https://kyushu-u.elsevierpure.com/en/persons/shozo-jinno
　Reseacher Profiling Tool　Kyushu University Pure

092-642-6051

092-642-6202

MD, PhD

No

Neuroscience

0000-0002-7596-8118

01years06months

(1) We create various mouse models for psychiatric disorders using C57BL/6J mice in our lab, such as, depression, schizophrenia, PTSD, cocaine addiction, and cancer-related cognitive impairment, etc.
(2) We analyze behavioral phenotypes of model models for psychiatric disorders are analyzed by the test battery, such as open-field test, T-maze, Y-maze, elevated plus maze, fear conditioning, operant conditioning, CPP, FST, and PPI, etc.
(3) We analyze synapses, neurons, and glial cells in the neuronal circuits of the hippocampus obtained from various model mice to understand the pathophysiology of psychiatric disorders. To this end, we use anatomical, pharmacological, and molecular biological methods. We also used the DREADD technologies with several Cre transgenic mouse lines.
(4) We analyze synapses, neurons, and glial cells in the neuronal circuits of the hippocampus of normal mice using anatomical and electrophysiological methods to understand the operating principles of the brain.
(5) Multidisciplinary analysis of the extracellular matrix in the central nervous system by using anatomical and electrophysiological techniques.
(6) Education of undergraduate students via lecture and practical course of neuroanatomy and gross anatomy.

Research Interests

• Using behavioral pharmacology, we analyze the hippocampus of the mouse models for depression, schizophrenia, PTSD, cancer-related cognitive impairment.
  keyword : depression, schizophrenia, epilepsy, aging, hippocampus
  2006.01Anatomical and electrophysiological evaluation of the plasticity hypothesis for psychiatric disorders.
• Anatomical analysis of adult neurogenesis in the hippocampus
  keyword : hippocampus, neurogenesis, granule cell, neural stem cell
  2009.04～2016.03I have performed electrophysiological analysis of hippocampal mossy cells, and found those in the ventral hilus exhibited rythmic bursting activity, which was brought by persisten sodium channels..
• Multidisciplinary analysis of long-range GABAergic projection systems in neural networks
  keyword : projection neuron, GABA, hippocampus, medial septum
  1998.04I am now engaged in multidisciplinary analysis of projection pathway of central nervous system by using anatomical and electrophysiological techniques to know the principle of neuron network system of the brain..
• Stereological and point process analyses of various neurons and glias in the central nervous system
  keyword : neuron, glia, stereology, quantitative analysis, point process analysis
  1996.041) I have estimated the numerical densities of 8 major subpopulations of GABAergic nonprincipal neurons in the mouse hippocampus using the optical disector method, and revealed their dorsoventral differences. 2) I have estimated the numerical densities and 3D distribution patterns of microglia in the mouse hippocampus. .
• Regulation of plasticity by perineuronal nets
  keyword : extracellular matrix, sugar chain, neuronal plasticity
  2011.11.
• Exploring the mechanism of action of plant-derived estrogen analogues on brain function
  keyword : plant-derived estrogen analogues, hippocampus, neuron, glia
  2017.04.

Academic Activities
Membership in Academic Society

• Society for Neuroscience

Educational Activities
Other Educational Activities

• 2015.01.
• 2014.01.
• 2013.01.