九州大学 研究者情報
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基本情報 研究活動
原田 結(はらだ ゆい) データ更新日:2019.09.13

准教授 /  薬学研究院 臨床薬学部門 革新的バイオ医薬創成学


主な研究テーマ
悪性腫瘍に対する免疫細胞を用いた治療技術の開発、がん腹膜播種メカニズムの解明、人工肝臓の開発
キーワード:がん、樹状細胞、NK細胞、腹膜播種、人工肝臓
2006.04~2015.09.
研究業績
主要著書
主要原著論文
主要総説, 論評, 解説, 書評, 報告書等
特許出願・取得
特許出願件数  16件
特許登録件数  15件
学会活動
学協会役員等への就任
2011.04~2013.03, 外科分子細胞治療研究会, 幹事.
学会大会・会議・シンポジウム等における役割
2019.04.19~2019.04.19, Japan Surgical Society for Molecular and Cellular Therapy 21st Annual meeting , がん免疫治療の最前線 〜GAIA-102: Allo-NK細胞製剤によるbreakthrough〜.
2019.03.19~2019.03.21, The 3rd Innate Killer Summit, AdoptCell®-NK: a new class NK cells manufactured in accordance with GMP/GCTP that can eliminate the solid tumors.
2018.11.28~2018.11.28, 第7回 ベンチャー創設支援フォーラム, AdoptCell®️-NK:全く新しい養子免疫 〜固形腫瘍治療に適した細胞とは〜 .
2018.11.16~2018.11.17, The 29th Annual Meeting of the Japanese Society for Gastroenterological Carcinogenesis, Development of innovative therapeutics for solid tumors.
2018.11.07~2018.11.11, Society for Immunotherapy of Cancer (SITC) 33rd Anniversary Annual Meeting , AdoptCell®-NK: a new class NK cells manufactured in accordance with GMP/GCTP that can eliminate the solid tumors.
2018.07.26~2018.07.28, The 24th Annual Meeting of JSGCT, GAIA-102: a new class NK cells manufactured in accordance with GMP/GCTP that can eliminate the solid tumors.
2018.05.16~2018.05.19, American society of Gene and Cell Therapy 21st Annual meeting , AdoptCell®-NK: a Novel Natural Killer Cell Phenotype That Can Eliminate the Solid Tumors.
2018.03.21~2018.03.23, The 17th Congress of the Japanese Society for Regenerative Medicine, Viral/transgene/feeder-free iPS cell-based extracorporeal-circulating artificial liver support.
2018.03.21~2018.03.23, The 17th Congress of the Japanese Society for Regenerative Medicine, AdoptCell®-NK: a new class NK cells manufactured in accordance with GMP/GCTP for clinical studies.
2017.11.17~2017.11.18, The 28th Annual Meeting of the Japanese Society for Gastroenterological Carcinogenesis,The 9th International Conference of the Society of Gastroenterological Carcinogenesis, Development of novel NK cell-based immunotherapy for malignancies.
2017.11.08~2017.11.12, Society for Immunotherapy of Cancer (SITC) 32nd Anniversary Annual Meeting, AdoptCell®-NK: Ex vivo generation of highly purified and activated natural killer cells from human peripheral blood in accordance with GMP/GCTP for clinical studies.
2017.07.25~2017.07.27, The 2nd Innate Killer Summit, Ex vivo generation of highly purified and activated natural killer cells from human peripheral blood in accordance with GMP/GCTP for clinical studies.
2017.07.20~2017.07.22, The 23rd Annual Meeting of JSGCT, Artificial liver based on viral/transgene/feeder-free iPS cell-derived functional hepatocytes.
2017.03.07~2017.03.09, The 16th Congress of the Japanese Society for Regenerative Medicine, Viral/transgene/feeder-free iPS cell-based functional hepatocytes.
2016.11.11~2016.11.13, Society for Immunotherapy of Cancer (SITC) 31st Anniversary Annual Meeting, Ex vivo generation of highly purified and activated natural killer cells from human peripheral blood in accordance with GMP/GCTP for clinical studies.
2016.10.14~2016.10.18, The 14th International Symposium on Dendritic Cells, Lung adenocarcinoma may be a more susceptive subtype to a dendritic cell-based cancer vaccine than other subtypes of non-small cell lung cancers: a multicenter retrospective analysis.
2016.09.15~2016.09.16, The 27th Annual Meeting of the Japanese Society for Gastroenterological Carcinogenesis, MEK 1/2 inhibition might be a potential strategy to treat peritoneal dissemination by inhibiting MDSCs.
2016.10.06~2016.10.08, The 75th Japanese Cancer Association, Peritoneal dissemination requires an Sp1-dependent CXCR4/CXCL12 signaling axis and sphere formation.
2016.07.28~2016.07.30, The 22nd Annual Meeting of JSGCT, Peritoneal Dissemination Requires an Sp1-Dependent CXCR4/CXCL12 Signaling Axis and Extracellular Matrix–Directed Spheroid Formation.
2015.11.19~2015.11.20, The 26th Annual Meeting of the Japanese Society for Gastroenterological Carcinogenesis, Development of a novel therapeutic approach based on the mechanism of tumor dissemination.
2015.11.04~2015.11.08, Society for Immunotherapy of Cancer (SITC) 30th Anniversary Annual Meeting, Mass-production of human dendritic cells in accordance with GMP for clinical studies.
2015.07.24~2015.07.26, The 21st Annual Meeting of JSGT, Viral/transgene/feeder-free iPS cell-based functional hepatocytes.
2015.03.08~2015.03.13, Keystone Symposia: Dendritic Cells and Macrophages Reunited (C4), Mass-production of human dendritic cells in accordance with GMP for clinical studies.
2014.11.13~2014.11.14, The 25th Annual Meeting of the Japanese Society for Gastroenterological Carcinogenesis,The 8th International Conference of the Society of Gastroenterological Carcinogenesis, Identification of mesenteric hematopoiesis where is the metastatic niche of tumor dissemination.
2014.09.25~2014.09.27, The 73rd Japanese Cancer Association, Molecular and Cellular Mechanism of Directed Tumor Dissemination in the Peritoneal Cavity.
2014.09.14~2014.09.18, The 13th International Symposium on Dendritic Cells, Mass-production of human dendritic cells in accordance with GMP for clinical studies.
2014.08.06~2014.08.08, The 20th Annual Meeting of JSGT, Molecular and cellular mechanism of tumor dissemination in the peritoneal cavity.
2013.10.25~2013.10.28, The 22nd European Society of Gene and Cell Therapy, Molecular and Cellular Mechanism of Tumor Dissemination in the Peritoneal Cavity.
2013.10.03~2013.10.05, The 72nd Japanese Cancer Association, 腹膜播種がん幹細胞様細胞が足場とするニッシェ様細胞の同定とその標的化.
2013.06.04~2013.06.06, The 19th Annual Meeting of JSGT, Identification of mesenteric hematopoiesis where is the metastatic niche of tumor dissemination.
2012.10.07~2012.10.11, The 12th International Symposium on Dendritic Cells, Cytokine-based log-scale expansion of functional human dendritic cells of cancer patients.
2011.10.17~2011.10.20, The 2nd Meeting of ACTO, Cytokine-based log-scale expansion of functional human dendritic cells from PBMC.
2011.07.15~2011.07.17, The 17th Annual Meeting of JSGT, Cytokine-based log-scale expansion of functional human dendritic cells from PBMCs.
2011.05.18~2011.05.21, American society of Gene and Cell Therapy 14th Annual meeting, Cytokine-based log-scale expansion of functional human dendritic cells from PBMCs.
2010.09.26~2010.09.30, The 11th International Symposium on Dendritic Cells, Cytokine-based log-scale expansion of functional human dendritic cells.
2010.07.01~2010.07.03, The 16th Annual Meeting of JSGT, Search for a key molecule of dendritic cell differentiation.
2010.07.22~2010.07.23, 第14回日本がん免疫学会, Cytokine-based log-scale expansion of functional human dendritic cells.
2010.05.19~2010.05.22, American society of Gene and Cell Therapy 13th Annual meeting, Cytokine-based log-scale expansion of functional human dendritic cells.
2009.07.09~2009.07.11, The 15th Annual Meeting of JSGT, Cytokine-based log-scale expansion of functional human dendritic cells.
2008.10.01~2008.10.05, The 10th International Symposium on Dendritic Cells, Young Investigator Award候補演題 (English Presentation).
2008.07.19~2008.07.21, 11th LIPOSOME RESEARCH DAYS CONFERENCE, Cytokine-based log-scale expansion of functional murine dendritic cells.
2008.06.12~2008.06.14, The 14th Annual Meeting of JSGT, Cytokine-based log-scale expansion of functional murine dendritic cells .
2008.05.28~2008.06.01, American society of Gene Therapy 11th Annual meeting, Cytokine-based log-scale expansion of functional murine dendritic cells .
2007.06.28~2007.06.30, The 13th Annual Meeting of JSGT, Generation of a large number of mature dendritic cells in vitro.
2007.05.18~2007.05.18, 第7回 シンポジウム 遺伝子・デリバリー研究会 2007, がんに対する免疫療法のための樹状細胞の増幅.
受賞
第28回日本消化器癌発生学会 研究奨励賞, 2017.11.

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