The effects of blood pressure reduction and of different blood pressure-lowering regimens on major cardiovascular events according to baseline blood pressure: meta-analysis of randomized trials. Reviewed International journal

Czernichow S, Zanchetti A, Turnbull F, Barzi F, Ninomiya T, Kengne AP, Lambers Heerspink HJ, Perkovic V, Huxley R, Arima H, Patel A, Chalmers J, Woodward M, Macmahon S, Neal B; on behalf of the Blood Pressure Lowering Treatment Trialists? Collaboration.

J Hypertens   29   2011.1

Severe hypoglycemia and risks of vascular events and death. Reviewed International journal

Zoungas S, Patel A, Chalmers J, de Galan BE, Li Q, Billot L, Woodward M, Ninomiya T, Neal B, MacMahon S, Grobbee DE, Kengne AP, Marre M, Heller S; ADVANCE Collaborative Group.

N Engl J Med   363   2010.1

Impact of blood pressure lowering on cardiovascular outcomes in normal weight, overweight, and obese individuals: the Perindopril Protection Against Recurrent Stroke Study trial. Reviewed International journal

Czernichow S, Ninomiya T, Huxley R, Kengne AP, Batty GD, Grobbee DE, Woodward M, Neal B, Chalmers J.

Hypertension   55   2010.1

Effects of a fixed combination of perindopril and indapamide in patients with type 2 diabetes and chronic kidney disease. Reviewed International journal

Heerspink HJ, Ninomiya T, Perkovic V, Woodward M, Zoungas S, Cass A, Cooper M, Grobbee DE, Mancia G, Mogensen CE, Neal B, Chalmers J; ADVANCE Collaborative Group.

Eur Heart J   31   2010.1

Aspirin is beneficial in hypertensive patients with chronic kidney disease: a post-hoc subgroup analysis of a randomized controlled trial. Reviewed International journal

Jardine MJ, Ninomiya T, Perkovic V, Cass A, Turnbull F, Gallagher MP, Zoungas S, Lambers Heerspink HJ, Chalmers J, Zanchetti A.

J Am Coll Cardiol   56   2010.1

Intensities of renal replacement therapy in acute kidney injury: a systematic review and meta-analysis. Reviewed International journal

Jun M, Heerspink HJ, Ninomiya T, Gallagher M, Bellomo R, Myburgh J, Finfer S, Palevsky PM, Kellum JA, Perkovic V, Cass A.

Clin J Am Soc Nephrol   5   2010.1

Trends in the prevalence of chronic kidney disease and its risk factors in a general Japanese population: the Hisayama Study. Reviewed International journal

Nagata M, Ninomiya T, Doi Y, Yonemoto K, Kubo M, Hata J, Tsuruya K, Iida M, Kiyohara Y.

Nephrol Dial Transplant   25   2010.1

Association of kidney function with coronary atherosclerosis and calcification in autopsy samples from Japanese elders: the Hisayama study. Reviewed International journal

Nakano T, Ninomiya T, Sumiyoshi S, Fujii H, Doi Y, Hirakata H, Tsuruya K, Iida M, Kiyohara Y, Sueishi K.

Am J Kidney Dis   55   2010.1

Efficacy and safety of routine blood pressure lowering in older patients with diabetes: results from the ADVANCE trial. Reviewed International journal

Ninomiya T, Zoungas S, Neal B, Woodward M, Patel A, Perkovic V, Cass A, Cooper M, Grobbee D, Hamet P, Harrap S, Liu L, Mancia G, Mogensen CE, Poulter N, Rodgers A, Williams B, MacMahon S, Chalmers J; ADVANCE Collaborative Group.

J Hypertens   28   2010.1

Trends in prevalence of Alzheimer's disease and vascular dementia in a Japanese community: the Hisayama Study. Reviewed International journal

Sekita A, Ninomiya T, Tanizaki Y, Doi Y, Hata J, Yonemoto K, Arima H, Sasaki K, Iida M, Iwaki T, Kanba S, Kiyohara Y.

Acta Psychiatr Scand   122   2010.1

Lowering blood pressure reduces renal events in type 2 diabetes. Reviewed International journal

de Galan BE, Perkovic V, Ninomiya T, Pillai A, Patel A, Cass A, Neal B, Poulter N, Harrap S, Mogensen CE, Cooper M, Marre M, Williams B, Hamet P, Mancia G, Woodward M, Glasziou P, Grobbee DE, MacMahon S, Chalmers J; ADVANCE Collaborative Group.

J Am Soc Nephrol   20   2009.1

Proposed criteria for metabolic syndrome in Japanese based on prospective evidence: the Hisayama study. Reviewed International journal

Doi Y, Ninomiya T, Hata J, Yonemoto K, Arima H, Kubo M, Tanizaki Y, Iwase M, Iida M, Kiyohara Y.

Stroke   40   2009.1

Seroprevalence of herpes simplex virus 1 and 2 in a population-based cohort in Japan. Reviewed International journal

Doi Y, Ninomiya T, Hata J, Yonemoto K, Tanizaki Y, Arima H, Liu Y, Rahman M, Iida M, Kiyohara Y.

J Epidemiol   19   2009.1

Risks of cardiovascular events and effects of routine blood pressure lowering among patients with type 2 diabetes and atrial fibrillation: results of the ADVANCE study. Reviewed International journal

Du X, Ninomiya T, de Galan B, Abadir E, Chalmers J, Pillai A, Woodward M, Cooper M, Harrap S, Hamet P, Poulter N, Lip GY, Patel A; ADVANCE Collaborative Group.

Eur Heart J   30   2009.1

Effect of lowering blood pressure on cardiovascular events and mortality in patients on dialysis: a systematic review and meta-analysis of randomised controlled trials. Reviewed International journal

Heerspink HJ, Ninomiya T, Zoungas S, de Zeeuw D, Grobbee DE, Jardine MJ, Gallagher M, Roberts MA, Cass A, Neal B, Perkovic V.

Lancet   373   2009.1

Effects of the end point adjudication process on the results of the Perindopril Protection Against Recurrent Stroke Study (PROGRESS). Reviewed International journal

Ninomiya T, Donnan G, Anderson N, Bladin C, Chambers B, Gordon G, Sharpe N, Chalmers J, Woodward M, Neal B; PROGRESS Collaborative Group.

Stroke   40   2009.1

Proteinuria and stroke: a meta-analysis of cohort studies. Reviewed International journal

Ninomiya T, Perkovic V, Verdon C, Barzi F, Cass A, Gallagher M, Jardine M, Anderson C, Chalmers J, Craig JC, Huxley R.

Am J Kidney Dis   53   2009.1

Albuminuria and kidney function independently predict cardiovascular and renal outcomes in diabetes. Reviewed International journal

Ninomiya T, Perkovic V, de Galan BE, Zoungas S, Pillai A, Jardine M, Patel A, Cass A, Neal B, Poulter N, Mogensen CE, Cooper M, Marre M, Williams B, Hamet P, Mancia G, Woodward M, Macmahon S, Chalmers J; ADVANCE Collaborative Group.

J Am Soc Nephrol   20   2009.1

Intensive glucose control and macrovascular outcomes in type 2 diabetes. Reviewed International journal

Turnbull FM, Abraira C, Anderson RJ, Byington RP, Chalmers JP, Duckworth WC, Evans GW, Gerstein HC, Holman RR, Moritz TE, Neal BC, Ninomiya T, Patel AA, Paul SK, Travert F, Woodward M.

Diabetologia   52   2009.1

Systematic review: sodium bicarbonate treatment regimens for the prevention of contrast-induced nephropathy. Reviewed International journal

Zoungas S, Ninomiya T, Huxley R, Cass A, Jardine M, Gallagher M, Patel A, Vasheghani-Farahani A, Sadigh G, Perkovic V.

Ann Intern Med   151   2009.1

Combined effects of routine blood pressure lowering and intensive glucose control on macrovascular and microvascular outcomes in patients with type 2 diabetes: New results from the ADVANCE trial. Reviewed International journal

Zoungas S, de Galan BE, Ninomiya T, Grobbee D, Hamet P, Heller S, MacMahon S, Marre M, Neal B, Patel A, Woodward M, Chalmers J; ADVANCE Collaborative Group, Cass A, Glasziou P, Harrap S, Lisheng L, Mancia G, Pillai A, Poulter N, Perkovic V, Travert F.

Diabetes Care   32   2009.1

Do men and women respond differently to blood pressure-lowering treatment? Results of prospectively designed overviews of randomized trials. Reviewed International journal

Turnbull F, Woodward M, Neal B, Barzi F, Ninomiya T, Chalmers J, Perkovic V, Li N, MacMahon S; Blood Pressure Lowering Treatment Trialists' Collaboration.

Eur Heart J   29   2008.1

The improvement of renal survival with steroid pulse therapy in IgA nephropathy. Reviewed International journal

Katafuchi R, Ninomiya T, Mizumasa T, Ikeda K, Kumagai H, Nagata M, Hirakata H.

Nephrol Dial Transplant   23   2008.1

Impact of kidney disease and blood pressure on the development of cardiovascular disease: an overview from the Japan Arteriosclerosis Longitudinal Study. Reviewed International journal

Ninomiya T, Kiyohara Y, Tokuda Y, Doi Y, Arima H, Harada A, Ohashi Y, Ueshima H; Japan Arteriosclerosis Longitudinal Study Group.

Circulation   118   2008.1

Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes. Reviewed International journal

Patel A, MacMahon S, Chalmers J, Neal B, Billot L, Woodward M, Marre M, Cooper M, Glasziou P, Grobbee D, Hamet P, Harrap S, Heller S, Liu L, Mancia G, Mogensen CE, Pan C, Poulter N, Rodgers A, Williams B, Bompoint S, de Galan BE, Joshi R, Travert F; ADVANCE Collaborative Group.

N Engl J Med   358   2008.1

The relationship between proteinuria and coronary risk: a systematic review and meta-analysis. Reviewed International journal

Perkovic V, Verdon C, Ninomiya T, Barzi F, Cass A, Patel A, Jardine M, Gallagher M, Turnbull F, Chalmers J, Craig J, Huxley R.

PLoS Med   5   2008.1

Effects of different regimens to lower blood pressure on major cardiovascular events in older and younger adults: meta-analysis of randomised trials. Reviewed International journal

Turnbull F, Neal B, Ninomiya T, Algert C, Arima H, Barzi F, Bulpitt C, Chalmers J, Fagard R, Gleason A, Heritier S, Li N, Perkovic V, Woodward M, MacMahon S; Blood Pressure Lowering Treatment Trialists' Collaboration.

BMJ   336   2008.1

Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus （the ADVANCE trial）: a randomised controlled trial. Reviewed International journal

370   2007.1

A nonsynonymous SNP in PRKCH (protein kinase C eta) increases the risk of cerebral infarction. Reviewed International journal

Kubo M, Hata J, Ninomiya T, Matsuda K, Yonemoto K, Nakano T, Matsushita T, Yamazaki K, Ohnishi Y, Saito S, Kitazono T, Ibayashi S, Sueishi K, Iida M, Nakamura Y, Kiyohara Y.

Nat Genet   39   2007.1

Impact of metabolic syndrome on the development of cardiovascular disease in a general Japanese population: the Hisayama study. Reviewed International journal

Ninomiya T, Kubo M, Doi Y, Yonemoto K, Tanizaki Y, Rahman M, Arima H, Tsuryuya K, Iida M, Kiyohara Y.

Stroke   38   2007.1

Prehypertension increases the risk for renal arteriosclerosis in autopsies: the Hisayama Study. Reviewed International journal

Ninomiya T, Kubo M, Doi Y, Yonemoto K, Tanizaki Y, Tsuruya K, Sueishi K, Tsuneyoshi M, Iida M, Kiyohara Y.

J Am Soc Nephrol   18   2007.1

Metabolic syndrome and CKD in a general Japanese population: the Hisayama Study. Reviewed International journal

Ninomiya T, Kiyohara Y, Kubo M, Yonemoto K, Tanizaki Y, Doi Y, Hirakata H, Iida M.

Am J Kidney Dis   48   2006.1

Decreasing incidence of lacunar vs other types of cerebral infarction in a Japanese population. Reviewed International journal

Kubo M, Kiyohara Y, Ninomiya T, Tanizaki Y, Yonemoto K, Doi Y, Hata J, Shikata K, Iida M.

Neurology   66   2006.1

Chronic kidney disease and cardiovascular disease in a general Japanese population: the Hisayama Study. Reviewed International journal

Ninomiya T, Kiyohara Y, Kubo M, Tanizaki Y, Doi Y, Okubo K, Wakugawa Y, Hata J, Oishi Y, Shikata K, Yonemoto K, Hirakata H, Iida M.

Kidney Int   68 ( 1 )   228 - 236   2005.1

Hyperhomocysteinemia and the development of chronic kidney disease in a general population: the Hisayama study. Reviewed International journal

Ninomiya T, Kiyohara Y, Kubo M, Tanizaki Y, Tanaka K, Okubo K, Nakamura H, Hata J, Oishi Y, Kato I, Hirakata H, Iida M.

Am J Kidney Dis   44 ( 3 )   437 - 445   2004.1

Antioxidant ameliorates cisplatin-induced renal tubular cell death through inhibition of death receptor-mediated pathways. Reviewed International journal

Tsuruya K, Tokumoto M, Ninomiya T, Hirakawa M, Masutani K, Taniguchi M, Fukuda K, Kanai H, Hirakata H, Iida M.

Am J Physiol Renal Physiol   285 ( 2 )   F208 - F218   2003.1

Myeloperoxidase-antineutrophil cytoplasmic antibody-associated glomerulonephritis superimposed on biopsy-proven diabetic nephrosclerosis. Reviewed International journal

Ninomiya T, Kanai H, Hirakawa M, Arimura Y, Masutani K, Kashiwagi M, Nakamura S, Koga Y, Fukuda K, Hirakata H.

Am J Kidney Dis   39 ( 1 )   2002.1

Vgamma1+ gammadelta T cells play protective roles at an early phase of murine cytomegalovirus infection through production of interferon-gamma. Reviewed International journal

Ninomiya T, Takimoto H, Matsuzaki G, Hamano S, Yoshida H, Yoshikai Y, Kimura G, Nomoto K.

Immunology   99 ( 2 )   187 - 194   2000.1

Common protein-altering variant in GFAP is associated with white matter lesions in the older Japanese population. Reviewed

Furuta Y, Akiyama M, Hirabayashi N, Honda T, Shibata M, Ohara T, Hata J, Terao C, Momozawa Y, Tatewaki Y, Taki Y, Nakaji S, Maeda T, Ono K, Mimura M, Nakashima K, Iga JI, Takebayashi M, Ninomiya T; Japan Prospective Studies for Aging and Dementia (JPSC-AD) Study Group

NPJ Genom Med   9   59   2024.11

Novel method for classification of prion diseases by detecting PrPres signal patterns from formalin-fixed paraffin-embedded samples. Reviewed

Koyama S, Yagita K, Hamasaki H, Noguchi H, Shijo M, Matsuzono K, Takase KI, Kai K, Aishima SI, Itoh K, Ninomiya T, Sasagasako N, Honda H

Prion   18   40 - 53   2024.11

Associations between the serum triglyceride level and kidney outcome in patients with chronic kidney disease: the Fukuoka Kidney disease Registry Study. Reviewed

Akiyama M, Tamiya G, Fujiwara K, Shiga Y, Yokoyama Y, Hashimoto K, Sato M, Sato K, Narita A, Hashimoto S, Ueda E, Furuta Y, Hata J, Miyake M, Ikeda HO, Suda K, Numa S, Mori Y, Morino K, Murakami Y, Shimokawa S, Nakamura S, Yawata N, Fujisawa K, Yamana S, Mori K, Ikeda Y, Miyata K, Mori K, Ogino K, Koyanagi Y, Kamatani Y; Biobank Japan Project; Ninomiya T, Sonoda KH, Nakazawa T; Japan Glaucoma Society Omics Group; Genomic Research Committee of the Japanese Ophthalmological Society

Ophthalmology   131   1271 - 1280   2024.11

Behavioral and psychological symptoms and brain volumes in community-dwelling older persons from the Nakayama Study. Reviewed

Tachibana A, Iga JI, Ozaki T, Yoshino Y, Yamazaki K, Ochi S, Kawabe K, Horiuchi F, Yoshida T, Shimizu H, Mori T, Tatewaki Y, Taki Y, Ninomiya T, Ueno SI

Sci Rep   14   26097   2024.10

Skin carotenoid scores and metabolic syndrome in a general Japanese population: the Hisayama Study. Reviewed

Kimura Y, Hata J, Shibata M, Honda T, Sakata S, Furuta Y, Oishi E, Kitazono T, Ninomiya T

Int J Obes (Lond)   48   1465 - 1471   2024.10

Association between hypothalamic Alzheimer's disease pathology and body mass index: the Hisayama Study. Reviewed

Yagita K, Honda H, Ohara T, Koyama S, Noguchi H, Oda Y, Yamasaki R, Isobe N, Ninomiya T

Neuropathology   44   388 - 400   2024.10

Glucose metabolism and smaller hippocampal volume in elderly people with normal cognitive function.

Shima A, Noguchi-Shinohara M, Shibata S, Usui Y, Tatewaki Y, Thyreau B, Hata J, Ohara T, Honda T, Taki Y, Nakaji S, Maeda T, Mimura M, Nakashima K, Iga JI, Takebayashi M, Nishijo H, Ninomiya T, Ono K; Japan Prospective Studies Collaboration for Aging and Dementia (JPSC-AD) study group

NPJ Aging   10   39   2024.9

Vascular calcification Is accelerated by hyponatremia and Low osmolality.

Matsueda S, Yamada S, Torisu K, Kitamura H, Ninomiya T, Nakano T, Kitazono T

Arterioscler Thromb Vasc Biol.   44 ( 9 )   1925 - 1943   2024.9

General and abdominal adiposity and hypertension in eight world regions: a pooled analysis of 837 population-based studies with 7·5 million participants.

NCD Risk Factor Collaboration (NCD-RisC)( Ninomiya T, Hata J)

Lancet   404   851 - 863   2024.8

Association between corneal hysteresis and glaucoma in a Japanese population: the Hisayama Study

Fujiwara K, Ueda E, Hata J, Nakano S, Hashimoto S, Nakamura S, Murakami Y, Kubota T, Yoshitomi T, Ninomiya T, Sonoda KH

Br J Ophthalmol   108   1204 - 1209   2024.8

Association between vascular calcification and Intraplaque hemorrhage in coronary atherosclerosis from autopsy: the Hisayama Study.

Nakano T, Kitamura H, Hata J, Maki K, Oda Y, Kitazono T, Ninomiya T

J Atheroscler Thromb   31   1225 - 1237   2024.8

Association between serum NT-proBNP and gray matter atrophy patterns in an older Japanese population: the Hisayama Study.

J Gerontol A Biol Sci Med Sci   79   glae075   2024.8

Day-to-day home blood pressure variability and risk of atrial fibrillation in a general Japanese population: the Hisayama Study.

Maezono A, Sakata S, Hata J, Oishi E, Furuta Y, Shibata M, Ide T, Kitazono T, Tsutsui H, Ninomiya T

Eur J Prev Cardiol   31   1115 - 1122   2024.7

Risks of dementia in a general Japanese older population with preserved ratio impaired spirometry: the Hisayama Study.

Kawatoko K, Washio Y, Ohara T, Fukuyama S, Honda T, Hata J, Nakazawa T, Kan-O K, Inoue H, Matsumoto K, Nakao T, Kitazono T, Okamoto I, Ninomiya T

J Epidemiol   34   331 - 339   2024.7

Association between retinopathy and risk of dementia in a general Japanese population: the Hisayama Study.

Nakamura S, Ueda E, Ohara T, Hata J, Honda T, Fujiwara K, Furuta Y, Shibata M, Hashimoto S, Nakazawa T, Nakao T, Kitazono T, Sonoda KH, Ninomiya T

Sci Rep   14   12017,   2024.7

Association between masticatory function, frailty, and functional disability: an observational study.

Furuhashi H, Honda T, Furuta Y, Tomooka S, Tajimi T, Kimura Y, Yoshida D, Ninomiya T

BMC Geriatr   24   538   2024.6

Plasma biomarkers for predicting the development of dementia in a community-dwelling older Japanese population.

Ohara T, Tatebe H, Hata J, Honda T, Shibata M, Matsuura S, Mikami T, Maeda T, Ono K, Mimura M, Nakashima K, Iga JI, Takebayashi M, Tokuda T, Ninomiya T; JPSC‐AD (Japan Prospective Studies Collaboration for Aging and Dementia) study group

Psychiatry Clin Neurosci   78   362 - 371   2024.6

Autonomic nervous system function assessed by heart rate variability and the presence of symptoms affecting activities of daily living in community-dwelling residents with chronic pain: the Hisayama Study.

28   831 - 844   2024.5

Serum high-sensitivity C-reactive protein and dementia in a community-dwelling Japanese older population (JPSC-AD).

Tachibana A, Iga JI, Ozaki T, Yoshida T, Yoshino Y, Shimizu H, Mori T, Furuta Y, Shibata M, Ohara T, Hata J, Taki Y, Mikami T, Maeda T, Ono K, Mimura M, Nakashima K, Takebayashi M, Ninomiya T, Ueno SI; JPSC-AD study group

Sci Rep   14   7374   2024.3

Brain atrophy in normal older adult links tooth loss and diet changes to future cognitive decline.

Nakamura H, Noguchi-Shinohara M, Ishimiya-Jokaji M, Kobayashi Y, Isa M, Ide K, Kawano T, Kawashiri S, Uchida K, Tatewaki Y, Taki Y, Ohara T, Ninomiya T, Ono K

NPJ Aging   10   20   2024.3

Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults.

NCD Risk Factor Collaboration (NCD-RisC)( Ninomiya T, Hata J)

Lancet   403   1027 - 1050   2024.3

Longitudinal association of sedentary time with diabetes mellitus and markers of glucose metabolism in middle-aged and older adults: the Hisayama Study. Invited Reviewed International journal

Tsuda S, Honda T, Higashioka M, Hata J, Nakano T, Kitazono T, Ninomiya T

J Diabetes Investig   15   245 - 246   2024.2

Database profile of the Fukuoka-City Information Platform for Community-based Integrated Care. Invited Reviewed International journal

Honda T, Furuhashi H, Furuta Y, Tomooka S, Tajimi T, Nagasawa F, Oishi E, Kimura Y, Yoshida D, Ninomiya T

Annals of Clinical Epidemiology   6   5 - 11   2024.2

Serum lipopolysaccharide-binding protein levels and the incidence of metabolic syndrome in a general Japanese population: the Hisayama Study. Invited Reviewed International journal

Tomooka S, Oishi E, Asada M, Sakata S, Hata J, Chen S, Honda T, Suzuki K, Watanabe H, Murayama N, Wada N, Kitazono T, Ninomiya T

J Epidemiol   1 - 7   2024.1

Role of polyunsaturated fat in modifying cardiovascular risk associated with family history of cardiovascular disease: pooled de novo results from 15 observational studies

Laguzzi F, Åkesson A, Marklund M, Qian F, Gigante B, Bartz TM, Bassett JK, Birukov A, Campos H, Hirakawa Y, Imamura F, Jäger S, Lankinen M, Murphy RA, Senn M, Tanaka T, Tintle N, Virtanen JK, Yamagishi K, Allison M, Brouwer IA, De Faire U, Eiriksdottir G, Ferrucci L, Forouhi NG, Geleijnse JM, Hodge AM, Kimura H, Laakso M, Risérus U, van Westing AC, Bandinelli S, Baylin A, Giles GG, Gudnason V, Iso H, Lemaitre RN, Ninomiya T, Post WS, Psaty BM, Salonen JT, Schulze MB, Tsai MY, Uusitupa M, Wareham NJ, Oh SW, Wood AC, Harris WS, Siscovick D, Mozaffarian D, Leander K; Fatty Acids and Outcomes Research Consortium (FORCE)

Circulation   149   305 - 316   2024.1

Late-Life high blood pressure and enlarged perivascular spaces in the putaminal regions of community-dwelling Japanese older persons.

Tachibana A, Iga JI, Tatewaki Y, Thyreau B, Chen H, Ozaki T, Yoshida T, Yoshino Y, Shimizu H, Mori T, Furuta Y, Shibata M, Ohara T, Hata J, Taki Y, Nakaji S, Maeda T, Ono K, Mimura M, Nakashima K, Takebayashi M, Ninomiya T, Ueno SI; JPSC-AD study group

J Geriatr Psychiatry Neurol   37   61 - 72   2024.1

Global variation in diabetes diagnosis and prevalence based on fasting glucose and hemoglobin A1c. Invited Reviewed International journal

NCD Risk Factor Collaboration (NCD-RisC)(Hata J, Ninomiya T)

Nat Med   29   2885 - 2901   2023.11

Gender and age influence the association between gait speed and mild cognitive impairment in community-dwelling Japanese older adults: from the Japan Prospective Studies Collaboration for Ageing and Dementia (JPSC-AD). Invited Reviewed International journal

Bun S, Suzuki K, Niimura H, Shikimoto R, Kida H, Shibata M, Honda T, Ohara T, Hata J, Nakaji S, Maeda T, Ono K, Nakashima K, Iga JI, Takebayashi M, Ninomiya T, Mimura M; JPSC-AD Study Group

Psychogeriatrics   23   918 - 929   2023.11

n-6 fatty acid biomarkers and incident atrial fibrillation: an individual participant-level pooled analysis of 11 international prospective studies. Invited Reviewed International journal

Garg PK, Guan W, Nomura S, Weir NL, Tintle N, Virtanen JK, Hirakawa Y, Qian F, Sun Q, Rimm E, Lemaitre RN, Jensen PN, Heckbert SR, Imamura F, Steur M, Leander K, Laguzzi F, Voortman T, Ninomiya T, Mozaffarian D, Harris WS, Siscovick DS, Tsai MY; Fatty Aci

Am J Clin Nutr   118   921 - 929   2023.11

Global impact of modifiable risk factors on cardiovascular disease and mortality. Invited Reviewed International journal

Global Cardiovascular Risk Consortium( Sakata S, Ninomiya T)

N Engl J Med   389   1273 - 1285   2023.10

Inadequate care and excessive overprotection during childhood are associated with the presence of diabetes mellitus in adulthood in a general Japanese population: a cross-sectional analysis from the Hisayama Study. Invited Reviewed International journal

Shibata M, Hosoi M, Anno K, Hirabayashi N, Hirakawa Y, Kawata H, Iwaki R, Sawamoto R, Sudo N, Ninomiya T

BMC Endocr Disord   23   222   2023.10

Association between frequency of social contact and brain atrophy in community-dwelling older people without dementia: the JPSC-AD Study. Invited Reviewed International journal

Hirabayashi N, Honda T, Hata J, Furuta Y, Shibata M, Ohara T, Tatewaki Y, Taki Y, Nakaji S, Maeda T, Ono K, Mimura M, Nakashima K, Iga JI, Takebayashi M, Ninomiya T; as the Japan Prospective Studies Collaboration for Aging and Dementia (JPSC-AD) Study

Neurology 101: e1108-e1117, 2023   101   e1108 - e1117   2023.9

Omega-3 fatty acid biomarkers and incident atrial fibrillation. Invited Reviewed International journal

Qian F, Tintle N, Jensen PN, Lemaitre RN, Imamura F, Feldreich TR, Nomura SO, Guan W, Laguzzi F, Kim E, Virtanen JK, Steur M, Bork CS, Hirakawa Y, O'Donoghue ML, Sala-Vila A, Ardisson Korat AV, Sun Q, Rimm EB, Psaty BM, Heckbert SR, Forouhi NG, Wareham NJ

J Am Coll Cardiol   82   336 - 349   2023.7

Association between choroidal thickness and myopic maculopathy in a Japanese population: the Hisayama Study. Invited Reviewed International journal

Ueda E, Yasuda M, Fujiwara K, Hashimoto S, Honda T, Nakamura S, Hata J, Ninomiya T, Sonoda KH

Ophthalmol Sci   3   100350   2023.6

Association of white matter lesions and brain atrophy with the development of dementia in a community: the Hisayama Study. Invited Reviewed International journal

Nakazawa T, Ohara T, Hirabayashi N, Furuta Y, Hata J, Shibata M, Honda T, Kitazono T, Nakao T, Ninomiya T

Psychiatry Clin Neurosci   77   330 - 337   2023.6

Changes in the eicosapentaenoic acid to arachidonic acid ratio in serum over 10 years in a Japanese community: the Hisayama Study. Invited Reviewed International journal

Honda T, Chen S, Hata J, Shibata M, Furuta Y, Oishi E, Sakata S, Kitazono T, Ninomiya T

J Atheroscler Thromb   30   589 - 600   2023.6

Serum Mac-2 binding protein glycosylation isomer concentrations are associated with incidence of type 2 diabetes. Invited Reviewed International journal

Higashioka M, Hirakawa Y, Hata J, Honda T, Sakata S, Shibata M, Kitazono T, Osawa H, Ninomiya T

J Clin Endocrinol Metab   108   e425 - e433   2023.6

Family dysfunction is associated with chronic pain in a community-dwelling Japanese population: the Hisayama Study. Invited Reviewed International journal

Saito T, Shibata M, Hirabayashi N, Honda T, Morisaki Y, Anno K, Sudo N, Hosoi M, Ninomiya T

Eur J Pain   27   518 - 529   2023.4

Sex differences in risk factors for end-stage kidney disease and death in type 2 diabetes: a retrospective cohort study. Invited Reviewed International journal

Oshima M, Iwata Y, Toyama T, Kitajima S, Hara A, Sakai N, Shimizu M, Furuichi K, Haneda M, Babazono T, Yokoyama H, Iseki K, Araki S, Ninomiya T, Hara S, Suzuki Y, Iwano M, Kusano E, Moriya T, Satoh H, Nakamura H, Makino H, Wada T

J Diabetes   15   246 - 254   2023.3

The effect of the Kasuya CKD network on prevention of the progression of chronic kidney disease: successful collaboration of a public health service, primary care physicians and nephrologists-community based cohort study. Invited Reviewed International journal

Katafuchi R, Tanaka S, Matsuo T, Tamai O, Yoshimine K, Yano K, Ueno K, Shimohashi N, Ninomiya T; Kasuya Chronic Kidney Disease Committee

Clin Exp Nephrol   27   32 - 43   2023.3

Association of gait speed with regional brain volumes and risk of dementia in older Japanese: the Hisayama Study. Invited Reviewed International journal

Tajimi T, Furuta Y, Hirabayashi N, Honda T, Hata J, Ohara T, Shibata M, Nakao T, Kitazono T, Nakashima Y, Ninomiya T

Arch Gerontol Geriatr   106   104883   2023.3

Secular trends in the prevalence, incidence, and progression of diabetic retinopathy: the Hisayama Study. Invited Reviewed International journal

Hashimoto S, Yasuda M, Fujiwara K, Ueda E, Nakamura S, Hirakawa Y, Higashioka M, Hata J, Ninomiya T, Sonoda KH

Graefes Arch Clin Exp Ophthalmol   261   641 - 649   2023.3

Diminishing benefits of urban living for children and adolescents' growth and development. Invited Reviewed International journal

NCD Risk Factor Collaboration (NCD-RisC)(Hata J, Ninomiya T)

Nature   615   874 - 883   2023.3

Seasonal variations in renal biopsy numbers and primary glomerular disease features based on the Japan renal biopsy registry. Invited Reviewed International journal

Kanzaki G, Tsuboi N, Yokoo T, Uesugi N, Furuichi K, Shimizu A, Sugiyama H, Sato H, Yokoyama H; Committee for Renal Biopsy and Disease Registry of the Japanese Society of Nephrology (Ninomiya T)

Sci Rep   13   5123   2023.3

Genome-wide association study reveals BET1L associated with survival time in the 137,693 Japanese individuals. Invited Reviewed International journal

Akiyama M, Sakaue S, Takahashi A, Ishigaki K, Hirata M, Matsuda K, Momozawa Y, Okada Y, Ninomiya T; Biobank Japan project; Terao C, Murakami Y, Kubo M, Kamatani Y

Commun Biol   6   143   2023.2

Late-Life High Blood Pressure and Enlarged Perivascular Spaces in the Putaminal Regions of Community-Dwelling Japanese Older Persons Invited Reviewed International journal

Tachibana A, Iga JI, Tatewaki Y, Thyreau B, Chen H, Ozaki T, Yoshida T, Yoshino Y, Shimizu H, Mori T, Furuta Y, Shibata M, Ohara T, Hata J, Taki Y, Nakaji S, Maeda T, Ono K, Mimura M, Nakashima K, Takebayashi M, Ninomiya T, Ueno SI; JPSC-AD study group

J Geriatr Psychiatry Neurol   37   61 - 72   2023.1

Association of omega 3 polyunsaturated fatty acids with incident chronic kidney disease: pooled analysis of 19 cohorts. Invited Reviewed International journal

BMJ   380   2023.1

Long-term trends in the 5-year risk of recurrent stroke over a half century in a Japanese community: the Hisayama Study. Invited Reviewed International journal

Nakanishi Y, Furuta Y, Hata J, Yubi T, Oishi E, Sakata S, Hirakawa Y, Wakisaka Y, Ago T, Kitazono T, Ninomiya T

J Atheroscler Thromb   29   1759 - 1773   2022.12

CKD, brain atrophy, and white matter lesion volume: the Japan prospective studies collaboration for aging and dementia. Invited Reviewed International journal

Maki K, Ohara T, Hata J, Shibata M, Hirabayashi N, Honda T, Sakata S, Furuta Y, Akiyama M, Yamasaki K, Tatewaki Y, Taki Y, Kitazono T, Mikami T, Maeda T, Ono K, Mimura M, Nakashima K, Iga JI, Takebayashi M, Ninomiya T; Japan Prospective Studies Collaborat

Kidney Med   5   100593   2022.12

Mild-to-Moderate kidney dysfunction and cardiovascular disease: observational and mendelian randomization analyses. Invited Reviewed International journal

Circulation 146: 1507-1517, 2022   1507 - 1517   2022.11

Association between chronic low back pain and regional brain atrophy in a Japanese older population: the Hisayama Study. Invited Reviewed International journal

Asada M, Shibata M, Hirabayashi N, Ohara T, Furuta Y, Nakazawa T, Honda T, Hata J, Hosoi M, Sudo N, Yamaura K, Ninomiya T

Pain   163   2185 - 2193   2022.11

Current antihypertensive treatment and treatment-resistant hypertension in Japanese patients with chronic kidney disease. Invited Reviewed International journal

Tsuchimoto A, Tanaka S, Kitamura H, Hiyamuta H, Tsuruya K, Kitazono T, Nakano T; Fukuoka Kidney disease Registry (FKR) study corporation( Ninomiya T, Nagata M)

Clin Exp Nephrol   26   1100 - 1110   2022.11

Prevalence of glaucoma and its systemic risk factors in a general Japanese population: the Hisayama Study. Invited Reviewed International journal

Fujiwara K, Yasuda M, Hata J, Nakano S, Hashimoto S, Ueda E, Nakamura S, Murakami Y, Nakamuro T, Iwase A, Araie M, Tawara A, Kubota T, Yoshitomi T, Ninomiya T, Sonoda KH

Transl Vis Sci Technol   11 ( 11 )   2022.11

Day-to-day blood pressure variability and risk of incident chronic kidney disease in a general Japanese population Invited Reviewed International journal

Sasaki T, Sakata S, Oishi E, Furuta Y, Honda T, Hata J, Tsuboi N, Kitazono T, Yokoo T, Ninomiya T

J Am Heart Assoc   11   e027173   2022.10

Chronological changes in the expression pattern of hippocampal prion proteins during disease progression in sporadic Creutzfeldt-Jakob disease MM1 subtype. Invited Reviewed International journal

Yagita K, Noguchi H, Koyama S, Hamasaki H, Komori T, Aishima S, Kosaka T, Ueda M, Komohara Y, Watanabe A, Sasagasako N, Ninomiya T, Oda Y, Honda H

J Neuropathol Exp Neurol   81   900 - 909   2022.10

Active commuting, commuting modes and the risk of diabetes: 14-year follow-up data from the Hisayama study. Invited Reviewed International journal

Honda T, Hirakawa Y, Hata J, Chen S, Shibata M, Sakata S, Furuta Y, Higashioka M, Oishi E, Kitazono T, Ninomiya T

J Diabetes Investig   13   1677 - 1684   2022.10

Altruistic social activity, depressive symptoms, and brain regional gray matter volume: voxel-based morphometry analysis from 8,695 old adults. Invited Reviewed International journal

Liu Y, Zhang Y, Thyreau B, Tatewaki Y, Matsudaira I, Takano Y, Hirabayashi N, Furuta Y, Hata J, Ninomiya T, Taki Y; Japan Prospective Studies Collaboration for Aging and Dementia (JPSC-AD) Study Group

J Gerontol A Biol Sci Med Sci   77   1789 - 1797   2022.9

Risks of mortality and airflow limitation in Japanese individuals with preserved ratio impaired spirometry. Invited Reviewed International journal

Washio Y, Sakata S, Fukuyama S, Honda T, Kan-o K, Shibata M, Hata J, Inoue H, Kitazono T, Matsumoto K, Ninomiya T

Am J Respir Crit Care Med   206   563 - 572   2022.9

Secular trends in the prevalence of dementia based on a community-based complete enumeration in Japan: the Nakayama Study. Invited Reviewed International journal

Shimizu H, Mori T, Yoshida T, Tachibana A, Ozaki T, Yoshino Y, Ochi S, Sonobe N, Matsumoto T, Komori K, Iga JI, Ninomiya T, Ueno SI, Ikeda M

Psychogeriatrics   22   631 - 641   2022.9

Higher-resolution quantification of white matter hypointensities by large-scale transfer learning from 2D images on the JPSC-AD cohort. Invited Reviewed International journal

Thyreau B, Tatewaki Y, Chen L, Takano Y, Hirabayashi N, Furuta Y, Hata J, Nakaji S, Maeda T, Noguchi-Shinohara M, Mimura M, Nakashima K, Mori T, Takebayashi M, Ninomiya T, Taki Y; Japan Prospective Studies Collaboration for Aging and Dementia (JPSC-AD) St

Hum Brain Mapp   43   3998 - 4012   2022.9

Association of the prefrailty with global brain atrophy and white matter lesions among cognitively unimpaired older adults: the Nakajima study. Invited Reviewed International journal

Noguchi-Shinohara M, Ono K, Yuki-Nozaki S, Iwasa K, Yokogawa M, Komai K, Thyreau B, Tatewaki Y, Taki Y, Shibata M, Ohara T, Hata J, Ninomiya T, Yamada M

Sci Rep   12   12129   2022.8

Association of serum s-adenosylmethionine, s-adenosylhomocysteine, and their ratio with the risk of dementia and death in a community. Invited Reviewed International journal

Mihara A, Ohara T, Hata J, Chen S, Honda T, Tamrakar S, Isa A, Wang D, Shimizu K, Katakura Y, Yonemoto K, Nakao T, Kitazono T, Ninomiya T

Sci Rep   12   12427   2022.7

Association between diabetes and gray matter atrophy patterns in a general older Japanese population: the Hisayama Study. Invited Reviewed International journal

Hirabayashi N, Hata J, Furuta Y, Ohara T, Shibata M, Hirakawa Y, Yamashita F, Yoshihara K, Kitazono T, Sudo N, Ninomiya T

Diabetes Care   45   1364 - 1371   2022.6

Association of inner retinal thickness with prevalent dementia and brain atrophy in a general older population: the Hisayama Study. Invited Reviewed International journal

Ueda E, Hirabayashi N, Ohara T, Hata J, Honda T, Fujiwara K, Furuta Y, Shibata M, Hashimoto S, Nakamura S, Nakazawa T, Nakao T, Kitazono T, Ninomiya T, Sonoda KH

Ophthalmol Sci   100157   2022.4

Baseline periodontal status and modifiable risk factors are associated with tooth loss over a 10-year period: Estimates of population attributable risk in a Japanese community. Invited Reviewed International journal

Furuta M, Takeuchi K, Takeshita T, Shibata Y, Suma S, Kageyama S, Asakawa M, Shimazaki Y, Hata J, Ninomiya T, Yamashita Y

J Periodontol   93   526 - 536   2022.4

Association of daily sleep duration with the incident dementia by serum soluble TREM2 in a community. Invited Reviewed International journal

Ohara T, Hata J, Tanaka M, Honda T, Yamakage H, Inoue T, Hirakawa Y, Kusakabe T, Shibata M, Kitazono T, Nakao T, Satoh-Asahara N, Ninomiya T

J Am Geriatr Soc   70   1147 - 1156   2022.4

Yogurt product intake and reduction of tooth loss risk in a Japanese community. Invited Reviewed International journal

Ma J, Furuta M, Uchida K, Takeshita T, Kageyama S, Asakawa M, Takeuchi K, Suma S, Sakata S, Hata J, Sohn W, Ninomiya T, Yamashita Y

J Clin Periodontol   49   345 - 352   2022.4

Development and validation of a risk prediction model for atherosclerotic cardiovascular disease in Japanese adults: the Hisayama Study Invited Reviewed International journal

Honda T, Chen S, Hata J, Yoshida D, Hirakawa Y, Furuta Y, Shibata M, Sakata S, Kitazono T, Ninomiya T

J Atheroscler Thromb   29   345 - 361   2022.3

Long-term association of vegetable and fruit intake with risk of dementia in Japanese older adults: the Hisayama Study. Invited Reviewed International journal

Kimura Y, Yoshida D, Ohara T, Hata J, Honda T, Hirakawa Y, Shibata M, Oishi E, Sakata S, Furuta Y, Chen S, Uchida K, Nakao T, Kitazono T, Ninomiya T

BMC Geriatr   22   257 - 257   2022.3

Multiple-region grey matter atrophy as a predictor for the development of dementia in a community: the Hisayama Study. Invited Reviewed International journal

Nakazawa T, Ohara T, Hirabayashi N, Furuta Y, Hata J, Shibata M, Honda T, Kitazono T, Nakao T, Ninomiya T

J Neurol Neurosurg Psychiatry 93: 263-271, 2022   93   263 - 271   2022.3

Serum uric acid levels and nephrosclerosis in a population-based autopsy study: the Hisayama Study. Invited Reviewed International journal

Maki K, Hata J, Sakata S, Oishi E, Furuta Y, Nakano T, Oda Y, Kitazono T, Ninomiya T

Am J Nephrol   53   69 - 77   2022.2

Diabetes mellitus, elevated hemoglobin A1c, and glycated albumin are associated with the presence of all-cause dementia and alzheimer's disease: the JPSC-AD Study. Invited Reviewed International journal

Noguchi-Shinohara M, Yuki-Nozaki S, Abe C, Mori A, Horimoto M, Yokogawa M, Ishida N, Suga Y, Ishizaki J, Ishimiya M, Nakamura H, Komai K, Nakamura H, Shibata M, Ohara T, Hata J, Ninomiya T, Yamada M; Japan Prospective Studies Collaboration for Aging and D

J Alzheimers Dis   85   235 - 247   2022.2

Changes in body weight and concurrent changes in cardiovascular risk profiles in community residents in Japan: the Hisayama Study. Invited Reviewed International journal

Honda T, Ishida Y, Oda M, Noguchi K, Chen S, Sakata S, Oishi E, Furuta Y, Yoshida D, Hirakawa Y, Hata J, Kitazono T, Ninomiya T

J Atheroscler Thromb   29   252 - 267   2022.2

A Comparative Study of Site-Specific Distribution of Aging-Related tau astrogliopathy and its risk factors between alzheimer disease and cognitive healthy brains: the Hisayama Study. Invited Reviewed International journal

Yagita K, Honda H, Ohara T, Hamasaki H, Koyama S, Noguchi H, Mihara A, Nakazawa T, Hata J, Ninomiya T, Iwaki T

J Neuropathol Exp Neurol   81   106 - 116   2022.1

Prevalence of chronic kidney disease in Asia: a systematic review and analysis. Invited Reviewed International journal

Liyanage T, Toyama T, Hockham C, Ninomiya T, Perkovic V, Woodward M, Fukagawa M, Matsushita K, Praditpornsilpa K, Hooi LS, Iseki K, Lin MY, Stirnadel-Farrant HA, Jha V, Jun M

BMJ Glob Health   7   e007525   2022.1

Concurrent cardiac transthyretin and brain β amyloid accumulation among the older adults: the Hisayama Study. Invited Reviewed International journal

32   e13014   2022.1

MUTYH actively contributes to microglial activation and impaired neurogenesis in the pathogenesis of alzheimer's disease. Invited Reviewed International journal

Mizuno Y, Abolhassani N, Mazzei G, Sakumi K, Saito T, Saido TC, Ninomiya T, Iwaki T, Yamasaki R, Kira JI, Nakabeppu Y

Oxid Med Cell Longev   8635088   2021.12

Prediction of lifetime risk of cardiovascular disease deaths stratified by sex in the Japanese population. Invited Reviewed International journal

Imai Y, Mizuno Tanaka S, Satoh M, Hirata T, Murakami Y, Miura K, Waki T, Hirata A, Sairenchi T, Irie F, Sata M, Ninomiya T, Ohkubo T, Ishikawa S, Miyamoto Y, Ohnishi H, Saitoh S, Tamakoshi A, Yamada M, Kiyama M, Iso H, Sakata K, Nakagawa H, Okayama A, Ues

J Am Heart Assoc 10: e021753, 2021   10   e021753   2021.12

Risk Classification for Metabolic Syndrome and the Incidence of cardiovascular disease in Japan with low prevalence of obesity: a pooled analysis of 10 prospective cohort studies. Invited Reviewed International journal

Iso H, Cui R, Takamoto I, Kiyama M, Saito I, Okamura T, Miyamoto Y, Higashiyama A, Kiyohara Y, Ninomiya T, Yamada M, Nakagawa H, Sakurai M, Shimabukuro M, Higa M, Shimamoto K, Saito S, Daimon M, Kayama T, Noda M, Ito S, Yokote K, Ito C, Nakao K, Yamauchi

J Am Heart Assoc   10   e020760   2021.12

Pathological review of cardiac amyloidosis using autopsy cases in a single Japanese institution. Invited Reviewed International journal

Tateishi Y, Yamada Y, Katsuki M, Nagata T, Yamamoto H, Kohashi K, Koga Y, Hashisako M, Kiyozawa D, Mori T, Kuboyama Y, Kakinokizono A, Miyazaki Y, Yamaguchi A, Tsutsui H, Ninomiya T, Naiki H, Oda Y

Pathol Res Pract   227   153635   2021.11

Emotional loneliness is associated with a risk of dementia in a general Japanese older population: the Hisayama Study. Invited Reviewed International journal

Shibata M, Ohara T, Hosoi M, Hata J, Yoshida D, Hirabayashi N, Morisaki Y, Nakazawa T, Mihara A, Nagata T, Oishi E, Anno K, Sudo N, Ninomiya T

J Gerontol B Psychol Sci Soc Sci   76   1756 - 1766   2021.10

Midlife and late-life diabetes and sarcopenia in a general older Japanese population: the Hisayama Study. Invited Reviewed International journal

Nakamura K, Yoshida D, Honda T, Hata J, Shibata M, Hirakawa Y, Furuta Y, Kishimoto H, Ohara T, Chen S, Kitazono T, Nakashima Y, Ninomiya T

J Diabetes Investig   12   1899 - 1907   2021.10

Pathologic diabetic nephropathy in autopsied diabetic cases with normoalbuminuria from a Japanese community-based study. Invited Reviewed International journal

Sasaki T, Nakagawa K, Hata J, Hirakawa Y, Shibata M, Nakano T, Tsuboi N, Oda Y, Kitazono T, Yokoo T, Ninomiya T

Kidney Int Rep   6   3035 - 3044   2021.9

Development of a risk prediction model for incident hypertension in Japanese individuals: the Hisayama Study. Invited Reviewed International journal

Oishi E, Hata J, Honda T, Sakata S, Chen S, Hirakawa Y, Yoshida D, Shibata M, Ohara T, Furuta Y, Kitazono T, Ninomiya T

Hypertens Res   44   1221 - 1229   2021.9

Serum NT-proBNP levels and histopathological myocardial fibrosis in autopsied cases from a Japanese community: the Hisayama Study. Invited Reviewed International journal

Sasaki T, Izumaru K, Hata J, Sakata S, Oishi E, Nagata T, Tsuboi N, Oda Y, Kitazono T, Yokoo T, Ninomiya T

J Cardiol   78   237 - 243   2021.9

Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants. Invited Reviewed International journal

NCD Risk Factor Collaboration (NCD-RisC)( Ninomiya T, Hata J)

Lancet   398   957 - 980   2021.9

the Committee for Renal Biopsy and Disease Registry of the Clinical and histological features in pediatric and adolescent/young adult patients with renal disease: a cross-sectional analysis of the Japan Renal Biopsy Registry (J-RBR). Invited Reviewed International journal

Urushihara M, Sato H, Shimizu A, Sugiyama H, Yokoyama H, Hataya H, Matsuoka K, Okamoto T, Ogino D, Miura K, Hamada R, Hibino S, Shima Y, Yamamura T, Kitamoto K, Ishihara M, Konomoto T, Hattori M;

Clin Exp Nephrol   25   1018 - 1026   2021.9

10-year trend of tooth loss and associated factors in a Japanese population-based longitudinal study. Reviewed International journal

Furuta M, Takeuchi K, Takeshita T, Shibata Y, Suma S, Kageyama S, Asakawa M, Hata J, Yoshida D, Shimazaki Y, Ninomiya T, Yamashita Y

BMJ Open   11   2021.8

Comparison of the contributions of impaired beta cell function and insulin resistance to the development of type 2 diabetes in a Japanese community: the Hisayama Study. Invited Reviewed International journal

Yoshinari M, Hirakawa Y, Hata J, Higashioka M, Honda T, Yoshida D, Mukai N, Nakamura U, Kitazono T, Ninomiya T

Diabetologia   64   1775 - 1784   2021.8

Association between socioeconomic status and physical inactivity in a general Japanese population: NIPPON DATA2010. Invited Reviewed International journal

Sumimoto Y, Yanagita M, Miyamatsu N, Okuda N, Nishi N, Nakamura Y, Nakamura K, Miyagawa N, Miyachi M, Kadota A, Ohkubo T, Okamura T, Ueshima H, Okayama A, Miura K; for NIPPON DATA2010 Research Group( Kiyohara Y, Ninomiya T)

PLoS One   16   e0254706   2021.7

Serum high-sensitivity C-reactive protein Levels and the development of atrial fibrillation in a general Japanese population - the Hisayama Study. Invited Reviewed International journal

Yoshikawa T, Hata J, Sakata S, Nagata T, Hirakawa Y, Hirooka Y, Tsutsui H, Kitazono T, Ninomiya T

Circ J   85   1365 - 1372   2021.7

Risk prediction model for incident atrial fibrillation in a general Japanese population - the Hisayama Study. Invited Reviewed International journal

Hata J, Nagata T, Sakata S, Oishi E, Furuta Y, Hirakawa Y, Honda T, Yoshida D, Kitazono T, Ninomiya T

Circ J   85   1373 - 1382   2021.7

Development of a dementia prediction model for primary care: the Hisayama Study. Invited Reviewed International journal

Honda T, Ohara T, Yoshida D, Shibata M, Ishida Y, Furuta Y, Oishi E, Hirakawa Y, Sakata S, Hata J, Nakao T, Ninomiya T

Alzheimers Dement (Amst)   13   e12221   2021.7

Combined changes in albuminuria and kidney function and subsequent risk for kidney failure in type 2 diabetes. Invited Reviewed International journal

Oshima M, Toyama T, Hara A, Shimizu M, Kitajima S, Iwata Y, Sakai N, Furuichi K, Haneda M, Babazono T, Yokoyama H, Iseki K, Araki SI, Ninomiya T, Hara S, Suzuki Y, Iwano M, Kusano E, Moriya T, Satoh H, Nakamura H, Makino H, Wada T

BMJ Open Diabetes Res Care   9   2021.6

N-ｔerminal pro-B-type natriuretic peptide and incident CKD. Invited Reviewed International journal

6   976 - 985   2021.6

Cohort Profile: The Ganka-Ekigaku Network (GEN), a network of Japanese ophthalmological epidemiology studies. Invited Reviewed International journal

Sasaki M, Miyake M, Fujiwara K, Nanba H, Akiyama M, Yanagi Y, Harada S, Tabara Y, Yasuda M, Yamashita H, Kayama T, Tsubota K, Matsuda F, Hashimoto S, Ueda E, Ninomiya T, Takebayashi T, Tsujikawa A, Sonoda KH, Kawasaki R

Ophthalmic Epidemiol   237 - 243   2021.6

Qian F, Ardisson Korat AV, Imamura F, Marklund M, Tintle N, Virtanen JK, Zhou X, Bassett JK, Lai H, Hirakawa Y, Chien KL, Wood AC, Lankinen M, Murphy RA, Samieri C, Pertiwi K, de Mello VD, Guan W, Forouhi NG, Wareham N, Hu ICFB, Riserus U, Lind L, Harris Invited Reviewed International journal

n-3 fatty acid biomarkers and incident type 2 diabetes: an individual participant-level pooling project of 20 prospective cohort studies.

Diabetes Care   44   1133 - 1142   2021.5

Prevalence and mortality of sarcopenia in a community-dwelling older Japanese population: the Hisayama Study. Invited Reviewed International journal

Nakamura K, Yoshida D, Honda T, Hata J, Shibata M, Hirakawa Y, Furuta Y, Kishimoto H, Ohara T, Kitazono T, Nakashima Y, Ninomiya T

J Epidemiol   31   320 - 327   2021.5

Airflow limitation and tongue microbiota in community-dwelling elderly individuals. Invited Reviewed International journal

Takeshita T, Matsumoto K, Furuta M, Fukuyama S, Takeuchi K, Ogata H, Asakawa M, Kageyama S, Hata J, Ninomiya T, Inoue H, Yamashita Y

ERJ Open Res   7   2021.5

Current status of the certification of long-term care insurance among individuals with dementia in a Japanese community: the Hisayama Study. Invited Reviewed International journal

Ohara T, Yoshida D, Hata J, Shibata M, Honda T, Furuta Y, Hirabayashi N, Kitazono T, Nakao T, Ninomiya T

Psychiatry Clin Neurosci   75   182 - 184   2021.5

Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies. Invited Reviewed International journal

Nat Commun   12   2329   2021.4

Urinary N-terminal pro-B-type natriuretic peptide as a biomarker for cardiovascular events in a general Japanese population: the Hisayama Study. Invited Reviewed International journal

Yamasaki K, Hata J, Ide T, Nagata T, Sakata S, Yoshida D, Honda T, Hirakawa Y, Nakano T, Kitazono T, Tsutsui H, Ninomiya T

Environ Health Prev Med   26   47   2021.4

Dietary fiber intake and risk of type 2 diabetes in a general Japanese population: the Hisayama Study. Invited Reviewed International journal

Kimura Y, Yoshida D, Hirakawa Y, Hata J, Honda T, Shibata M, Sakata S, Uchida K, Kitazono T, Ninomiya T

J Diabetes Investig   12   527 - 536   2021.4

Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries. Invited Reviewed International journal

Nat Commun   12   1258   2021.3

Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight. Invited Reviewed International journal

NCD Risk Factor Collaboration (NCD-RisC)(Ninomiya T, Hata J)

Elife   10   2021.3

Risk prediction for new-onset atrial fibrillation using the Minnesota code electrocardiography classification system. Invited Reviewed International journal

Igarashi Y, Nochioka K, Sakata Y, Tamai T, Ohkouchi S, Irokawa T, Ogawa H, Hayashi H, Fujihashi T, Yamanaka S, Shiroto T, Miyata S, Hata J, Yamada S, Ninomiya T, Yasuda S, Kurosawa H, Shimokawa H

Int J Cardiol Heart Vasc   34   2021.3

High serum folate concentrations are associated with decreased risk of mortality among Japanese adults. Invited Reviewed International journal

Chen S, Honda T, Hata J, Sakata S, Furuta Y, Yoshida D, Shibata M, Ohara T, Hirakawa Y, Oishi E, Kitazono T, Ninomiya T

J Nutr   151   657 - 665   2021.3

PCBP2 is downregulated in degenerating neurons and rarely observed in TDP-43-Positive inclusions in sporadic amyotrophic lateral sclerosis. Invited Reviewed International journal

Yoshimura M, Honda H, Sasagasako N, Mori S, Hamasaki H, Suzuki SO, Ishii T, Ninomiya T, Kira JI, Iwaki T

J Neuropathol Exp Neurol   80   220 - 228   2021.2

Randomized trial of an intensified, multifactorial intervention in patients with advanced-stage diabetic kidney disease: Diabetic Nephropathy Remission and Regression Team Trial in Japan (DNETT-Japan). Invited Reviewed International journal

Shikata K, Haneda M, Ninomiya T, Koya D, Suzuki Y, Suzuki D, Ishida H, Akai H, Tomino Y, Uzu T, Nishimura M, Maeda S, Ogawa D, Miyamoto S, Makino H; Diabetic Nephropathy Remission and Regression Team Trial in Japan (DNETT-Japan) collaborative group

J Diabetes Investig   12   207 - 216   2021.2

The association of small dense low-density lipoprotein cholesterol and coronary heart disease in subjects at high cardiovascular risk. Invited Reviewed International journal

Higashioka M, Sakata S, Honda T, Hata J, Shibata M, Yoshida D, Goto K, Kitazono T, Osawa H, Ninomiya T

J Atheroscler Thromb   28   79 - 89   2021.1

Recent status of self-measured home blood pressure in the Japanese general population: a modern database on self-measured home blood pressure (MDAS). Invited Reviewed International journal

Asayama K, Tabara Y, Oishi E, Sakata S, Hisamatsu T, Godai K, Kabayama M, Tatsumi Y, Hata J, Kikuya M, Kamide K, Miura K, Ninomiya T, Ohkubo T

Hypertens Res   43 ( 1403 )   1412   2020.12

Serum N-terminal pro-B-type natriuretic peptide as a predictor for future development of atrial fibrillation in a general population: the Hisayama Study. Invited Reviewed International journal

Nagata T, Hata J, Sakata S, Oishi E, Honda T, Furuta Y, Ohara T, Yoshida D, Hirakawa Y, Shibata M, Ide T, Kitazono T, Tsutsui H, Ninomiya T

Int J Cardiol   320   90 - 96   2020.12

Impact of hypertension stratified by diabetes on the lifetime risk of cardiovascular disease mortality in Japan: a pooled analysis of data from the Evidence for Cardiovascular Prevention from Observational Cohorts in Japan study. Invited Reviewed International journal

Imai Y, Hirata T, Saitoh S, Ninomiya T, Miyamoto Y, Ohnishi H, Murakami Y, Iso H, Tanaka S, Miura K, Tamakoshi A, Yamada M, Kiyama M, Ueshima H, Ishikawa S, Okamura T; Evidence for Cardiovascular Prevention from Observational Cohorts in Japan (EPOCH-JAPAN) Research Group

Hypertens Res   43 ( 1437 )   1444   2020.11

Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants. Invited Reviewed International journal

NCD Risk Factor Collaboration (NCD-RisC)(Ninomiya T, Hata J)

Lancet   396   1511 - 1524   2020.11

Usefulness of the SAGE score to predict elevated values of brachial-ankle pulse wave velocity in Japanese subjects with hypertension. Invited Reviewed International journal

Tomiyama H, Vlachopoulos C, Xaplanteris P, Nakano H, Shiina K, Ishizu T, Kohro T, Higashi Y, Takase B, Suzuki T, Yamazaki T, Furumoto T, Kario K, Inoue T, Koba S, Takemoto Y, Hano T, Sata M, Ishibashi Y, Node K, Tanaka A, Maemura K, Ohya Y, Furukawa T, Ito H, Ohkuma T, Ninomiya T, Chikamori T, Yamashina A, Ueda SI

Hypertens Res   43   1284 - 1292   2020.11

Study design and baseline characteristics of a population-based prospective cohort study of dementia in Japan: the Japan Prospective Studies Collaboration for Aging and Dementia (JPSC-AD). Reviewed International journal

Ninomiya T, Nakaji S, Maeda T, Yamada M, Mimura M, Nakashima K, Mori T, Takebayashi M, Ohara T, Hata J, Kokubo Y, Uchida K, Taki Y, Kumagai S, Yonemoto K, Yoshida H, Muto K, Momozawa Y, Akiyama M, Kubo M, Ikeda M, Kanba S, Kiyohara Y; JPSFC-AD Study Group

Environ Health Prev Med   25   64 - 76   2020.10

Growth differentiation factor 15 and NT-proBNP as blood-based markers of vascular brain injury and dementia. Invited Reviewed International journal

McGrath ER, Himali JJ, Levy D, Conner SC, DeCarli C, Pase MP, Ninomiya T, Ohara T, Courchesne P, Satizabal CL, Vasan RS, Beiser AS, Seshadri S

J Am Heart Assoc   9   2020.10

Influence of the accumulation of unhealthy eating habits on obesity in a general Japanese population: the Hisayama Study. Invited Reviewed International journal

Ishida Y, Yoshida D, Honda T, Hirakawa Y, Shibata M, Sakata S, Furuta Y, Oishi E, Hata J, Kitazozno T, Ninomiya T

Nutrients   12   2020.10

Cohort profile: The Ganka-Ekigaku Network (GEN), a network of Japanese ophthalmological epidemiology studies. Invited Reviewed International journal

Sasaki M, Miyake M, Fujiwara K, Nanba H, Akiyama M, Yanagi Y, Harada S, Tabara Y, Yasuda M, Yamashita H, Kayama T, Tsubota K, Matsuda F, Hashimoto S, Ueda E, Ninomiya T, Takebayashi T, Tsujikawa A, Sonoda KH, Kawasaki R

Ophthalmic Epidemiol   13   1 - 7   2020.8

Five-year incidence of myopic maculopathy in a general Japanese population: the Hisayama Study. Invited Reviewed International journal

Ueda E, Yasuda M, Fujiwara K, Hashimoto S, Ohno-Matsui K, Hata J, Ishibashi T, Ninomiya T, Sonoda KH

JAMA Ophthalmol 3, 2020   138   887 - 893   2020.8

Association between serum glycated albumin and risk of cardiovascular disease in a Japanese community: the Hisayama Study. Invited Reviewed International journal

Mihara A, Ohara T, Hata J, Honda T, Chen S, Sakata S, Oishi E, Hirakawa Y, Nakao T, Kitazono T, Ninomiya T

Atherosclerosis   311   52 - 59   2020.8

Parenting style during childhood is associated with the development of chronic pain and a patient's need for psychosomatic treatment in adulthood: A case-control study. Invited Reviewed International journal

Shibata M, Ninomiya T, Anno K, Kawata H, Iwaki R, Sawamoto R, Kubo C, Kiyohara Y, Sudo N, Hosoi M

Medicine (Baltimore)   99   2020.8

Lifetime cumulative incidence of dementia in a community-dwelling elderly population in Japan. Invited Reviewed International journal

Yoshida D, Ohara T, Hata J, Shibata M, Hirakawa Y, Honda T, Furuta Y, Oishi E, Sakata S, Kanba S, Kitazono T, Ninomiya T

Neurology   95   2020.8

Nephron number and time to remission in steroid-sensitive minimal change disease. Invited Reviewed International journal

Sasaki T, Tsuboi N, Marumoto H, Okabayashi Y, Haruhara K, Kanzaki G, Koike K, Ogura M, Ninomiya T, Yokoo T

Kidney Med   2   559 - 568   2020.8

Small dense low-density lipoprotein cholesterol and the risk of coronary heart disease in a Japanese community. Invited Reviewed International journal

Higashioka M, Sakata S, Honda T, Hata J, Yoshida D, Hirakawa Y, Shibata M, Goto K, Kitazono T, Osawa H, Ninomiya T

J Atheroscler Thromb   27   669 - 682   2020.7

30-minute postload plasma glucose levels during an oral glucose tolerance test predict the risk of future type 2 diabetes: the Hisayama Study Invited Reviewed International journal

Hirakawa Y, Hata J, Yoshinari M, Higashioka M, Yoshida D, Shibata M, Honda T, Sakata S, Kato H, Teramoto T, Maki H, Nishimoto S, Kitazono T, Ninomiya T

BMJ Open Diabetes Res Care   8   2020.7

Elevated serum glycated albumin and glycated albumin : hemoglobin A(1c) ratio were associated with hippocampal atrophy in a general elderly population of Japanese: the Hisayama Study. Invited Reviewed International journal

Ohara T, Furuta Y, Hirabayashi N, Hata J, Hirakawa Y, Honda T, Yoshida D, Shibata M, Kitazono T, Ninomiya T

J Diabetes Investig   11   971 - 979   2020.7

Repositioning of the global epicentre of non-optimal cholesterol. Invited Reviewed International journal

NCD Risk Factor Collaboration (NCD-RisC)(Ninomiya T, Hata J)

Nature   582   73 - 77   2020.6

Serum uric acid levels and cardiovascular mortality in a general Japanese population: the Hisayama Study. Invited Reviewed International journal

Sakata S, Hata J, Honda T, Hirakawa Y, Oishi E, Shibata M, Yoshida D, Goto K, Kitazono T, Ninomiya T

Hypertens Res   43   560 - 568   2020.6

Association of albuminuria with white matter hyperintensities volume on brain magnetic resonance imaging in elderly Japanese - the Hisayama Study. Invited Reviewed International journal

Yamasaki K, Hata J, Furuta Y, Hirabayashi N, Ohara T, Yoshida D, Hirakawa Y, Nakano T, Kitazono T, Ninomiya T

Circ J   84   935 - 942   2020.5

Serum homocysteine and risk of dementia in Japan. Invited Reviewed International journal

Chen S, Honda T, Ohara T, Hata J, Hirakawa Y, Yoshida D, Shibata M, Sakata S, Oishi E, Furuta Y, Kitazono T, Ninomiya T

J Neurol Neurosurg Psychiatry   91   540 - 546   2020.5

Association of anthropometry and weight change with risk of dementia and its major subtypes: A meta-analysis consisting 2.8 million adults with 57 294 cases of dementia. Invited Reviewed International journal

Lee CM, Woodward M, Batty GD, Beiser AS, Bell S, Berr C, Bjertness E, Chalmers J, Clarke R, Dartigues JF, Davis-Plourde K, Debette S, Di Angelantonio E, Feart C, Frikke-Schmidt R, Gregson J, Haan MN, Hassing LB, Hayden KM, Hoevenaar-Blom MP, Kaprio J, Kivimaki M, Lappas G, Larson EB, LeBlanc ES, Lee A, Lui LY, Moll van Charante EP, Ninomiya T, Nordestgaard LT, Ohara T, Ohkuma T, Palviainen T, Peres K, Peters R, Qizilbash N, Richard E, Rosengren A, Seshadri S, Shipley M, Singh-Manoux A, Strand BH, van Gool WA, Vuoksimaa E, Yaffe K, Huxley RR

Obes Rev 21: e12989, 2020   2020.4

睡眠呼吸障害と診断された一般住民の受療行動に影響を及ぼす要因の検討. Invited Reviewed

藤田香奈恵, 宮園真美, 姜　旻廷, 森山宣子, 吉田大悟, 柴田舞欧, 安藤眞一, 二宮利治, 樗木晶子

日循予防誌   55   17 - 28   2020.3

Ratios of serum eicosapentaenoic acid to arachidonic acid and docosahexaenoic acid to arachidonic acid were inversely associated with serum resistin levels: the Hisayama Study. Invited Reviewed International journal

Higashioka M, Hirakawa Y, Kawamura R, Honda T, Hata J, Yoshida D, Takata Y, Kitazono T, Osawa H, Ninomiya T

J Diabetes Investig   11   482 - 489   2020.3

Genome-wide polygenic score and the risk of ischemic stroke in a prospective cohort: the Hisayama Study. Invited Reviewed International journal

Hachiya T, Hata J, Hirakawa Y, Yoshida D, Furuta Y, Kitazono T, Shimizu A, Ninomiya T

Stroke 51: 759-765   51   759 - 765   2020.3

Disrupted tongue microbiota and detection of nonindigenous bacteria on the day of allogeneic hematopoietic stem cell transplantation. Invited Reviewed International journal

Oku S, Takeshita T, Futatsuki T, Kageyama S, Asakawa M, Mori Y, Miyamoto T, Hata J, Ninomiya T, Kashiwazaki H, Yamashita Y

PLoS Pathog   16   2020.3

National trends in total cholesterol obscure heterogeneous changes in HDL and non-HDL cholesterol and total-to-HDL cholesterol ratio: a pooled analysis of 458 population-based studies in Asian and Western countries. Invited Reviewed International journal

NCD Risk Factor Collaboration (NCD-RisC)(Ninomiya T, Hata J)

Int J Epidemiol   49   173 - 192   2020.2

Dietary inflammatory index positively associated with high-sensitivity C-reactive protein level in Japanese from NIPPON DATA2010. Invited Reviewed International journal

Yang Y, Hozawa A, Kogure M, Narita A, Hirata T, Nakamura T, Tsuchiya N, Nakaya N, Ninomiya T, Okuda N, Kadota A, Ohkubo T, Okamura T, Ueshima H, Okayama A, Miura K

J Epidemiol   30   98 - 107   2020.2

Association between blood pressure variability and cerebral small-vessel disease: a systematic review and meta-analysis. Invited Reviewed International journal

J Am Heart Assoc   9   e013841   2020.1

Decline in handgrip strength from midlife to late-life is associated with dementia in a Japanese community: the Hisayama Study. Invited Reviewed International journal

Hatabe Y, Shibata M, Ohara T, Oishi E, Yoshida D, Honda T, Hata J, Kanba S, Kitazono T, Ninomiya T

J Epidemiol   30   15 - 23   2020.1

Brachial-ankle pulse wave velocity versus its stiffness index β-transformed value as risk marker for cardiovascular disease. Invited Reviewed International journal

8   e013004   2019.12

Long-term regular exercise and intraocular pressure: the Hisayama Study. Invited Reviewed International journal

Fujiwara K, Yasuda M, Hata J, Yoshida D, Kishimoto H, Hashimoto S, Yoshitomi T, Ninomiya T, Sonoda KH

Graefes Arch Clin Exp Ophthalmol   257   2461 - 2469   2019.11

Reduced Estimated GFR and Cardiac Remodeling: A Population-Based Autopsy Study. Invited Reviewed International journal

Izumaru K, Hata J, Nakano T, Nakashima Y, Nagata M, Fukuhara M, Oda Y, Kitazono T, Ninomiya T

Am J Kidney Dis.   74 ( 3 )   373 - 381   2019.11

Serum elaidic acid concentration and risk of dementia: the Hisayama Study. Invited Reviewed International journal

Honda T, Ohara T, Shinohara M, Hata J, Toh R, Yoshida D, Shibata M, Ishida T, Hirakawa Y, Irino Y, Sakata S, Uchida K, Kitazono T, Kanba S, Hirata KI, Ninomiya T

Neurology   93   e2053 - e2064   2019.11

Serum lipopolysaccharide-binding protein levels and the incidence of cardiovascular disease in a general Japanese population: the Hisayama Study. Invited Reviewed International journal

Asada M, Oishi E, Sakata S, Hata J, Yoshida D, Honda T, Furuta Y, Shibata M, Suzuki K, Watanabe H, Murayama N, Kitazono T, Yamaura K, Ninomiya T

J Am Heart Assoc   8 ( e013628 )   2019.11

World health organization cardiovascular disease risk charts: revised models to estimate risk in 21 global regions. Invited Reviewed International journal

WHO CVD Risk Chart Working Group (Hisayama: Ninomiya T, Hata J, Hirakawa Y)

Lancet Glob Health   7   e1332 - e1345   2019.10

Association between Axial Length and Myopic Maculopathy: The Hisayama Study. Invited Reviewed International journal

Hashimoto S, Yasuda M, Fujiwara K, Ueda E, Hata J, Hirakawa Y, Ninomiya T, Sonoda KH

Ophthalmol Retina   863 - 873   2019.10

Estimation of nephron number in living humans by combining unenhanced computed tomography with biopsy-based stereology. Invited Reviewed International journal

Sasaki T, Tsuboi N, Okabayashi Y, Haruhara K, Kanzaki G, Koike K, Kobayashi A, Yamamoto I, Takahashi S, Ninomiya T, Shimizu A, Rule AD, Bertram JF, Yokoo T

Sci Rep   9   14400   2019.10

Glucose Tolerance Levels and Circumpapillary Retinal Nerve Fiber Layer Thickness in a General Japanese Population: The Hisayama Study. Invited Reviewed International journal

Fujiwara K, Yasuda M, Hata J, Hirakawa Y, Hashimoto S, Ueda E, Iwase A, Araie M, Yoshitomi T, Ninomiya T, Sonoda KH

Am J Ophthalmol   140 - 146   2019.9

NT-proBNP and risk of dementia in a general Japanese elderly population: the Hisayama Study. Invited Reviewed International journal

Nagata T, Ohara T, Hata J, Sakata S, Furuta Y, Yoshida D, Honda T, Hirakawa Y, Ide T, Kanba S, Kitazono T, Tsutsui H, Ninomiya T

J Am Heart Assoc 8: e011652, 2019   2019.9

Association Between Serum β-Alanine and Risk of Dementia. Invited Reviewed International journal

1637 - 1645   2019.9

Characteristics of the Salivary Microbiota in Patients With Various Digestive Tract Cancers. Invited Reviewed International journal

Kageyama S, Takeshita T, Takeuchi K, Asakawa M, Matsumi R, Furuta M, Shibata Y, Nagai K, Ikebe M, Morita M, Masuda M, Toh Y, Kiyohara Y, Ninomiya T, Yamashita Y

Front Microbiol   1780 - 1789   2019.8

Objectively measured sedentary time and diabetes mellitus in a general Japanese population: The Hisayama Study. Invited Reviewed International journal

Honda T, Kishimoto H, Mukai N, Hata J, Yoshida D, Hirakawa Y, Shibata M, Ohara T, Kumagai S, Ninomiya T

J Diabetes Investig   2019.8

Association Between Genetic Risk and Development of Type 2 Diabetes in a General Japanese Population: The Hisayama Study. Invited Reviewed International journal

Inaishi J, Hirakawa Y, Horikoshi M, Akiyama M, Higashioka M, Yoshinari M, Hata J, Mukai N, Kamatani Y, Momozawa Y, Kubo M, Ninomiya T

J Clin Endocrinol Metab   3213 - 3222   2019.8

Rising rural body-mass index is the main driver of the global obesity epidemic in adults. Invited Reviewed International journal

NCD Risk Factor Collaboration (NCD-RisC)(Hata J, Ninomiya T)

Nature   260 - 264   2019.8

Dietary sodium reduction reduces albuminuria: a cluster randomized trial. Invited Reviewed International journal

Jardine MJ, Li N, Ninomiya T, Feng X, Zhang J, Shi J, Zhang Y, Zhang R, Zhang J, Hao J, Perkovic V, Heerspink HL, Wu Y, Yan LL, Neal B

J Ren Nutr   29   276 - 284   2019.7

Integrated analysis of human genetic association study and mouse transcriptome suggests LBH and SHF genes as novel susceptible genes for amyloid-β accumulation in Alzheimer's disease. Invited Reviewed International journal

137   521 - 533   2019.7

Trends in the prevalence of type 2 diabetes and prediabetes in a Japanese community, 1988–2012: the Hisayama Study. Invited Reviewed International journal

198 - 205   2019.7

Trends in the prevalence of myopia and myopic maculopathy in a Japanese population: the Hisayama Study. Invited Reviewed International journal

Ueda E, Yasuda M, Fujiwara K, Hashimoto S, Ohno-Matsui K, Hata J, Ishibashi T, Ninomiya T, Sonoda KH

Invest Ophthalmol Vis Sci   2781 - 2786   2019.7

Serum ethylamine levels as an indicator of L-theanine consumption and the risk of type 2 diabetes in a general Japanese population: the Hisayama Study. Invited Reviewed International journal

Ninomiya T, Kanzaki N, Hirakawa Y, Yoshinari M, Higashioka M, Honda T, Shibata M, Sakata S, Yoshida D, Teramoto T, Takemoto S, Nishimoto S, Hata J, Kitazono T

Diabetes Care 42: 1234-1240, 2019   1234 - 1240   2019.7

Tauopathy in basal ganglia involvement is exacerbated in a subset of patients with Alzheimer's disease: the Hisayama study. Invited Reviewed International journal

Hamasaki H, Honda H, Suzuki SO, Shijo M, Ohara T, Hatabe Y, Okamoto T, Ninomiya T, Iwaki T

415 - 423   2019.6

Secular trends in the incidence of end-stage renal disease and its risk factors in Japanese patients with immunoglobulin A nephropathy. Invited Reviewed International journal

Tanaka S, Ninomiya T, Katafuchi R, Masutani K, Tsuchimoto A, Tokumoto M, Hirakata H, Ooboshi H, Kitazono T, Tsuruya K

Nephrol Dial Transplant   33   963 - 971   2019.6

Dairy consumption and risk of functional disability in an elderly Japanese population: the Hisayama Study. Invited Reviewed International journal

Yoshida D, Ohara T, Hata J, Shibata M, Hirakawa Y, Honda T, Uchida K, Takasugi S, Kitazono T, Kiyohara Y, Ninomiya T

Am J Clin Nutr   2019.6

Periodontitis is associated with chronic obstructive pulmonary disease. Invited Reviewed International journal

Takeuchi K, Matsumoto K, Furuta M, Fukuyama S, Takeshita T, Ogata H, Suma S, Shibata Y, Shimazaki Y, Hata J, Ninomiya T, Nakanishi Y, Inoue H, Yamashita Y

J Dent Res   98   534 - 540   2019.5

Association of extremely high levels of high-density lipoprotein cholesterol with cardiovascular mortality in a pooled analysis of 9 cohort studies including 43,407 individuals: The EPOCH-JAPAN study. Invited Reviewed International journal

J Clin Lipidol   12   674 - 684   2019.5

Effect of SGLT2 inhibitors on cardiovascular, renal and safety outcomes in patients with type 2 diabetes mellitus and chronic kidney disease: A systematic review and meta-analysis. Invited Reviewed International journal

Toyama T, Neuen BL, Jun M, Ohkuma T, Neal B, Jardine MJ, Heerspink HL, Wong MG, Ninomiya T, Wada T, Perkovic V

Diabetes Obes Metab   1237 - 1250   2019.5

Biomarkers of dietary omega-6 fatty acids and incident cardiovascular disease and mortality. Invited Reviewed International journal

Circulation   139   2422 - 2436   2019.5

Trends in the prevalence of airflow limitation in a general Japanese population: two serial cross-sectional surveys from the Hisayama Study. Invited Reviewed International journal

Ogata H, Hirakawa Y, Matsumoto K, Hata J, Yoshida D, Fukuyama S, Inoue H, Kitazono T, Ninomiya T, Nakanishi Y

BMJ Open   9   e023673   2019.3

Steno-stiffness approach for cardiovascular disease risk assessment in primary prevention. Invited Reviewed International journal

Tomiyama H, Ohkuma T, Ninomiya T, Mastumoto C, Kario K, Hoshide S, Kita Y, Inoguchi T, Maeda Y, Kohara K, Tabara Y, Nakamura M, Ohkubo T, Watada H, Munakata M, Ohishi M, Ito N, Nakamura M, Shoji T, Vlachopoulos C, Aboyans V, Yamashina A; Collaborative Group for J-BAVELs

Hypertension   73   508 - 513   2019.3

Serum magnesium and calcium levels in relation to ischemic stroke: Mendelian randomization study. Invited Reviewed International journal

Neurology   92   e944 - e950   2019.3

Cardiovascular risk factors associated with venous thromboembolism. Invited Reviewed International journal

Emerging Risk Factors Collaboration (Ninomiya T, Doi Y, Kiyohara Y)

JAMA Cardiol   4   163 - 173   2019.2

Ankle-brachial index measured by oscillometry is predictive for cardiovascular disease and premature death in the Japanese population: An individual participant data meta-analysis. Invited Reviewed International journal

Ohkuma T, Ninomiya T, Tomiyama H, Kario K, Hoshide S, Kita Y, Inoguchi T, Maeda Y, Kohara K, Tabara Y, Nakamura M, Ohkubo T, Watada H, Munakata M, Ohishi M, Ito N, Nakamura M, Shoji T, Vlachopoulos C, Aboyans V, Yamashina A; collaborative group for the Japan Brachial-Ankle pulse wave VELocity individual participant data meta-analysis of prospective studies to examine the significance of the Ankle-Brachial Index (J-BAVEL-ABI)

Atherosclerosis   275   141 - 148   2019.2

Longitudinal changes of physical activity and sedentary time in the middle-aged and older Japanese population: the Hisayama Study. Invited Reviewed International journal

Yonemoto K, Honda T, Kishimoto H, Yoshida D, Hata J, Mukai N, Shibata M, Hirakawa Y, Ninomiya T, Kumagai S

J Phys Act Health   16   165 - 171   2019.2

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting. Invited Reviewed International journal

Ganesh Chauhan, et al., Ninomiya T

Neurology   92   e486 - e503   2019.1

Having few remaining teeth is associated with a low nutrient intake and low serum albumin levels in middle-aged and older Japanese individuals: findings from the NIPPON DATA2010. Invited Reviewed International journal

Nakamura M, Ojima T, Nagahata T, Kondo I, Ninomiya T, Yoshita K, Arai Y, Ohkubo T, Murakami K, Nishi N, Murakami Y, Takashima N, Okuda N, Kadota A, Miyagawa N, Kondo K, Okamura T, Ueshima H, Okayama A, Miura K; NIPPON DATA2010 Research Group

Environ Health Prev Med   24   1 - 9   2019.1

Moyamoya disease susceptibility variant RNF213 p.R4810K increases the risk of ischemic stroke attributable to large-artery atherosclerosis. Invited Reviewed International journal

Circulation   139   295 - 298   2019.1

Apparent Treatment-Resistant Hypertension and Cardiovascular Risk in Hemodialysis Patients: Ten-Year Outcomes of the Q-Cohort Study. Invited Reviewed International journal

Tanaka S, Ninomiya T, Hiyamuta H, Taniguchi M, Tokumoto M, Masutani K, Ooboshi H, Nakano T, Tsuruya K, Kitazono

Sci Rep   9   1043 - 1050   2019.1

Serum soluble triggering receptor expressed on myeloid cells 2 as a biomarker for incident dementia: the Hisayama Study. Invited Reviewed International journal

Ohara T, Hata J, Tanaka M, Honda T, Yamakage H, Yoshida D, Inoue T, Hirakawa Y, Kusakabe T, Shibata M, Teraoka T, Kitazono T, Kanba S, Satoh-Asahara N, Ninomiya T

Ann Neurol   85   47 - 58   2019.1

Prevalence of adult epilepsy in a general Japanese population: the Hisayama study. Invited Reviewed International journal

Tanaka A, Hata J, Akamatsu N, Mukai N, Hirakawa Y, Yoshida D, Kishimoto H, Ohara T, Mizuno T, Tsuji S, Kitazono T, Ninomiya T

Epilepsia Open   2019.1

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes. Invited Reviewed International journal

MEGASTROKE Consortium (Ninomiya T, Hata J)

Nat Commun   9   5141   2018.12

Development and validation of modified risk prediction models for cardiovascular disease and its subtypes: the Hisayama Study. Invited Reviewed International journal

Honda T, Yoshida D, Hata J, Hirakawa Y, Ishida Y, Shibata M, Sakata S, Kitazono T, Ninomiya T

Atherosclerosis   279   38 - 44   2018.10

Association between daily sleep duration and risk of dementia and mortality in a Japanese community. Invited Reviewed International journal

Ohara T, Honda T, Hata J, Yoshida D, Mukai N, Hirakawa Y, Shibata M, Kishimoto H, Kitazono T, Kanba S, Ninomiya T

J Am Geriatr Soc   66   1911 - 1918   2018.10

The association between blood pressure variability (BPV) with dementia and cognitive function: a systematic review and meta-analysis protocol. Invited Reviewed International journal

VARIABLE BRAIN consortium( Ninomiya T, Ohara T, Oishi E)

Syst Rev   7   163   2018.10

Distribution of nephrologists and regional variation in the clinical severity of IgA nephropathy at biopsy diagnosis in Japan: a cross-sectional study. Invited Reviewed International journal

Okabayashi Y, Tsuboi N, Amano H, Miyazaki Y, Kawamura T, Ogura M, Narita I, Ninomiya T, Yokoyama H, Yokoo T

BMJ Open   8   e024317   2018.10

A potential novel pathological implication of serum soluble triggering receptor expressed on myeloid cell 2 in insulin resistance in a general Japanese population: the Hisayama Study. Reviewed International journal

Tanaka M, Honda T, Yamakage H, Hata J, Yoshida D, Hirakawa Y, Shibata M, Inoue T, Kusakabe T, Satoh-Asahara N, Ninomiya T

Diabetes Res Clin Pract   146   225 - 232   2018.10

Periodontal status and lung function decline in the community: the Hisayama Study. Invited Reviewed International journal

Takeuchi K, Matsumoto K, Furuta M, Fukuyama S, Takeshita T, Ogata H, Suma S, Shibata Y, Shimazaki Y, Hata J, Ninomiya T, Nakanishi Y, Inoue H, Yamashita Y

Sci Rep   8   13354   2018.9

Estimated glomerular filtration rate decline and risk of end-stage renal disease in type 2 diabetes. Invited Reviewed International journal

Oshima M, Toyama T, Haneda M, Furuichi K, Babazono T, Yokoyama H, Iseki K, Araki S, Ninomiya T, Hara S, Suzuki Y, Iwano M, Kusano E, Moriya T, Satoh H, Nakamura H, Shimizu M, Hara A, Makino H, Wada T; Research Group of Diabetic Nephropathy, Ministry of Health, Labour, and Welfare of Japan

PLoS One   13   e0201535   2018.8

Tongue microbiota and oral health status in community-dwelling elderly adults. Invited Reviewed International journal

Asakawa M, Takeshita T, Furuta M, Kageyama S, Takeuchi K, Hata J, Ninomiya T, Yamashita Y

mSphere   3   e00332 - -18   2018.8

Prevalence and risk factors for polypoidal choroidal vasculopathy in a general Japanese population: the Hisayama Study. Invited Reviewed International journal

Fujiwara K, Yasuda M, Hata J, Oshima Y, Hashimoto S, Yoshitomi T, Kiyohara Y, Ishibashi T, Ninomiya T, Sonoda KH

Semin Ophthalmol   33 ( 6 )   813 - 819   2018.7

Association between the ratio of serum arachidonic acid to eicosapentaenoic acid and the presence of depressive symptoms in a general Japanese population: the Hisayama Study. Invited Reviewed International journal

Shibata M, Ohara T, Yoshida D, Hata J, Mukai N, Kawano H, Kanba S, Kitazono T, Ninomiya T

J Affect Disord   237   73 - 79   2018.7

Relationships among Food Group Intakes, Household Expenditure, and Education Attainment in a General Japanese Population: NIPPON DATA2010. Invited Reviewed International journal

Nagahata T, Nakamura M, Ojima T, Kondo I, Ninomiya T, Yoshita K, Arai Y, Ohkubo T, Murakami K, Nishi N, Murakami Y, Takashima N, Okuda N, Kadota A, Miyagawa N, Kondo K, Okamura T, Ueshima H, Okayama A, Miura K

J Epidemiol   28(Supplement_III)   S23 - S28   2018.7

Socioeconomic Inequalities in Oral Health among Middle-Aged and Elderly Japanese: NIPPON DATA2010. Invited Reviewed International journal

Murakami K, Ohkubo T, Nakamura M, Ninomiya T, Ojima T, Shirai K, Nagahata T, Kadota A, Okuda N, Nishi N, Okamura T, Ueshima H, Okayama A, Miura K

J Epidemiol   28(Supplement_III)   S59 - S65   2018.7

Secular trends in the incidence of end-stage renal disease and its risk factors in Japanese patients with immunoglobulin A nephropathy. Invited Reviewed International journal

Tanaka S, Ninomiya T, Katafuchi R, Masutani K, Tsuchimoto A, Tokumoto M, Hirakata H, Ooboshi H, Kitazono T, Tsuruya K

Nephrol Dial Transplant   33   963 - 971   2018.6

Prevalence of and risk factors for cerebral microbleeds in a general Japanese elderly community. Invited Reviewed International journal

Yubi T, Hata J, Ohara T, Mukai N, Hirakawa Y, Yoshida D, Gotoh S, Hirabayashi N, Furuta Y, Ago T, Kitazono T, Kiyohara Y, Ninomiya T

Neurology: Clinical Practice   8   223 - 231   2018.6

Secular trends in the incidence, risk factors, and prognosis of transient ischemic attack in Japan: The Hisayama Study. Invited Reviewed International journal

Furuta Y, Hata J, Mukai N, Hirakawa Y, Ago T, Kitazono T, Kiyohara Y, Ninomiya T

Atherosclerosis   273   84 - 90   2018.6

Simultaneously Measured Interarm Blood Pressure Difference and Stroke: An Individual Participants Data Meta-Analysis. Invited Reviewed International journal

Tomiyama H, Ohkuma T, Ninomiya T, Mastumoto C, Kario K, Hoshide S, Kita Y, Inoguchi T, Maeda Y, Kohara K, Tabara Y, Nakamura M, Ohkubo T, Watada H, Munakata M, Ohishi M, Ito N, Nakamura M, Shoji T, Vlachopoulos C, Yamashina A; collaborative group for J-BA

Hypertension   71   1030 - 1038   2018.6

Association of extremely high levels of high-density lipoprotein cholesterol with cardiovascular mortality in a pooled analysis of 9 cohort studies including 43,407 individuals: The EPOCH-JAPAN study. Invited Reviewed International journal

J Clin Lipidol   12   674 - 684   2018.5

Clustering of risk factors and the risk of incident cardiovascular disease in Asian and Caucasian populations: results from the Asia Pacific Cohort Studies Collaboration. Invited Reviewed International journal

Peters SAE, Wang X, Lam TH, Kim HC, Ho S, Ninomiya T, Knuiman M, Vaartjes I, Bots ML, Woodward M; Asia Pacific Cohort Studies Collaboration (Hisayama: Ninomiya T, Hata J, Hirakawa Y)

BMJ Open   8: e019335,   2018.5

Development and validation of a risk assessment tool for gastric cancer in a general Japanese population. Invited Reviewed International journal

Iida M, Ikeda F, Hata J, Hirakawa Y, Ohara T, Mukai N, Yoshida D, Yonemoto K, Esaki M, Kitazono T, Kiyohara Y, Ninomiya T

Gastric Cancer   21   383 - -390   2018.5

Patterns and Levels of Sedentary Behavior and Physical Activity in a General Japanese Population: The Hisayama Study. Invited Reviewed International journal

Chen T, Kishimoto H, Honda T, Hata J, Yoshida D, Mukai N, Shibata M, Ninomiya T, Kumagai S

J Epidemiol   28   260 - 265   2018.5

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. Invited Reviewed International journal

MEGASTROKE Consortium( Ninomiya T, Hata J)

50   524 - 537   2018.4

Association of adipocyte enhancer-binding protein 1 with Alzheimer's disease pathology in human hippocampi. Invited Reviewed International journal

Shijo M, Honda H, Suzuki SO, Hamasaki H, Hokama M, Abolhassani N, Nakabeppu Y, Ninomiya T, Kitazono T, Iwaki T

Brain Pathol   28   58 - 71   2018.1

Albuminuria increases the risks for both Alzheimer disease and vascular dementia in community-dwelling Japanese elderly: the Hisayama Study. Invited Reviewed International journal

Takae K, Hata J, Ohara T, Yoshida D, Shibata M, Mukai N, Hirakawa Y, Kishimoto H, Tsuruya K, Kitazono T, Kiyohara Y, Ninomiya T

J Am Heart Assoc 7: e006693, 2018   7   e006693   2018.1

Comparative profiling of cortical gene expression in Alzheimer's disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation. Invited Reviewed International journal

Castillo E, Leon J, Mazzei G, Abolhassani N, Haruyama N, Saito T, Saido T, Hokama M, Iwaki T, Ohara T, Ninomiya T, Kiyohara Y, Sakumi K, LaFerla FM, Nakabeppu Y

Sci Rep   7   17762 - 17762   2017.12

The ratio of serum eicosapentaenoic acid to arachidonic acid and risk of cancer death in a Japanese community: the Hisayama Study. Invited Reviewed International journal

Nagata M, Hata J, Hirakawa Y, Mukai N, Yoshida D, Ohara T, Kishimoto H, Kawano H, Kitazono T, Kiyohara Y, Ninomiya T

J Epidemiol   27   578 - 583   2017.12

Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults. Invited Reviewed International journal

390   2627 - 2642   2017.11

White-coat and masked hypertension are associated with albuminuria in a general population: the Hisayama Study. Invited Reviewed International journal

Hata J, Fukuhara M, Sakata S, Arima H, Hirakawa Y, Yonemoto K, Mukai N, Kitazono T, Kiyohara Y, Ninomiya T

Hypertens Res   40   937 - 943   2017.11

Exploration of bacterial species associated with the salivary microbiome of individuals with a low susceptibility to dental caries. Invited Reviewed International journal

Yasunaga H, Takeshita T, Shibata Y, Furuta M, Shimazaki Y, Akifusa S, Ninomiya T, Kiyohara Y, Takahashi I, Yamashita Y

21   2399 - 2406   2017.11

Impact of blood urea nitrogen to creatinine ratio on mortality and morbidity in hemodialysis patients: The Q-Cohort Study. Invited Reviewed International journal

Tanaka S, Ninomiya T, Taniguchi M, Tokumoto M, Masutani K, Ooboshi H, Kitazono T, Tsuruya K

Sci Rep   7   14901 - 14909   2017.11

Association of airflow limitation with carotid atherosclerosis in a Japanese community　- the Hisayama Study. Invited Reviewed International journal

81   1846 - 1853   2017.11

Author response: Trends in dementia prevalence, incidence, and survival rate in a Japanese community. Invited Reviewed International journal

Ohara T, Ninomiya T

Neurology   89   1930 - 1931   2017.10

Morning and evening blood pressures are associated with intima-media thickness in a general population　- the Hisayama Study. Invited Reviewed International journal

81   1647 - 1653   2017.10

Proposed cutoff value of brachial-ankle pulse wave velocity for the management of hypertension. Invited Reviewed International journal

Ohkuma T, Tomiyama H, Ninomiya T, Kario K, Hoshide S, Kita Y, Inoguchi T, Maeda Y, Kohara K, Tabara Y, Nakamura M, Ohkubo T, Watada H, Munakata M, Ohishi M, Ito N, Nakamura M, Shoji T, Vlachopoulos C, Yamashina A; Collaborative Group for Japan Brachial-An

Circ J   81   1540 - 1542   2017.9

Erratum to "Characteristics and prognosis of Japanese colorectal cancer patients: The BioBank Japan Project" [J Epidemiol 27(3S) (2017) S36-S42]. Invited Reviewed International journal

Tamakoshi A, Nakamura K, Ukawa S, Okada E, Hirata M, Nagai A, Matsuda K, Kamatani Y, Muto K, Kiyohara Y, Yamagata Z, Ninomiya T, Kubo M, Nakamura Y; BioBank Japan Cooperative Hospital Group

J Epidemiol   27   398 - 399   2017.8

Alternative measures of hyperglycemia and risk of alzheimer's disease in the community: the Hisayama Study. Invited Reviewed International journal

Mukai N, Ohara T, Hata J, Hirakawa Y, Yoshida D, Kishimoto H, Koga M, Nakamura U, Kitazono T, Kiyohara Y, Ninomiya T

J Clin Endocrinol Metab   102 ( 8 )   3002 - 3010   2017.8

Association between serum vitamin D and all-cause and cause-specific death in a general Japanese population　- the Hisayama Study. Invited Reviewed International journal

81 ( 9 )   1315 - 1321   2017.8

Day-to-day blood pressure variability and risk of dementia in a general Japanese elderly population: the Hisayama Study. Invited Reviewed International journal

Oishi E, Ohara T, Sakata S, Fukuhara M, Hata J, Yoshida D, Shibata M, Ohtsubo T, Kitazono T, Kiyohara Y, Ninomiya T

Circulation   136   516 - 525   2017.8

Serum non-high-density lipoprotein cholesterol and risk of cardiovascular disease in community dwellers with chronic kidney disease: the Hisayama Study. Invited Reviewed International journal

Usui T, Nagata M, Hata J, Mukai N, Hirakawa Y, Yoshida D, Kishimoto H, Kitazono T, Kiyohara Y, Ninomiya T

J Atheroscler Thromb   24   706 - 715   2017.7

Chronic kidney disease in Asia: Protocol for a collaborative overview. Invited Reviewed International journal

Liyanage T, Ninomiya T, Perkovic V, Woodward M, Stirnadel-Farrant H, Matsushita K, Iseki K, Seong HL, Monaghan H, Jha V

Nephrology (Carlton)   22 ( 6 )   456 - 462   2017.6

Brachial-ankle pulse wave velocity and the risk prediction of cardiovascular disease: an individual oarticipant data meta-analysis. Invited Reviewed International journal

Ohkuma T, Ninomiya T, Tomiyama H, Kario K, Hoshide S, Kita Y, Inoguchi T, Maeda Y, Kohara K, Tabara Y, Nakamura M, Ohkubo T, Watada H, Munakata M, Ohishi M, Ito N, Nakamura M, Shoji T, Vlachopoulos C, Yamashina A; Collaborative Group for J-BAVEL

Hypertension   69   1045 - 1052   2017.6

The contribution of inflammation to the development of hypertension mediated by increased arterial stiffness. Invited Reviewed International journal

Tomiyama H, Shiina K, Matsumoto-Nakano C, Ninomiya T, Komatsu S, Kimura K, Chikamori T, Yamashina A

J Am Heart Assoc   6   e005729   2017.6

The Fukuoka Kidney disease Registry (FKR) Study: design and methods. Invited Reviewed International journal

Tanaka S, Ninomiya T, Fujisaki K, Yoshida H, Nagata M, Masutani K, Tokumoto M, Mitsuiki K, Hirakata H, Fujimi S, Kiyohara Y, Kitazono T, Tsuruya K; Fukuoka Kidney disease Registry (FKR) Study Collaboration Group

Clin Exp Nephrol   21 ( 3 )   465 - 473   2017.6

Trends in dementia prevalence, incidence, and survival rate in a Japanese community. Invited Reviewed International journal

Ohara T, Hata J, Yoshida D, Mukai N, Nagata M, Iwaki T, Kitazono T, Kanba S, Kiyohara Y, Ninomiya T

Neurology   88   1925 - 1932   2017.5

Tooth loss and risk of dementia in the community: the Hisayama Study. Invited Reviewed International journal

Takeuchi K, Ohara T, Furuta M, Takeshita T, Shibata Y, Hata J, Yoshida D, Yamashita Y, Ninomiya T

J Am Geriatr Soc   65   e95 - e100   2017.5

Development of a self-scored persistent airflow obstruction screening questionnaire in a general Japanese population: the Hisayama Study. Invited Reviewed International journal

Ozawa M, Yoshida D, Hata J, Ohara T, Mukai N, Shibata M, Uchida K, Nagata M, Kitazono T, Kiyohara Y, Ninomiya T

Int J Chron Obstruct Pulmon Dis   12   1469 - 1481   2017.5

Risk prediction models for mortality in patients with cardiovascular disease: The BioBank Japan project. Invited Reviewed International journal

Hata J, Nagai A, Hirata M, Kamatani Y, Tamakoshi A, Yamagata Z, Muto K, Matsuda K, Kubo M, Nakamura Y; Biobank Japan Cooperative Hospital Group., Kiyohara Y, Ninomiya T; Collaborator

J Epidemiol   27 ( 3s )   S71 - S76   2017.3

Clinical and histopathological characteristics of patients with prostate cancer in the BioBank Japan project. Invited Reviewed International journal

Ukawa S, Nakamura K, Okada E, Hirata M, Nagai A, Yamagata Z, Muto K, Matsuda K, Ninomiya T, Kiyohara Y, Kamatani Y, Kubo M, Nakamura Y; BioBank Japan Cooperative Hospital Group., Tamakoshi A

J Epidemiol   27   S65 - S70   2017.3

Stimulated salivary flow rate and oral health status. Invited Reviewed International journal

Shimazaki Y, Fu B, Yonemoto K, Akifusa S, Shibata Y, Takeshita T, Ninomiya T, Kiyohara Y, Yamashita Y

J Oral Sci   59 ( 1 )   55 - 62   2017.3

Characteristics and prognosis of Japanese colorectal cancer patients: The BioBank Japan Project. Invited Reviewed International journal

Tamakoshi A, Nakamura K, Ukawa S, Okada E, Hirata M, Nagai A, Matsuda K, Kamatani Y, Muto K, Kiyohara Y, Yamagata Z, Ninomiya T, Kubo M, Nakamura Y; BioBank Japan Cooperative Hospital Group

J Epidemiol   27 ( 3s )   S36 - S42   2017.3

Cholesterol levels of Japanese dyslipidaemic patients with various comorbidities: BioBank Japan. Invited Reviewed International journal

Yokomichi H, Noda H, Nagai A, Hirata M, Tamakoshi A, Kamatani Y, Kiyohara Y, Matsuda K, Muto K, Ninomiya T, Kubo M, Nakamura Y; BioBank Japan Cooperative Hospital Group., Yamagata Z

J Epidemiol   27 ( 3s )   S77 - S83   2017.3

Statin use and all-cause and cancer mortality: BioBank Japan cohort. Invited Reviewed International journal

Yokomichi H, Nagai A, Hirata M, Tamakoshi A, Kiyohara Y, Kamatani Y, Muto K, Ninomiya T, Matsuda K, Kubo M, Nakamura Y; BioBank Japan Cooperative Hospital Group., Yamagata Z

J Epidemiol   27 ( 3s )   S84 - S91   2017.3

Overview of BioBank Japan follow-up data in 32 diseases. Invited Reviewed International journal

Hirata M, Nagai A, Kamatani Y, Ninomiya T, Tamakoshi A, Yamagata Z, Kubo M, Muto K, Kiyohara Y, Mushiroda T, Murakami Y, Yuji K, Furukawa Y, Zembutsu H, Tanaka T, Ohnishi Y, Nakamura Y; BioBank Japan Cooperative Hospital Group., Matsuda K

J Epidemiol   27 ( 3s )   S22 - S28   2017.3

Cross-sectional analysis of BioBank Japan clinical data: A large cohort of 200,000 patients with 47 common diseases. Invited Reviewed International journal

Hirata M, Kamatani Y, Nagai A, Kiyohara Y, Ninomiya T, Tamakoshi A, Yamagata Z, Kubo M, Muto K, Mushiroda T, Murakami Y, Yuji K, Furukawa Y, Zembutsu H, Tanaka T, Ohnishi Y, Nakamura Y; BioBank Japan Cooperative Hospital Group., Matsuda K

J Epidemiol   27 ( 3s )   S9 - S21   2017.3

Age-specific impact of diabetes mellitus on the risk of cardiovascular mortality: An overview from the evidence for Cardiovascular Prevention from Observational Cohorts in the Japan Research Group (EPOCH-JAPAN). Invited Reviewed International journal

Hirakawa Y, Ninomiya T, Kiyohara Y, Murakami Y, Saitoh S, Nakagawa H, Okayama A, Tamakoshi A, Sakata K, Miura K, Ueshima H, Okamura T; Evidence for Cardiovascular Prevention From Observational Cohorts in Japan Research Group (EPOCH-JAPAN)

J Epidemiol   27 ( 3 )   123 - 129   2017.3

Characteristics and prognosis of Japanese female breast cancer patients: The BioBank Japan project. Invited Reviewed International journal

Nakamura K, Okada E, Ukawa S, Hirata M, Nagai A, Yamagata Z, Kiyohara Y, Muto K, Kamatani Y, Ninomiya T, Matsuda K, Kubo M, Nakamura Y; BioBank Japan Cooperative Hospital Group., Tamakoshi A

J Epidemiol   27 ( 3 )   S58 - S64   2017.3

Characteristics of patients with liver cancer in the BioBank Japan project. Invited Reviewed International journal

Ukawa S, Okada E, Nakamura K, Hirata M, Nagai A, Matsuda K, Yamagata Z, Kamatani Y, Ninomiya T, Kiyohara Y, Muto K, Kubo M, Nakamura Y; BioBank Japan Cooperative Hospital Group., Tamakoshi A

J Epidemiol   27 ( 3s )   S43 - S48   2017.3

Survival of macrovascular disease, chronic kidney disease, chronic respiratory disease, cancer and smoking in patients with type 2 diabetes: BioBank Japan cohort. Invited Reviewed International journal

Yokomichi H, Nagai A, Hirata M, Kiyohara Y, Muto K, Ninomiya T, Matsuda K, Kamatani Y, Tamakoshi A, Kubo M, Nakamura Y; BioBank Japan Cooperative Hospital Group., Yamagata Z

J Epidemiol   27 ( 3s )   S98 - S106   2017.3

Characteristics and prognosis of Japanese male and female lung cancer patients: The BioBank Japan Project. Invited Reviewed International journal

Nakamura K, Ukawa S, Okada E, Hirata M, Nagai A, Yamagata Z, Ninomiya T, Muto K, Kiyohara Y, Matsuda K, Kamatani Y, Kubo M, Nakamura Y; BioBank Japan Cooperative Hospital Group., Tamakoshi A

J Epidemiol   27 ( 3s )   S49 - S57   2017.3

Demographic and lifestyle factors and survival among patients with esophageal and gastric cancer: The Biobank Japan Project. Invited Reviewed International journal

Okada E, Ukawa S, Nakamura K, Hirata M, Nagai A, Matsuda K, Ninomiya T, Kiyohara Y, Muto K, Kamatani Y, Yamagata Z, Kubo M, Nakamura Y; BioBank Japan Cooperative Hospital Group., Tamakoshi A

J Epidemiol   27 ( 3s )   S29 - S35   2017.3

Overview of the BioBank Japan Project: Study design and profile. Invited Reviewed International journal

Nagai A, Hirata M, Kamatani Y, Muto K, Matsuda K, Kiyohara Y, Ninomiya T, Tamakoshi A, Yamagata Z, Mushiroda T, Murakami Y, Yuji K, Furukawa Y, Zembutsu H, Tanaka T, Ohnishi Y, Nakamura Y; BioBank Japan Cooperative Hospital Group., Kubo M

J Epidemiol   27 ( 3s )   S2 - S8   2017.3

Serum glucose, cholesterol and blood pressure levels in Japanese type 1 and 2 diabetic patients: BioBank Japan. Invited Reviewed International journal

Yokomichi H, Nagai A, Hirata M, Kiyohara Y, Muto K, Ninomiya T, Matsuda K, Kamatani Y, Tamakoshi A, Kubo M, Nakamura Y; BioBank Japan Cooperative Hospital Group., Yamagata Z

J Epidemiol   27 ( 3s )   S92 - S97   2017.3

Genetic predisposition to ischemic stroke: a polygenic risk score. Invited Reviewed International journal

Hachiya T, Kamatani Y, Takahashi A, Hata J, Furukawa R, Shiwa Y, Yamaji T, Hara M, Tanno K, Ohmomo H, Ono K, Takashima N, Matsuda K, Wakai K, Sawada N, Iwasaki M, Yamagishi K, Ago T, Ninomiya T, Fukushima A, Hozawa A, Minegishi N, Satoh M, Endo R, Sasaki

Stroke   48 ( 2 )   253 - 258   2017.2

Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants. Invited Reviewed International journal

389   37 - 55   2017.1

Combination of Helicobacter pylori Antibody and Serum Pepsinogen as a Good Predictive Tool of Gastric Cancer Incidence: 20-Year Prospective Data From the Hisayama Study. Invited Reviewed International journal

Ikeda F, Shikata K, Hata J, Fukuhara M, Hirakawa Y, Ohara T, Mukai N, Nagata M, Yoshida D, Yonemoto K, Esaki M, Kitazono T, Kiyohara Y, Ninomiya T

J Epidemiol   26 ( 12 )   629 - 636   2016.12

Association Between Diabetes and Hippocampal Atrophy in Elderly Japanese: the Hisayama Study. Invited Reviewed International journal

Hirabayashi N, Hata J, Ohara T, Mukai N, Nagata M, Shibata M, Gotoh S, Furuta Y, Yamashita F, Yoshihara K, Kitazono T, Sudo N, Kiyohara Y, Ninomiya T

Diabetes Care   39 ( 9 )   1543 - 1549   2016.9

Serum Angiopoietin-Like Protein 2 Is a Novel Risk Factor for Cardiovascular Disease in the Community: the Hisayama Study. Invited Reviewed International journal

Hata J, Mukai N, Nagata M, Ohara T, Yoshida D, Kishimoto H, Shibata M, Hirakawa Y, Endo M, Ago T, Kitazono T, Oike Y, Kiyohara Y, Ninomiya T

Arterioscler Thromb Vasc Biol   36 ( 8 )   1686 - 1691   2016.8

Interventions for lowering plasma homocysteine levels in kidney transplant recipients. Invited Reviewed International journal

Kang A, Nigwekar SU, Perkovic V, Kulshrestha S, Zoungas S, Navaneethan SD, Cass A, Gallagher MP, Ninomiy T, Strippoli GF, Jardine MJ

Cochrane Database Syst Rev   5   2016.8

Effects of the Mediterranean Diet on Cardiovascular Outcomes-A Systematic Review and Meta-Analysis. Invited Reviewed International journal

Liyanage T, Ninomiya T, Wang A, Neal B, Jun M, Wong MG, Jardine M, Hillis GS, Perkovic V.

PLoS One   11 ( 8 )   2016.8

Comparison of the COPD Population Screener and International Primary Care Airway Group questionnaires in a general Japanese population: the Hisayama study. Invited Reviewed International journal

Tsukuya G, Samukawa T, Matsumoto K, Fukuyama S, Kumamoto T, Uchida A, Koriyama C, Ninomiya T, Inoue H

Int J Chron Obstruct Pulmon Dis   11 ( 8 )   1903 - 1909   2016.8

A century of trends in adult human height Invited Reviewed International journal

NCD Risk Factor Collaboration (NCD-RisC) (Ninomiya T, Hata J)

Elife. 2016 Jul 26;5:e13410.   2016.7

Serum Uric Acid as a Risk Factor for Chronic Kidney Disease in a Japanese Community - the Hisayama Study -. Invited Reviewed International journal

Takae K, Nagata M, Hata J, Mukai N, Hirakawa Y, Yoshida D, Kishimoto H, Tsuruya K, Kitazono T, Kiyohara Y, Ninomiya T

Circ J   80 ( 8 )   1857 - 1862   2016.7

Perceived inadequate care and excessive overprotection during childhood are associated with greater risk of sleep disturbance in adulthood: the Hisayama Study. Invited Reviewed International journal

Shibata M, Ninomiya T, Anno K, Kawata H, Iwaki R, Sawamoto R, Kubo C, Kiyohara Y, Sudo N, Hosoi M

BMC Psychiatry   16   215   2016.7

Foveal and Macular Thickness in a Japanese Population: the Hisayama Study. Invited Reviewed International journal

Hashimoto S, Yasuda M, Ninomiya T, Hata J, Yoshida D, Tahara-Asakuma T, Hirakawa Y, Arakawa S, Fujiwara K, Kiyohara Y, Ishibashi T

Ophthalmic Epidemiol   23   202 - 208   2016.6

Admission Heart Rate Predicts Poor Outcomes in Acute Intracerebral Hemorrhage: The Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial Studies. Invited Reviewed International journal

Qiu M, Sato S, Zheng D, Wang X, Carcel C, Hirakawa Y, Sandset EC, Delcourt C, Arima H, Wang J, Chalmers J, Anderson CS; INTERACT Investigators

Stroke   47 ( 6 )   1479 - 1485   2016.6

Renin-angiotensin system inhibitors and kidney and cardiovascular outcomes in patients with CKD: a Bayesian network meta-analysis of randomized clinical trials. Invited Reviewed International journal

Xie X, Liu Y, Perkovic V, Li X, Ninomiya T, Hou W, Zhao N, Liu L, Lv J, Zhang H, Wang H

Am J Kidney Dis   2016.5

Trends in autopsy-verified dementia prevalence over 29 years of the Hisayama study. Invited Reviewed International journal

Honda H, Sasaki K, Hamasaki H, Shijo M, Koyama S, Ohara T, Ninomiya T, Kiyohara Y, Suzuki SO, Iwaki T

Neuropathology   2016.5

Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4.4 million participants. Invited Reviewed International journal

NCD Risk Factor Collaboration (NCD-RisC) (Hata J, Ninomiya T)

Lancet   387   1513 - 1530   2016.4

Risks associated with permanent discontinuation of blood pressure-lowering medications in patients with type 2 diabetes. Invited Reviewed International journal

Hirakawa Y, Arima H, Webster R, Zoungas S, Li Q, Harrap S, Lisheng L, Hamet P, Mancia G, Poulter N, Neal B, Williams B, Rogers A, Woodward M, Chalmers J

J Hypertens   34 ( 4 )   781 - 787   2016.4

Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants. Invited Reviewed International journal

387   1377 - 1396   2016.4

The long-term association between physical activity and risk of dementia in the community: the Hisayama Study. Invited Reviewed International journal

Kishimoto H, Ohara T, Hata J, Ninomiya T, Yoshida D, Mukai N, Nagata M, Ikeda F, Fukuhara M, Kumagai S, Kanba S, Kitazono T, Kiyohara Y

Eur J Epidemiol   2016.3

Recent Increases in Hippocampal Tau Pathology in the Aging Japanese Population: the Hisayama Study. Invited Reviewed International journal

Hamasaki H, Honda H, Okamoto T, Koyama S, Suzuki SO, Ohara T, Ninomiya T, Kiyohara Y, Iwaki T

J Alzheimers Dis   55 ( 2 )   613 - 624   2016.2

Bacterial diversity in saliva and oral health-related conditions: the Hisayama Study. Invited Reviewed International journal

Takeshita T, Kageyama S, Furuta M, Tsuboi H, Takeuchi K, Shibata Y, Shimazaki Y, Akifusa S, Ninomiya T, Kiyohara Y, Yamashita Y

Sci Rep   2016.2

Type 2 Diabetes as a Risk Factor for Dementia in Women Compared With Men: A Pooled Analysis of 2.3 Million People Comprising More Than 100,000 Cases of Dementia. Invited Reviewed International journal

Chatterjee S, Peters SA, Woodward M, Mejia Arango S, Batty GD, Beckett N, Beiser A, Borenstein AR, Crane PK, Haan M, Hassing LB, Hayden KM, Kiyohara Y, Larson EB, Li CY, Ninomiya T, Ohara T, Peters R, Russ TC, Seshadri S, Strand BH, Walker R, Xu W, Huxley RR

Diabetes Care   39   300 - 307   2016.2

Is a reduction in albuminuria associated with renal and cardiovascular protection? A post-hoc analysis of the ALTITUDE trial. Invited Reviewed International journal

Lambers Heerspink HJ, Ninomiya T, Persson F, Brenner BM, Brunel P, Chaturvedi N, Desai AS, Haffner SM, Mcmurray JJ, Solomon SD, Pfeffer MA, Parving HH, de Zeeuw D

Diabetes Obes Metab   18   169 - 77   2016.2

Effects of intensive blood pressure lowering on cardiovascular and renal outcomes: updated systematic review and meta-analysis. Invited Reviewed International journal

Xie X, Atkins E, Lv J, Bennett A, Neal B, Ninomiya T, Woodward M, MacMahon S, Turnbull F, Hillis GS, Chalmers J, Mant J, Salam A, Rahimi K, Perkovic V, Rodgers A

Lancet   387   435 - 443   2016.1

Prognostic impact of serum bilirubin level on long-term renal survival in IgA nephropathy. Invited Reviewed International journal

Tanaka S, Ninomiya T, Masutani K, Nagata M, Tsuchimoto A, Tsuruya K, Kitazono T

Clin Exp Nephrol   19   1062 - 1070   2015.12

Insulin Resistance Is a Risk Factor for Increased Intraocular Pressure: The Hisayama Study. Invited Reviewed International journal

Fujiwara K, Yasuda M, Ninomiya T, Hata J, Hashimoto S, Yoshitomi T, Kiyohara Y, Ishibashi T

Invest Ophthalmol Vis Sci   56   7983 - 7987   2015.12

The effect of renin-angiotensin system blockade on the incidence of end-stage renal disease in IgA nephropathy. Invited Reviewed International journal

Tanaka S, Ninomiya T, Katafuchi R, Masutani K, Nagata M, Tsuchimoto A, Hirakata H, Kitazono T, Tsuruya K

Clin Exp Nephrol   2015.11

Midlife and Late-Life Smoking and Risk of Dementia in the Community: The Hisayama Study. Invited Reviewed International journal

Ohara T, Ninomiya T, Hata J, Ozawa M, Yoshida D, Mukai N, Nagata M, Iwaki T, Kitazono T, Kanba S, Kiyohara Y

J Am Geriatr Soc   63   2332 - 2339   2015.11

Association between eating rate and obesity: a systematic review and meta-analysis. Invited Reviewed International journal

Ohkuma T, Hirakawa Y, Nakamura U, Kiyohara Y, Kitazono T, Ninomiya T.

Int J Obes (Lond)   39   1589 - 1596   2015.11

Angiotensin I-converting enzyme gene polymorphism enhances the effect of hypercholesterolemia on the risk of coronary heart disease in a general Japanese population: the Hisayama Study. Invited Reviewed International journal

Kondo H, Ninomiya T, Hata J, Hirakawa Y, Yonemoto K, Arima H, Nagata M, Tsuruya K, Kitazono T, Kiyohara Y

J Atheroscler Thromb   22   390 - 403   2015.10

Hematocrit and the risk of cardiovascular disease in a Japanese community: the Hisayama Study Invited Reviewed International journal

Gotoh S, Hata J, Ninomiya T, Hirakawa Y, Nagata M, Mukai N, Fukuhara M, Ikeda F, Ago T, Kitazono T, Kiyohara Y

Atherosclerosis   242   199 - 204   2015.9

Serum antibody to Porphyromonas gingivalis and periodontitis progression: the Hisayama Study. Invited Reviewed International journal

Takeuchi K, Furuta M, Takeshita T, Shibata Y, Shimazaki Y, Akifusa S, Ninomiya T, Kiyohara Y, Yamashita Y

J Clin Periodontol   42   719 - 725   2015.8

Effects of diabetes definition on global surveillance of diabetes prevalence and diagnosis: a pooled analysis of 96 population-based studies with 331,288 participants. Invited Reviewed International journal

NCD Risk Factor Collaboration (Ninomiya T)

Lancet Diabetes Endocrinol   8   624 - 637   2015.8

A genome-wide association study of late-onset Alzheimer's disease in a Japanese population. Invited Reviewed International journal

Hirano A, Ohara T, Takahashi A, Aoki M, Fuyuno Y, Ashikawa K, Morihara T, Takeda M, Kamino K, Oshima E, Okahisa Y, Shibata N, Arai H, Akatsu H, Ikeda M, Iwata N, Ninomiya T, Monji A, Kitazono T, Kiyohara Y, Kubo M, Kanba S

Psychiatr Genet   25   139 - 146   2015.8

Paternal and maternal bonding styles in childhood are associated with the prevalence of chronic pain in a general adult population: the Hisayama Study. Invited Reviewed International journal

Anno K, Shibata M, Ninomiya T, Iwaki R, Kawata H, Sawamoto R, Kubo C, Kiyohara Y, Sudo N, Hosoi M

BMC Psychiatry   15   181 - 181   2015.7

Health-related quality of life in survivors of acute kidney injury: the Prolonged Outcomes Study of the Randomized Evaluation of Normal versus Augmented Level Replacement Therapy study outcomes. Invited Reviewed International journal

Wang AY, Bellomo R, Cass A, Finfer S, Gattas D, Myburgh J, Chadban S, Hirakawa Y, Ninomiya T, Li Q, Lo S, Barzi F, Sukkar L, Jardine M, Gallagher MP; POST-RENAL Study Investigators and the ANZICS Clinical Trials Group:

Nephrology (Carlton)   20   492 - 498   2015.7

Association of hemoglobin A1c and glycated albumin with carotid atherosclerosis in community-dwelling Japanese subjects: the Hisayama Study. Invited Reviewed International journal

Mukai N, Ninomiya T, Hata J, Hirakawa Y, Ikeda F, Fukuhara M, Hotta T, Koga M, Nakamura U, Kang D, Kitazono T, Kiyohara Y

Cardiovasc Diabetol   14   84 - 84   2015.6

Worldwide access to treatment for end-stage kidney disease: a systematic review Reviewed International journal

Liyanage T, Ninomiya T (Double first author), Jha V, Neal B, Patrice HM, Okpechi I, Zhao MH, Lv J, Garg AX, Knight J, Rodgers A, Gallagher M, Kotwal S, Cass A, Perkovic V

Lancet   6736   61601 - 61609   2015.5

Hyporesponsiveness to erythropoiesis-stimulating agent as a prognostic factor in Japanese hemodialysis patients: the Q-Cohort study. International journal

Eriguchi R, Taniguchi M, Ninomiya T, Hirakata H, Fujimi S, Tsuruya K, Kitazono T

J Nephrol   28   217 - 225   2015.4

Risk factors for reduced salivary flow rate in a Japanese population: the Hisayama study International journal

Takeuchi K, Furuta M, Takeshita T, Shibata Y, Shimazaki Y, Akifusa S, Ninomiya T, Kiyohara Y, Yamashita Y.

Biomed Res Int   381821   2015.2

Hisayama Pulmonary Physiology Study Group. International journal

Tsukuya G, Matsumoto K, Fukuyama S, Crawford B, Nakanishi Y, Ichinose M, Machida K, Samukawa T, Ninomiya T, Kiyohara Y, Inoue H

Allergol Int   64   49 - 53   2015.1

Dietary patterns and clinical outcomes in hemodialysis patients in Japan: a cohort study. International journal

Tsuruya K, Fukuma S, Wakita T, Ninomiya T, Nagata M, Yoshida H, Fujimi S, Kiyohara Y, Kitazono T, Uchida K, Shirota T, Akizawa T, Akiba T, Saito A, Fukuhara S.

PLoS One   21 ( 10(1) )   e0116677   2015.1

Distinct composition of the oral indigenous microbiota in South Korean and Japanese adults. Invited Reviewed International journal

Takeshita T, Matsuo K, Furuta M, Shibata Y, Fukami K, Shimazaki Y, Akifusa S, Han DH, Kim HD, Yokoyama T, Ninomiya T, Kiyohara Y, Yamashita Y.

Sci Rep   4   6990   2014.11

Angiotensin-converting enzyme inhibitor usage and acute kidney injury: a secondary analysis of RENAL study outcomes Reviewed International journal

Wang AY, Bellomo R, Ninomiya T, Lo S, Cass A, Jardine M, Gallagher M; RENAL Study Investigators; ANZICS Clinical Trials Group

Nephrology (Carlton)   19   617 - 622   2014.10

Altered expression of diabetes-related genes in Alzheimer's disease brains: the Hisayama Study. Invited Reviewed International journal

Hokama M, Oka S, Leon J, Ninomiya T, Honda H, Sasaki K, Iwaki T, Ohara T, Sasaki T, Laferla FM, Kiyohara Y, Nakabeppu Y.

Cereb Cortex   24   2476 - 2488   2014.9

Cardiovascular disease, chronic kidney disease, and diabetes mortality burden of cardiometabolic risk factors from 1980 to 2010: a comparative risk assessment. Invited Reviewed International journal

Global Burden of Metabolic Risk Factors for Chronic Diseases Collaboration (Doi Y, Hata J, Kiyohara Y, Ninomiya T).

Lancet Diabetes Endocrinol   2   634 - 647   2014.8

Impact of visit-to-visit glycemic variability on the risks of macrovascular and microvascular events and all-cause mortality in type 2 diabetes: the ADVANCE Trial. Invited Reviewed International journal

Hirakawa Y, Arima H, Zoungas S, Ninomiya T, Cooper M, Hamet P, Mancia G, Poulter N, Harrap S, Woodward M, Chalmers J

Diabetes Care   2014.8

Milk and dairy consumption and risk of dementia in an elderly Japanese population: the hisayama study Reviewed International journal

Ozawa M, Ohara T, Ninomiya T, Hata J, Yoshida D, Mukai N, Nagata M, Uchida K, Shirota T, Kitazono T, Kiyohara Y

J Am Geriatr Soc   62   1224 - 1230   2014.7

Midlife and late-life handgrip strength and risk of cause-specific death in a general Japanese population: the Hisayama Study Reviewed International journal

Kishimoto H, Hata J, Ninomiya T, Nemeth H, Hirakawa Y, Yoshida D, Kumagai S, Kitazono T, Kiyohara Y

J Epidemiol Community Health   68   663 - 668   2014.7

The Research Group of Diabetic Nephropathy, Ministry of Health, Labour, and Welfare of Japan. Clinical impact of albuminuria and glomerular filtration rate on renal and cardiovascular events, and all-cause mortality in Japanese patients with type 2 diabetes. Invited Reviewed International journal

Wada T, Haneda M, Furuichi K, Babazono T, Yokoyama H, Iseki K, Araki SI, Ninomiya T, Hara S, Suzuki Y, Iwano M, Kusano E, Moriya T, Satoh H, Nakamura H, Shimizu M, Toyama T, Hara A, Makino H

Clin Exp Nephrol   18   621 - 622   2014.6

Effect of hemodiafiltration or hemofiltration compared with hemodialysis on mortality and cardiovascular disease in chronic kidney failure: a systematic review and meta-analysis of randomized trials Reviewed International journal

Wang AY, Ninomiya T, Al-Kahwa A, Perkovic V, Gallagher MP, Hawley C, Jardine MJ

Am J Kidney Dis   63   968 - 978   2014.6

A Low Ankle Brachial Index is Associated with an Increased Risk of Cardiovascular Disease: The Hisayama Study Reviewed International journal

Kojima I, Ninomiya T, Hata J, Fukuhara M, Hirakawa Y, Mukai N, Yoshida D, Kitazono T, Kiyohara Y

J Atheroscler Thromb   21   966 - 973   2014.4

Non-high-density lipoprotein cholesterol and the development of coronary heart disease and stroke subtypes in a general Japanese population: the Hisayama Study Reviewed International journal

Imamura T, Doi Y, Ninomiya T, Hata J, Nagata M, Ikeda F, Mukai N, Hirakawa Y, Yoshida D, Fukuhara M, Kitazono T, Kiyohara Y

Atherosclerosis   233   343 - 348   2014.4

Glycated hemoglobin measurement and prediction of cardiovascular disease. Invited Reviewed International journal

Emerging Risk Factors Collaboration (Kiyohara Y, Arima H, Ninomiya T, Hata J).

JAMA   311   1225 - 1233   2014.3

The construction of risk prediction models using GWAS data and its application to a type 2 diabetes prospective cohort. Invited Reviewed International journal

Shigemizu D, Abe T, Morizono T, Johnson TA, Boroevich KA, Hirakawa Y, Ninomiya T, Kiyohara Y, Kubo M, Nakamura Y, Maeda S, Tsunoda T

PLoS One   20   e92549   2014.3

Metabolic mediators of the effects of body-mass index, overweight, and obesity on coronary heart disease and stroke: a pooled analysis of 97 prospective cohorts with 1·8 million participants. Invited Reviewed International journal

383   970 - 983   2014.3

Assessing risk prediction models using individual participant data from multiple studies. Invited Reviewed International journal

Pennells L, Kaptoge S, White IR, Thompson SG, Wood AM; Emerging Risk Factors Collaboration (Kiyohara Y, Arima H, Doi Y, Ninomiya T).

Am J Epidemiol   179   621 - 632   2014.3

Trends in the prevalence of type 2 diabetes and prediabetes in community-dwelling Japanese subjects: The Hisayama Study Reviewed International journal

Mukai N, Doi Y, Ninomiya T, Hirakawa Y, Nagata M, Yoshida D, Hata J, Fukuhara M, Nakamura U, Kitazono T, Kiyohara Y

J Diabetes Investig   5   162 - 169   2014.3

Alexithymia is associated with greater risk of chronic pain and negative affect and with lower life satisfaction in a general population: the Hisayama Study Reviewed International journal

Shibata M, Ninomiya T, Jensen MP, Anno K, Yonemoto K, Makino S, Iwaki R, Yamashiro K, Yoshida T, Imada Y, Kubo C, Kiyohara Y, Sudo N, Hosoi M

PLoS One   12   2014.3

Role of endothelial cell-derived angptl2 in vascular inflammation leading to endothelial dysfunction and atherosclerosis progression. Invited Reviewed International journal

Horio E, Kadomatsu T, Miyata K, Arai Y, Hosokawa K, Doi Y, Ninomiya T, Horiguchi H, Endo M, Tabata M, Tazume H, Tian Z, Takahashi O, Terada K, Takeya M, Hao H, Hirose N, Minami T, Suda T, Kiyohara Y, Ogawa H, Kaikita K, Oike Y

Arterioscler Thromb Vasc Biol   34   790 - 800   2014.2

ABCD3 and ABCD3-I Scores Are Superior to ABCD2 Score in the Prediction of Short- and Long-Term Risks of Stroke After Transient Ischemic Attack. Invited Reviewed International journal

Kiyohara T, Kamouchi M, Kumai Y, Ninomiya T, Hata J, Yoshimura S, Ago T, Okada Y, Kitazono T; for the FSR investigators; Fukuoka Stroke Registry Investigators

Stroke   45   418 - 425   2014.2

Thresholds of various glycemic measures for diagnosing diabetes based on prevalence of retinopathy in community-dwelling Japanese subjects: the Hisayama Study Reviewed International journal

Mukai N, Yasuda M, Ninomiya T, Hata J, Hirakawa Y, Ikeda F, Fukuhara M, Hotta T, Koga M, Nakamura U, Kang D, Kitazono T, Kiyohara Y

Cardiovasc Diabetol   13   2014.2

Serum 1,25-Dihydroxyvitamin D and the Development of Kidney Dysfunction in a Japanese Community Reviewed International journal

Izumaru K, Ninomiya T, Nagata M, Usui T, Yoshida D, Yonemoto K, Fukuhara M, Tsuruya K, Kitazono T, Kiyohara Y

Circ J 2014   78   732 - 737   2014.1

Trends in the incidence and survival of intracerebral hemorrhage by its location in a Japanese community Reviewed International journal

Gotoh S, Hata J, Ninomiya T, Hirakawa Y, Nagata M, Mukai N, Fukuhara M, Ikeda F, Shikata K, Kamouchi M, Kitazono T, Kiyohara Y

Circ J   78   403 - 409   2014.1

Association between ratio of serum eicosapentaenoic acid to arachidonic acid and risk of cardiovascular disease: the Hisayama Study Reviewed International journal

Ninomiya T, Nagata M, Hata J, Hirakawa Y, Ozawa M, Yoshida D, Ohara T, Kishimoto H, Mukai N, Fukuhara M, Kitazono T, Kiyohara Y

Atherosclerosis   231   261 - 267   2013.12

Haemoglobin A1c even within non-diabetic level is a predictor of cardiovascular disease in a general Japanese population: the Hisayama Study Reviewed International journal

Ikeda F, Doi Y, Ninomiya T, Hirakawa Y, Mukai N, Hata J, Shikata K, Yoshida D, Matsumoto T, Kitazono T, Kiyohara Y

Cardiovasc Diabetol   12   2013.11

HLA-A2, HLA-B44 and HLA-DR15 are associated with lower risk of BK viremia Reviewed International journal

Masutani K, Ninomiya T, Randhawa P

Nephrol Dial Transplant   28   3119 - 3126   2013.11

Development and validation of a prediction rule using the Oxford classification in IgA nephropathy Reviewed International journal

Tanaka S, Ninomiya T, Katafuchi R, Masutani K, Tsuchimoto A, Noguchi H, Hirakata H, Tsuruya K, Kitazono T

Clin J Am Soc Nephrol   8   2082 - 2090   2013.11

Blood pressure lowering and major cardiovascular events in people with and without chronic kidney disease: meta-analysis of randomised controlled trials Reviewed International journal

BMJ   347   2013.10

Elevated depressive symptoms in metabolic syndrome in a general population of Japanese men: a cross-sectional study Reviewed International journal

Sekita A, Arima H, Ninomiya T, Ohara T, Doi Y, Hirakawa Y, Fukuhara M, Hata J, Yonemoto K, Ga Y, Kitazono T, Kanba S, Kiyohara Y

BMC Public Health   13   2013.9

Secular trends in cardiovascular disease and its risk factors in Japanese: half century data from the Hisayama Study Reviewed International journal

Hata J, Ninomiya T, Hirakawa Y, Nagata M, Mukai N, Gotoh S, Fukuhara M, Ikeda F, Shikata K, Yoshida D, Yonemoto K, Kamouchi M, Kitazono T, Kiyohara Y

Circulation   128   1198 - 1205   2013.9

Gender differences in the association between metabolic syndrome and periodontal disease: the Hisayama Study. Invited Reviewed International journal

Furuta M, Shimazaki Y, Takeshita T, Shibata Y, Akifusa S, Eshima N, Kiyohara Y, Ninomiya T, Hirakawa Y, Mukai N, Nagata M, Yamashita Y

J Clin Periodontol   40   743 - 752   2013.8

Effects of intensive blood pressure lowering on the progression of chronic kidney disease: a systematic review and meta-analysis. Invited Reviewed International journal

Lv J, Ehteshami P, Sarnak MJ, Tighiouart H, Jun M, Ninomiya T, Foote C, Rodgers A, Hong Z, Wang H, Strippoli GF, Perkovic V

CMAJ   185   949 - 957   2013.8

The impacts of albuminuria and low eGFR on the risk of cardiovascular death, all-cause mortality, and renal events in diabetic patients: meta-analysis Reviewed International journal

Toyama T, Furuichi K, Ninomiya T, Shimizu M, Hara A, Iwata Y, Kaneko S, Wada T

PLoS One   8   2013.8

Chronic kidney disease is associated with neovascularization and intraplaque hemorrhage in coronary atherosclerosis in elders: results from the Hisayama Study Reviewed International journal

Nakano T, Ninomiya T, Sumiyoshi S, Onimaru M, Fujii H, Itabe H, Nakashima Y, Sueishi K, Tsuruya K, Oda Y, Kitazono T, Kiyohara Y

Kidney Int   84   373 - 380   2013.8

Prediction of cardiovascular disease mortality by proteinuria and reduced kidney function: pooled analysis of 39,000 individuals from 7 cohort stu dies in Japan Reviewed International journal

Nagata M, Ninomiya T, Kiyohara Y, Murakami Y, Irie F, Sairenchi T, Miura K, Okamura T, Ueshima H

Am J Epidemiol   178   1 - 11   2013.7

Angiopoietin-like protein 2 is associated with chronic kidney disease in a general Japanese population Reviewed International journal

Usui T, Ninomiya T, Nagata M, Takahashi O, Doi Y, Hata J, Fukuhara M, Kitazono T, Oike Y, Kiyohara Y

Circ J   77   2311 - 2317   2013.6

White-coat and masked hypertension are associated with carotid atherosclerosis in a general population: the Hisayama Study Reviewed International journal

Fukuhara M, Arima H, Ninomiya T, Hata J, Hirakawa Y, Doi Y, Yonemoto K, Mukai N, Nagata M, Ikeda F, Matsumura K, Kitazono T, Kiyohara Y

Stroke   44   1512 - 1517   2013.6

Temporal trends in sudden unexpected death in a general population: the Hisayama Study Reviewed International journal

Nagata M, Ninomiya T, Doi Y, Hata J, Ikeda F, Mukai N, Tsuruya K, Oda Y, Kitazono T, Kiyohara Y

Am Heart J   165   932 - 938   2013.6

The global cardiovascular risk transition: associations of four metabolic risk factors with national income, urbanization, and Western diet in 1980 and 2008. Invited Reviewed International journal

Danaei G, Singh GM, Paciorek CJ, Lin JK, Cowan MJ, Finucane MM, Farzadfar F, Stevens GA, Riley LM, Lu Y, Rao M, Ezzati M; Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group(Ninomiya T)

Circulation   127   1493 - 1502   2013.4

Japan Renal Biopsy Registry and Japan Kidney Disease Registry: Committee Report for 2009 and 2010. Invited Reviewed International journal

Sugiyama H, Yokoyama H, Sato H, Saito T, Kohda Y, Nishi S, Tsuruya K, Kiyomoto H, Iida H, Sasaki T, Higuchi M, Hattori M, Oka K, Kagami S, Kawamura T, Takeda T, Hataya H, Fukasawa Y, Fukatsu A, Morozumi K, Yoshikawa N, Shimizu A, Kitamura H, Yuzawa Y, Matsuo S, Kiyohara Y, Joh K, Nagata M, Taguchi T, Makino H,Committee for Standardization of Renal Pathological Diagnosis; Committee for Kidney Disease Registry(Ninomiya T); Japanese Society of Nephrology

Clin Exp Nephrol 17: 155-173, 2013   17   155 - 173   2013.4

Association Study of 71 European Crohn's Disease Susceptibility Loci in a Japanese Population. Invited Reviewed International journal

Hirano A, Yamazaki K, Umeno J, Ashikawa K, Aoki M, Matsumoto T, Nakamura S, Ninomiya T, Matsui T, Hirai F, Kawaguchi T, Takazoe M, Tanaka H, Motoya S, Kiyohara Y, Kitazono T, Nakamura Y, Kamatani N, Kubo M

Inflamm Bowel Dis 19: 526-533, 2013   19   526 - 533   2013.3

ADVANCE Collaborative Group: Effects of the endpoint adjudication process on the results of a randomised controlled trial: the ADVANCE trial. Invited Reviewed International journal

Hata J, Arima H, Zoungas S, Fulcher G, Pollock C, Adams M, Watson J, Joshi R, Kengne AP, Ninomiya T, Anderson C, Woodward M, Patel A, Mancia G, Poulter N, MacMahon S, Chalmers J, Neal B

PLoS One 8: e55807, 2013   8   e55807   2013.2

Impact of eating rate on obesity and cardiovascular risk factors according to glucose tolerance status: the Fukuoka Diabetes Registry and the Hisayama Study. Invited Reviewed International journal

Ohkuma T, Fujii H, Iwase M, Kikuchi Y, Ogata S, Idewaki Y, Ide H, Doi Y, Hirakawa Y, Mukai N, Ninomiya T, Uchida K, Nakamura U, Sasaki S, Kiyohara Y, Kitazono T

Diabetologia   56   70 - 77   2013.1

Angiopoietin-Like Protein 2 and Risk of Type 2 Diabetes in a General Japanese Population: the Hisayama Study. Invited Reviewed International journal

Doi Y, Ninomiya T, Hirakawa Y, Takahashi O, Mukai N, Hata J, Iwase M, Kitazono T, Oike Y, Kiyohara Y

Diabetes Care   36   98 - 100   2013.1

Committee for the Standardization of Renal Pathological Diagnosis and for Renal Biopsy and Disease Registry of the Japanese Society of Nephrology(Ninomiya T), and the Progressive Renal Disease Research of the Ministry of Health, Labour and Welfare of Japan: Renal disease in the elderly and the very elderly Japanese: analysis of the Japan Renal Biopsy Registry (J-RBR). Invited Reviewed International journal

Yokoyama H, Sugiyama H, Sato H, Taguchi T, Nagata M, Matsuo S, Makino H, Watanabe T, Saito T, Kiyohara Y, Nishi S, Iida H, Morozumi K, Fukatsu A, Sasaki T, Tsuruya K, Kohda Y, Higuchi M, Kiyomoto H, Goto S, Hattori M, Hataya H, Kagami S, Yoshikawa N, Fukasawa Y, Ueda Y, Kitamura H, Shimizu A, Oka K, Nakagawa N, Ito T, Uchida S, Furuichi K, Nakaya I, Umemura S, Hiromura K, Yoshimura M, Hirawa N, Shigematsu T, Fukagawa M, Hiramatsu M, Terada Y, Uemura O, Kawata T, Matsunaga A, Kuroki A, Mori Y, Mitsuiki K, Yoshida H

Clin Exp Nephrol   16   903 - 920   2012.12

the ADVANCE Collaborative Group: Prediction of kidney-related outcomes in patients with type 2 diabetes. Invited Reviewed International journal

Jardine MJ, Hata J, Woodward M, Perkovic V, Ninomiya T, Arima H, Zoungas S, Cass A, Patel A, Marre M, Mancia G, Mogensen CE, Poulter N, Chalmers J

Am J Kidney Dis   60   770 - 778   2012.11

C-reactive protein, fibrinogen, and cardiovascular disease prediction. Invited Reviewed International journal

N Engl J Med   367   1310 - 1320   2012.10

Antioxidants for chronic kidney disease. Invited Reviewed International journal

Jun M, Venkataraman V, Razavian M, Cooper B, Zoungas S, Ninomiya T, Webster AC, Perkovic V

Cochrane Database Syst Rev   10   2012.10

Resting heart rate and the risk of death and cardiovascular complications in patients with type 2 diabetes mellitus. Invited Reviewed International journal

Hillis GS, Woodward M, Rodgers A, Chow CK, Li Q, Zoungas S, Patel A, Webster R, Batty GD, Ninomiya T, Mancia G, Poulter NR, Chalmers J

Diabetologia   55   1283 - 1290   2012.10

Prevalence and risk factors for myopic retinopathy in a Japanese population: the Hisayama Study. Invited Reviewed International journal

Asakuma T, Yasuda M, Ninomiya T, Noda Y, Arakawa S, Hashimoto S, Ohno-Matsui K, Kiyohara Y, Ishibashi T

Ophthalmology   119   1760 - 1765   2012.9

Effects of intensive blood pressure lowering on cardiovascular and renal outcomes: a systematic review and meta-analysis. Invited Reviewed International journal

Lv J, Neal B, Ehteshami P, Ninomiya T, Woodward M, Rodgers A, Wang H, Macmahon S, Turnbull F, Hillis G, Chalmers J, Perkovic V

PLoS Med   9   e1001293   2012.8

Adult height and the risk of cause-specific death and vascular morbidity in 1 million people: individual participant meta-analysis. Invited Reviewed International journal

Emerging Risk Factors Collaboration(Ninomiya T)

Int J Epidemiol   41   1419 - 1433   2012.7

Insulin resistance and the development of cardiovascular disease in a Japanese community: the Hisayama Study. Invited Reviewed International journal

Gotoh S, Doi Y, Hata J, Ninomiya T, Mukai N, Fukuhara M, Kamouchi M, Kitazono T, Kiyohara Y

J Atheroscler Thromb   19   977 - 985   2012.7

Putative episodes of T-cell-mediated rejection in patients with sustained BK viruria but no viremia. Invited Reviewed International journal

Masutani K, Shapiro R, Basu A, Tan H, Ninomiya T, Randhawa P

Transplantation   94   43 - 49   2012.7

The effect of folic acid based homocysteine lowering on cardiovascular events in people with kidney disease: systematic review and meta-analysis. Invited Reviewed International journal

Jardine MJ, Kang A, Zoungas S, Navaneethan SD, Ninomiya T, Nigwekar SU, Gallagher MP, Cass A, Strippoli G, Perkovic V

BMJ   344   3533   2012.6

Optimal cutoff value of the serum pepsinogen level for prediction of gastric cancer incidence: the Hisayama Study Reviewed International journal

Shikata K, Ninomiya T, Yonemoto K, Ikeda F, Hata J, Doi Y, Fukuhara M, Matsumoto T, Iida M, Kitazono T, Kiyohara Y

Scand J Gastroenterol   47   2012.6

Impact of lower range of prehypertension on cardiovascular events in a general population: the Hisayama Study Reviewed International journal

Fukuhara M, Arima H, Ninomiya T, Hata J, Yonemoto K, Doi Y, Hirakawa Y, Matsumura K, Kitazono T, Kiyohara Y

J Hypertens   30   2012.5

Association of HbA(1c) levels with vascular complications and death in patients with type 2 diabetes: evidence of glycaemic thresholds. Reviewed International journal

Zoungas S, Chalmers J, Ninomiya T, Li Q, Cooper ME, Colagiuri S, Fulcher G, de Galan BE, Harrap S, Hamet P, Heller S, Macmahon S, Marre M, Poulter N, Travert F, Patel A, Neal B, Woodward M; for the ADVANCE Collaborative Group

Diabetologia   55   2012.3

White blood cell count and risk of gastric cancer incidence in a general Japanese population: the Hisayama study. Reviewed International journal

Iida M, Ikeda F, Ninomiya T, Yonemoto K, Doi Y, Hata J, Matsumoto T, Iida M, Kiyohara Y

Am J Epidemiol   175   2012.3

Cut-off values of fasting and post-load plasma glucose and HbA1c for predicting Type 2 diabetes in community-dwelling Japanese subjects: the Hisayama Study Reviewed International journal

Mukai N, Doi Y, Ninomiya T, Hata J, Hirakawa Y, Fukuhara M, Iwase M, Kiyohara Y

Diabet Med   29   2012.1

Two risk score models for 2 diabetes in Japan. Reviewed International journal

Doi Y, Ninomiya T, Hata J, Hirakawa Y, Mukai N, Iwase M, Kiyohara Y

Diabet Med   29   2012.1

Lower estimated glomerular filtration rate and higher albuminuria are associated with mortality and end-stage renal disease. A collaborative meta-analysis of kidney disease population cohorts. Invited Reviewed International journal

Chronic Kidney Disease Prognosis Consortium(Ninomiya T), Astor BC, Matsushita K, Gansevoort RT, van der Velde M, Woodward M, Levey AS, de Jong PE, Coresh J, El-Nahas M, Eckardt KU, Kasiske BL, Wright J, Appel L, Greene T, Levin A, Djurdjev O, Wheeler DC, Landray MJ, Townend JN, Emberson J, Clark LE, Macleod A, Marks A, Ali T, Fluck N, Prescott G, Smith DH, Weinstein JR, Johnson ES, Thorp ML, Wetzels JF, Blankestijn PJ, van Zuilen AD, Menon V, Sarnak M, Beck G, Kronenberg F, Kollerits B, Froissart M, Stengel B, Metzger M, Remuzzi G, Ruggenenti P, Perna A, Heerspink HJ, Brenner B, de Zeeuw D, Rossing P, Parving HH, Auguste P, Veldhuis K, Wang Y, Camarata L, Thomas B, Manley T

Kidney Int   79   1331 - 1340   2011.12

Validation study of oxford classification of IgA nephropathy: the significance of extracapillary proliferation Reviewed International journal

Katafuchi R, Ninomiya T, Nagata M, Mitsuiki K, Hirakata H

Clin J Am Soc Nephrol   6   2011.12

N-Terminal Pro-Brain Natriuretic Peptide and Risk of Cardiovascular Events in a Japanese Community: The Hisayama Study. Reviewed International journal

Doi Y, Ninomiya T, Hata J, Hirakawa Y, Mukai N, Ikeda F, Fukuhara M, Iwase M, Kiyohara Y

Arterioscler Thromb Vasc Biol   31   2011.12

Association of Alzheimer disease pathology with abnormal lipid metabolism: the Hisayama Study. Invited Reviewed International journal

Matsuzaki T, Sasaki K, Hata J, Hirakawa Y, Fujimi K, Ninomiya T, Suzuki SO, Kanba S, Kiyohara Y, Iwaki T

Neurology   77   1068 - 1075   2011.9

Glucose tolerance status and risk of dementia in the community: The Hisayama Study Reviewed International journal

Ohara T, Doi Y, Ninomiya T, Hirakawa Y, Hata J, Iwaki T, Kanba S, Kiyohara Y

Neurology   77   2011.9

Japan Renal Biopsy Registry: the first nationwide, web-based, and prospective registry system of renal biopsies in Japan. Invited Reviewed International journal

Sugiyama H, Yokoyama H, Sato H, Saito T, Kohda Y, Nishi S, Tsuruya K, Kiyomoto H, Iida H, Sasaki T, Higuchi M, Hattori M, Oka K, Kagami S, Nagata M, Kawamura T, Honda M, Fukasawa Y, Fukatsu A, Morozumi K, Yoshikawa N, Yuzawa Y, Matsuo S, Kiyohara Y, Joh K, Taguchi T, Makino H; Committee for Standardization of Renal Pathological Diagnosis and Working Group for Renal Biopsy Database, Japanese Society of Nephrology, Tokyo, Japan (Ninomiya T).

Clin Exp Nephrol   15   493 - 503   2011.8

Nine-year incidence and risk factors for retinal vein occlusion in a general Japanese population: the Hisayama Study. Invited Reviewed International journal

Arakawa S, Yasuda M, Nagata M, Ninomiya T, Hirakawa Y, Doi Y, Kiyohara Y, Ishibashi T

Invest Ophthalmol Vis Sci   52   5905 - 5909   2011.7

High serum bilirubin levels and diabetic retinopathy: the Hisayama Study. Invited Reviewed International journal

Yasuda M, Kiyohara Y, Wang JJ, Arakawa S, Yonemoto K, Doi Y, Ninomiya T, Ishibashi T

Ophthalmology   118   1423 - 1428   2011.6

Dietary vitamin A intake and incidence of gastric cancer in a general Japanese population: the Hisayama Study. Invited Reviewed International journal

Miyazaki M, Doi Y, Ikeda F, Ninomiya T, Hata J, Uchida K, Shirota T, Matsumoto T, Iida M, Kiyohara Y

Gastric Cancer   15   162 - 169   2011.4

Separate and combined associations of body-mass index and abdominal adiposity with cardiovascular disease: collaborative analysis of 58 prospective studies. Invited Reviewed International journal

Wormser D, Kaptoge S, Di Angelantonio E, Wood AM, Pennells L, Thompson A, Sarwar N, Kizer JR, Lawlor DA, Nordestgaard BG, Ridker P, Salomaa V, Stevens J, Woodward M, Sattar N, Collins R, Thompson SG, Whitlock G, Danesh J; the Emerging Risk Factors Collaboration(Ninomiya T)

Lancet   377   1085 - 1095   2011.3

Diabetes mellitus, fasting glucose, and risk of cause-specific death. Invited Reviewed International journal

N Engl J Med   364   829 - 841   2011.3

National, regional, and global trends in systolic blood pressure since 1980: systematic analysis of health examination surveys and epidemiological studies with 786 country-years and 5.4 million participants. Invited Reviewed International journal

Danaei G, Finucane MM, Lin JK, Singh GM, Paciorek CJ, Cowan MJ, Farzadfar F, Stevens GA, Lim SS, Riley LM, Ezzati M; Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group (Blood Pressure) (Ninomiya T)

Lancet   377   568 - 577   2011.2

逆浸透装置膜圧の処理水エンドトキシン濃度に及ぼす影響. Invited Reviewed International journal

小野 健一, 久保 充明, 利田 忠陽, 二宮 利治, 柏木 稔, 平方 恵理子, 金井 英俊, 平方 秀樹, 藤見 惺

日本透析医学会雑誌   35   281 - 286   2002.5

Treatment of hepatic encephalopathy by retrograde transcaval coil embolization of an ileal vein-to-right gonadal vein portosystemic shunt. Reviewed International journal

Nishie A, Yoshimitsu K, Honda H, Kaneko K, Kuroiwa T, Fukuya T, Irie H, Ninomiya T, Yoshimitsu T, Hirakata H, Okuda S, Masuda K.

Cardiovasc Intervent Radiol   20 ( 3 )   222 - 224   1997.1

Chapter6. Epidemiology of dementia in a community: the Hisayama Study.

Ninomiya T

Health Issues and Care System for the Elderly, Washio M, Kiyohara C(editors),Springer  2019.2 

Diet and nutrition in dementia and cognitive decline: Japanese perspective on dietary patterns and risk of dementia

Ninomiya T, Ozawa M（ Role： Joint author）

2015.1 

Brain, Stroke and Kidney (Contributions to Nephrology, Vol. 179): Risk of stroke in kidney disease

Ninomiya T（ Role： Sole author）

2013.1 

慢性腎臓病における心血管疾患. 4）脳卒中. 心腎相関の病態理解と診療.

永田　雅治, 二宮　利治, 清原　裕,（ Role： Edit）

2008.1 

心血管病変：慢性腎機能障害における心血管病発症.

二宮　利治, 平方　秀樹, 清原　裕.（ Role： Edit）

2006.1 

第1章 高血圧症の概念･定義 疫学 －日本人の高血圧症の特徴－.

二宮　利治, 清原　裕.（ Role： Edit）

2004.1 

日本におけるCKDの疫学. 慢性腎臓病と心血管病：久山町研究及びJALS統合研究. Invited

二宮　利治, 清原　裕.

第52回日本腎臓学会学術総会.  2009.6 

The fixed combination of perindopril and indapamide has a greater effect on cardiovascular outcomes in patients with type 2 diabetes and albuminuria. International conference

Ninomiya T, Heerspink HJL, Perkovic V, Zoungas S, Patel A, Grobbee D, Harrap S, Heller S, Cooper M, MacMahon S, Mancia G, Marre M, Neal B, Woodward M, Chalmers J.

ISN Nexus Symposium Kyoto 2010  2010.4 

認知機能における25-OHビタミンDの関連：海士町研究．<ポスター>

古和久典、深田育代、中野俊也、岸　真文、和田健二、二宮利治、中島健二

第42回日本認知症学会学術集会  2024.11 

地域高齢住民における歯数とサルコペニア発症との関連：久山町研究．

友岡祥子、柏﨑晴彦、二宮利治

日本老年歯科医学会第35回学術大会  2024.6 

生活習慣と認知症．

二宮利治

若宮シニアクラブ第3回健康づくりセミナー  2024.6 

<シンポジウム30>老年医学における大規模データベースの活用．

<座長>寳澤　篤、二宮利治

第66回日本老年医学会学術集会  2024.6 

地域循環器コホートからの情報発信<会長特別企画2>九州の循環器コホートからの情報発信．

二宮利治

第136回日本循環器学会九州地方会  2024.6 

地域認知症コホート研究：久山町研究における最近の知見<会長企画シンポジウム1>コホート研究から健康長寿の鍵を紐解く．

二宮利治

第24回日本抗加齢医学会総会  2024.5 

地域疫学研究の実際．

二宮利治

九州大学大学院医療経営・管理学専攻講義  2024.5 

食事と運動機能が認知症発症リスクに及ぼす影響：久山町研究．

二宮利治

第78回日本栄養・食糧学会大会  2024.5 

地域認知症コホート研究の最近知見：久山町研究．

二宮利治

第25回九州老年期認知症研究会（Web講演会）  2024.5 

心電図P波指標と心房細動発症、組織的線維化との関連：久山町研究．

二宮利治

COI-NEXT第26回弘前大学健康未来イノベーション研究機構運営会議（健康未来共創会議）  2024.5 

血清asngiopoietin-like protein 2 (ANGPTL2)濃度と死因別死亡の関連：久山町研究．

秦　淳、坂田智子、古田芳彦、大石絵美、本田貴紀、柴田舞欧、北園孝成、尾池雄一、二宮利治

第60回日本循環器予防学会学術集会  2024.5 

<シンポジウム1>古くて新しい循環器疾患のマーカー．

二宮利治

第60回日本循環器予防学会学術集会  2024.5  日本循環器予防学会学術集会

地域住民を対象とした認知症の疫学調査．

二宮利治

九州大学歯学部歯科全身管理学特別講義  2024.5 

バイオバンクとデータ解析のワークショップ．

二宮利治

2024.4 

研究デザインや基本的な統計解析の手法について学ぼう．

二宮利治

第6回初学者のためのCKD臨床研究セミナー＠九州大学  2024.3 

地域住民における角膜ヒステリシスと緑内障の関連：久山町研究．

藤原康太、上田瑛美、橋本左和子、中村　駿、秦　淳、中野聡子、村上祐介、久保田敏昭、吉冨健志、二宮利治、園田康平

第127回日本眼科学会総会  2023.4 

地域住民における高血圧の有病率・管理状況および心血管病発症リスクの時代的推移：久山町研究．

秦　淳、大石絵美、二宮利治

第45回日本高血圧学会総会  2023.9 

血漿認知症バイオマーカーと認知症発症の関係：地域前向きコホート研究の成績より．

小原知之、秦　淳、徳田隆彦、本田貴紀、柴田舞欧、中路重之、前田哲也、小野賢二郎、三村　將、中島健二、伊賀淳一、竹林　実、二宮利治

第38回日本老年精神医学会秋季大会  2023.10 

疫学．

二宮利治

令和健康科学大学講義  2023.11 

認知症の血漿バイオマーカーと認知症発症との関連<シンポジウム15>認知症バイオマーカー研究の最新知見．

小原知之、二宮利治

第42回日本認知症学会学術集会  2023.11 

地域疫学研究を基盤とした脳梗塞発症のリスク予測：久山町研究<シンポジウム9>データベース研究の新展開．

秦　淳、二宮利治

第66回日本脳循環代謝学会学術集会  2023.11 

久山町コホートからみた生活習慣病・生活習慣と脳画像との関連<シンポジウム3>地域コホート研究からみた生活習慣・生活習慣病と脳画像との関連．

小原知之、二宮利治

第42回日本認知症学会学術集会  2023.11 

古和久典、深田育代、中野俊也、岸　真文、和田健二、二宮利治、中島健二

認知機能における25-CHビタミンDの関連：海士町研究．<ポスター>

第42回日本認知症学会学術集会  2023.11 

陳　俐穎、舘脇康子、Benjamin Thyreau、内田和宏、壹岐ひかり、中瀬泰然、中路重之、前田哲也、野口・篠原もえ子、三村　將、中島健二、伊賀淳一、竹林　実、二宮利治、瀧　靖之

白質病変の定量化による日本人大規模高齢者集団の食事パターンと認知症に関する研究．<ポスター>

第42回日本認知症学会学術集会  2023.11 

水野裕理、本田裕之、二宮利治、磯部紀子、村井弘之

アルツハイマー型認知症の脳内におけるトランスサイレチンの発現様式の検討．<ポスター>

第42回日本認知症学会学術集会  2023.11 

地域高齢住民における認知症有病率の時代的変化：久山町研究．

小原知之、二宮利治

第42回日本認知症学会学術集会  2023.11 

地域住民における尿中神経伝達物質と抑うつ症状発症の関連：久山町研究．<ポスター>

柴田舞欧、平林直樹、細井昌子、中村侑里、秦　淳、須藤信行、二宮利治

第27回日本心療内科学会総会・学術大会  2023.12 

動脈硬化性疾患の疫学研究：久山町研究の最近の知見より．

二宮利治

第54回福岡東脳卒中の地域連携の夕べ  2024.2 

地域糖尿病コホート研究・久山町研究．

二宮利治

糖尿病治療を考える会、福岡市、2024.2  2024.2 

地域高齢者住民を対象とした大規模認知症コホート研究（JPSC-AD研究）の取組．

二宮利治

第2回医療・健康ユニットシンポジウム  2024.3 

認知症予防における筋力・運動機能維持の重要性．

二宮利治

平尾公民館平尾大学  2024.3 

日本人地域住民における座位行動と糖代謝マーカーの経時変化および糖尿病発症の関連：久山町研究． International conference

津田　晋、本田貴紀、東岡真由、秦　淳、中野敏昭、北園孝成、二宮利治

第34回日本疫学会学術総会  2024.2 

地域住民における健康管理への取組～久山町研究～．

二宮利治

Oriental land Friendship Society九州研修  2024.1 

久山町研究からの最近の知見．

二宮利治

2024.1 

全国の一般地域住民における最近の循環器疾患発症率．<ポスター>

門田　文、大久保孝義、原田亜紀子、高島直敬、有馬久富、二宮利治、秦　淳、寶澤　篤、中村幸志、東山　綾、大澤正樹、久松隆史、鳥居さゆ希、岡見雪子、近藤慶子、宮本恵宏、岡村智教、上島弘嗣、岡山　明、三浦克之

第34回日本疫学会学術総会  2024.2 

地域住民における社会的・情緒的孤独感と慢性疼痛の関連：久山町研究．

柴田舞欧、平林直樹、細井昌子、安野広三、秦　淳、須藤信行、二宮利治

第30回日本未病学会学術総会  2023.12 

日本人地域住民における教育年数と眼軸長および開放隅角緑内障の関連：久山町研究．

中村　駿、上田瑛美、藤原康太、柴田舞欧、安田美穂、本田貴紀、橋本左和子、秦　淳、二宮利治、園田康平

第5回日本近視学会総会  2023.5 

臨床・疫学研究の進め方．

二宮利治

岩手医科大学 講演会  2023.12 

大規模認知症コホート研究（JPSC-AD）について．

二宮利治

やはば脳とカラダのいきいき健康事業、いきいき記念講演会2023  2023.12 

高齢者保健．

二宮利治

令和健康科学大学講義  2023.12 

感染症．

二宮利治

令和健康科学大学講義  2023.12 

認知症発症のリスク低減における生活習慣病予防および運動機能維持の重要性：久山町研究．<特別講演>

二宮利治

大牟田臨床認知症研究会第34回特別講演会  2023.12 

久山町研究のこれから<記念シンポジウム>久山町研究の過去、未来．

二宮利治

九州大学医学部120周年を祝う会  2023.12 

日本人地域住民におけるサルコペニアの疫学：久山町研究<シンポジウム9>筋肉・サルコペニア肥満．

秦　淳、二宮利治

第44回日本肥満学会・第41回日本肥満症治療学会学術集会  2023.11 

動脈硬化性疾患のリスク評価：久山町研究．

二宮利治

宗像内科医会学術講演会  2023.9