| 1. |
Yuri Nakamura, Laura Gaetano, Takuya Matsushita, Altermatt Anna, Till Sprenger, Ernst Wilhelm Radue, Lens Wuerfel, Lorena Bauer, Michael Amann, Koji Shinoda, Noriko Isobe, Ryo Yamasaki, Takahiko Saida, Ludwig Kappos, Jun-ichi Kira, A Comparison of Brain MRI Features between Asian and Caucasian Patients with Multiple Sclerosis, ANNALS OF NEUROLOGY, Vol.84, p.S106, 2018.10. |
| 2. |
Noriko Kuroki, Yasumasa Ohyagi, Yuji Kawano, Takashi Yoshiura, Takayuki Taniwaki, Jun-ichi Kira, Acute onset facial numbness Left idiopathic trigeminal sensory neuropathy, JOURNAL OF CLINICAL NEUROSCIENCE, 10.1016/j.jocn.2007.08.016, Vol.15, No.9, pp.1049-+, 2008.09. |
| 3. |
K. Masaki, T. Matsushita, N. Isobe, H. Une, T. Ishizu, Y. Kawano, J. I. Kira, Measurement of anti-aquaporin-4 antibody by a new flow cytometric assay and an enzyme-linked immunosorbent assay in comparison to a cell-based immunofluorescence assay, MULTIPLE SCLEROSIS, Vol.15, No.9, p.S37, 2009.09. |
| 4. |
H. Doi, T. Matsushita, N. Isobe, T. Matsuoka, M. Minohara, H. Ochi, J. Kira, Hypercomplementemia at relapse in patients with anti-aquaporin-4 antibody, MULTIPLE SCLEROSIS, Vol.15, No.1, p.146, 2009.01. |
| 5. |
N. Isobe, T. Matsushita, R. Yamasaki, S. Ramagopalan, Y. Kawano, Y. Nishimura, G. Ebers, J. I. Kira, Epistatic interactions at HLA-DRB1 in Japanese patients with multiple sclerosis, MULTIPLE SCLEROSIS, Vol.15, No.9, p.S184, 2009.09. |
| 6. |
N. Isobe, T. Matsushita, R. Yamasaki, S. V. Ramagopalan, Y. Kawano, Y. Nishimura, G. C. Ebers, J. Kira, The influence of HLA-DRB1 alleles on the susceptibility and resistance to multiple sclerosis with respect to the criteria of neuromyelitis optica, MULTIPLE SCLEROSIS, Vol.16, No.2, p.270, 2010.02. |
| 7. |
K. Masaki, T. Matsuoka, S. Suzuki, X. Wu, K. Zhang, T. Yonekawa, N. Isobe, A. Ordinario, T. Tabira, T. Iwaki, T. Matsushita, J. Kira, Extensive aquaporin 4 (AQP4) loss in Balo's concentric sclerosis in the absence of anti-AQP4 antibody, MULTIPLE SCLEROSIS, Vol.16, No.10, p.1288, 2010.10. |
| 8. |
H. Doi, S. Y. Song, T. Matsushita, N. Isobe, K. Masaki, J. Kira, Cytokine and T helper cell profiles in multiple sclerosis, MULTIPLE SCLEROSIS, Vol.16, No.10, p.1278, 2010.10. |
| 9. |
T. Yonekawa, K. Masaki, N. Isobe, S. Yoshimura, T. Matsushita, J. Kira, Reappraisal of longitudinally extensive spinal cord lesions by 3-Tesla MRI in anti-AQP4 antibody-seropositive and-seronegative NMO and MS patients, MULTIPLE SCLEROSIS JOURNAL, Vol.17, p.S378, 2011.10. |
| 10. |
Tomomi Yonekawa, Noriko Isobe, Takuya Matsushita, Yuji Kawano, Katsuhisa Masaki, Satoshi Yoshimura, Shu Chen, Bernard R. Smith, Jadwiga Furmaniak, Jun-ichi Kira, Quantitative Assays for Anti-Aquaporin 4 Antibodies (AQP4Abs) in Neuromyelitis Optica (NMO), NEUROLOGY, Vol.76, No.9, p.A537, 2011.03. |
| 11. |
S. Yoshimura, T. Matsushita, N. Isobe, T. Yonekawa, K. Masaki, J. -I. Kira, Interaction of the IL-7RA polymorphism rs6897932 and HLA-DRB1*0405 in Japanese multiple sclerosis patients, MULTIPLE SCLEROSIS JOURNAL, Vol.17, pp.S332-S333, 2011.10. |
| 12. |
T. Matsushita, T. Tateishi, T. Yonekawa, N. Isobe, J. -I. Kira, Increased CSF IL-17A, IL-6, CXCL8 and CXCL10 in patients with neuromyelitis optica at relapse and their clinical relevance, MULTIPLE SCLEROSIS JOURNAL, Vol.17, pp.S23-S24, 2011.10. |
| 13. |
Noriko Isobe, Tomomi Yonekawa, Takuya Matsushita, Yuji Kawano, Katsuhisa Masaki, Satoshi Yoshimura, Jun-ichi Kira, Distinct Features of Neuromyelitis Optica According to Anti-Aquaporin-4 Antibody IgG Subclass, ANNALS OF NEUROLOGY, Vol.70, p.S67, 2011.10. |
| 14. |
S. Yoshimura, T. Matsushita, N. Isobe, T. Yonekawa, K. Masaki, J-I. Kira, Common and distinct associations of HLA-DRB1 and-DPB1 alleles with anti-AQP4 antibody-seropositive NMO/NMOSD, -seronegative NMO/NMOSD, and non-NMO/NMOSD MS in Japanese, MULTIPLE SCLEROSIS JOURNAL, Vol.17, pp.S110-S111, 2011.10. |
| 15. |
Katsuhisa Masaki, Takeshi Matsuoka, Satoshi O. Suzuki, Tomomi Yonekawa, Noriko Isobe, Takeshi Tabira, Toru Iwaki, Xiaomu Wu, Takuya Matsushita, Jun-ichi Kira, Anti-AQP4 Antibody-Independent Astrocytopathy with Extensive Connexin Loss in Balo's Concentric Sclerosis and Allied Conditions, NEUROLOGY, Vol.76, No.9, p.A537, 2011.03. |
| 16. |
S. Yoshimura, N. Isobe, L. Fang, T. Matsushita, T. Yonekawa, K. Masaki, J. Kira, The IL-7RA Polymorphism rs6897932 only confers MS Susceptibility in Japanese when it interacts with HLA-DRB1*0405, MULTIPLE SCLEROSIS JOURNAL, Vol.18, No.4, p.523, 2012.04. |
| 17. |
N. Isobe, J. Kira, Genetic Background for Recent Increase of MS in Japanese, MULTIPLE SCLEROSIS JOURNAL, Vol.18, No.4, p.517, 2012.04. |
| 18. |
S. Sato, N. Isobe, S. Yoshimura, Y. Kanamori, K. Masaki, T. Matsushita, J-I. Kira, Distinct HLA polymorphisms among atopic myelitis, multiple sclerosis and neuromyelitis optica patients in Japan, MULTIPLE SCLEROSIS JOURNAL, Vol.18, p.65, 2012.10. |
| 19. |
N. Isobe, S. Yoshimura, T. Matsushita, T. Yonekawa, K. Masaki, J. Kira, Common Protective and Distinct Susceptibility HLA Class II Alleles in Neuromyelitis Optica and Multiple Sclerosis in Japanese According to Anti-AQP4 Antibody Status, MULTIPLE SCLEROSIS JOURNAL, Vol.18, No.4, p.524, 2012.04. |
| 20. |
S. Yoshimura, N. Isobe, T. Matsushita, T. Yonekawa, K. Masaki, J. Kira, An Increase in Japanese Multiple Sclerosis Patients with the Susceptibility Allele HLA-DRB1*0405 showing an Early Onset, Benign Course, MULTIPLE SCLEROSIS JOURNAL, Vol.18, No.4, p.523, 2012.04. |
| 21. |
N. Isobe, J. Huang, S. Yoshimura, T. Matsushita, T. Yonekawa, J. P. McElroy, S. L. Hauser, J. R. Oksenberg, J. Kira, A NOTCH4 Missense Mutation Contributes to Resistance to Multiple Sclerosis in Japanese, MULTIPLE SCLEROSIS JOURNAL, Vol.18, No.4, pp.523-524, 2012.04. |
| 22. |
Tomomi Yonekawa, Katsuhisa Masaki, Noriko Isobe, Satoshi Yoshimura, Takuya Matsushita, Jun-ichi Kira, Reappraisal of longitudinally extensive spinal cord lesions by 3 tesla MRI in anti-AQP4 antibody-seropositive and -seronegative NMO and MS patients, MULTIPLE SCLEROSIS JOURNAL, Vol.19, No.5, p.665, 2013.04. |
| 23. |
Yuji Kanamori, Noriko Isobe, Tomomi Yonekawa, Takuya Matsushita, Hiroshi Shigeto, Nobutoshi Kawamura, Ryo Yamasaki, Hiroyuki Murai, Shozo Tobimatsu, Jun-Ichi Kira, Multimodality evoked potentials for discrimination of atopic myelitis and multiple sclerosis, Clinical and Experimental Neuroimmunology, 10.1111/cen3.12018, Vol.4, No.1, pp.29-35, 2013.06, Objectives: To clarify the differences in multimodality evoked potential findings between patients with atopic myelitis (AM) and those with multiple sclerosis (MS). Methods: A retrospective chart review of 70 consecutive AM patients and 93 MS patients was carried out. All patients were negative for serum antiaquaporin- 4 antibody. Visual- (VEP), somatosensory- (SEP) and motor-evoked potentials (MEP) recorded at first examination, and magnetic resonance imaging (MRI) findings from the first examination were compared between AM and MS patients. Results: Compared with MS patients, AM patients showed male preponderance, lower the Expanded Disability Status Scale scores and less frequent spinal cord MRI lesions. Visual impairment and muscle weakness were also less severe in AM patients. Frequencies of abnormal VEP and prolonged central conduction time on lower limb MEP were significantly lower in AM patients than in MS patients (AM vs MS: 9.5% vs 55.6%, and 28.2% vs 54.4%, respectively), whereas frequencies of peripheral nerve involvement in upper and lower limb MEP and upper limb SEP were significantly higher in AM than in MS patients (AM vs MS: 12.8% vs 2.9%, 17.9% vs 2.9% and 33.3% vs 4.4%, respectively). When patients whose EP were examined within 5 years of disease onset were compared, lower frequencies of abnormal VEP and higher peripheral nerve involvement detected by MEP and SEP were observed in AM patients. Conclusions: AM patients have distinct physiological features compared with MS patients, even at the first examination of evoked potentials, which might suggest distinct immunological mechanisms between the two conditions. Multimodality evoked potentials might contribute to the early discrimination of these two disorders. © 2013 Japanese Society for Neuroimmunology.. |
| 24. |
Satoshi Yoshimura, Tomomi Yonekawa, Noriko Isobe, Takuya Matsushita, Jun-Ichi Kira, Bacterial infectious burden and prevalence of idiopathic central nervous system demyelinating diseases in Japanese, Clinical and Experimental Neuroimmunology, 10.1111/cen3.12047, Vol.4, No.3, pp.351-352, 2013.12. |
| 25. |
G. Ainiding, Y. Kawano, S. Sato, N. Isobe, T. Matsushita, S. Yoshimura, T. Yonekawa, R. Yamasaki, J. Kira, Interleukin 2 Receptor Alpha Chain Gene Polymorphisms and Risk of Multiple Sclerosis and Neuromyelitis Optica, MULTIPLE SCLEROSIS JOURNAL, Vol.20, No.7, p.923, 2014.06. |
| 26. |
Shinya Sato, Ken Yamamoto, Takuya Matsushita, Noriko Isobe, Yuji Kawano, Kyoko Iinuma, Tomomi Yonekawa, Katsuhisa Masaki, Satoshi Yoshimura, Ryo Yamasaki, Junichi Kira, Deletion-Type Copy Number Variations at T Cell Receptor Genes Confer Susceptibility to Multiple Sclerosis and Neuromyelitis Optica, ANNALS OF NEUROLOGY, Vol.76, pp.S110-S111, 2014.10. |
| 27. |
Yi Wen Cui, Yuji Kawano, Nan Shi, Katsuhisa Masaki, Noriko Isobe, Tomomi Yonekawa, Takuya Matsushita, Takahisa Tateishi, Ryo Yamasaki, Jun-ichi Kira, Cytokine Receptor Expression in Monocyte Subsets in Multiple Sclerosis, Neuromyelitis Optica, and Amyotrophic Lateral Sclerosis, MULTIPLE SCLEROSIS JOURNAL, Vol.20, No.7, p.944, 2014.06. |
| 28. |
Shinya Sato, Ken Yamamoto, Takuya Matsushita, Noriko Isobe, Yuji Kawano, Kyoko Iinuma, Tomomi Yonekawa, Katsuhisa Masaki, Satoshi Yoshimura, Ryo Yamasaki, Jun-ichi Kira, Copy number variations in T cell receptor loci are associated with susceptibility to multiple sclerosis and neuromyelitis optica, JOURNAL OF NEUROIMMUNOLOGY, 10.1016/j.jneuroim.2014.08.140, Vol.275, No.1-2, p.53, 2014.10. |
| 29. |
S. Sato, K. Yamamoto, T. Matsushita, N. Isobe, Y. Kawano, K. Iinuma, T. Yonekawa, K. Masaki, S. Yoshimura, R. Yamasaki, J-I Kira, A genome-wide copy number variation study identified T-cell receptor as a susceptibility gene for multiple sclerosis and neuromyelitis optica, MULTIPLE SCLEROSIS JOURNAL, Vol.20, pp.251-252, 2014.09. |
| 30. |
Y. Nakamura, T. Matsushita, S. Sato, M. Niino, T. Fukazawa, S. Yoshimura, S. Hisahara, N. Isobe, S. Shimohama, K. Yoshida, H. Houzen, Y. Miyazaki, S. Kikuchi, J. Kira, Multiple Sclerosis Susceptibility/Resistance and Clinical Manifestations are Determined by HLA-DRB1 Alleles and Latitude in Japanese Patients., MULTIPLE SCLEROSIS JOURNAL, Vol.21, No.6, p.810, 2015.05. |
| 31. |
S. Hayashida, K. Masaki, T. Yonekawa, N. Isobe, M. Watanabe, T. Matsushita, J. Kira, A Combined Neuroimaging and Neuropathological Study for Spinal Cord Lesions of Neuromyelitis Optica: with Special Reference to Lesion Distribution and Extension Patterns, MULTIPLE SCLEROSIS JOURNAL, Vol.21, No.6, p.804, 2015.05. |
| 32. |
Masaaki Niino, Shinya Sato, Toshiyuki Fukazawa, Satoshi Yoshimura, Shin Hisahara, Takuya Matsushita, Yuri Nakamura, Noriko Isobe, Kazuto Yoshida, Hideki Houzen, Yusei Miyazaki, Shun Shimohama, Eri Takahashi, Seiji Kikuchi, Jun-ichi Kira, Latitude and HLA-DRB1 Alleles Affect Emergence of CSF IgG Abnormalities in MS, MULTIPLE SCLEROSIS JOURNAL, Vol.22, No.3, p.406, 2016.03. |
| 33. |
Jun ichi Kira, Noriko Isobe, Helicobacter pylori infection and demyelinating disease of the central nervous system, Journal of Neuroimmunology, 10.1016/j.jneuroim.2018.06.017, 2019.04. |
| 34. |
Noriko Isobe, Emerging importance of big data in neuroimmunological research, Clinical and Experimental Neuroimmunology, 10.1111/cen3.12451, 2018.02. |
| 35. |
Noriko Isobe, Genetics in multiple sclerosis
Updates in the era of big data, Clinical and Experimental Neuroimmunology, 10.1111/cen3.12443, 2018.02. |
| 36. |
Noriko Isobe, Link between HLA alleles and anti-NMDAR encephalitis, Journal of Neurology, Neurosurgery and Psychiatry, 10.1136/jnnp-2018-319925, 2019.06. |
| 37. |
Noriko Isobe, American Academy of Neurology 2017 Annual Meeting, Clinical and Experimental Neuroimmunology, 10.1111/cen3.12402, 2017.08. |
| 38. |
Noriko Isobe, Jorge R. Oksenberg, Genetic studies of multiple sclerosis and neuromyelitis optica
Current status in European, African American and Asian populations, Clinical and Experimental Neuroimmunology, 10.1111/cen3.12078, 2014.01. |
| 39. |
Jun-Ichi Kira, Takuya Matsushita, Noriko Isobe, Takaaki Ishizu, Opticospinal multiple sclerosis in Japanese, Neurology Asia, 2008.01. |
| 40. |
Sreeram Ramagopalan, David Dyment, Rachel Farrell, Noriko Isobe, Multiple sclerosis, Autoimmune Diseases, 10.4061/2011/248758, 2011.12. |
| 41. |
Xu Zhang, Takayuki Fujii, Hidenori Ogata, Ryo Yamasaki, Katsuhisa Masaki, Yiwen Cui, Takuya Matsushita, Noriko Isobe, Jun-Ichi Kira, Cerebrospinal fluid cytokine/chemokine/growth factor profiles in idiopathic hypertrophic pachymeningitis., Journal of neuroimmunology, 10.1016/j.jneuroim.2019.01.010, Vol.330, pp.38-43, 2019.05. |
| 42. |
Yuri Nakamura, Laura Gaetano, Takuya Matsushita, Altermatt Anna, Till Sprenger, Ernst-Wilhelm Radue, Jens Wuerfel, Lorena Bauer, Michael Amann, Koji Shinoda, Noriko Isobe, Ryo Yamasaki, Takahiko Saida, Ludwig Kappos, Jun-Ichi Kira, A comparison of brain magnetic resonance imaging lesions in multiple sclerosis by race with reference to disability progression., Journal of neuroinflammation, 10.1186/s12974-018-1295-1, Vol.15, No.1, p.255, 2018.09. |
| 43. |
Facial onset sensory and motor neuronopathy症候群は早期からoral phase dysphagiaを呈する. |
| 44. |
西郷 和真, 吉村 怜, 泉川 友美, 松下 拓也, 磯部 紀子, 小池 敏靖, 宮本 勝一, 平野 牧人, 田原 康玄, 三木 哲郎, 北川 裕之, 吉良 潤一, 楠 進, 多発性硬化症の進行はChGn-1多型と関連する(Progression of multiple sclerosis is associated with ChGn-1 polymorphism), 臨床神経学, Vol.55, No.Suppl., p.S322, 2015.12. |
| 45. |
Satoshi Yoshimura, Tomomi Yonekawa, Noriko Isobe, Katsuhisa Masaki, Shinya Satou, Takuya Matsushita, Jun-ichi Kira, Distinct Genetic and Infectious Profiles between Multiple Sclerosis and Neuromyelitis Optica in Japanese Patients, NEUROLOGY, Vol.78, 2012.04. |
| 46. |
Satoshi Yoshimura, Noriko Isobe, Takuya Matsushita, Tomomi Yonekawa, Katsuhisa Masaki, Jun-ichi Kira, Common and Distinct Associations of HLA-DRB1 and-DPB1 Alleles with Neuromyelitis Optica and Multiple Sclerosis in Japanese, ANNALS OF NEUROLOGY, Vol.70, pp.S45-S46, 2011.10. |
| 47. |
Non-NMO MSとNMOにおけるHLA-DRB1アリル間のepistatic interaction解析. |
| 48. |
Non-NMO MSとNMOにおけるHLA-DRB1アリル間のepistatic interaction解析. |
| 49. |
Epidemiology of multiple sclerosis and neuromyelitis optica. |
