermatology 72nd Annual meeting , 2012.05.
Awards
  • Activation of aryl hydrocarbon receptor-nuclear factor erythroid 2-related factor 2 axis by epidermal growth factor receptor inhibitors: a possible mechanism for acneiform eruption