Kyushu University Academic Staff Educational and Research Activities Database
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Naoya Shindo Last modified date:2019.06.28

Assistant Professor / 創薬育薬研究施設統括室
Department of Pharmaceutical Health Care and Sciences
Faculty of Pharmaceutical Sciences




E-Mail
Phone
092-642-6600
Fax
092-642-6601
Academic Degree
Ph.D. in Pharmaceutical Sciences
Country of degree conferring institution (Overseas)
No
Field of Specialization
Medicinal chemistry, Synthetic organic chemistry
Research
Research Interests
  • Development of novel reactive warhead for highly target selective covalent inhibitors
    keyword : covalent drug, medicinal chemistry, TCI
    2013.06~2018.06.
Academic Activities
Papers
1. Naoya Shindo, Hirokazu Fuchida, Mami Sato, Kosuke Watari, Tomohiro Shibata, Keiko Kuwata, Chizuru Miura, Kei Okamoto, Yuji Hatsuyama, Keisuke Tokunaga, Seiichi Sakamoto, Satoshi Morimoto, Yoshito Abe, Mitsunori Shiroishi, Jose M. M. Caaveiro, Tadashi Ueda, Tomonori Tamura, Naoya Matsunaga, Takaharu Nakao, Satoru Koyanagi, Shigehiro Ohdo, Yasuchika Yamaguchi, Itaru Hamachi, Mayumi Ono, Akio Ojida, Selective and reversible modification of kinase cysteines with chlorofluoroacetamides, Nature Chemical Biology, https://doi.org/10.1038/s41589-018-0204-3, 15, 3, 250-258, 2019.01.
2. Hirokazu Fuchida, Shigekazu Tabata, Naoya Shindo, Ippei Takashima, Qiao Leng, Yuji Hatsuyama, Itaru Hamachi, Akio Ojida, Design of Coordination Interaction of Zn(II) Complex with Oligo-Aspartate Peptide to Afford a High-Affinity Tag-Probe Pair, Bulletin of the Chemical Society of Japan, 10.1246/bcsj.20150037, 88, 784-791, 2015, 88, 784, 2015.03.
3. Ikuko Takahira, Hirakazu Fuchida, Shigekazu Tabata, Naoya Shindo, Shohei Uchinomiya, Itaru Hamachi, Akio Ojida, Design of a binuclear Ni(II)-iminodiacetic acid (IDA) complex for selective recognition and covalent labeling of His-tag fused proteins, Bioorganic & Medicinal Chemistry Letters, 10.1016/j.bmcl.2014.04.096, 24, 2855-2858, 2014, 24, 2855, 2014.03.
Presentations
1. Naoya Shindo, Selective and Reversible Covalent Modification of Non-Catalytic Cysteines with Weakly Reactive α-Chlorofluoroacetamides, KU-NTU Joint International Symposium on Pharmaceutical Sciences, 2018.03.