| 1. |
S. Nakamura, T. Matsumoto, J. Umeno, S. Yanai, Y. Shono, H. Suekane, M. Hirahashi, T. Yao, M. Lida, Endoscopic features of intestinal follicular lymphoma: the value of double-balloon enteroscopy, ENDOSCOPY, 10.1055/s-2007-966223, Vol.39, pp.E26-E27, 2007.02. |
| 2. |
Kouichi Asano, Junji Umeno, Tomohiko Moriyama, Motohiro Esaki, Hideki Koga, Shotaro Nakamura, Toshiyuki Matsui, Takayuki Matsumoto, The Effect of HLA and Non-HLA Alleles on Susceptibility to Ulcerative Colitis, DIGESTIVE DISEASES AND SCIENCES, Vol.56, No.10, p.2769, 2011.10. |
| 3. |
Motohiro Esaki, Takayuki Matsumoto, Junji Umeno, Kouichi Asano, Tomohiko Moriyama, Shotaro Nakamura, Takanari Kitazono, Long-Term Effect of Infliximab Against Postoperative Recurrence of Mucosal Lesions in Patients With Crohn's Disease, GASTROENTEROLOGY, Vol.142, No.5, p.S352, 2012.05. |
| 4. |
Motohiro Esaki, Takayuki Matsumoto, Junji Umeno, Kouichi Asano, Tomohiko Moriyama, Shotaro Nakamura, Takanari Kitazono, Factors Affecting Postoperative Recurrence in Japanese Patients With Crohn's Disease in The Era of Biologic Therapy: Retrospective Single Center Study, INFLAMMATORY BOWEL DISEASES, Vol.18, pp.S65-S66, 2012.12. |
| 5. |
Kouichi Asano, Motohiro Esaki, Junji Umeno, Yuji Maehata, Tomohiko Moriyama, Shotaro Nakamura, Takanari Kitazono, Genetic Variants At FCGR2A and 13q12 Are Associated With Disease Couse in Ulcerative Colitis, GASTROENTEROLOGY, Vol.146, No.5, p.S878, 2014.05. |
| 6. |
H. Tanaka, N. Kamata, A. Yamada, K. Endo, T. Fujii, T. Yoshino, T. Sugaya, Y. Yokoyama, S. Bamba, J. Umeno, Y. Yanai, M. Ishii, T. Kawaguchi, S. Shinzaki, Y. Toya, T. Kobayashi, M. Nojima, T. Hibi, Mid-to long-term stability and associated prognostic factors of adalimumab treatment for 1 189 patients with Crohn's disease: a multicentre cohort study, JOURNAL OF CROHNS & COLITIS, Vol.10, p.S55, 2016.03. |
| 7. |
Satoko Yamaguchi, Shunichi Yanai, Shotaro Nakamura, Keisuke Kawasaki, Makoto Eizuka, Noriyuki Uesugi, Tamotsu Sugai, Junji Umeno, Motohiro Esaki, Takayuki Matsumoto, Immunohistochemistry differentiation between chronic enteropathy associated with SLCO2A1 and other inflammatory bowel diseases, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, Vol.31, p.123, 2016.11. |
| 8. |
Yoichi Kakuta, Yosuke Kawai, Takeo Naito, Atsushi Hirano, Junji Umeno, Keiichiro Hiramoto, Masatake Kuroha, Yoshitake Kanazawa, Tomoya Kimura, Katsuya Endo, Yoshitaka Kinouchi, Motohiro Esaki, Masao Nagasaki, Tooru Shimosegawa, POPULATION-OPTIMIZED SNP ARRAY REVEALS RAP1A AS A NOVEL CANDIDATE SUSCEPTIBILITY GENE FOR CROHN'S DISEASE IN JAPANESE INDIVIDUALS, GASTROENTEROLOGY, Vol.152, No.5, p.S78, 2017.04. |
| 9. |
Shunichi Yanai, Satoko Yamaguchi, Shotaro Nakamura, Keisuke Kawasaki, Makoto Eizuka, Noriyuki Uesugi, Tamotsu Sugai, Junji Umeno, Motohiro Esaki, Takayuki Matsumoto, Immunohistochemical Distinction of Chronic Enteropathy Associated with SLCO2A1 from Crohn's Disease, INFLAMMATORY BOWEL DISEASES, Vol.23, p.S63, 2017.02. |
| 10. |
Clinical Features of Chronic Enteropathy Associated with SLCO2A1 Gene (CEAS). |
| 11. |
Enteroscopic Diagnosis in Hemorrhagic Small Intestinal Diseases-Miscellaneous Diseases. |
| 12. |
Pathophysiology and clinical features of collagenous colitis. |
| 13. |
Clinical Features of Ischemic Enteritis. |
| 14. |
Genetic Background of Inflammatory Bowel Disease. |
| 15. |
Clinical Usefulness of Capsule Endoscopy in Patients with Multiple Small Intestinal Tumors. |
| 16. |
Clinicopathological and Endoscopic Features of Upper Gastrointestinal Lesions in Patients with Amyloidosis. |
| 17. |
Conventional Radiography for the Differential Diagnosis of Ulcerative Lesions of the Small Intestine. |
| 18. |
Radiographic Characteristics of Early Stage Ulcerative Colitis-Associated Neoplasia. |
| 19. |
GI Involvement in Vasculitis with Granuloma. |
| 20. |
Granulomatous Gastritis Caused by Mycobacterium Infection, Report of a Case. |
| 21. |
Conventional Radiography for the Differential Diagnosis of Small Bowel Disease with Stenosis. |
| 22. |
Gastrointestinal Skin Involvements in Collagen Disease and the Vasculitis. |
| 23. |
Mucocutaneous Manifestations of Gastrointestinal Polyposis Syndromes. |
| 24. |
Chronic Enteropathy Associated with the SLCO2A1 Gene Presenting as Digital Clubbing and Pachydermia, Report of Two Cases. |
| 25. |
Differential diagnosis of gastrointestinal polyposes based on gastric manifestations. |
| 26. |
Management of Duodenal Lesions in Patients with Familial Adenomatous Polyposis. |
| 27. |
Pathogenesis of nonspecific multiple ulcers in small intestine. |
| 28. |
Long-term Treatment of Chronic Enteropathy Associated with SLCO2A1 Gene (CEAS) Accompanied by Primary Hypertrophic Osteoarthropathy. |
| 29. |
Intestinal involvement in ANCA-associated vasculitis. |
| 30. |
Trisomy 8-positive Myelodysplastic Syndrome Associated with Intractable Intestinal Behcet’s Disease, Report of a Case. |
| 31. |
Radiographic Diagnosis of the Small Bowel Disease. |
| 32. |
Simple ulcer and intestinal lesions associated with trisomy 8: differential diagnoses of intestinal Behcet’s disease. |
| 33. |
Two Cases of Monomorphic Epitheliotropic Intestinal T-cell Lymphoma. |
| 34. |
Gastric Ulcer with IgG4-related Disease, Report of a Case. |
| 35. |
CLINICOPATHOLOGIC FEATURES OF CHRONIC NONSPECIFIC MULTIPLE ULCERS OF THE SMALL INTESTINE (CHRONIC ENTEROPATHY ASSOCIATED WITH SLCO2A1 GENE). |
| 36. |
Juvenile polyposis syndrome. |
| 37. |
Radiographic and Endoscopic Findings in Small-bowel Malignant Neoplasms. |
| 38. |
Collagenous colitis. |
| 39. |
Malignant Lymphoma of the Small Intestine, whose Initial Diagnosis was Obscure-A Clinicopathological Study with Special Reference to Radio-graphic, Macrosocpic and Histologic Features. |
| 40. |
Drug-induced Collagenous Colitis-Special Reference to the Endoscopic Features of Lansoprazole-associated Cases. |
| 41. |
DIAGNOSIS AND MANAGEMENT OF COLLAGENOUS COLITIS. |
| 42. |
Recent advances in genetic research of inflammatory bowel disease. |
| 43. |
Hiroki Tanaka, Noriko Kamata, Akihiro Yamada, Katsuya Endo, Toshimitsu Fujii, Takuya Yoshino, Takeshi Sugaya, Yoko Yokoyama, Shigeki Bamba, Junji Umeno, Yuka Yanai, Manabu Ishii, Takaaki Kawaguchi, Shinichiro Shinzaki, Yosuke Toya, Taku Kobayashi, Masanori Nojima, Toshifumi Hibi, Mid- to Long-Term Stability and Associated Prognostic Factors of Adalimumab Treatment for 1189 Patients With Crohn's Disease: A Multicenter Cohort Study, GASTROENTEROLOGY, 10.1016/S0016-5085(16)32728-7, Vol.150, No.4, p.S806, 2016.04. |
| 44. |
Colitis associated with anticancer/molecular-targeted drug. |
| 45. |
Profile Views of Early Colorectal Cancers during Barium Enema. |
| 46. |
Nakanishi T, Nakamura Y, Umeno J, Recent advances in studies of SLCO2A1 as a key regulator of the delivery of prostaglandins to their sites of action., Pharmacology & Therapeutics, 10.1016/j.pharmthera.2021.107803, Vol.223, p.107803, 2021.01, Solute carrier organic anion transporter family member 2A1 (SLCO2A1, also known as PGT, OATP2A1, PHOAR2, or SLC21A2) is a plasma membrane transporter consisting of 12 transmembrane domains. It is ubiquitously expressed in tissues, and mediates the membrane transport of prostaglandins (PGs, mainly PGE2, PGF2α, PGD2) and thromboxanes (e.g., TxB2). SLCO2A1-mediated transport is electrogenic and is facilitated by an outwardly directed gradient of lactate. PGs imported by SLCO2A1 are rapidly oxidized by cytoplasmic 15-hydroxyprostaglandin dehydrogenase (15-PGDH, encoded by HPGD). Accumulated evidence suggests that SLCO2A1 plays critical roles in many physiological processes in mammals, and it is considered a potential pharmacological target for diabetic foot ulcer treatment, antipyresis, and non-hormonal contraception. Furthermore, whole-exome analyses suggest that recessive inheritance of SLCO2A1 mutations is associated with two refractory diseases, primary hypertrophic osteoarthropathy (PHO) and chronic enteropathy associated with SLCO2A1 (CEAS). Intriguingly, SLCO2A1 is also a key component of the Maxi-Cl channel, which regulates fluxes of inorganic and organic anions, including ATP. Further study of the bimodal function of SLCO2A1 as a transporter and ion channel is expected to throw new light on the complex pathology of human diseases. Here, we review and summarize recent information on the molecular functions of SLCO2A1, and we discuss its pathophysiological significance.. |
| 47. |
Clinical Practice and Usefulness of Small Bowel Radiography. |
| 48. |
Diagnosis of Gastrointestinal Polyposis Syndromes. |
| 49. |
Clinical features of chronic enteropathy associated with SLCO2A1 gene (CEAS). |
| 50. |
IBD unclassified (IBDU)/Indeterminate colitis (IC). |
| 51. |
Non-neoplastic Disease of the Small Intestine-Chronic Enteropathy Associated with the SLCO2A1 Gene (CEAS). |
| 52. |
Gastrointestinal Manifestations in Systemic Lupus Erythematosus. |
| 53. |
motohiro esaki, Umeno Junji, Takanari Kitazono, Clinicopathologic features of chronic nonspecific multiple ulcers of the small intestine., Clinical journal of gastroenterology, 10.1007/s12328-015-0559-x, Vol.8, No.2, pp.57-62, 2015.04, Chronic nonspecific multiple ulcers of the small intestine is a rare but distinct clinical condition, characterized by multiple small intestinal ulcers of nonspecific histology and chronic, persistent gastrointestinal bleeding without nonsteroidal anti-inflammatory drug use. However, because of the term "nonspecific" in its nomenclature, some gastroenterologists have misinterpreted the disease as the condition with small intestinal ulcers caused by undetermined etiologies without considering clinical features. Such misinterpretation has led to the heterogeneity of clinicopathologic features of the disease, as well as to ambiguity regarding a possible genetic contribution. It thus seems necessary to recognize the clinical entity of the disease precisely to avoid misinterpretation. In this review, we describe the clinicopathologic features, differential diagnosis, and the possibility of a genetic contribution to the disease.. |
| 54. |
Umeno Junji, Motohiro Esaki, Takayuki Matsumoto, lansoprazole consumption is more common in Japanese patients with collagenous colitis., 2013.07. |
| 55. |
Endoscopic Diagnosis of Nontumorous Lesions of the Small Intestine. |
