Kyushu University Academic Staff Educational and Research Activities Database
List of Reports
Tomohiro Yamada Last modified date:2019.07.11

Associate Professor / Division of Maxillofacial Diagnostic and Surgical Sciences / Department of Dental Science / Faculty of Dental Science

1. Naoya Kitamura, Tomohiro Yamada, Complete remission of Merkel cell carcinoma on the upper lip treated with radiation monotherapy and a literature review of Japanese cases., World Journal of Surgical Oncology, 2015.04.
2. Tomohiro Yamada, Mayu Takahashi, Manabu Matsumoto, Makoto toi, Seiji Ohno, Naoya Kitamura, Eri Sasabe, Tetsuya Yamamoto, Mucinous Cystadenoma in the Upper Lip: Report of Two Cases, Int J Surg Pathol, 2013.07, Mucinous cystadenoma of the salivary gland is a very rare disease, and only a few cases have been reported. We report here 2 cases of mucinous cystadenoma in the upper lip. The first case was a 57-year-old man and the second was a 42-year-old woman. The tumors were painless nodules with a smooth-surfaced mucosa, and surgical excisions were performed. Histologically, the tumors were surrounded by a fibrous capsule and were composed of multiple cysts lined with columnar epithelial cells. The tumor cells contain mucous substances that reacted with periodic acid-Schiff base and Alcian blue. Immunohistochemical staining revealed that the tumor cells expressed cytokeratin (AE1/3 and CK7), but their immunoreactivity with MIB-1 (Ki-67) was less than 3%. They had negative immunoreactivity for neuroectoderm markers, S-100 protein, and myoepithelial markers, p63, α-smooth muscle actin, and calponin, except for the accompanying myoepithelial-like cells. No recurrences were noted after surgery at 7 years and 1 year, respectively..