Updated on 2024/07/28

Information

 

写真a

 
MIZUNO DAISUKE
 
Organization
Faculty of Science Department of Physics Professor
School of Sciences Department of Physics(Joint Appointment)
Graduate School of Sciences Department of Physics(Joint Appointment)
Title
Professor
Contact information
メールアドレス
Tel
0926427026
Profile
research: biological soft matter, nonequilibrium statistical mechanics of life education
External link

Degree

  • PhD

Research Interests・Research Keywords

  • Research theme:non-equilibrium statistical mechanics of life

    Keyword:nonequilibrium mechanics, emergent properties of living systems, complex systems

    Research period: 2021.6

  • Research theme:Nonequilibrium mechanics and fluctuation Active gels, active glass, dense active matter

    Keyword:microrehology, nanobiology, biomechanics, nonequilibrium statistical mechanics, active gel, cancer, neuron,glycoprotein

    Research period: 2007.1 - 2012.2

Awards

  • 第4回 物理学会若手奨励賞(領域12)

    2011.8   日本物理学会  

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    生命現象は生体構成要素であるソフトマターの非平衡挙動と考えることができ、これを定量的に記述することが物理学の重要研究課題となっている。生命現象の一つの単位である細胞は、硬いタンパク質繊維からなる細胞骨格とモータータンパク質による力発生が複雑に絡み合った非線形・非平衡系だるが、実験的・理論的アプローチが困難でありった。水野氏は、アクチン(細胞骨格)、架橋剤、ミオシン(モータータンパク質)からなる細胞骨格のin vitroモデルシステムを設計し、細胞内部の力学的非平衡状態を再現した。また、Active-Passiveマイクロレオロジーと呼ばれる新しい実験的手法を開発し、システムの非平衡度を定量化することに成功した。モデルシステムにおける力学的特性と非平衡度の比較から、細胞内における非平衡・非線形動力学の詳細を明らかにした。これらの研究により得られたアプローチは、分子モーター等の分子部品の動作機構を周囲の溶媒との相互作用を含めて研究する手段であり、生きている状態の細胞に直接応用することで生命現象を理解する上で極めて有用である。領域12若手賞審査委員会は、これらの業績から判断して、水野氏の研究は、インパクト、独創性、先見性、発展性などにおいて、本賞を受賞するにふさわしいと判断した。

  • 文部科学大臣表彰 若手科学者賞

    2011.4   文部科学省  

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    生命現象は生体構成要素であるソフトマターの非平衡挙動であり、これを定量的に記述することが物理学の重要研究課題となっている。生命現象の一つの単位である細胞は、硬いたんぱく質繊維からなる細胞骨格とモーターたんぱく質による力発生が複雑に絡み合った非線形・非平衡系だが、実験的・理論的アプローチが困難であった。
    氏は、こうした生き物の非平衡挙動を定量評価するための方法論を初めて考案した。これを用いて、生き物が生きている程度(非平衡度)により、その物理的性質や生理的な応答を大きく変化させる物理的機構を明らかにしつつある。
    本研究成果は、数理物理的観点から生命現象を理解するものとして近年まますます高く評価されるようになっている。

  • S.M. Perren Research Award

    2006.8   European Society of Biomechanics  

Papers

  • Activity-dependent glassy cell mechanics II: Nonthermal fluctuations under metabolic activity Reviewed

    Katsuhiro Umeda, Kenji Nishizawa, Wataru Nagao, Shono Inokuchi, Yujiro Sugino, Hiroyuki Ebata, Daisuke Mizuno

    Biophysical Journal   122 ( 22 )   4395 - 4413   2023.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.bpj.2023.10.018

  • Activity-dependent glassy cell mechanics Ⅰ: Mechanical properties measured with active microrheology Reviewed International journal

    122 ( 10 )   1781 - 1793   2023.6

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    Language:English   Publishing type:Research paper (scientific journal)  

    Active microrheology was conducted in living cells by applying an optical-trapping force to vigorously-fluctuating tracer beads with feedback-tracking technology. The complex shear modulus G(\omega)=G'(\omega)-iG''(\omega) was measured in HeLa cells in an epithelial-like confluent monolayer. We found that G(\omega)\propto(-i\omega)^\frac{1}{2} over a wide range of frequencies (1 Hz < <10 kHz). Actin disruption and cell-cycle progression from G1 to S and G2 phases only had a limited effect on in living cells. On the other hand, was found to be dependent on cell metabolism; ATP-depleted cells showed an increased elastic modulus G'(\omega) at low frequencies, giving rise to a constant plateau such that G(\omega)=G_0+A(-i\omega)^\frac{1}{2}. Both the plateau and the additional frequency dependency \propto(-i\omega)^{1/2} of ATP-depleted cells are consistent with a rheological response typical of colloidal jamming. On the other hand, the plateau disappeared in ordinary metabolically active cells, implying that living cells fluidize their internal states such that they approach the critical jamming point.

    DOI: 10.1016/j.bpj.2023.04.011

    Other Link: https://www.sciencedirect.com/science/article/pii/S0006349523002412?via%3Dihub

  • Nonlinear master relation in microscopic mechanical response of semiflexible biopolymer networks Reviewed

    N Honda, K Shiraki, F van Esterik, S Inokuchi, H Ebata, D Mizuno

    New Journal of Physics   24 ( 5 )   053031 - 053031   2022.5

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1088/1367-2630/ac6902

  • Nonequilibrium Energetics of Molecular Motor Kinesin Reviewed International journal

    T. Ariga, M. Tomishige, and D. Mizuno

    Physical Review Letters   121   218101   2018.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1103/PhysRevLett.121.218101

  • Universal glass-forming behavior of in vitro and living cytoplasm Reviewed International journal

    Kenji Nishizawa, Kei Fujiwara, Masahiro Ikenaga, Nobushige Nakajo, Miho Yanagisawa, Daisuke Mizuno

    SCIENTIFIC REPORTS   7 ( 1 )   15143 - 15143   2017.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41598-017-14883-y

  • Feedback-tracking microrheology in living cells Reviewed International journal

    Kenji Nishizawa, Marcel Bremerich, Heev Ayade, Christoph F. Schmidt, Takayuki Ariga, Daisuke Mizuno

    Science Advances   3 ( 9 )   e1700318 - e1700318   2017.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1126/sciadv.1700318

  • Analytical Limit Distributions from Random Power-Law Interactions Reviewed International journal

    Irwin Zaid, Daisuke Mizuno

    PHYSICAL REVIEW LETTERS   117 ( 3 )   030602 - 030602   2016.7

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1103/PhysRevLett.117.030602

  • High-frequency affine mechanics and nonaffine relaxation in a model cytoskeleton International journal

    Daisuke Mizuno, Suguru Kinoshita, Lara Gay Villaruz

    PHYSICAL REVIEW E   89 ( 4 )   2014.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1103/PhysRevE.89.042711

  • Non-Gaussian athermal fluctuations in active gels Reviewed International journal

    T. Toyota, D. A. Head, C. F. Schmidt and D. Mizuno

    Soft Matter   7 ( 7 )   2011.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1039/c0sm00925c

  • High-resolution probing of cellular force transmission Reviewed International journal

    D. Mizuno, R. G. Bacabac, C. Tardin, D. Head, C. F. Schmidt

    Physical Review letters   102 ( 16 )   2009.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1103/PhysRevLett.102.168102

  • High-Resolution Probing of Cellular Force Transmission Reviewed International journal

    Daisuke Mizuno, Rommel Bacabac, Catherine Tardin, David Head, Christoph F. Schmidt

    PHYSICAL REVIEW LETTERS   102 ( 16 )   168102 - 168102   2009.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1103/PhysRevLett.102.168102

  • Nonequilibrium mechanics of active cytoskeletal networks Reviewed International journal

    D. Mizuno, C. Tardin, C. F. Schmidt, and F. C. MacKintosh

    Science   315 ( 5810 )   2007.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1126/science.1134404

  • Nonequilibrium mechanics of active cytoskeletal networks Reviewed

    Daisuke Mizuno, Catherine Tardin, C. F. Schmidt, F. C. MacKintosh

    SCIENCE   315 ( 5810 )   370 - 373   2007.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1126/science.1134404

  • A link between anomalous viscous loss and boson peak in soft jammed solids

    Yusuke Hara, Ryosuke Matsuoka, Hiroyuki Ebata, Daisuke Mizuno, Atsushi Ikeda

    2024.2

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    Language:Others  

    DOI: 10.48550/ARXIV.2402.00291

  • Non-Equilibrium Fluidization of Dense Active Suspension

    Yujiro Sugino, Hiroyuki Ebata, Yoshiyuki Sowa, Atsushi Ikeda, Daisuke Mizuno

    2024.1

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    DOI: 10.48550/ARXIV.2401.15658

  • Measuring fluctuating dynamics of sparsely crosslinked actin gels with dual-feedback nonlinear microrheology

    Kenji Nishizawa, Natsuki Honda, Shono Inokuchi, Hiroyuki Ebata, Takayuki Ariga, Daisuke Mizuno

    Physical Review E   108 ( 3 )   2023.9

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    Language:Others   Publishing type:Research paper (scientific journal)  

    DOI: 10.1103/physreve.108.034601

  • 非熱的なゆらぎが分子モーターキネシンを加速させる Invited Reviewed

    有賀隆行, 立石圭人, 富重道雄, 水野大介

    生物物理   63 ( 2 )   86 - 90   2023.3

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.2142/biophys.63.86

  • Activity-dependent glassy cell mechanics I : Mechanical properties measured with active microrheology International journal

    H. Ebata, K. Umeda, K. Nishizawa, W. Nagao, S. Inokuchi, Y. Sugino, T. Miyamoto, Daisuke Mizuno

    bioRxiv   122 ( 10 )   1781 - 1793   2022.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1101/2022.09.02.506288

  • Noise-Induced Acceleration of Single Molecule Kinesin-1. Reviewed International journal

    Takayuki Ariga, Keito Tateishi, Michio Tomishige, Daisuke Mizuno

    Physical review letters   127 ( 17 )   178101 - 178101   2021.10

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1103/PhysRevLett.127.178101

  • Feedback Microrheology in Soft Matter

    Kenji Nishizawa, Natsuki Honda, Masahiro Ikenaga, Shono Inokuchi, Yujiro Sugino, Takayuki Arigac, Daisuke Mizuno

    arXiv   2021.6

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    Language:Others   Publishing type:Research paper (scientific journal)  

    DOI: 10.48550/ARXIV.2106.05119

  • 光てこを用いたレーザー干渉法による粒子追跡

    井口 昇之, 水野 大介

    応用物理学会学術講演会講演予稿集   2021.1   786 - 786   2021.2

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    Language:Japanese  

    DOI: 10.11470/jsapmeeting.2021.1.0_786

  • Rapid local compression in active gels is caused by nonlinear network response. Reviewed International journal

    D Mizuno, C Tardin, C F Schmidt

    Soft matter   2020.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1039/c9sm02362c

  • Optimization of optical trapping and laser interferometry in biological cells Reviewed

    Yujiro Sugino, Masahiro Ikenaga, Daisuke Mizuno

    Applied Sciences (Switzerland)   10 ( 14 )   2020.7

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/app10144970

  • Optimization of Optical Trapping and Laser Interferometry in Biological Cells Invited Reviewed

    Yujiro Sugino, Masahiro Ikenaga, Daisuke Mizuno

    Applied Sciences   10 ( 14 )   4970 - 4970   2020.7

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    DOI: 10.3390/app10144970

  • Biophysics at Kyushu University Reviewed

    Ryo Akiyama, Masahiko Annaka, Daisuke Kohda, Hiroyuki Kubota, Yusuke Maeda, Nobuaki Matsumori, Daisuke Mizuno, Norio Yoshida

    Biophysical Reviews   12 ( 2 )   245 - 247   2020.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s12551-020-00643-2

  • Experimental and theoretical energetics of walking molecular motors under fluctuating environments. Reviewed International journal

    Takayuki Ariga, Michio Tomishige, Daisuke Mizuno

    Biophysical reviews   12 ( 2 )   503 - 510   2020.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s12551-020-00684-7

  • Biophysics at Kyushu University. Reviewed International journal

    Ryo Akiyama, Masahiko Annaka, Daisuke Kohda, Hiroyuki Kubota, Yusuke Maeda, Nobuaki Matsumori, Daisuke Mizuno, Norio Yoshida

    Biophysical reviews   12 ( 2 )   245 - 247   2020.4

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    Language:English  

    DOI: 10.1007/s12551-020-00643-2

  • Experimental and theoretical energetics of walking molecular motors under fluctuating environments Reviewed

    Takayuki Ariga, Michio Tomishige, Daisuke Mizuno

    Biophysical Reviews   12 ( 2 )   503 - 510   2020.1

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    DOI: 10.1007/s12551-020-00684-7

  • 生体分子モーター・キネシンの"散逸"を計測する Reviewed

    有賀 隆行, 富重 道雄, 水野 大介

    生物物理   59 ( 6 )   300 - 304   2019

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    Molecular motors are nonequilibrium open systems that convert chemical energy to mechanical work. The nonequilibrium energetics of single molecule kinesin were investigated by measuring the motion of an attached probe particle and its response to external forces with optical tweezers. The sum of the heat dissipation estimated from the violation of the fluctuation-response relation and the output power was inconsistent with the input free energy rate, indicating that large internal dissipation exists. Here we introduce the theoretical basis of the dissipation measurement and our recent experimental results, discussing the physiological implications of the hidden dissipation in the kinesin motor.

    DOI: 10.2142/biophys.59.300

  • Nonequilibrium Energetics of Molecular Motor Kinesin Reviewed International journal

    Takayuki Ariga, Michio Tomishige, Daisuke Mizuno

    PHYSICAL REVIEW LETTERS   121 ( 21 )   218101 - 218101   2018.11

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    DOI: 10.1103/PhysRevLett.121.218101

  • Nonequilibrium Energetics of Single Molecule Motor, Kinesin-1

    Takayuki Ariga, Michio Tomishige, Daisuke Mizuno

    BIOPHYSICAL JOURNAL   114 ( 3 )   509A - 509A   2018.2

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    Language:English  

    DOI: 10.1016/j.bpj.2017.11.2783

  • Determination of sour environment from equal hydrogen concentration approach

    Takuya Hara, Taishi Fujishiro, Daisuke Mizuno, Nobuyuki Ishikawa, Eiji Tada, Mitsuo Kimura

    28th International Ocean and Polar Engineering Conference, ISOPE 2018 Proceedings of the 28th International Ocean and Polar Engineering Conference, ISOPE 2018   2018-June   202 - 205   2018.1

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  • Feedback-tracking microrheology in living cells Reviewed International journal

    Kenji Nishizawa, Marcel Bremerich, Heev Ayade, Christoph F. Schmidt, Takayuki Ariga, Daisuke Mizuno

    SCIENCE ADVANCES   3 ( 9 )   e1700318   2017.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1126/sciadv.1700318

  • Feedback-tracking microrheology in living cells Reviewed

    Kenji Nishizawa, Marcel Bremerich, Heev Ayade, Christoph F. Schmidt, Takayuki Ariga, Daisuke Mizuno

    Science Advances   3 ( 9 )   2017.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1126/sciadv.1700318

  • Non-Gaussian limit fluctuations in active swimmer suspensions Reviewed International journal

    Takashi Kurihara, Msato Aridome, Heev Ayade, Irwin Zaid, Daisuke Mizuno

    PHYSICAL REVIEW E   95 ( 3 )   030601 - 030601   2017.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1103/PhysRevE.95.030601

  • High-frequency affine mechanics and nonaffine relaxation in a model cytoskeleton Reviewed International journal

    David A. Head, Emi Ikebe, Akiko Nakamasu, Peijuan Zhang, Lara Gay Villaruz, Suguru Kinoshita, Shoji Ando, Daisuke Mizuno

    PHYSICAL REVIEW E   89 ( 4 )   042711 - 042711   2014.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1103/PhysRevE.89.042711

  • Athermal Fluctuations of Probe Particles in Active Cytoskeletal Network Reviewed

    Irwin Zaid, Heev L. Ayade, Daisuke Mizuno

    BIOPHYSICAL JOURNAL   106 ( 2 )   171A - 171A   2014.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.bpj.2013.11.973

  • Non-Gauss Athermal Fluctuations in Bacterial Bath Reviewed

    Masato Aridome, Takashi Kurihara, Heev Ayade, Irwin Zaid, Daisuke Mizuno

    BIOPHYSICAL JOURNAL   106 ( 2 )   580A - 580A   2014.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.bpj.2013.11.3218

  • Local mechanical response in semiflexible polymer networks subjected to an axisymmetric prestress Reviewed International journal

    David A. Head, Daisuke Mizuno

    PHYSICAL REVIEW E   88 ( 2 )   022717 - 022717   2013.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1103/PhysRevE.88.022717

  • High-resolution microrheology in the pericellular matrix of prostate cancer cells Reviewed International journal

    Nadja Nijenhuis, Daisuke Mizuno, Jos A. E. Spaan, Christoph F. Schmidt

    JOURNAL OF THE ROYAL SOCIETY INTERFACE   9 ( 73 )   1733 - 1744   2012.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1098/rsif.2011.0825

  • "High-resolution microrheology in the pericellular matrix of prostate cancer cells" Reviewed International journal

    N. Nijenhuis, D. Mizuno, J. A. E. Spaan, and C. F. Schmidt

    J. Royal Society Interface   2012.6

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  • Non-Gaussian athermal fluctuations in active gels Reviewed

    Toshihiro Toyota, David A. Head, Christoph F. Schmidt, Daisuke Mizuno

    Soft Matter   7 ( 7 )   3234 - 3239   2011

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1039/c0sm00925c

  • Nonlocal fluctuation correlations in active gels Reviewed

    D. A. Head, D. Mizuno

    Physical Review E - Statistical, Nonlinear, and Soft Matter Physics   81 ( 4 )   2010.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1103/PhysRevE.81.041910

  • 21pEF-3 生き物の非平衡力学物性(21pEF 若手奨励賞受賞記念講演,領域12(ソフトマター物理,化学物理,生物物理))

    水野 大介

    日本物理学会講演概要集   65 ( 1 )   384 - 384   2010.3

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    Language:Japanese  

  • Viscoelastic response of a model endothelial glycocalyx Reviewed International journal

    Nadja Nijenhuis, Daisuke Mizuno, Jos A. E. Spaan, Christoph F. Schmidt

    PHYSICAL BIOLOGY   6 ( 2 )   025014 - 025014   2009.6

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1088/1478-3975/6/2/025014

  • Microrheology of the pericellular matrix Reviewed

    Nadja Nijenhuis, Daisuke Mizuno, Jos A. E. Spaan, Christoph F. Schmidt

    BIOPHYSICAL JOURNAL   96 ( 3 )   523A - 523A   2009.2

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  • High-bandwidth viscoelastic properties of aging colloidal glasses and gels Reviewed

    S. Jabbari-Farouji, M. Atakhorrami, D. Mizuno, E. Eiser, G. H. Wegdam, F. C. MacKintosh, Daniel Bonn, C. F. Schmidt

    Physical Review E - Statistical, Nonlinear, and Soft Matter Physics   78 ( 6 )   2008.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1103/PhysRevE.78.061402

  • Active and passive microrheology in equilibrium and nonequilibrium systems Reviewed

    D. Mizuno, D. A. Head, F. C. MacKintosh, C. F. Schmidt

    Macromolecules   41 ( 19 )   7194 - 7202   2008.10

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/ma801218z

  • Effective temperatures from the fluctuation-dissipation measurements in soft glassy materials Reviewed

    S. Jabbari-Farouji, D. Mizuno, D. Derks, G. H. Wegdam, F. C. MacKintosh, C. F. Schmidt, D. Bonn

    EPL   84 ( 2 )   2008.10

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1209/0295-5075/84/20006

  • Microrheology of hyaluronan solutions: Implications for the endothelial glycocalyx Reviewed International journal

    Nadja Nijenhuis, Daisuke Mizuno, Christoph F. Schmidt, Hans Vink, Jos A. E. Spaan

    BIOMACROMOLECULES   9 ( 9 )   2390 - 2398   2008.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/bm800381z

  • "Round versus flat : bone cell norphology, elasticity, and mechanosensing" Journal of biomechanics 41, (7), pp.1590-pp.1598b (2008) Reviewed International journal

    R. G. Bacabac, D. Mizuno, A. Vatsa, C.F. Schmidt, F.C. MacKintosh, J. Van Loon, J. Klein-Nulend, and T. Smit

    Journal of biomechanics   2008.8

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  • Round versus flat: Bone cell morphology, elasticity, and mechanosensing (vol 41, pg 1590, 2008) Reviewed

    Rommel G. Bacabac, Daisuke Mizuno, Christoph F. Schmidt, Fred C. MacKintosh, Jack J. W. A. Van Loon, Jenneke Klein-Nulend, Theo H. Smit

    JOURNAL OF BIOMECHANICS   41 ( 12 )   2786 - 2786   2008.8

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    DOI: 10.1016/j.jbiomech.2008.01.035

  • Short-time inertial response of viscoelastic fluids measured with Brownian motion and with active probes Reviewed

    M. Atakhorrami, D. Mizuno, G. H. Koenderink, T. B. Liverpool, F. C. MacKintosh, C. F. Schmidt

    Physical Review E - Statistical, Nonlinear, and Soft Matter Physics   77 ( 6 )   2008.6

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    DOI: 10.1103/PhysRevE.77.061508

  • Laser trapping and laser interferometry for high-bandwidth micromechanical probing of biomaterials

    D. Mizuno, M. Atakhorrami, K. M. Addas, J. X. Tang, G. H. Koenderink, F. C. MacKintosh, C. F. Schmidt

    Asia Optical Fiber Communication and Optoelectronic Exposition and Conference, AOE 2008 Asia Optical Fiber Communication and Optoelectronic Exposition and Conference, AOE 2008   2008

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    DOI: 10.1364/aoe.2008.sap1

  • Round versus flat Bone cell morphology, elasticity, and mechanosensing Reviewed

    Rommel G. Bacabac, Daisuke Mizuno, Christoph F. Schmidt, Fred C. MacKintosh, Jack J.W.A. Van Loon, Jenneke Klein-Nulend, Theo H. Smit

    Journal of Biomechanics   41 ( 7 )   1590 - 1598   2008

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jbiomech.2008.01.031

  • Linear and nonlinear laser-trapping microrheology Reviewed

    C. F. Schmidt, D. Mizuno

    OPTICAL TRAPPING AND OPTICAL MICROMANIPULATION IV   6644   2007.9

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    Language:English   Publishing type:Research paper (other academic)  

    DOI: 10.1117/12.739441

  • Fluctuation-dissipation theorem in an aging colloidal glass Reviewed International journal

    Sara Jabbari-Farouji, Daisuke Mizuno, Maryam Atakhorrami, Fred C. MacKintosh, Christoph F. Schmidt, Erika Eiser, Gerard H. Wegdam, Daniel Bonn

    PHYSICAL REVIEW LETTERS   98 ( 10 )   108302 - 108302   2007.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1103/PhysRevLett.98.108302

  • Microrheology of a swollen lyotropic lamellar phase Reviewed

    Yasuyuki Kimura, Daisuke Mizuno

    Molecular Crystals and Liquid Crystals   478 ( 1 )   3/[759] - 13/[769]   2007.1

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    DOI: 10.1080/15421400701739170

  • Non-equilibrium mechanics of in-vitro and in-vivo active cytoskeletal networks Reviewed International journal

    Daisuke Mizuno, Catherine Tardin, Beth Percha, Frederick MacKintoshi, Christoph Schmidt

    BIOPHYSICAL JOURNAL   315 ( 5810 )   304A - 304A   2007.1

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  • Bio imaging of intracellular NO production in single bone cells after mechanical stimulation Reviewed International journal

    Aviral Vatsa, Daisuke Mizuno, Theo H. Smit, Christoph F. Schmidt, Fred C. MacKintosh, Jenneke Klein-Nulend

    JOURNAL OF BONE AND MINERAL RESEARCH   21 ( 11 )   1722 - 1728   2006.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1359/jbmr.060720

  • Hierarchical transport of nanoparticles in a lyotropic lamellar phase Reviewed

    Yasuyuki Kimura, Teppei Mori, Akira Yamamoto, Daisuke Mizuno

    Journal of Physics Condensed Matter   17 ( 31 )   S2937 - S2942   2005.8

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    DOI: 10.1088/0953-8984/17/31/021

  • Hierarchical dynamics of nano-particles in lyotropic lamellar phase Reviewed

    Yasuyuki Kimura, Teppei Mori, Akira Yamamoto, Daisuke Mizuno

    Molecular Crystals and Liquid Crystals   435   51/[711] - 61/[721]   2005

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    DOI: 10.1080/15421400590956324

  • Electrophoretic microrheology of a dilute lamellar phase: relaxation mechanisms in frequency-dependent mobility of nanometer-sized particles between soft membranes. Reviewed International journal

    Daisuke Mizuno, Yasuyuki Kimura, Reinosuke Hayakawa

    Physical review. E, Statistical, nonlinear, and soft matter physics   70 ( 1 Pt 1 )   011509 - 011509   2004.7

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  • Electrophoretic microrheology of a dilute lamellar phase Relaxation mechanisms in frequency-dependent mobility of nanometer-sized particles between soft membranes Reviewed

    Daisuke Mizuno, Yasuyuki Kimura, Reinosuke Hayakawa

    Physical Review E - Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics   70 ( 1 )   2004.1

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    DOI: 10.1103/PhysRevE.70.011509

  • Dielectric response in dilute lyotropic lamellar and sponge phases of a nonionic surfactant Reviewed

    Daisuke Mizuno, Takuji Nishino, Yasuyuki Kimura, Reinosuke Hayakawa

    Physical Review E - Statistical, Nonlinear, and Soft Matter Physics   67 ( 6 1 )   2003.6

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  • Dielectric response in dilute lyotropic lamellar and sponge phases of a nonionic surfactant Reviewed

    D Mizuno, T Nishino, Y Kimura, R Hayakawa

    PHYSICAL REVIEW E   67 ( 6 )   61505   2003.6

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    DOI: 10.1103/PhysRevE.67.061505

  • Dielectric response in dilute lyotropic lamellar and sponge phases of a nonionic surfactant. Reviewed International journal

    Daisuke Mizuno, Takuji Nishino, Yasuyuki Kimura, Reinosuke Hayakawa

    Physical review. E, Statistical, nonlinear, and soft matter physics   67 ( 6 Pt 1 )   061505 - 061505   2003.6

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  • Wide-band spectroscopy of dynamic electrophoretic mobility and its application to microrheology. Invited Reviewed International journal

    Mizuno, D (Mizuno, D); Kimura, Y (Kimura, Y); Hayakawa, R (Hayakawa, R)

    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY   225   U631 - U631   2003.3

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  • Dielectric response in dilute lyotropic lamellar and sponge phases of a nonionic surfactant Reviewed

    Daisuke Mizuno, Takuji Nishino, Yasuyuki Kimura, Reinosuke Hayakawa

    Physical Review E - Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics   67 ( 6 )   2003.1

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    DOI: 10.1103/PhysRevE.67.061505

  • Electrophoretic Microrheology in a Dilute Lamellar Phase of a Nonionic Surfactant

    Daisuke Mizuno, Yasuyuki Kimura, Reinosuke Hayakawa

    Physical Review Letters   87 ( 8 )   2001.8

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    DOI: 10.1103/physrevlett.87.088104

  • Electrophoretic microrheology in a dilute lamellar phase of a nonionic surfactant Reviewed

    Daisuke Mizuno, Yasuyuki Kimura, Reinosuke Hayakawa

    Physical Review Letters   87 ( 8 )   88104 - 1-88104-4   2001.8

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    DOI: 10.1103/PhysRevLett.87.088104

  • Measurement of liquid surface properties by laser-induced surface deformation spectroscopy

    K. Sakai, D. Mizuno, K. Takagi

    Physical Review E   63 ( 4 )   2001.3

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    DOI: 10.1103/physreve.63.046302

  • Dynamic Electrophoretic Mobility of Colloidal Particles Measured by the Newly Developed Method of Quasi-elastic Light Scattering in a Sinusoidal Electric Field

    D. Mizuno, Y. Kimura, R. Hayakawa

    Langmuir   16 ( 24 )   9547 - 9554   2000.11

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    DOI: 10.1021/la000821h

  • New Measurement Method of Complex Electrophoretic Mobility of Charged Colloids by Quasi-Elastic Light Scattering

    Daisuke Mizuno, Yasuyuki Kimura, Reinosuke Hayakawa

    Japanese Journal of Applied Physics   39 ( Part 2, No. 11B )   L1197 - L1199   2000.11

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    DOI: 10.1143/jjap.39.l1197

  • Observation of Slow Dynamics on a Liquid Surface by Time-Resolved Ripplon Light-Scattering Spectroscopy

    D. Mizuno, K. Hattori, N. Sakamoto, K. Sakai, K. Takagi

    Langmuir   16 ( 2 )   643 - 648   2000.1

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    DOI: 10.1021/la9903954

  • Dynamic measurement of surface properties with Ripplon spectroscopy Invited Reviewed International journal

    Mizuno, D (Mizuno, D); Hattori, K (Hattori, K); Sakai, K (Sakai, K); Takagi, K (Takagi, K)

    1998 IEEE ULTRASONICS SYMPOSIUM - PROCEEDINGS, VOLS 1 AND 2   1121 - 1124   1900

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Books

  • 【「マイクロレオロジー」】多重feedback制御されたマイクロレオロジーによる生体試料計測

    西澤 賢治, 水野 大介

    (公社)日本油化学会  2023.9 

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    Language:Japanese  

    光トラップとレーザー干渉法を用いたマイクロレオロジー(MR)計測について解説する。生体試料は希少なことが多く,レオロジーの時空間スケール依存性も顕著であるためにMRが有効であるが,細胞のように揺らぎ(流動)が大きく,また,光によってダメージを受ける生体試料の計測は困難であった。私達は,プローブ粒子に加わる力とその位置をそれぞれfeedback制御するMR計測によって,生体試料を始めとするソフトマターの低侵襲かつ精密な力学計測を可能にした。本稿ではこの最新の手法について説明した後,計測例として細胞内部の線形粘弾性と外力誘起による細胞骨格の非線形揺らぎについて紹介する。(著者抄録)

  • 【バイオマテリアルとレオロジー】細胞質と細胞骨格の複合系としての細胞内レオロジー

    江端 宏之, 水野 大介

    日本バイオマテリアル学会  2023.7 

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    細胞内部が周囲力学環境から受ける様々な応力と,細胞質内のモーターたんぱく質・酵素から受ける力により,どのように変形し流動するかを知るためには,細胞質のレオロジーを明らかにする必要がある.細胞内部は生体高分子ゲルとして振る舞う細胞骨格と,その間隙を埋めるリポソーム,たんぱく質や核酸からなる高濃度コロイド懸濁液からなる.これまで,細胞の機械的特性を調べる上で,細胞骨格が注目されてきたが,骨格間隙の細胞質レオロジーは未解明であった.本稿では,当研究グループにて得られた細胞質レオロジーについての知見を細胞内レオロジーの測定法と共に紹介する.(著者抄録)

  • 特集 生物物理学の進歩-生命現象の定量的理解へ向けて Ⅰ.分子レベル 生きている細胞の非平衡力学

    水野 大介, 杉野 裕次郎

    株式会社医学書院  2021.6 

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    Language:Others  

    DOI: 10.11477/mf.2425201349

  • 生体の科学 Vol.72 No.3 2021年 06月号 特集 生物物理学の進歩——生命現象の定量的理解へ向けて

    水野大介、杉野裕次郎( Role: Joint author)

    医学書院  2021.6 

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    Responsible for pages:生体の科学 Vol.72 No.3 2021年 06月号 特集 生物物理学の進歩——生命現象の定量的理解へ向けて ■Ⅰ.分子レベル 「生きている細胞の非平衡力学」   Language:Japanese   Book type:Scholarly book

  • 実験医学 増刊 相分離 メカニズムと疾患

    水野大介、藤原誠、井口昇之、杉野裕次郎( Role: Joint author)

    羊土社  2021.6 

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    Responsible for pages:第4章 解析技術 1. 液滴混み合い状態としての細胞内レオロジー   Language:Japanese   Book type:Scholarly book

  • 相分離 : メカニズムと疾患 : “膜のないオルガネラ"はいかに機能するか? 神経変性疾患・ウイルス感染とどう関わるか?

    廣瀬, 哲郎, 加藤, 昌人, 中川, 真一

    羊土社  2021.6 

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    Responsible for pages:総ページ数:221p   Language:Japanese  

  • Cell Mechanochemistry. Biological Systems and Factors Inducing Mechanical Stress, Such as Light, Pressure and Gravity, Chapter 2

    Rommel G. Bacabac, Daisuke Mizuno, Gijsje H. Koenderink( Role: Joint author)

    Transworld Research Network  2010.10 

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    Language:English   Book type:Scholarly book

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Presentations

  • Levy statistics and dynamics in active cytoskeletons Invited International conference

    Daisuke Mizuno

    2013 SPP Physics Congress  2013.10 

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    Event date: 2013.10

    Language:English   Presentation type:Oral presentation (general)  

    Country:Philippines  

  • Levy statistics and dynamics in active cytoskeletons Invited International conference

    Daisuke Mizuno

    Taiwan International Workshop on Biological Physics and Complex Systems (BioComplex-Taiwan-2013)  2013.7 

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    Event date: 2013.7

    Language:English   Presentation type:Oral presentation (general)  

    Country:Taiwan, Province of China  

  • Mechano-sensing and Active Cytoskeleton Invited International conference

    Daisuke Mizuno, R. G. Bacabac, D.A. Head and Christoph Schmidt

    inernational symposium on emchanobiology  2011.11 

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    Event date: 2011.11

    Language:Others   Presentation type:Oral presentation (general)  

    Country:China  

  • 揺動散逸定理を破る生き物の非平衡揺らぎの統計分布 Invited

    水野 大介

    第69回日本物理学会年次大会シンポジウム「動的ゆらぎの普遍法則」  2014.3 

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    Country:Japan  

  • Non-Gauss a-thermal fluctuations in active cytoskeletons Invited International conference

    Daisuke Mizuno, Heev Ayade

    Biological & Pharmaceutical Complex Fluids: New Trends in Characterizing Microstructure, Interactions & Properties An ECI Conference  2012.8 

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    Country:Portugal  

  • 揺動散逸定理を破る非平衡揺らぎの時空間構造 Invited

    水野 大介

    第 17 回久保記念シンポジウム「ゆらぎのなかの構造」  2012.10 

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    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京, 学士会館   Country:Japan  

  • 濃厚コロイド懸濁液における混み合い由来のべき乗則緩和現象

    松岡亮佑, 井口昇之, 江端宏之, 池田昌司, 原雄介, 水野大介

    日本物理学会 第76回年次大会  2023.3 

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    Event date: 2023.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • 遊走大腸菌濃厚懸濁液の非平衡レオロジー

    杉野裕次郎, 江端宏之, 曽和義幸, 水野大介

    日本物理学会 第76回年次大会  2023.3 

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    Event date: 2023.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • 代謝依存的な細胞質の非平衡力学

    江端宏之, 水野大介

    日本物理学会 第76回年次大会  2023.3 

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    Event date: 2023.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • 細胞内力学の理解に向けた遊走微生物系の物理計測

    濱田啓聖, 安部共法, 杉野裕次郎, 江端宏之, 曽和義幸, 水野大介

    日本物理学会 第76回年次大会  2023.3 

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    Event date: 2023.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • 局所的な外力印加下の濃厚コロイド懸濁液のマイクロレオロジー

    吉良和真, 荊原佳祐, 柳島大輝, 水野大介

    日本物理学会 第76回年次大会  2023.3 

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    Event date: 2023.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • 限界安定性が混み合い系のレオロジーに与える影響

    原雄介, 松岡亮佑, 江端宏之, 水野大介, 池田昌司

    日本物理学会 第76回年次大会  2023.3 

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    Event date: 2023.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • 微生物が遊走する高分子・コロイド懸濁系の非平衡ダイナミクス

    安部共法, 濱田啓聖, 杉野裕次郎, 江端宏之, 水野大介

    第127回日本物理学会九州支部例会  2022.12 

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    Event date: 2022.12

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • 代謝抑制が誘導する細胞質粘弾性のエイジング現象

    田尾優樹, 江端宏之, 水野大介

    第127回日本物理学会九州支部例会  2022.12 

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    Event date: 2022.12

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • 濃厚バクテリア懸濁液の非平衡レオロジー

    杉野裕次郎, 江端宏之, 曽和義幸, 水野大介

    2022 ソフトマター研究会  2022.11 

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    Event date: 2022.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • 代謝依存点細胞骨格非依存の細胞質レオロジー特性

    江端宏之, 水野大介

    2022 ソフトマター研究会  2022.11 

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    Event date: 2022.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • Critical Jamming and gel rheology of droplet suspensions in living cells Invited

    2022.10 

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    Event date: 2022.10

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  • 濃厚バクテリア懸濁液のアクティブレオロジー

    杉野裕次郎, 江端宏之, 水野大介

    第70回レオロジー討論会  2022.10 

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    Event date: 2022.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • Critical Jamming and gel rheology of droplet suspensions in living cells Invited International conference

    25 th Anniversary Symposium for German-Japanese Non-Equilibrium Statistical Physics  2022.9 

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    Event date: 2022.9

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  • アクティブな濃厚懸濁系としての細胞質レオロジー

    水野大介, 松岡亮佑, 井口昇之, 杉野裕次郎

    日本物理学会 2022年秋季大会  2022.9 

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    Event date: 2022.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • 濃厚エマルジョンにおけるこみあい由来の粘弾性緩和挙動

    松岡亮佑, 井口昇之, 江端宏之, 池田昌司, 水野大介

    日本物理学会 2022年秋季大会  2022.9 

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    Event date: 2022.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • 基材弾性率により形態制御された細胞の細胞質流動特性

    江端宏之, 水野大介

    日本物理学会 2022年秋季大会  2022.9 

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    Event date: 2022.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • Glassy cytoplasm driven by non-thermal forces International conference

    Soft Matter Physics: from the perspective of the essential heterogeneity  2018.12 

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    Event date: 2020.4

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  • Optical trap and laser interferometry in living cells

    Daisuke Mizuno, Umeda Katsuhiro, Sugino Yujiro, Kenji Nishizawa

    Biomedical Imaging and Sensing Conference 2019, BISC 2019  2019.1 

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    Event date: 2019.4

    Language:English  

    Country:Japan  

  • Non-Gaussian limit fluctuations in active swimmer suspensions Invited International conference

    T. Kurihara, Y. Ando, I. Zaid and D. Mizuno

    American Physical Society  2019.3 

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    Event date: 2019.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • Non-Gaussian limit fluctuations in active swimmer suspensions International conference

    D. Mizuno

    Soft Matter Physics: from the perspective of the essential heterogeneity  2018.12 

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    Event date: 2018.12

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  • Mechanical activity induces fragile to strong transition of glassy cytoplasm in living cells International conference

    K. Nishizawa, D. Mizuno

    8th World Congress of Biomechanics  2020.4 

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    Event date: 2018.7

    Language:English   Presentation type:Oral presentation (general)  

    Country:Ireland  

  • Universal glass-forming behavior of in vitro and living cytoplasm ~its similarity to droplet suspensions?~ International conference

    D. Mizuno

    EMBO | EMBL Symposium: Cellular Mechanisms Driven by Liquid Phase Separation  2018.5 

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    Event date: 2018.5

    Language:English   Presentation type:Oral presentation (general)  

    Country:Germany  

  • Enhanced Viscosity of the Cytoplasm at the Later Stage International conference

    F. Esterik, M. Ikenaga, H. Niwa, D. Mizuno

    8th World Congress of Biomechanics  2020.4 

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    Event date: 2018.4 - 2020.7

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  • Non-Gauss athermal fluctuations in Bacterial bath International conference

    58th annual meeting of Biophysical Society  2014.2 

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    Event date: 2014.2

    Language:English  

    Country:United States  

  • Athermal Fluctuations of Probe Particles in Active Cytoskeletal Network International conference

    Daisuke Mizuno, Heev Ayade, Irwin Zaid

    58th annual meeting of Biophysical Society  2014.2 

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    Event date: 2014.2

    Language:English  

    Country:United States  

  • Non-Gauss athermal fluctuations in Bacterial bath International conference

    Daisuke Mizuno, Masato Aridome, takasi kurihara, Heev Ayade, Irwin Zaid

    KITP conference "Active Processes in Living and Nonliving Matter"  2014.2 

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    Event date: 2014.2

    Language:English  

    Country:United States  

  • Athermal Fluctuations of Probe Particles in Active Cytoskeletal Network International conference

    Daisuke Mizuno, Irwin Zaid

    KITP conference "Active Processes in Living and Nonliving Matter"  2014.2 

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    Event date: 2014.2

    Language:English   Presentation type:Oral presentation (general)  

    Country:United States  

  • Levy statistics and dynamics in active cytoskeletons Invited International conference

    Daisuke Mizuno

    15th SPVM National Physics Conference in Davao  2013.10 

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    Event date: 2013.10

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  • Microrheology study of crowding effects on cell mechanics International conference

    Daisuke Mizuno, Kenji Nishizawa, Miho Yanagisawa, Kei Fujiwara

    International Soft Matter Conference  2013.9 

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    Event date: 2013.9

    Language:English  

    Country:Italy  

  • Levy statistics and dynamics in active cytoskeletons International conference

    Daisuke Mizuno, Heev Ayade, Irwin Zaid

    International Soft Matter Conference  2013.9 

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    Event date: 2013.9

    Language:English  

    Country:Italy  

  • Laser trapping and laser interferometry for high-bandwidth micromechanical probing of biomaterials

    Daisuke Mizuno, M. Atakhorrami, K. M. Addas, J. X. Tang, G. H. Koenderink, F. C. MacKintosh, C. F. Schmidt

    Asia Optical Fiber Communication and Optoelectronic Exposition and Conference, AOE 2008  2008.1 

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    Event date: 2008.10 - 2008.11

    Language:English  

    Country:China  

  • Linear and nonlinear laser-trapping microrheology

    C. F. Schmidt, D. Mizuno

    Optical Trapping and Optical Micromanipulation IV  2007.12 

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    Event date: 2007.8

    Language:English  

    Country:United States  

  • Dynamics of nano-sized colloidal particles in a lyotropic lamellar phase

    Yasuyuki Kimura, Daisuke Mizuno

    3rd International Symposium on Slow Dynamics in Complex Systems  2004.4 

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    Event date: 2003.11

    Language:English  

    Country:Japan  

  • Dynamic measurement of surface properties with Ripplon spectroscopy

    D. Mizuno, K. Hattori, K. Sakai, K. Takagi

    Proceedings of the 1998 International Ultrasonics Symposium  1998.12 

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    Event date: 1998.10

    Language:English  

    Country:Other  

  • 1AD09 非イオン性界面活性剤スポンジ相における2分子膜のダイナミックス

    木村 康之, 水野 大介, 大泉 淳一, 早川 禮之助

    液晶討論会講演予稿集  1997.9 

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    Language:Japanese  

    Country:Japan  

    We have studied the sponge phase (L_3) of binary mixture of C_<12>E_5 and water by the dynamic light scattering technique. At the concentration above 2w&#37;, an almost single relaxation related with the cooparative diffusion of membranes is detected. The dynamic correlation lengh is evaluated from the diffusion constant to be a little larger than that obtained for the L_α phase. At the concentration below 2w&#37;, we can find the crossover behavior Γ∝q^2 to Γ∝q^3 in the dispersion relation between the inverse correlation time Γ and the scattering wavenumber q.

  • 24aZD-2 交流電場下での荷電コロイド粒子のダイナミックス

    水野 大介, 木村 康之, 早川 禮之助

    日本物理学会講演概要集  2000.3 

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    Language:Japanese  

    Country:Japan  

  • 24aZD-1 コロイド結晶の揺らぎのダイナミックス

    磯野 洋, 小俣 一由, 水野 大介, 木村 康之, 早川 禮之助

    日本物理学会講演概要集  2000.3 

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    Language:Japanese  

    Country:Japan  

  • 25aXA-11 複素電気泳動易動度スペクトロスコピーを用いたコロイド分散系のキャラクタリゼーション

    水野 大介, 木村 康之, 早川 禮之助

    日本物理学会講演概要集  2000.9 

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    Language:Japanese  

    Country:Japan  

  • 21pVA-4 生きた細胞(骨格)の非平衡動力学(21pVA 領域11シンポジウム:非平衡ゆらぎ,領域11(統計力学,物性基礎論,応用数学,力学,流体物理))

    水野 大介

    日本物理学会講演概要集  2008.8 

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    Language:Japanese  

    Country:Japan  

  • 30pVC-1 細胞牽引力の力学変換過程(30pVC 生物物理,領域12(ソフトマター物理,化学物理,生物物理))

    水野 大介, Bacabac R. G., Tardin C., Head D. A., Schmidt C. F.

    日本物理学会講演概要集  2009.3 

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    Language:Japanese  

    Country:Japan  

  • 28pVC-16 生きた細胞骨格の非平衡揺らぎ(28pVC 生物物理,領域12(ソフトマター物理,化学物理,生物物理))

    豊田 聖啓, 木下 英, 坂本 隼人, 木村 康之, Scmidt C. F., 水野 大介

    日本物理学会講演概要集  2009.3 

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    Language:Japanese  

    Country:Japan  

  • 26pPSA-42 生きた細胞骨格の非平衡揺らぎ(領域12ポスターセッション,領域12,ソフトマター物理,化学物理,生物物理)

    豊田 聖啓, 木下 英, 山本 直樹, 坂本 隼人, 木村 康之, Schmidt C. F., 水野 大介

    日本物理学会講演概要集  2009.8 

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    Language:Japanese  

    Country:Japan  

  • Non-Gauss athermal fluctuations in active cytoskeletons Invited

    Daisuke Mizuno

    2012.9 

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    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  • 力生成する細胞(骨格)が示す非平衡揺らぎの統計分布 Invited

    水野 大介

    第2回ソフトマター研究会  2012.9 

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    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:福岡   Country:Japan  

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MISC

Professional Memberships

  • 日本物理学会

  • 細胞生物学会

  • 生物物理学会

  • biophysical socioety

  • 高分子学会

Committee Memberships

  • 九州支部会委員   九州支部会委員   Domestic

    2011.9 - 2012.9   

Academic Activities

  • その他

    第119回日本物理学会九州支部例会  2013.11

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    Type:Competition, symposium, etc. 

  • Other International contribution

    Self-organization and Emergent Dynamics in Active Soft Matter  ( Yukawa Insititute for Theoretical Physics, Kyoto University Japan Japan ) 2013.2

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    Type:Competition, symposium, etc. 

  • Other International contribution

    Self-organization and Emergent Dynamics in Active Soft Matterhtml  ( Panasonic Auditorium, Yukawa Hall, Yukawa Insititute for Theoretical Physics, Kyoto University Japan Japan ) 2013.2

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    Type:Competition, symposium, etc. 

  • その他

    第118回日本物理学会九州支部例会  2012.12

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    Type:Competition, symposium, etc. 

  • 日本生物物理学会誌

    2012.4 - 2014.3

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    Type:Academic society, research group, etc. 

  • その他

    日本物理学会 第67回会 年次大会  ( 関西学院大学 西宮上ケ原キャンパス Japan ) 2012.3

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    Type:Competition, symposium, etc. 

  • その他

    •第117回日本物理学会九州支部例会  2011.12

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    Type:Competition, symposium, etc. 

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Research Projects

  • 細胞質中の非熱揺らぎの実態とその有用性の情報熱力学解析

    Grant number:22H04848  2022 - 2023

    日本学術振興会・文部科学省  科学研究費助成事業  新学術領域研究

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    Authorship:Principal investigator  Grant type:Scientific research funding

  • 細胞質中の非熱揺らぎの実態とその有用性の情報熱力学解析

    2022 - 2023

    科学研究費補助金 (文部科学省)

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    Authorship:Principal investigator  Grant type:Contract research

  • 非熱揺らぎの時空間スペクトル解析に基づく細胞質の非平衡挙動の解明

    Grant number:21H01048  2021 - 2023

    日本学術振興会  科学研究費助成事業  基盤研究(B)

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    Authorship:Principal investigator  Grant type:Scientific research funding

  • 非熱揺らぎの時空間スペクトル解析に基づく細胞質の非平衡挙動の解明

    2021 - 2023

    科学研究費補助金 (文部科学省)

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    Grant type:Contract research

  • 非平衡系のガラス・ジャミング転移

    2020 - 2023

    日本学術振興会  科学研究費助成事業  基盤研究(A)

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    Authorship:Coinvestigator(s)  Grant type:Scientific research funding

  • 揺動散逸定理の破れと非ガウス性解析に基づく非熱的揺らぎの有用性評価

    Grant number:20H05536  2020 - 2021

    日本学術振興会・文部科学省  科学研究費助成事業  新学術領域研究

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    Authorship:Principal investigator  Grant type:Scientific research funding

  • 揺動散逸定理の破れと非ガウス性解析に基づく非熱的揺らぎの有用性評価

    Grant number:20H05536  2020 - 2021

    日本学術振興会  科学研究費助成事業  基盤研究(B)

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    Authorship:Principal investigator  Grant type:Scientific research funding

  • フィードバックと補償光学を用いた細胞内粒子の光捕捉操作とレーザー干渉計測

    2019

    新分野創成センター先端光科学研究分野 プロジェクト

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    Authorship:Principal investigator  Grant type:Contract research

  • 代謝依存的にガラス形成する細胞質のマイクロレオロジー

    Grant number:18H01189  2018 - 2020

    日本学術振興会  科学研究費助成事業  基盤研究(B)

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    Authorship:Principal investigator  Grant type:Scientific research funding

  • 補償光学を用いた生体組織の力学計測

    2018

    新分野創成センター先端光科学研究分野 プロジェクト

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    Authorship:Principal investigator  Grant type:Contract research

  • ”活きの良さ”に基づく幹細胞分化と癌悪性化の非平衡力学研究

    2017

    QRプログラム ワカバチャレンジ

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    Authorship:Principal investigator  Grant type:On-campus funds, funds, etc.

  • アクティブなゆらぎ環境下での生体分子モーターキネシンの1分子運動解析

    Grant number:15K05248  2015 - 2018

    日本学術振興会  科学研究費助成事業  基盤研究(C)

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    Grant type:Scientific research funding

  • 「ゆらぎと構造の協奏:非平衡系における普遍法則の確立」のための国際活動支援

    Grant number:15K21724  2015 - 2017

    日本学術振興会・文部科学省  科学研究費助成事業  新学術領域研究

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    Grant type:Scientific research funding

  • フィードバックマイクロレオロジーによる細胞力学の観測

    Grant number:15H03710  2015 - 2017

    日本学術振興会  科学研究費助成事業  基盤研究(C)

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    Grant type:Scientific research funding

  • フィードバックマイクロレオロジーによる細胞力学の観測

    Grant number:15H03710  2015 - 2017

    日本学術振興会  科学研究費助成事業  基盤研究(B)

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    Authorship:Principal investigator  Grant type:Scientific research funding

  • 力と力学特性による細胞競合メカニズム

    Grant number:15H01494  2015 - 2016

    日本学術振興会・文部科学省  科学研究費助成事業  新学術領域研究

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    Authorship:Principal investigator  Grant type:Scientific research funding

  • 力と力学特性による細胞競合メカニズム

    Grant number:15H01494  2015 - 2016

    日本学術振興会・文部科学省  科学研究費助成事業  新学術領域研究

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    Authorship:Principal investigator  Grant type:Scientific research funding

  • 非熱的に駆動されたバイオマターの非平衡動力学

    Grant number:25103011  2013 - 2017

    日本学術振興会・文部科学省  科学研究費助成事業  新学術領域研究

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    Grant type:Scientific research funding

  • 細胞集団が形成する組織の非線形・非平衡メカニクスと自発生成力の観測

    Grant number:25127712  2013 - 2014

    日本学術振興会  科学研究費助成事業  基盤研究(C)

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    Grant type:Scientific research funding

  • 細胞集団が形成する組織の非線形・非平衡メカニクスと自発生成力の観測

    Grant number:25127712  2013 - 2014

    日本学術振興会・文部科学省  科学研究費助成事業  新学術領域研究

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    Authorship:Principal investigator  Grant type:Scientific research funding

  • 多粒子光トラップによる神経細胞の軸索伸長の制御とその特異性の起源の解明

    Grant number:24657105  2012 - 2014

    科学研究費助成事業  挑戦的萌芽研究

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    Authorship:Principal investigator  Grant type:Scientific research funding

  • 多粒子光トラップによる神経細胞の軸索伸長の制御とその特異性の起源の解明

    Grant number:24657105  2012 - 2013

    日本学術振興会  科学研究費助成事業  基盤研究(C)

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    Grant type:Scientific research funding

  • 細胞内部の非平衡力学に基づく非熱的揺動力の計測

    Grant number:23684036  2011 - 2012

    日本学術振興会  科学研究費助成事業  基盤研究(C)

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    Grant type:Scientific research funding

  • 生体ソフトマターの非平衡力学計測

    Grant number:21015024  2009 - 2010

    日本学術振興会  科学研究費助成事業  基盤研究(C)

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    Grant type:Scientific research funding

  • 生きものの力学物性を支配する非平衡統計力学

    Grant number:20684018  2008 - 2010

    日本学術振興会  科学研究費助成事業  基盤研究(C)

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    Grant type:Scientific research funding

  • 細胞内応力分布の高分解能計測による細胞の非平衡動力学の解明

    Grant number:19840040  2007 - 2008

    日本学術振興会  科学研究費助成事業  基盤研究(C)

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    Grant type:Scientific research funding

  • 複雑流体中における生体1分子の動的機能計測と、そのマイクロフローシステムへの応用

    Grant number:03J10486  2003 - 2004

    日本学術振興会  科学研究費助成事業  基盤研究(C)

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    Grant type:Scientific research funding

  • 単一粒子計測による3次元プローブ顕微鏡の開発

    Grant number:01J05349  2001 - 2002

    日本学術振興会  科学研究費助成事業  基盤研究(C)

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    Grant type:Scientific research funding

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Class subject

  • 生物物理学B

    2024.12 - 2025.2   Winter quarter

  • 生物物理学(R2以前入学者用)

    2024.10 - 2025.3   Second semester

  • 生物物理学A

    2024.10 - 2024.12   Fall quarter

  • 電磁気学Ⅰ・同演習

    2024.4 - 2024.9   First semester

  • 力学基礎

    2024.4 - 2024.9   First semester

  • 物理学入門ⅡB

    2023.12 - 2024.2   Winter quarter

  • 生物物理学B

    2023.12 - 2024.2   Winter quarter

  • 物理学特別講義13

    2023.10 - 2024.3   Second semester

  • 生物物理学

    2023.10 - 2024.3   Second semester

  • 物理学入門Ⅱ(R2以前入学者用)

    2023.10 - 2024.3   Second semester

  • 物理学入門ⅡA

    2023.10 - 2023.12   Fall quarter

  • 生物物理学A

    2023.10 - 2023.12   Fall quarter

  • 力学基礎

    2023.4 - 2023.9   First semester

  • 電磁気学Ⅰ・同演習

    2023.4 - 2023.9   First semester

  • 生物物理学

    2022.10 - 2023.3   Second semester

  • 電磁気学Ⅰ・同演習

    2022.4 - 2022.9   First semester

  • 力学基礎

    2022.4 - 2022.9   First semester

  • 生物物理学

    2021.10 - 2022.3   Second semester

  • 物理学実験

    2021.10 - 2022.3   Second semester

  • 物理学実験

    2021.4 - 2021.9   First semester

  • 電磁気学Ⅰ・同演習

    2021.4 - 2021.9   First semester

  • 生物物理学

    2020.10 - 2021.3   Second semester

  • 物理学特別講義16

    2020.10 - 2021.3   Second semester

  • 生物物理学

    2020.10 - 2021.3   Second semester

  • 物理学特別講義16

    2020.10 - 2021.3   Second semester

  • 基幹物理学Ⅱ

    2020.4 - 2020.9   First semester

  • 基幹物理学Ⅱ

    2020.4 - 2020.9   First semester

  • 生物物理学

    2019.10 - 2020.3   Second semester

  • 物理学実験

    2019.10 - 2020.3   Second semester

  • 生物物理学

    2019.10 - 2020.3   Second semester

  • 基幹物理学Ⅱ

    2019.4 - 2019.9   First semester

  • 基幹物理学Ⅱ

    2019.4 - 2019.9   First semester

  • 物理学実験

    2019.4 - 2019.9   First semester

  • 生物物理学(物理学特別講義C)

    2018.10 - 2019.3   Second semester

  • 物理学実験

    2018.10 - 2019.3   Second semester

  • 基幹物理学Ⅱ

    2018.4 - 2018.9   First semester

  • 物理学実験

    2018.4 - 2018.9   First semester

  • 生物物理学(物理学特別講義C)

    2017.10 - 2018.3   Second semester

  • 物理学実験

    2017.10 - 2018.3   Second semester

  • 身の回りの物理学B

    2017.6 - 2017.8   Summer quarter

  • 基幹物理学Ⅱ

    2017.4 - 2017.9   First semester

  • 物理学実験

    2017.4 - 2017.9   First semester

  • 身の回りの物理学

    2016.10 - 2017.3   Second semester

  • 生物物理学(物理学特別講義C)

    2016.10 - 2017.3   Second semester

  • 基礎物理学実験

    2016.10 - 2017.3   Second semester

  • 身の回りの物理学

    2016.4 - 2016.9   First semester

  • 身の回りの物理学

    2016.4 - 2016.9   First semester

  • 身の回りの物理学

    2015.10 - 2016.3   Second semester

  • 物理学ゼミナール

    2015.10 - 2016.3   Second semester

  • 身の回りの物理学

    2015.4 - 2015.9   First semester

  • 物理学概論B

    2014.10 - 2015.3   Second semester

  • 身の回りの物理学

    2014.10 - 2015.3   Second semester

  • 熱と波動論基礎

    2014.4 - 2014.9   First semester

  • 身の回りの物理学

    2014.4 - 2014.9   First semester

  • 熱と波動論基礎

    2013.4 - 2013.9   First semester

  • 物理コアⅠ

    2013.4 - 2013.9   First semester

  • 物理学ゼミナール

    2012.10 - 2013.3   Second semester

  • 熱と波動論基礎

    2012.4 - 2012.9   First semester

  • 物理コアⅠ

    2012.4 - 2012.9   First semester

  • 物理学ゼミナール

    2011.10 - 2012.3   Second semester

  • 熱と波動論基礎

    2011.10 - 2012.3   Second semester

  • 物理コアⅠ

    2011.4 - 2011.9   First semester

  • 熱と波動論基礎

    2010.10 - 2011.3   Second semester

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FD Participation

  • 2023.3   Role:Participation   Title:【物理学科FD】物理数学の教育と効果的な演習に向けて

    Organizer:Undergraduate school department

  • 2023.3   Role:Participation   Title:【物理学科FD】物理数学の教育と効果的な演習に向けて

    Organizer:Undergraduate school department

  • 2022.3   Role:Participation   Title:【物理学科FD】ティーチング・フェロー制度の概要と講義での活用に向けて

    Organizer:Undergraduate school department

  • 2022.3   Role:Participation   Title:【物理学科FD】ティーチング・フェロー制度の概要と講義での活用に向けて

    Organizer:Undergraduate school department

  • 2019.7   Role:Participation   Title:3ポリシーに関する全学FD ~日本学術会議分野別参照基準に基づく理学部物理学科の3ポリシー~

    Organizer:University-wide

  • 2019.7   Role:Participation   Title:3ポリシーに関する全学FD ~日本学術会議分野別参照基準に基づく理学部物理学科の3ポリシー~

    Organizer:University-wide

  • 2015.1   Role:Planning   Title:改定GPA制度にともなう成績評価のあり方、および、標準化について

    Organizer:Undergraduate school department

  • 2014.1   Role:Planning   Title:「大学院教育のあり方について」

    Organizer:Undergraduate school department

  • 2012.12   Role:Participation   Title:Physics Education at POSTECH

    Organizer:[Undergraduate school/graduate school/graduate faculty]

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Outline of Social Contribution and International Cooperation activities

  • 九州大学理学研究院、および、 サンカルロス大学理学部等との国際連携活動を主導 (研修生受け入れ、留学生受け入れ、部局間交流)

Social Activities

  • 相分離 メカニズムと疾患 第4章 解析技術 1. 「液滴混み合い状態としての細胞内レオロジー」

    羊土社  2021.6

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    Audience: General, Scientific, Company, Civic organization, Governmental agency

  • 生体の科学 2021年 06月号 特集 生物物理学の進歩——生命現象の定量的理解へ向けて ■Ⅰ.分子レベル 「生きている細胞の非平衡力学」」

    医学書院  2021.6

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    Audience: General, Scientific, Company, Civic organization, Governmental agency

  • 九州大学物理学科 体験入学・公開講座

    九州大学物理学科  2018.3

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    Audience: General, Scientific, Company, Civic organization, Governmental agency

    Type:Lecture

Media Coverage

  • 若手研究者紹介 Newspaper, magazine

    2011.9

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    若手研究者紹介

Educational Activities for Highly-Specialized Professionals in Other Countries

  • 2013.4 - 2013.8   ENS de Cachanに在学する修士課程学生Benjamin Brunelを約半年間受け入れて、研修・指導を行った。

    Main countries of student/trainee affiliation:France

Acceptance of Foreign Researchers, etc.

  • Goettingen University

    Acceptance period: 2015.4   (Period):Less than 2 weeks

    Nationality:Germany

  • Vrije University Amsterdam

    Acceptance period: 2015.3 - 2015.7  

    Nationality:Japan

  • Acceptance period: 2014.12 - 2015.5   (Period):1 month or more

    Nationality:Philippines

    Business entity:Other

  • University of San Carlos

    Acceptance period: 2014.12 - 2015.2  

    Nationality:Philippines

  • Acceptance period: 2014.12 - 2015.2   (Period):1 month or more

    Nationality:Philippines

    Business entity:Other

  • Acceptance period: 2014.4   (Period):2weeks to less than 1 month

    Nationality:Philippines

    Business entity:On-campus funds

  • IPBS/CNRS

    Acceptance period: 2014.3 - 2014.4   (Period):2weeks to less than 1 month

    Nationality:France

    Business entity:On-campus funds

  • Vrije University

    Acceptance period: 2014.2 - 2015.3   (Period):1 month or more

    Nationality:Netherlands

    Business entity:Other

  • 九州大学

    Acceptance period: 2013.5   (Period):1 month or more

    Nationality:China

  • IPBS/CNRS

    Acceptance period: 2012.4 - 2012.5   (Period):2weeks to less than 1 month

    Nationality:France

    Business entity:Japan Society for the Promotion of Science

  • Acceptance period: 2012.3 - 2012.8   (Period):1 month or more

    Nationality:Japan

    Business entity:Japan Society for the Promotion of Science

  • IPBS/CNRS

    Acceptance period: 2011.8   (Period):2weeks to less than 1 month

    Nationality:France

    Business entity:Japan Society for the Promotion of Science

  • Acceptance period: 2010.4 - 2012.12   (Period):1 month or more

    Nationality:Japan

▼display all

Travel Abroad

  • 2007.6 - 2007.7

    Staying countory name 1:Germany   Staying institution name 1:Goettingen University

  • 2003.4 - 2006.12

    Staying countory name 1:Netherlands   Staying institution name 1:Vrije Universiteit Amsterdam