| 1. |
Ushijima Y, Nishie A, Fujita N, Kubo Y, Ishimatsu K, Ishigami K., Diagnostic accuracy of percutaneous core biopsy before cryoablation for small-sized renal cell carcinoma., Diagn Interv Radiol., 10.4274/dir.2022.221152., 2022.12. |
| 2. |
Fujita N, Ushijima Y, Itoyama M, Okamoto D, Ishimatsu K, Wada N, Takao S, Murayama R, Fujimori N, Nakata K, Nakamura M, Yamamoto T, Oda Y, Ishigami K., Extracellular volume fraction determined by dual-layer spectral detector CT: Possible role in predicting the efficacy of preoperative neoadjuvant chemotherapy in pancreatic ductal adenocarcinoma., Eur J Radiol., 10.1016/j.ejrad.2023.110756., 162, 2023.05. |
| 3. |
Takao S, Nishie A, Ushijima Y, Takayama Y, Morita K, Ishimatsu K, Koga Y, Mori Y, Akamine Y, Ishigami K., MR Prediction of Malignant Switch With the Cyst Fluid's T2 Value in Intraductal Papillary Mucinous Neoplasm of the Pancreas: A Preliminary Study., Anticancer Res., 10.21873/anticanres.15883., 42 , 8, 3895-3903, 2022.08. |
| 4. |
Takayama Y, Nishie A, Ishimatsu K, Ushijima Y, Fujita N, Kubo Y, Yoshizumi T, Kouhashi KI, Maehara J, Akamine Y, Ishigami K. , Diagnostic potential of T1ρ and T2 relaxations in assessing the severity of liver fibrosis and necro-inflammation., Magn Reson Imaging., 10.1016/j.mri.2022.01.002, 87, 104-112, 2022.01. |
| 5. |
Nishie A, Ushijima Y, Takayama Y, Fujita N, Kubo Y, Ishimatsu K, Tsurumaru D, Kohjima M, Ishigami K., Hemodynamic Alteration in the Liver in Acute Hepatitis: A Quantitative Evaluation Using Computed Tomographic Perfusion., In Vivo, 10.21873/invivo.12656., 2021.11. |
| 6. |
Takao S, Ushijima Y, Motomura Y, Sakamoto K, Hirakawa M, Nishie A, Mimori K, Yamashita Y, Tsutsumi T, Ishigami K., Radiology- and gene-based risk stratification in small renal cell carcinoma: A preliminary study., PLoS One, 10.1371/journal.pone.0256471, 2021.09, 目的：小径腎癌は一般的に予後良好であるが、高悪性度の一部は転移し予後不良となり、予後不良群を抽出するリスク層別化因子の同定が望まれている。本研究では、ゲノムプロファイリングとperfusion CT (pCT)やMRIの所見との関係性を評価し、有効なバイオマーカーとして利用できるイメージング因子の同定を試みた。
方法：2018/4～2019/3の間にpCT、MRIを施行した淡明細胞癌18例に対して生検組織からRNA sequenceを施行し発現量を求めた。本研究では腎癌におけるゲノムプロファィリングを元とした予後因子に細胞周期（CCP）スコアとclear cell type A/ clear cell type B (ccA/ccB) サブタイプを採用した。CCPスコアは腎癌における転移の独立予後因子、ccA/ccBサブタイプではccAに分類された症例はccBに対して予後が良好なことが判明している。
腫瘍の画像評価では、腫瘍径と脂肪・偽被膜の有無を評価し、また腫瘍の画像パラメータ（Ktrans・Kep・VE・VP・ADC）を測定した。これらのパラメータと腫瘍径腫瘍のザイズ、RNA発現との関連性を評価した。
結果：腫瘍径はKepと正の相関、VE, VP, ADC, 血管新生のRNA発現と負の相関を示した。CCPスコアはKep. KtransKtrans, Kepと負の相関を示した。ccAに分類された腫瘍ではMRIで偽被膜が観察しやすい傾向があった。
結論：腫瘍径は腫瘍の低灌流と関連があったが、ゲノムプロファイリングをもとにした予後因子との関連は見られなかった。KtransやKepといったパラメータや偽被膜といった腫瘍の特徴は遺伝子ベースのリスク層別化を可能にするかもしれない。. |
| 7. |
Yasuhiro Ushijima, Yoshiki Asayama, Akihiro Nishie, Yukihisa Takayama, Yuichiro Kubo, Keisuke Ishimatsu, Kousei Ishigami, Cryoablation for Secondary Renal Cell Carcinoma After Surgical Nephrectomy, Cardiovascular and Interventional Radiology
, 10.1007/s00270-020-02709-w, 44(3), 414-420, 2021.03. |
| 8. |
Ushijima Y, Asayama Y, Nishie A, Ishigami K, Takayama Y, Okamoto D, Fujita N, Morita K, Honda H., Safety and Efficacy of Embolization Using N-Butyl Cyanoacrylate via a Percutaneous Direct Approach for
Endoleaks after Abdominal/Thoracic Endovascular Aortic Repair, Interventional Radiology, 2020.03. |
| 9. |
Ushijima Y, Asayama Y, Nishie A, Tajima T, Yoshimitsu K, Hirakawa M, Ishigami K, Kakihara D, Okamoto D, Kotoh K, Honda H, Prognostic Factors of Computed Tomography Findings in Patients with Severe Acute Hepatic Failure Scheduled to Undergo Transcatheter Arterial Steroid Injection Therapy, Interventional Radiology, 2019.03. |
| 10. |
Ushijima Y, Tajima T, Nishie A, Asayama Y, Ishigami K, Hirakawa M, Kakihara D, Okamoto D, Honda H., Detecting hepatic nodules and identifying feeding arteries of hepatocellular carcinoma: efficacy of cone-beam computed tomography in transcatheter arterial chemoembolization, Hepatoma Res, 2016.01. |
| 11. |
Daichi Momosaka, Yasuhiro Ushijima, Akihiro Nishie, Asayama Yoshiki, Ishigami Kousei, Takayama yukihisa, Daisuke Okamoto, Nobuhiro Fujita, Hiroshi Honda, A Retroperitoneal Isolated Enteric Duplication Cyst Mimicking a Teratoma: A Case Report and Literature Review., Case Report in Radiology, 2016.12. |
| 12. |
Ushijima Y, Tajima T, Yoshimitsu K, Irie H, Nishie A, Hirakawa M, Ishigami K, Okamoto D, Kotoh K, Honda H, Radiological catheter placement for transcatheter arterial steroid injection therapy to treat severe acute hepatic failure: technical feasibility and efficacy., Acta Radiologica, 2012.03. |
| 13. |
Nishie A, Ushijima Y, Tajima T, Asayama Y, Ishigami K, Kakihara D, Nakayama T, Takayama Y, Okamoto D, Abe K, Obara M, Yoshimitsu K, Honda H.
, Quantitative analysis of liver function using superparamagnetic iron oxide- and Gd-EOB-DTPA-enhanced MRI: Comparison with Technetium-99m galactosyl serum albumin scintigraphy., Eur J Radiol., 2011.05. |
| 14. |
Matsumoto K, Ushijima Y, Tajima T, Nishie A, Hirakawa M, Ishigami K, Yamaji Y, Honda H., Recanalization of splenic artery aneurysm after transcatheter arterial embolization using N-butyl cyanoacrylate., Cardiovasc Intervent Radiol., 2010.02. |
| 15. |
Nishie A, Tajima T, Ishigami K, Ushijima Y, Okamoto D, Hirakawa M, Nishihara Y, Taketomi A, Hatakenaka M, Irie H, Yoshimitsu K, Honda H., Detection of hepatocellular carcinoma (HCC) using super paramagnetic iron oxide (SPIO)-enhanced MRI: Added value of diffusion-weighted imaging (DWI)., J Magn Reson Imaging., 2010.02. |
| 16. |
Ishigami K, Tajima T, Nishie A, Ushijima Y, Fujita N, Asayama Y, Kakihara D, Irie H, Ito T, Igarashi H, Nakamura M, Honda H., MRI findings of pancreatic lymphoma and autoimmune pancreatitis: a comparative study., Eur J Radiol., 2010.06. |
| 17. |
Yanaru-Fujisawa R, Matsumoto T, Ushijima Y, Esaki M, Hirahashi M, Gushima M, Yao T, Nakabeppu Y, Iida M., Genomic and functional analyses of MUTYH in Japanese patients with adenomatous polyposis., Clin Genet., 2008.06. |
| 18. |
Ushijima Y, Tominaga Y, Miura T, Tsuchimoto D, Sakumi K, Nakabeppu Y., A functional analysis of the DNA glycosylase activity of mouse MUTYH protein excising 2-hydroxyadenine opposite guanine in DNA., Nucleic Acids Res., 10.1093/nar/gki214, 33, 2, 672-682, 2005.01. |
| 19. |
Tominaga Y, Ushijima Y, Tsuchimoto D, Mishima M, Shirakawa M, Hirano S, Sakumi K, Nakabeppu Y., MUTYH prevents OGG1 or APEX1 from inappropriately processing its substrate or reaction product with its C-terminal domain., Nucleic Acids Res., 10.1093/nar/gkh642, 32, 10, 3198-3211, 2004.06. |
| 20. |
Ichinoe A, Behmanesh M, Tominaga Y, Ushijima Y, Hirano S, Sakai Y, Tsuchimoto D, Sakumi K, Wake N, Nakabeppu Y., Identification and characterization of two forms of mouse MUTYH proteins encoded by alternatively spliced transcripts., Nucleic Acids Res, 10.1093/nar/gkh214, 32, 2, 477-487, 2004.01. |
| 21. |
牛島泰宏、村田繁利、真武邦茂、角南俊哉、澤本博文, 直腸癌術後経過中に発症した肺類上皮血管内皮腫の１例, 臨床放射線, 2000.01. |
| 22. |
Hirano S, Tominaga Y, Ichinoe A, Ushijima Y, Tsuchimoto D, Sakumi K, Nakabeppu Y. , Mutator phenotype of MUTYH-null mouse embryonic stem cells.
, J Biol Chem, 10.1074/jbc.C300316200, 278, 40, 38121-38124, 2003.10. |
