| Rie Sonoi | Last modified date：2024.03.27 |
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Homepage
https://kyushu-u.elsevierpure.com/en/persons/rie-sonoi
Reseacher Profiling Tool Kyushu University Pure
Phone
092-802-2805
Country of degree conferring institution (Overseas)
No
Field of Specialization
Biochemical engineering
ORCID(Open Researcher and Contributor ID)
https://orcid.org/0000-0002-8597-8942
Total Priod of education and research career in the foreign country
00years00months
Outline Activities
Establishment of non-invasive and quantitative evaluation methods based on cell characteristics and behaviors
Research
Research Interests
Membership in Academic Society
- １．Study on quantitative evaluation and regulation of the maturation through the migratory behaviors of human retinal pigment epithelial cells in confluent state (2011-2017).
２．Study on the development of process and quality control technology for inducing differentiation of human iPS cells into retinal pigment epithelial cells for use in the transplantation (2014-2015).
３．Study on the development of quantitative and non-invasive evaluation methods to understand drug toxicity in HepaRG aggregates using Optical Coherence Tomography (OCT) (2018-2021).
４．Study on establishment of quantitative and non-invasive evaluation methods to understand drug toxicity based on the change in the bile canaliculi behaviors of Hepatocytes (2018-2022).
keyword : confluent state, epithelial cells, non-invasive evaluation, image analysis, regenerative medicine, drug discovery
2023.01. - A novel strategy to facilitate uniform epithelial cell maturation using liquid–liquid interfaces
keyword : liquid-liquid interfaces，epithelial cell, uniform maturation, tight junction, cell behavior
2023.04～2025.03.
Papers
| 1. | Sonoi, R. and Hagihara Y., Quantitative understanding of HepaRG cells during drug‐induced intrahepatic cholestasis through changes in bile canaliculi dynamics, Pharmacology Research & Perspectives, 10.1002/prp2.960, 2022.05.  |
| 2. | Sonoi, R. and Hagihara Y., Tight junction stabilization prevents HepaRG cell death in drug-induced intrahepatic cholestasis, Biology Open, 10.1242/bio.058606, 2021.06. |
| 3. | Sonoi, R., Yamakawa, T., Nakatani, N., Kokubo, M., and Hagihara, Y., Noninvasive Evaluation of HepaRG Aggregates during Drug‐Induced Intrahepatic Cholestasis Using Optical Coherence Tomography, Advanced Biology, 10.1002/adbi.202000198, 5, 2, 2021.02. |
| 4. | Sonoi, R., and Hagihara, Y., Switching of cell fate through the regulation of cell growth during drug-induced intrahepatic cholestasis, Journal of Bioscience and Bioengineering, 10.1016/j.jbiosc.2020.08.004, 130, 6, 659-665, 2020.12. |
| 5. | Sonoi, R., Kim, M.H., Yamada, K., and Kino-oka, M., Phenotypic heterogeneity of human retinal pigment epithelial cells in passaged cell populations, Journal of bioscience and bioengineering, 10.1016/j.jbiosc.2017.03.008, 124, 2, 227-233, 2017.08. |
| 6. | Sonoi, R., Kim, M.H., and Kino-oka, M., Facilitation of uniform maturation of human retinal pigment epithelial cells through collective movement in culture, Journal of bioscience and bioengineering, 10.1016/j.jbiosc.2015.05.019, 121, 2, 220-226, 2016.02. |
| 7. | Sonoi, R., Kim, M.H., and Kino-oka, M., Locational heterogeneity of maturation by changes in migratory behaviors of human retinal pigment epithelial cells in culture, Journal of bioscience and bioengineering, 10.1016/j.jbiosc.2014.05.025, 119, 1, 107-112, 2015.01. |
| 8. | Kim, M.H., Sonoi, R., Yamada, K., Inamori, M., and Kino-oka, M., Analysis of locality of early-stage maturation in confluent state of human retinal pigment epithelial cells, Journal of bioscience and bioengineering, 10.1016/j.jbiosc.2012.02.009, 113, 6, 778-781, 2012.06. |
Presentations
- The society for biotechnology
- The japanese society for regenerative medicine
- Parenteral Drug Association
- The Japanese Society for Biomaterials
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