Updated on 2024/11/12

Information

 

写真a

 
TARAMA MITSUSUKE
 
Organization
Faculty of Science Department of Physics Assistant Professor
School of Sciences Department of Physics(Concurrent)
Graduate School of Sciences Department of Physics(Concurrent)
Title
Assistant Professor

Research Areas

  • Natural Science / Biophysics, chemical physics and soft matter physics

Degree

  • Master of Science

  • Doctor of Science

Research History

  • RIKEN Center for Biosystems Dynamics Research  Research Scientist 

    2022.4 - 2022.8

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  • RIKEN RIKEN Center for Biosystems Dynamics Research Special Postdoctoral Researcher 

    2019.4 - 2022.3

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  • 理化学研究所 生命機能科学研究センター   

    理化学研究所 生命機能科学研究センター

  • 京都大学 福井謙一記念研究センター   

Education

  • Kyoto University   Faculty of Science  

    - 2010.3

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Research Interests・Research Keywords

  • Research theme: physics of biological phenomena

    Keyword: cell migration, cytoskeleton dynamics

    Research period: 2015.4 - 2022.9

  • Research theme: active matter physics

    Keyword: active matter

    Research period: 2010.4 - 2022.9

Awards

  • ポスター発表賞

    2019.11   第9回ソフトマター研究会  

  • ポスター発表賞

    2019.11   第9回ソフトマター研究会  

  • Presentation Awards for Young Scientist

    2018.11   the International Conference on Advances in Physics of Emergent orders in Fluctuations  

  • Presentation Awards for Young Scientists

    2018.11   International Conference on Advances in Physics of Emergent orders in Fluctuations (APEF2018)   Presentation Awards for Young Scientists

  • the Richard M. Noyes Fund Fellowship

    2014.7   the Gordon Research Conference on Oscillations & Dynamic Instabilities in Chemical Systems  

  • Richard M. Noyes Fund Fellowship

    2014.7   Gordon Research Conference on Oscillations & Dynamic Instabilities in Chemical Systems  

  • ポスター発表 優秀賞

    2012.8   平成24年度未踏科学サマー道場  

  • ポスター発表優秀賞

    2012.8   平成24年度未踏科学サマー道場  

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Papers

  • Emergence of periodic circumferential actin cables from the anisotropic fusion of actin nanoclusters during tubulogenesis Reviewed

    Sayaka Sekine, Mitsusuke Tarama, Housei Wada, Mustafa M. Sami, Tatsuo Shibata, Shigeo Hayashi

    Nature Communications   15 ( 1 )   464   2024.1   eISSN:2041-1723

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    Language:Others   Publishing type:Research paper (scientific journal)   Publisher:Springer Science and Business Media LLC  

    Abstract

    The periodic circumferential cytoskeleton supports various tubular tissues. Radial expansion of the tube lumen causes anisotropic tensile stress, which can be exploited as a geometric cue. However, the molecular machinery linking anisotropy to robust circumferential patterning is poorly understood. Here, we aim to reveal the emergent process of circumferential actin cable formation in a Drosophila tracheal tube. During luminal expansion, sporadic actin nanoclusters emerge and exhibit circumferentially biased motion and fusion. RNAi screening reveals the formin family protein, DAAM, as an essential component responding to tissue anisotropy, and non-muscle myosin II as a component required for nanocluster fusion. An agent-based model simulation suggests that crosslinkers play a crucial role in nanocluster formation and cluster-to-cable transition occurs in response to mechanical anisotropy. Altogether, we propose that an actin nanocluster is an organizational unit that responds to stress in the cortical membrane and builds a higher-order cable structure.

    DOI: 10.1038/s41467-023-44684-z

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    Other Link: https://www.nature.com/articles/s41467-023-44684-z

  • Epithelial cell chirality emerges through the dynamic concentric pattern of actomyosin cytoskeleton

    Takaki Yamamoto, Tomoki Ishibashi, Yuko Mimori-Kiyosue, Sylvain Hiver, Naoko Tokushige, Mitsusuke Tarama, Masatoshi Takeichi, Tatsuo Shibata

    2023.8

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    Language:Others  

    DOI: 10.1101/2023.08.16.553476

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  • Mechanochemical Subcellular-Element Model for Force- and Torque-Free Cell Crawling

    TARAMA Mitsusuke, YAMAMOTO Ryoichi

    Seibutsu Butsuri   63 ( 6 )   306 - 309   2023   ISSN:05824052 eISSN:13474219

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    Language:Japanese   Publisher:The Biophysical Society of Japan General Incorporated Association  

    <p>細胞遊走は発生や恒常性の維持などの生命現象において本質的な重要性を持つ.一方,細胞の生み出す力の総和はゼロとなる.このフォースフリーの条件のもとで細胞内の化学濃度伝搬波がどのように細胞の空間的な運動に変換されるのかを,細胞内化学反応と細胞力学を組み合わせた数理モデルを用いて解析した研究を紹介する.</p>

    DOI: 10.2142/biophys.63.306

    CiNii Research

  • Mechanochemical subcellular-element model of crawling cells Reviewed

    Tarama, M., Mori, K., Yamamoto, R.

    Frontiers in Cell and Developmental Biology   10   1046053   2022.12   ISSN:2296-634X

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:Frontiers in Cell and Developmental Biology  

    Constructing physical models of living cells and tissues is an extremely challenging task because of the high complexities of both intra- and intercellular processes. In addition, the force that a single cell generates vanishes in total due to the law of action and reaction. The typical mechanics of cell crawling involve periodic changes in the cell shape and in the adhesion characteristics of the cell to the substrate. However, the basic physical mechanisms by which a single cell coordinates these processes cooperatively to achieve autonomous migration are not yet well understood. To obtain a clearer grasp of how the intracellular force is converted to directional motion, we develop a basic mechanochemical model of a crawling cell based on subcellular elements with the focus on the dependence of the protrusion and contraction as well as the adhesion and de-adhesion processes on intracellular biochemical signals. By introducing reaction-diffusion equations that reproduce traveling waves of local chemical concentrations, we clarify that the chemical dependence of the cell-substrate adhesion dynamics determines the crawling direction and distance with one chemical wave. Finally, we also perform multipole analysis of the traction force to compare it with the experimental results. Our present work sheds light on how intracellular chemical reactions are converted to a directional cell migration under the force-free condition. Although the detailed mechanisms of actual cells are far more complicated than our simple model, we believe that this mechanochemical model is a good prototype for more realistic models.

    DOI: 10.3389/fcell.2022.1046053

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  • Pattern formation and the mechanics of a motor-driven filamentous system confined by rigid membranes Reviewed International journal

    Mitsusuke Tarama, Tatsuo Shibata

    Physical Review Research 4, 043071   4 ( 4 )   2022.10   ISSN:26431564 eISSN:2643-1564

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:American Physical Society (APS)  

    Pattern formation and the mechanics of a mixture of actin filaments and myosin motors that is confined by a rigid membrane is investigated. By using a coarse-grained molecular dynamics model, we demonstrate that the competition between the depletion force and the active force of the motors gives rise to actin accumulation in the membrane vicinity. The resulting actomyosin structure exerts pressure on the membrane that, due to nematic alignment of the filaments, converges to a constant for large motor active force. The results are independent of filament length and membrane curvature, indicating the universality of this phenomenon. Thus, this paper proposes a mechanism by which the compounds of the cytoskeleton can self-organize into a higher-order structure.

    DOI: 10.1103/PhysRevResearch.4.043071

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    Other Link: https://journals.aps.org/prresearch/abstract/10.1103/PhysRevResearch.4.043071

  • Chapter 12. Nonlinear Dynamics of Active Deformable Particles

    Mitsusuke Tarama

    2018.11

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    Language:English  

    DOI: 10.1039/9781788013499-00284

  • Mechanics of cell crawling by means of force-free cyclic motion Reviewed International journal

    M. Tarama and R. Yamamoto

    J. Phys. Soc. Jpn. 87, 044803 (2018).   2018.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: https://doi.org/10.7566/JPSJ.87.044803

    Other Link: https://journals.jps.jp/doi/10.7566/JPSJ.87.044803

  • Dynamics of Deformable Active Particles under External Flow Field Invited Reviewed

    Mitsusuke Tarama

    JOURNAL OF THE PHYSICAL SOCIETY OF JAPAN   86 ( 10 )   101011   2017.10

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    In most practical situations, active particles are affected by their environment, for example, by a chemical concentration gradient, light intensity, gravity, or confinement. In particular, the effect of an external flow field is important for particles swimming in a solvent fluid. For deformable active particles such as self-propelled liquid droplets and active vesicles, as well as microorganisms such as euglenas and neutrophils, a general description has been developed by focusing on shape deformation. In this review, we present our recent studies concerning the dynamics of a single active deformable particle under an external flow field. First, a set of model equations of active deformable particles including the effect of a general external flow is introduced. Then, the dynamics under two specific flow profiles is discussed: a linear shear flow, as the simplest example, and a swirl flow. In the latter case, the scattering dynamics of the active deformable particles by the swirl flow is also considered.

    DOI: 10.7566/JPSJ.86.101011

  • Swinging motion of active deformable particles in Poiseuille flow Reviewed International journal

    M. Tarama

    Phys. Rev. E 96, 022602 (2017).   2017.8

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    DOI: https://doi.org/10.1103/PhysRevE.96.022602

    Other Link: https://journals.aps.org/pre/abstract/10.1103/PhysRevE.96.022602

  • Swinging motion of active deformable particles in Poiseuille flow Reviewed

    Mitsusuke Tarama

    PHYSICAL REVIEW E   96 ( 2 )   022602   2017.8

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    Dynamics of active deformable particles in an external Poiseuille flow is investigated. To make the analysis general, we employ time-evolution equations derived from symmetry considerations that take into account an elliptical shape deformation. First, we clarify the relation of our model to that of rigid active particles. Then, we study the dynamical modes that active deformable particles exhibit by changing the strength of the external flow. We emphasize the difference between the active particles that tend to self-propel parallel to the elliptical shape deformation and those self-propelling perpendicularly. In particular, a swinging motion around the centerline far from the channel walls is discussed in detail.

    DOI: 10.1103/PhysRevE.96.022602

  • Dynamics of Deformable Active Particles under External Flow Field Invited Reviewed International journal

    Mitsusuke Tarama

    J. Phys. Soc. Jpn. 86, 101011 (2017).   2017.8

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    DOI: https://doi.org/10.7566/JPSJ.86.101011

    Other Link: https://journals.jps.jp/doi/10.7566/JPSJ.86.101011

  • Reciprocating motion of active deformable particles Reviewed International journal

    M. Tarama and T. Ohta

    Europhys. Lett. 114, 30002 (2016).   2016.5

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    DOI: https://doi.org/10.1209/0295-5075/114/30002

    Other Link: https://iopscience.iop.org/article/10.1209/0295-5075/114/30002

  • Reciprocating motion of active deformable particles Reviewed

    M. Tarama, T. Ohta

    EPL   114 ( 3 )   30002   2016.5

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    Language:English   Publishing type:Research paper (scientific journal)  

    Reciprocating motion of an active deformable particle in a homogeneous medium is studied theoretically. For generality, we employ a simple model derived from symmetry considerations for the center-of-mass velocity and elliptical and triangular deformations in two dimensions. We carry out, for the first time, a systematic investigation of the reciprocating motion of a self-propelled particle. It is clarified that spontaneous breaking of the front-rear asymmetry is essential for the reciprocating motion. Moreover, two routes are found for the formation of the reciprocating motion. One is a bifurcation from a motionless stationary state. The other is destabilisation of an oscillatory rectilinear motion. Copyright (C) EPLA, 2016

    DOI: 10.1209/0295-5075/114/30002

  • Simple model of cell crawling Reviewed International journal

    T. Ohta, M. Tarama, and M. Sano

    Physica D 318-319, 3-11 (2016).   2016.4

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    DOI: https://doi.org/10.1016/j.physd.2015.10.007

    Other Link: https://www.sciencedirect.com/science/article/abs/pii/S0167278915001967?via%3Dihub

  • Simple model of cell crawling Reviewed

    T. Ohta, M. Tarama, M. Sano

    PHYSICA D-NONLINEAR PHENOMENA   318   3 - 11   2016.4

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    Based on symmetry consideration of migration and shape deformations, we formulate phenomenologically the dynamics of cell crawling in two dimensions. Forces are introduced to change the cell shape. The shape deformations induce migration of the cell on a substrate. For time-independent forces we show that not only a stationary motion but also a limit cycle oscillation of the migration, velocity and the shape occurs as a result of nonlinear coupling between different deformation modes. Time-dependent forces are generated in a stochastic manner by utilizing the so-called coherence resonance of an excitable system. The present coarse-grained model has a flexibility that it can be applied, e.g., both to keratocyte cells and to Dictyostelium cells, which exhibit quite different dynamics from each other. The key factors for the motile behavior inherent in each cell type are identified in our model. (C) 2015 Elsevier B.V. All rights reserved.

    DOI: 10.1016/j.physd.2015.10.007

  • Dynamics of a deformable self-propelled particle with internal rotational force (vol 2013, 013A01, 2013)

    Mitsusuke Tarama, Takao Ohta

    PROGRESS OF THEORETICAL AND EXPERIMENTAL PHYSICS   ( 2 )   2015.2

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    Language:English  

    DOI: 10.1093/ptep/ptv029

  • Tunable dynamic response of magnetic gels: Impact of structural properties and magnetic fields Reviewed International journal

    M. Tarama, P. Cremer, D.Y. Borin, S. Odenbach H. Löwen, and A.M. Menzel

    Phys. Rev. E 90, 042311 (2014).   2014.10

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    DOI: https://doi.org/10.1103/PhysRevE.90.042311

    Other Link: https://journals.aps.org/pre/abstract/10.1103/PhysRevE.90.042311

  • Tunable dynamic response of magnetic gels: Impact of structural properties and magnetic fields Reviewed

    Mitsusuke Tarama, Peet Cremer, Dmitry Y. Borin, Stefan Odenbach, Hartmut Loewen, Andreas M. Menzel

    PHYSICAL REVIEW E   90 ( 4 )   042311   2014.10

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    Ferrogels and magnetic elastomers feature mechanical properties that can be reversibly tuned from outside through magnetic fields. Here we concentrate on the question of how their dynamic response can be adjusted. The influence of three factors on the dynamic behavior is demonstrated using appropriate minimal models: first, the orientational memory imprinted into one class of the materials during their synthesis; second, the structural arrangement of the magnetic particles in the materials; and third, the strength of an external magnetic field. To illustrate the latter point, structural data are extracted from a real experimental sample and analyzed. Understanding how internal structural properties and external influences impact the dominant dynamical properties helps to design materials that optimize the requested behavior.

    DOI: 10.1103/PhysRevE.90.042311

  • Deformable microswimmer in a swirl: Capturing and scattering dynamics Reviewed

    Mitsusuke Tarama, Andreas M. Menzel, Hartmut Loewen

    PHYSICAL REVIEW E   90 ( 3 )   032907   2014.9

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    Inspired by the classical Kepler and Rutherford problem, we investigate an analogous setup in the context of active microswimmers: the behavior of a deformable microswimmer in a swirl flow. First, we identify new steady bound states in the swirl flow and analyze their stability. Second, we study the dynamics of a self-propelled swimmer heading towards the vortex center, and we observe the subsequent capturing and scattering dynamics. We distinguish between two major types of swimmers, those that tend to elongate perpendicularly to the propulsion direction and those that pursue a parallel elongation. While the first ones can get caught by the swirl, the second ones were always observed to be scattered, which proposes a promising escape strategy. This offers a route to design artificial microswimmers that show the desired behavior in complicated flow fields. It should be straightforward to verify our results in a corresponding quasi-two-dimensional experiment using self-propelled droplets on water surfaces.

    DOI: 10.1103/PhysRevE.90.032907

  • Deformable microswimmer in a swirl: Capturing and scattering dynamics Reviewed International journal

    M. Tarama, A.M. Menzel, and H. Löwen

    Phys. Rev. E 90, 032907 (2014).   2014.9

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    DOI: https://doi.org/10.1103/PhysRevE.90.032907

    Other Link: https://journals.aps.org/pre/abstract/10.1103/PhysRevE.90.032907

  • Individual and collective dynamics of self-propelled soft particles Invited Reviewed International journal

    M. Tarama, Y. Itino, A.M. Menzel, and T. Ohta

    Eur. Phys. J. Special Topics 223, 121–139 (2014).   2014.1

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    DOI: https://doi.org/10.1140/epjst/e2014-02088-y

    Other Link: https://link.springer.com/article/10.1140/epjst/e2014-02088-y

  • Individual and collective dynamics of self-propelled soft particles Invited Reviewed

    M. Tarama, Y. Itino, A. M. Menzel, T. Ohta

    EUROPEAN PHYSICAL JOURNAL-SPECIAL TOPICS   223 ( 1 )   121 - 139   2014.1

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    Deformable self-propelled particles provide us with one of the most important nonlinear dissipative systems, which are related, for example, to the motion of microorganisms. It is emphasized that this is a subject of localized objects in non-equilibrium open systems. We introduce a coupled set of ordinary differential equations to study various dynamics of individual soft particles due to the nonlinear couplings between migration, spinning and deformation. By introducing interactions among the particles, the collective dynamics and its collapse are also investigated by changing the particle density and the interaction strength. We stress that assemblies of self-propelled particles also exhibit a variety of non-equilibrium localized patterns. It is our great pleasure to dedicate the present article to Professor Helmut R. Brand on the occasion of his sixtieth birthday. Professor Brand has made outstanding efforts for the scientific interaction in the field of non-linear and non-equilibrium physics between Japan and Germany for the past thirty years.

    DOI: 10.1140/epjst/e2014-02088-y

  • Dynamics of a deformable active particle under shear flow Reviewed International journal

    M. Tarama, A.M. Menzel, B. ten Hagens, R Wittkowski, T. Ohta, and H. Löwen

    J. Chem. Phys. 139, 104906 (2013).   2013.9

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    DOI: https://doi.org/10.1063/1.4820416

    Other Link: https://aip.scitation.org/doi/10.1063/1.4820416

  • Dynamics of a deformable active particle under shear flow Reviewed

    Mitsusuke Tarama, Andreas M. Menzel, Borge ten Hagen, Raphael Wittkowski, Takao Ohta, Hartmut Loewen

    JOURNAL OF CHEMICAL PHYSICS   139 ( 10 )   104906   2013.9

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    The motion of a deformable active particle in linear shear flow is explored theoretically. Based on symmetry considerations, we propose coupled nonlinear dynamical equations for the particle position, velocity, deformation, and rotation. In our model, both, passive rotations induced by the shear flow as well as active spinning motions, are taken into account. Our equations reduce to known models in the two limits of vanishing shear flow and vanishing particle deformability. For varied shear rate and particle propulsion speed, we solve the equations numerically in two spatial dimensions and obtain a manifold of different dynamical modes including active straight motion, periodic motions, motions on undulated cycloids, winding motions, as well as quasi-periodic and chaotic motions induced at high shear rates. The types of motion are distinguished by different characteristics in the real-space trajectories and in the dynamical behavior of the particle orientation and its deformation. Our predictions can be verified in experiments on self-propelled droplets exposed to a linear shear flow. (C) 2013 AIP Publishing LLC.

    DOI: 10.1063/1.4820416

  • Oscillatory motions of an active deformable particle Reviewed

    Mitsusuke Tarama, Takao Ohta

    Physical Review E - Statistical, Nonlinear, and Soft Matter Physics   87 ( 6 )   062912   2013.6

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    We investigate dynamics of an active particle in which shape deformations occur spontaneously. In two dimensions, the deformations are expanded in terms of the Fourier series and the couplings of different modes are taken into consideration truncated up to lower orders. We focus our attention on the special symmetrical structure between the coupled equations of n- and 2n-mode deformations for n=1, and those for n=2. We show that an oscillatory bifurcation occurs for n=2, which corresponds mathematically to the bifurcation for n=1 where a straight motion becomes unstable and a circular motion appears. At the oscillatory state, the particle undergoes either a spinning motion or a standing oscillation of shape deformations. © 2013 American Physical Society.

    DOI: 10.1103/PhysRevE.87.062912

  • Oscillatory motions of an active deformable particle Reviewed International journal

    M. Tarama and T. Ohta

    Phys. Rev. E 87, 062912 (2013).   2013.6

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    DOI: https://doi.org/10.1103/PhysRevE.87.062912

    Other Link: https://journals.aps.org/pre/abstract/10.1103/PhysRevE.87.062912

  • Dynamics of a deformable self-propelled particle with internal rotational force Reviewed International journal

    M. Tarama and T. Ohta

    Prog. Theor. Exp. Phys. 2013, 013A01 (2013).   2013.1

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    DOI: https://doi.org/10.1093/ptep/pts051

    Other Link: https://academic.oup.com/ptep/article/2013/1/013A01/1563466

  • Dynamics of a deformable self-propelled particle with internal rotational force Reviewed

    Mitsusuke Tarama, Takao Ohta

    PROGRESS OF THEORETICAL AND EXPERIMENTAL PHYSICS   2013 ( 1 )   2013.1

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    We investigate the dynamics of a single deformable active particle that is accompanied by two types of internal force. One is related to the spontaneous propulsion of the center of mass and the other to the spontaneous spinning motion around the center of mass. The equations of motion are derived from the symmetry argument for the velocity of the center of mass, the traceless symmetric tensor variable characterizing the deformation, and the antisymmetric tensor variable for the spinning motion. Numerical simulations are carried out in both two and three dimensions to investigate the dynamics due to the coupling between migration, deformation, and spinning. Some of the bifurcations are studied by an analytical approach.

    DOI: 10.1093/ptep/pts051

  • Spinning motion of a deformable self-propelled particle in two dimensions Reviewed

    Mitsusuke Tarama, Takao Ohta

    JOURNAL OF PHYSICS-CONDENSED MATTER   24 ( 46 )   464129   2012.11

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    We investigate the dynamics of a single deformable self-propelled particle which undergoes a spinning motion in a two-dimensional space. Equations of motion are derived from symmetry arguments for three kinds of variable. One is a vector which represents the velocity of the center of mass. The second is a traceless symmetric tensor representing deformation. The third is an antisymmetric tensor for spinning degree of freedom. By numerical simulations, we have obtained a variety of dynamical states due to interplay between the spinning motion and the deformation. The bifurcations of these dynamical states are analyzed by the simplified equations of motion.

    DOI: 10.1088/0953-8984/24/46/464129

  • Spinning motion of a deformable self-propelled particle in two dimensions Reviewed International journal

    M. Tarama and T. Ohta

    J. Phys.: Condens. Matter 24, 464129 (2012).   2012.10

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    DOI: https://doi.org/10.1088/0953-8984/24/46/464129

    Other Link: https://iopscience.iop.org/article/10.1088/0953-8984/24/46/464129

  • Dynamics of a deformable self-propelled particle under external forcing

    M. Tarama, T. Ohta

    EUROPEAN PHYSICAL JOURNAL B   83 ( 3 )   391 - 400   2011.10

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    We investigate dynamics of a deformable self-propelled particle under external fields in two dimensions based on the time-evolution equations for the center of mass and a tensor variable characterizing deformations. We consider two kinds of external force. One is a gravitational force which enters additively in the time-evolution equation for the center of mass. The other is an electric force supposing that a dipole moment is induced in the particle. This force is added to the equation for the deformation tensor. It is shown that a rich variety of dynamics appears by changing the strength of the forces and the migration velocity of a self-propelled particle. A theoretical analysis is carried out to clarify the dynamics and the bifurcations.

    DOI: 10.1140/epjb/e2011-20307-7

  • Breathing instability versus drift instability in a two-component reaction-diffusion system Reviewed

    Mitsusuke Tarama, Takao Ohta, Len M. Pismen

    PHYSICAL REVIEW E   83 ( 1 )   017201   2011.1

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    We investigate the stability of an excited domain in a two-component reaction-diffusion system in two dimensions and correct the previous results obtained by one of the authors [L. M. Pismen, Patterns and Interfaces in Dissipative Dynamics (Springer, Berlin, 2006); Phys. Rev. Lett. 86, 548 (2001)].

    DOI: 10.1103/PhysRevE.83.017201

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Books

  • Self-organized Motion: Physicochemical Design based on Nonlinear Dynamics

    Mitsusuke Tarama, S. Nakata, V. Pimienta, I. Lagzi, H. Kitahata, N. J. Suematsu

    The Royal Society of Chemistry  2018.11 

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    Language:English  

    Self-organized Motion: Physicochemical Design based on Nonlinear Dynamics

Presentations

  • Dynamics and the mechanics of a motor-driven filamentous system confined by membranes

    Mitsusuke Tarama

    28th International Conference on Statistical Physics, Statphys28  2023.8 

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    Event date: 2023.8

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    Dynamics and the mechanics of a motor-driven filamentous system confined by membranes

  • Pattern formation of actin cytoskeleton around membranes Invited

    Mitsusuke Tarama

    NanoLSI公開セミナー  2023.3 

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    Event date: 2023.3

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    Pattern formation of actin cytoskeleton around membranes

  • Dynamic network structure formation of mesoderm cells in early chick embryo

    Mitsusuke Tarama

    アクティブマター研究会2023  2023.1 

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    Event date: 2023.1

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    Country:Other  

    Dynamic network structure formation of mesoderm cells in early chick embryo

  • アクチン細胞骨格のミクロ相分離と構造転移

    多羅間充輔

    第 10 回ソフトマター研究会  2022.11 

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    Event date: 2022.11

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    Country:Other  

  • 細胞膜と相互作用するアクチン骨格の枯渇相と集積相 Invited

    多羅間充輔

    第 11 回分子モーター討論会  2022.11 

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    Event date: 2022.11

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    Country:Other  

  • Phase separation and self-organized structures of actin cytoskeleton Invited International conference

    Mitsusuke TARAMA

    25th Anniversary Symposium of German-Japanese Joint Research Project on Nonequilibrium Statistical Physics Perspectives for Future Collaboration  2022.10 

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    Event date: 2022.10

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Yukawa Institute for Theoretical Physics, Kyoto University   Country:Japan  

    Other Link: https://www2.yukawa.kyoto-u.ac.jp/~german-japan2022/index.php

  • 並行平板間の自己推進変形粒子の集団運動

    多羅間充輔, 江端宏之

    日本物理学会2022年秋季大会  2022.9 

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    Event date: 2022.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • Microphase separation and transition dynamics of self-organized structures of actin cytoskeleton during tubulogenesis

    Mitsusuke Tarama, Sayaka Sekine, Tatsuo Shibata, Shigeo Hayashi

    第60回日本生物物理学会年会  2022.9 

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    Event date: 2022.9

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    Country:Japan  

  • 初期受精卵における競合する前核のサイズによるヒストンメチル化制御

    多羅間充輔, 京極博久, 柴田達夫, 北島智也

    日本物理学会 2021年秋季大会  2021.9 

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    Epigenetic maintenance controlled by the size of competitive pronuclei in zygotes

  • モーター運動能によるアクチン繊維の皮質構造形成と力生成

    多羅間充輔, 柴田達夫

    日本物理学会 2021年秋季大会  2021.9 

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    Cortical structure formation and force generation of actin filaments driven by motor activity

  • ニワトリ初期胚における中胚葉細胞が自己組織化する動的網目構造

    多羅間充輔, 仲矢由紀子, 柴田達夫

    日本物理学会 2021年秋季大会  2021.9 

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    Dynamic meshwork structure formation of mesoderm cells in early chick embryo

  • In silico study on cytoskeleton structure formation Invited International conference

    Mitsusuke Tarama

    Mathematical Mechanobiology  2021.7 

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    Event date: 2021.7

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  • Cortex structure formation of actomyosin by motor activity

    Mitsusuke Tarama, Tatsuo Shibata

    Active Matter Workshop 2021  2021.1 

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    Event date: 2021.1

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    Cortex structure formation of actomyosin by motor activity

  • Formation of actin cortex structure by myosin motor activity

    Mitsusuke Tarama, Tatsuo Shibata

    第58回 日本生物物理学会 年会  2020.9 

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    Formation of actin cortex structure by myosin motor activity

  • Modeling dynamics around cells Invited

    多羅間充輔

    第1回研究会 「非線形・非平衡系の物理と数理」  2019.8 

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    Event date: 2019.8

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    Modeling dynamics around cells

  • Mechanochemical modeling of crawling cells

    Mitsusuke Tarama, Ryoichi Yamamoto

    Active Matter Workshop 2019  2019.1 

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    Event date: 2019.1

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  • アクティブマターの往復運動への分岐

    多羅間充輔, 太田隆夫, 太田隆夫

    日本物理学会講演概要集(CD-ROM)  2016.3 

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    アクティブマターの往復運動への分岐

  • Appearance of reciprocating motion of active deformable particles

    多羅間充輔

    第3回領域研究会  2016.6 

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  • Reciprocating motion of active deformable particles in homogeneous media International conference

    多羅間充輔

    Statphys26  2016.7 

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    Reciprocating motion of active deformable particles in homogeneous media

  • Back-and-forth motion of active soft particle International conference

    多羅間充輔

    The 4th International Soft Matter Conference  2016.9 

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    Back-and-forth motion of active soft particle

  • Reciprocating motion of active deformable particles International conference

    多羅間充輔

    Patterns in Nature Functions, Variations and Control  2016.10 

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    Reciprocating motion of active deformable particles

  • Back-and-forth motion of active deformable particles International conference

    多羅間充輔

    Microswimmers – From Single Particle Motion to Collective Behaviour  2016.10 

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    Back-and-forth motion of active deformable particles

  • ポアズイユ流中での変形するアクティブマターのダイナミクス

    多羅間充輔

    日本物理学会講演概要集(CD-ROM)  2017.3 

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    ポアズイユ流中での変形するアクティブマターのダイナミクス
    <p>周囲の環境からの外力を受けつつ運動するアクティブマターは興味深い研究対象であり、盛んに研究されている。中でも、流体中を泳動するアクティブマターのダイナミクスを理解する上で周囲の流れ場の影響は無視できない。これまで発表者は流れ場中のアクティブマターのダイナミクスを記述する一般的なモデルを構築した。本発表では、ポアズイユ流れ中での変形するアクティブマターのダイナミクスに関する研究についてお話しする。</p>

  • Nonlinear Dynamics of Active Deformable Particles: From Liquid Droplets to Biological Cells

    多羅間充輔

    第15回 福井センターセミナー  2017.5 

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  • 生物細胞のメカノケミカル・モデル

    多羅間充輔

    札幌非線形現象研究会2017  2017.8 

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  • Mechano-chemical modelling of biological cells

    多羅間充輔

    A02班A03班合同研究会「アクティブマターの概念で繋ぐ生命機能の階層性」 “Hierarchy of biological functions connected by concept of active matter”  2017.9 

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  • 変形する自己推進粒子のポワズイユ流れの中での運動

    多羅間充輔

    生物流体力学における基礎問題と応用問題  2017.10 

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  • ポワズイユ流れ中のアクティブソフトマターのダイナミクス

    多羅間充輔

    第7回ソフトマター研究会  2017.10 

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  • Active Deformable Particles in Poiseuille Flow International conference

    多羅間充輔

    International Symposium on Fluctuation and Structure out of Equilibrium 2017  2017.11 

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    Active Deformable Particles in Poiseuille Flow

  • ポワズイユ流れ中のアクティブソフトマターの運動

    多羅間充輔

    第27回 非線形反応と協同現象研究会  2017.12 

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  • Dynamics of active deformable particles: from swimming droplets to crawling cells International conference

    多羅間充輔

    Structured Soft Interfaces: Caught Between Multi-Scale Simulation and Application  2018.1 

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    Dynamics of active deformable particles: from swimming droplets to crawling cells

  • A minimal model of crawling cells under force-free condition

    多羅間充輔

    Active Matter Workshop 2018  2018.1 

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  • Deformable swimmers in Poiseuille flow

    多羅間充輔

    15th FIFC Symposium  2018.2 

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  • 微生物の力学: 水中での遊泳から基盤上での這行へ

    多羅間充輔

    山口大学 理学部 学術講演会  2018.3 

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  • 基盤上を運動する細胞の力学モデル

    多羅間充輔

    研究会 凝縮系の理論化学  2018.3 

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  • 基盤上を這行する細胞運動の力学メカニズム

    多羅間充輔, 山本量一

    日本物理学会講演概要集(CD-ROM)  2018.3 

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    基盤上を這行する細胞運動の力学メカニズム

  • 基盤上の細胞の這走運動

    多羅間充輔

    京都若手ソフトマター研究会  2018.3 

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  • Mechanics of cell crawling by means of force-free cyclic motion

    多羅間充輔

    BDR SEMINAR in Kobe  2018.5 

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    Mechanics of cell crawling by means of force-free cyclic motion

  • Swinging motion of active deformable particles in Poiseuille flow International conference

    多羅間充輔

    9th International Conference Engineering of Chemical Complexity  2018.6 

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    Swinging motion of active deformable particles in Poiseuille flow

  • Mechanics of cell crawling by means of force-free cyclic motion International conference

    多羅間充輔

    Designer Soft Matter  2018.6 

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    Mechanics of cell crawling by means of force-free cyclic motion

  • Mechanics of cell crawling under force-free condition International conference

    多羅間充輔

    27th International Liquid Crystal Conference (ILCC2018)  2018.7 

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    Mechanics of cell crawling under force-free condition

  • Dynamics of active deformable particles in Poiseuille flow International conference

    多羅間充輔

    10TH LIQUID MATTER CONFERENCE  2018.7 

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    Dynamics of active deformable particles in Poiseuille flow

  • Cell crawling on elastic substrate

    多羅間充輔

    札幌非線形現象研究会2018  2018.8 

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  • Mechanochemical modelling of crawling cells International conference

    Mitsusuke Tarama, Kenji Mori, Ryoichi Yamamoto

    10th International Conference Engineering of Chemical Complexity  2019.6 

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  • 細胞運動のメカノケミカルモデル

    多羅間充輔, 毛利謙司, 山本量一

    日本物理学会 2019年秋季大会  2019.9 

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  • 細胞運動のメカノケミカルモデル

    多羅間充輔

    研究会「理論と実験」2019  2019.10 

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  • 接着性細胞のメカノケミカルモデル

    多羅間充輔、山本量一

    第9回 ソフトマター研究会  2019.11 

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  • アクトミオシン皮質形成の理論研究

    多羅間充輔, 柴田達夫

    第9回 ソフトマター研究会  2019.11 

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  • ミオシンモーターの運動によるアクチン皮質の形成に関する研究

    多羅間充輔, 柴田達夫

    日本物理学会 2020年年次大会  2020.3 

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  • アクティブマターの力生成と変形、自発運動 Invited

    多羅間充輔

    日本液晶学会 ソフトマターフォーラム講演会  2020.10 

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  • 一様空間中における自発的な往復運動の発現

    多羅間充輔

    アクティブマター研究会2016  2016.1 

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  • Breathing instability versus drift instability in a two-component reaction-diffusion system International conference

    多羅間充輔

    Far-From-Equilibrium Dynamics 2011  2011.1 

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    Breathing instability versus drift instability in a two-component reaction-diffusion system

  • 脈動不安定性 vs. 並進不安定性 ~2成分反応拡散系における円形ドメイン解において~

    多羅間充輔

    自然科学縦横無尽2010 理学系異分野交流会  2011.3 

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  • Dynamics of a deformable self-propelled particle under external forcing International conference

    多羅間充輔

    6th International Conference Engineering of Chemical Complexity  2011.7 

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    Dynamics of a deformable self-propelled particle under external forcing

  • 23pGU-10 変形を伴う自己推進粒子の外力下でのダイナミクス(23pGU 反応拡散系・振幅方程式系,領域11(統計力学,物性基礎論,応用数学,力学,流体物理))

    多羅間 充輔, 太田 隆夫

    日本物理学会講演概要集  2011.8 

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    23pGU-10 Dynamics of a deformable self-propelled particle under external forcing

  • 外力下での自己推進粒子の運動

    多羅間充輔

    基研研究会 「非平衡系の物理 -ミクロとマクロの架け橋」  2011.8 

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  • 変形を伴う自己推進粒子の外力下でのダイナミクス

    多羅間充輔, 太田隆夫

    日本物理学会講演概要集  2011.8 

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    変形を伴う自己推進粒子の外力下でのダイナミクス

  • 自己駆動粒子の外力下におけるダイナミクス

    多羅間充輔

    第2回京都若手ソフトマター研究会  2011.11 

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  • Influence of external forcing on the dynamics of a deformable self-propelled particle International conference

    多羅間充輔

    International Symposium on Complex Systems 2011  2011.12 

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    Influence of external forcing on the dynamics of a deformable self-propelled particle

  • Spinning motion of a deformable self-propelled particle in a two-dimensional space International conference

    多羅間充輔

    Phase Transition Dynamics in Soft Matter: Bridging Microscale and Mesoscale  2012.2 

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    Spinning motion of a deformable self-propelled particle in a two-dimensional space

  • Dynamics of a deformable particle driven by internal and external forces International conference

    多羅間充輔

    "Colloidal Dispersions in External Fields" CODEF III  2012.3 

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    Dynamics of a deformable particle driven by internal and external forces

  • やわらかな自発運動粒子の自転運動

    多羅間充輔

    基研研究会2012 「非平衡系の物理 -その普遍的理解を目指して」  2012.8 

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  • やわらかな粒子の自発運動と外力による駆動

    多羅間充輔

    未踏科学サマー道場  2012.8 

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  • Spinning motion of an active soft particle International conference

    多羅間充輔

    Active Dynamics on Microscales: Molecular Motors and Self-Propelling Particles  2012.9 

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    Spinning motion of an active soft particle

  • Active spinning of a deformable self-propelled particle International conference

    多羅間充輔

    Japanese-German-French Workshop “Physics of Active Soft Matter”  2012.9 

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    Active spinning of a deformable self-propelled particle

  • Spontaneous rotation of a deformable self-propelled particle International conference

    多羅間充輔

    17th Fall Seminar on Nonlinear Dynamics in Bayreuth 2012  2012.10 

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    Spontaneous rotation of a deformable self-propelled particle

  • 自発的に動くやわらかな粒子の自転運動

    多羅間充輔

    第22回「非線形反応と協同現象」研究会  2012.12 

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  • Spontaneous spinning motion of an active deformable particle International conference

    多羅間充輔

    Spatio-temporal Organization in Non-equilibrium Systems  2013.2 

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    Spontaneous spinning motion of an active deformable particle

  • Dynamics of an active soft particle with spinning motion International conference

    多羅間充輔

    Self-organization and Emergent Dynamics in Active Soft Matter  2013.2 

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    Dynamics of an active soft particle with spinning motion

  • An active soft particle with a spontaneous spinning motion International conference

    多羅間充輔

    GCOE Symposium Development of emergent new fields  2013.2 

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    An active soft particle with a spontaneous spinning motion

  • 27aXM-4 やわらかな自己推進粒子の自転運動(27aXM 反応拡散系・振動子系,領域11(統計力学,物性基礎論,応用数学,力学,流体物理))

    多羅間 充輔, 太田 隆夫

    日本物理学会講演概要集  2013.3 

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    27aXM-4 Spinning motion of a deformable self-propelled particle

  • アクティブソフトマターの自転運動

    多羅間充輔

    第三回京都若手ソフトマター研究会  2013.3 

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  • やわらかな自己推進粒子の自転運動

    多羅間充輔, 太田隆夫

    日本物理学会講演概要集  2013.3 

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    やわらかな自己推進粒子の自転運動

  • Oscillatory motions of an active deformable particle International conference

    多羅間充輔

    7th International Conference Engineering of Chemical Complexity  2013.6 

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    Oscillatory motions of an active deformable particle

  • 自発的に変形する粒子の自転運動と振動運動

    多羅間充輔

    時間生物学会サテライトシンポジウム 「生物リズム現象の数理フロンティア」  2013.11 

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  • アクティブソフトマターの自転運動について

    多羅間充輔

    第23回「非線形反応と協同現象」研究会  2013.12 

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  • アクティブソフトマターの剪断流中でのダイナミクス

    多羅間充輔

    第3回ソフトマター研究会  2013.12 

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  • やわらかな自発運動粒子系における自転運動について

    多羅間充輔

    第1回領域研究会  2013.12 

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  • 30pAJ-6 流れの中のアクティブソフトマターのモデリングと線形剪断流中でのダイナミクス(30aAJ アクティブマター・その他の系,領域11(物性基礎論・統計力学・流体物理・応用数学・社会経済物理))

    多羅間 充輔, Menzel A. M., Hagen ten, Wittkowski R., 太田 隆夫, Lowen H.

    日本物理学会講演概要集  2014.3 

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    30pAJ-6 Modeling of deformable active particle in flow field and dynamics in linear shear flow

  • 流れの中のアクティブソフトマターのモデリングと線形剪断流中でのダイナミクス

    多羅間充輔, MENZEL A. M, TEN HAGEN B, WITTKOWSKI R, 太田隆夫, LOEWEN H

    日本物理学会講演概要集  2014.3 

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    流れの中のアクティブソフトマターのモデリングと線形剪断流中でのダイナミクス

  • 円形流中の柔らかな自己推進粒子の散乱ダイナミクス

    多羅間充輔

    第4回京都若手ソフトマター研究会  2014.3 

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  • Two types of active spinning motion of deformable particle International conference

    多羅間充輔

    Gordon Research Conference: Oscillations & Dynamic Instabilities in Chemical Systems  2014.7 

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    Two types of active spinning motion of deformable particle

  • Scattering dynamics of active soft particle in swirl International conference

    多羅間充輔

    Gordon Research Seminar: Oscillations & Dynamic Instabilities in Chemical Systems (GRS)  2014.7 

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    Scattering dynamics of active soft particle in swirl

  • Capturing and scattering dynamics of active soft particle in a swirl International conference

    多羅間充輔

    9TH LIQUID MATTER CONFERENCE  2014.7 

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    Capturing and scattering dynamics of active soft particle in a swirl

  • アクティブソフトマターの流れの中でのダイナミクス

    多羅間充輔

    第2回領域研究会  2014.8 

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  • Tunable dynamic response of ferrogels

    多羅間充輔

    第13回 関東ソフトマター研究会  2014.8 

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  • アクティブソフトマターの流れの中での運動

    多羅間充輔

    第24回 非線形反応と協同現象研究会  2014.12 

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  • Nonlinear dynamics of active deformable particles International conference

    多羅間充輔

    Kyoto Winter School for Statistical Mechanics "Frontiers of Statistical Mechanics: From Non-equilibrium Fluctuations to Active Matter",  2015.2 

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    Nonlinear dynamics of active deformable particles

  • Dynamics of active deformable particle in external flow field International conference

    多羅間充輔

    Kyoto Winter School for Statistical Mechanics "Frontiers of Statistical Mechanics: From Non-equilibrium Fluctuations to Active Matter"  2015.2 

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    Dynamics of active deformable particle in external flow field

  • Active deformable particle in an external flow field International conference

    多羅間充輔

    International WE-Heraeus-Physics-School on Model systems for understanding biological processes  2015.2 

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    Active deformable particle in an external flow field

  • アクティブマターにおける変形と運動

    多羅間充輔

    研究会「アクティブ・マター研究の過去・現在・未来」  2015.3 

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    Language:Japanese  

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  • アクティブソフトマターの往復運動

    多羅間充輔

    日本物理学会講演概要集(CD-ROM)  2015.3 

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    アクティブソフトマターの往復運動

  • Tunable dynamic response of magnetic gels: Impact of structural properties and magnetic fields International conference

    多羅間充輔

    Physics of Structural and Dynamical Hierarchy in Soft Matter  2015.3 

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    Tunable dynamic response of magnetic gels: Impact of structural properties and magnetic fields

  • Oscillatory motion of active deformable particles International conference

    多羅間充輔

    8th International Conference Engineering of Chemical Complexity  2015.6 

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    Oscillatory motion of active deformable particles

  • Oscillation of active deformable particles International conference

    多羅間充輔

    International Symposium on Fluctuation and Structure out of Equilibrium 2015 (SFS2015)  2015.8 

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    Oscillation of active deformable particles

  • Reciprocating motion of active deformable particles International conference

    多羅間充輔

    Hierarchical Dynamics in Soft Materials and Biological Matter  2015.9 

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    Reciprocating motion of active deformable particles

  • Active deformable droplet in external flow field

    多羅間充輔

    Workshop on "Aspects of motions in biofluid problems"  2015.10 

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  • アクティブソフトマターの非線形ダイナミクス

    多羅間充輔

    第5回ソフトマター研究会  2015.12 

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    Language:Japanese  

    Country:Other  

  • Oscillatory dynamics of active deformable particles International conference

    多羅間充輔

    Pacifichem 2015  2015.12 

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    Oscillatory dynamics of active deformable particles

  • 気管形成におけるアクチン骨格のミクロ相分離と自己組織化構造の転移ダイナミクス(Microphase separation and transition dynamics of self-organized structures of actin cytoskeleton during tubulogenesis)

    Tarama Mitsusuke, Sekine Sayaka, Shibata Tatsuo, Hayashi Shigeo

    生物物理  2022.8  (一社)日本生物物理学会

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  • 核と細胞質を繋ぐ核膜孔と様々な生命現象 受精卵における核膜孔を介した雌雄前核間の細胞質競合

    京極 博久, 多羅間 充輔, 中川 れい子, 柴田 達夫, 北島 智也

    日本生化学会大会プログラム・講演要旨集  2023.10  (公社)日本生化学会

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    Language:Japanese  

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Professional Memberships

  • The Biophysical Society of Japan

    2022.6 - Present

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  • The Molecular Biology Society of Japan

    2021.8

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  • The Physical Society of Japan

  • The Biophysical Society of Japan

  • The Molecular Biology Society of Japan

  • The Biophysical Society of Japan

  • The Molecular Biology Society of Japan

  • THE PHYSICAL SOCIETY OF JAPAN

  • THE PHYSICAL SOCIETY OF JAPAN

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Academic Activities

  • Screening of academic papers

    Role(s): Peer review

    2024

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    Type:Peer review 

    Number of peer-reviewed articles in foreign language journals:2

  • 企画立案・運営等

    アクティブマター研究会2023  ( Japan ) 2023.1

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    Type:Competition, symposium, etc. 

  • 世話人

    アクティブマター研究会2023  ( Japan ) 2023.1

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    Type:Competition, symposium, etc. 

  • アクティブマター研究会2023

    Role(s): Planning, management, etc.

    2023.1

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    Type:Academic society, research group, etc. 

    researchmap

  • 企画立案・運営等

    第10回ソフトマター研究会  ( Japan ) 2022.11

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    Type:Competition, symposium, etc. 

  • 第10回ソフトマター研究会

    Role(s): Planning, management, etc.

    2022.11

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    Type:Academic society, research group, etc. 

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  • その他

    アクティブマター研究会2022  ( Japan Japan ) 2022.1

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    Type:Competition, symposium, etc. 

  • アクティブマター研究会2022

    ( Japan ) 2022.1

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    Type:Competition, symposium, etc. 

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  • その他

    アクティブマター研究会2021  ( Japan Japan ) 2021.1

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    Type:Competition, symposium, etc. 

  • その他

    アクティブマター研究会2020  ( Japan Japan ) 2020.1

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    Type:Competition, symposium, etc. 

  • その他

    アクティブマター研究会2019  ( Japan Japan ) 2019.1

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    Type:Competition, symposium, etc. 

  • その他

    アクティブマター研究会2018  ( Japan Japan ) 2018.1

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    Type:Competition, symposium, etc. 

  • その他

    アクティブマター研究会2017  ( Japan Japan ) 2017.1

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    Type:Competition, symposium, etc. 

  • その他

    アクティブマター研究会2016  ( Japan Japan ) 2016.1

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    Type:Competition, symposium, etc. 

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Research Projects

  • Mechanochemical Modelling of cell crawling in diorama environment

    Grant number:24H01485  2024.4 - 2026.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Transformative Research Areas (A)

    多羅間 充輔

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    Grant type:Scientific research funding

    細胞運動は発生や恒常性維持などの生命現象に非常に重要な役割を持つ。生体内の力学的な性質は均一ではなく、生化学的要因に加えてこの力学的相互作用により個々の細胞の運動が制御され、組織全体の変形などが適切に実現する。生体内における力学的性質の不均一性を細胞が感知し、運動を応答するプロセスの背後に潜むメカニズムを理解するために、硬さが不均一な基盤により構築されたジオラマ環境における細胞の這走運動を対象にした理論研究を進める。

    CiNii Research

Class subject

  • 統計力学Ⅰ・同演習

    2023.10 - 2024.3   Second semester

  • 力学・同演習

    2023.4 - 2023.9   First semester

  • 統計力学Ⅰ・同演習

    2022.10 - 2023.3   Second semester

  • 統計力学Ⅰ・同演習

    2024.10 - 2025.3   Second semester

  • 物理学特別研究Ⅱ(2年)

    2024.4 - 2025.3   Full year

  • 力学・同演習

    2024.4 - 2024.9   First semester

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FD Participation

  • 2024.2   Role:Participation   Title:【物理学科FD】大学院の魅力創造に向けて

    Organizer:Undergraduate school department

  • 2024.2   Role:Participation   Title:【物理学科FD】大学院の魅力創造に向けて

    Organizer:Undergraduate school department

  • 2023.3   Role:Participation   Title:【物理学科FD】物理数学の教育と効果的な演習に向けて

    Organizer:Undergraduate school department