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Kazufumi Kunimura Last modified date：2024.04.08

Assistant Professor / Division of Immunogenetics
Department of Immunobiology and Neuroscience
Medical Institute of Bioregulation




Homepage
https://kyushu-u.elsevierpure.com/en/persons/kazufumi-kunimura
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https://researchmap.jp/-kunimura-
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http://www.bioreg.kyushu-u.ac.jp/iden/
免疫遺伝学分野 紹介HP .
Phone
092-642-6828
Fax
092-642-6829
Academic Degree
Ph.D., M.D.
Field of Specialization
Immunology, Cell biology
Research
Research Interests
  • Fetomaternal immune cross-talk
    keyword : Pregnancy, Allergy
    2019.04.
  • Development of novel drugs for atopic dermatitis
    keyword : Atopic dermatitis, IL-31, Academia drug discovery
    2020.04.
Academic Activities
Reports
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1. Kazufumi Kunimura, Yoshinori Fukui, The molecular basis for IL-31 production and IL-31-mediated itch transmission: from biology to drug development, International Immunology, 10.1093/intimm/dxab065, 2021.09.
2. Kazufumi Kunimura, Takehito Uruno, Yoshinori Fukui, DOCK family proteins: key players in immune surveillance mechanisms., International immunology, 10.1093/intimm/dxz067, Vol.32, No.1, pp.5-15, 2020.01.
Papers
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1. Kenji Morino*, Kazufumi Kunimura*, Yuki Sugiura, Yoshihiro Izumi, Keisuke Matsubara, Sayaka Akiyoshi, Rei Maeda, Kenichiro Hirotani, Daiji Sakata, Seiya Mizuno, Satoru Takahashi, Takeshi Bamba, Takehito Uruno, Yoshinori Fukui, Cholesterol sulfate limits neutrophil recruitment and gut inflammation during mucosal injury, Frontiers in Immunology, 10.3389/fimmu.2023.1131146, 2023.03.
2. Kazufumi Kunimura, Sayaka Akiyoshi, Takehito Uruno, Keisuke Matsubara, Daiji Sakata, Kenji Morino, Kenichiro Hirotani, Yoshinori Fukui, DOCK2 regulates MRGPRX2/B2-mediated mast cell degranulation and drug-induced anaphylaxis, The Journal of Allergy and Clinical Immunology, 10.1016/j.jaci.2023.01.029, 2023.02.
3. Kazufumi Kunimura, Kazuhiko Yamamura, Takeshi Nakahara, Makiko Kido-Nakahara, Takehito Uruno, Yoshinori Fukui, Identification of a functional DOCK8 gene polymorphism associated with atopic dermatitis, Allergy, 10.1111/all.15429, 2022.07.
4. Keisuke Matsubara*, Kazufumi Kunimura*, Nana Yamane, Ryosuke Aihara, Tetsuya Sakurai, Daiji Sakata, Takehito Uruno, Yoshinori Fukui, DOCK8 deficiency causes a skewing to type 2 immunity in the gut with expansion of group 2 innate lymphoid cells, Biochemical and Biophysical Research Communications, 10.1016/j.bbrc.2021.04.094, 559, 135-140, 2021.06.
5. Ryosuke Aihara*, Kazufumi Kunimura*, Mayuki Watanabe, Takehito Uruno, Nana Yamane, Tetsuya Sakurai, Daiji Sakata, Fusanori Nishimura, Yoshinori Fukui, DOCK8 controls survival of group 3 innate lymphoid cells in the gut through Cdc42 activation., International Immunology, 10.1093/intimm/dxaa066, 33, 3, 149-160, 2020.09.
6. Kazufumi Kunimura, Daiji Sakata, Xin Tun, Takehito Uruno, Miho Ushijima, Tomoya Katakai, Akira Shiraishi, Ryosuke Aihara, Yasuhisa Kamikaseda, Keisuke Matsubara, Hirokazu Kanegane, Shinichiro Sawa, Gérard Eberl, Shouichi Ohga, Yasunobu Yoshikai, Yoshinori Fukui, S100A4 Protein Is Essential for the Development of Mature Microfold Cells in Peyer's Patches., Cell reports, 10.1016/j.celrep.2019.10.091, 29, 9, 2823-2834, 2019.11.
Presentations
 Show All Presentations >>
1. 國村 和史, 福井 宣規, アトピー性皮膚炎に関わる機能的なDOCK8遺伝子多型の同定, 第52回日本免疫学会学術集会, 2024.01.
2. Novel mechanism of inflammation resolution by intestinal metabolites with the ability to suppress immune cell migration.
3. 國村 和史, DOCK2は肥満細胞のMRGPRX2/B2介在性脱顆粒と薬剤誘発性アナフィラキシーを制御する, 第18回生命医科学研究所ネットワーク国際シンポジウム, 2023.10.
4. 國村 和史, 宇留野 武人, 福井 宣規, DOCK2/DOCK8分子を介した多彩な免疫制御メカニズム, 第96回日本生化学会大会, 2023.10.
5. 國村 和史, 薬剤性アナフィラキシーに関わるMRGPRB2/X2受容体のシグナル経路の解明, 第51回日本免疫学会学術集会, 2022.12.
Membership in Academic Society
  • Japan Society for DOHaD (Developmental Origins of Health and Disease)
  • Japanese Society of Allergology
  • Japanese Society for Immunology
Awards
  • Intelligence of the Year 2014


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