Secular trends in cardiovascular disease and its risk factors in Japanese: half-century data from the Hisayama Study (1961-2009) Reviewed International journal

Hata J, Ninomiya T, Hirakawa Y, Nagata M, Mukai N, Gotoh S, Fukuhara M, Ikeda F, Shikata K, Yoshida D, Yonemoto K, Kamouchi M, Kitazono T, Kiyohara Y.

Circulation   2013.9

Effects of visit-to-visit variability in systolic blood pressure on macrovascular and microvascular complications in patients with type 2 diabetes mellitus: the ADVANCE trial Reviewed International journal

Hata J, Arima H, Rothwell PM, Woodward M, Zoungas S, Anderson C, Patel A, Neal B, Glasziou P, Hamet P, Mancia G, Poulter N, Williams B, Macmahon S, Chalmers J; ADVANCE Collaborative Group.

Circulation   2013.9

Effects of the endpoint adjudication process on the results of a randomised controlled trial: the ADVANCE trial Reviewed International journal

Hata J, Arima H, Zoungas S, Fulcher G, Pollock C, Adams M, Watson J, Joshi R, Kengne AP, Ninomiya T, Anderson C, Woodward M, Patel A, Mancia G, Poulter N, MacMahon S, Chalmers J, Neal B; ADVANCE Collaborative Group.

PLoS One   2013.1

Combined effects of smoking and hypercholesterolemia on the risk of stroke and coronary heart disease in Japanese: the Hisayama Study Reviewed International journal

Hata J, Doi Y, Ninomiya T, Fukuhara M, Ikeda F, Mukai N, Hirakawa Y, Kitazono T, Kiyohara Y.

Cerebrovasc Dis   2011.1

The effect of metabolic syndrome defined by various criteria on the development of ischemic stroke subtypes in a general Japanese population Reviewed International journal

Hata J, Doi Y, Ninomiya T, Tanizaki Y, Yonemoto K, Fukuhara M, Kubo M, Kitazono T, Iida M, Kiyohara Y.

Atherosclerosis   2010.5

Secular trends in the incidence of and risk factors for ischemic stroke and its subtypes in Japanese population Reviewed International journal

Kubo M, Hata J, Doi Y, Tanizaki Y, Iida M, Kiyohara Y.

Circulation   2008.12

Functional SNP in an Sp1-binding site of AGTRL1 gene is associated with susceptibility to brain infarction Reviewed International journal

Hata J, Matsuda K, Ninomiya T, Yonemoto K, Matsushita T, Ohnishi Y, Saito S, Kitazono T, Ibayashi S, Iida M, Kiyohara Y, Nakamura Y, Kubo M.

Hum Mol Genet   2007.3

Ten year recurrence after first ever stroke in a Japanese community: the Hisayama Study Reviewed International journal

Hata J, Tanizaki Y, Kiyohara Y, Kato I, Kubo M, Tanaka K, Okubo K, Nakamura H, Oishi Y, Ibayashi S, Iida M.

J Neurol Neurosurg Psychiatry   2005.3

Autonomic nervous system function assessed by heart rate variability and the presence of symptoms affecting activities of daily living in community-dwelling residents with chronic pain: The Hisayama Study. International journal

Yuri Nakamura, Mao Shibata, Yukiko Morisaki, Naoki Hirabayashi, Mayu Higashioka, Jun Hata, Masako Hosoi, Nobuyuki Sudo, Ken Yamaura, Toshiharu Ninomiya

European journal of pain (London, England)   28 ( 5 )   831 - 844   2024.5

Serum high-sensitivity C-reactive protein and dementia in a community-dwelling Japanese older population (JPSC-AD) Reviewed

Tachibana A, Iga JI, Ozaki T, Yoshida T, Yoshino Y, Shimizu H, Mori T, Furuta Y, Shibata M, Ohara T, Hata J, Taki Y, Mikami T, Maeda T, Ono K, Mimura M, Nakashima K, Takebayashi M, Ninomiya T, Ueno SI; JPSC-AD study group

Sci Rep   14 ( 1 )   7374   2024.3

Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults Reviewed International coauthorship

NCD Risk Factor Collaboration (NCD-RisC)

Lancet   403 ( 10431 )   1027 - 1050   2024.3

Association between corneal hysteresis and glaucoma in a Japanese population: the Hisayama Study. International journal

Kohta Fujiwara, Emi Ueda, Jun Hata, Satoko Nakano, Sawako Hashimoto, Shun Nakamura, Yusuke Murakami, Toshiaki Kubota, Takeshi Yoshitomi, Toshiharu Ninomiya, Koh-Hei Sonoda

The British journal of ophthalmology   2024.3

Association between Vascular Calcification and Intraplaque Hemorrhage in Coronary Atherosclerosis from Autopsy: The Hisayama Study.

Toshiaki Nakano, Hiromasa Kitamura, Jun Hata, Kenji Maki, Yoshinao Oda, Takanari Kitazono, Toshiharu Ninomiya

Journal of atherosclerosis and thrombosis   31 ( 8 )   1225 - 1237   2024.3   （ ISSN:13403478 eISSN:18803873 ）

Longitudinal association of sedentary time with diabetes mellitus and markers of glucose metabolism in middle-aged and older adults: the Hisayama Study Reviewed

Tsuda S, Honda T, Higashioka M, Hata J, Nakano T, Kitazono T, Ninomiya T

J Diabetes Investig   15 ( 2 )   245 - 246   2024.2

Serum lipopolysaccharide-binding protein levels and the incidence of metabolic syndrome in a general Japanese population: the Hisayama Study Reviewed

Tomooka S, Oishi E, Asada M, Sakata S, Hata J, Chen S, Honda T, Suzuki K, Watanabe H, Murayama N, Wada N, Kitazono T, Ninomiya T.

J Epidemiol   2024.1

Late-life high blood pressure and enlarged perivascular spaces in the putaminal regions of community-dwelling Japanese plder persons. Reviewed International journal

Tachibana A, Iga JI, Tatewaki Y, Thyreau B, Chen H, Ozaki T, Yoshida T, Yoshino Y, Shimizu H, Mori T, Furuta Y, Shibata M, Ohara T, Hata J, Taki Y, Nakaji S, Maeda T, Ono K, Mimura M, Nakashima K, Takebayashi M, Ninomiya T, Ueno SI; JPSC-AD study group.

J Geriatr Psychiatry Neurol   37 ( 1 )   61 - 72   2024.1

Development and validation of a risk pediction model for atherosclerotic cardiovascular disease in Japanese adults: the Hisayama Study Reviewed

Honda T, Chen S, Hata J, Yoshida D, Hirakawa Y, Furuta Y, Shibata M, Sakata S, Kitazono T, Ninomiya T

J Atheroscler Thromb   30 ( 12 )   1966 - 1967   2023.12

Global variation in diabetes diagnosis and prevalence based on fasting glucose and hemoglobin A1c

Nature Medicine   2023.11

Life expectancy associated with different ages at diagnosis of type 2 diabetes in high-income countries: 23 million person-years of observation Reviewed International coauthorship

Emerging Risk Factors Collaboration

Lancet Diabetes Endocrinol   11 ( 10 )   731 - 742   2023.10

Gender and age influence the association between gait speed and mild cognitive impairment in community‐dwelling Japanese older adults: from the Japan Prospective Studies Collaboration for Ageing and Dementia (JPSC‐AD) Reviewed International journal

Shogyoku Bun, Kouta Suzuki, Hidehito Niimura, Ryo Shikimoto, Hisashi Kida, Mao Shibata, Takanori Honda, Tomoyuki Ohara, Jun Hata, Shigeyuki Nakaji, Tetsuya Maeda, Kenjiro Ono, Kenji Nakashima, Jun‐ichi Iga, Minoru Takebayashi, Toshiharu Ninomiya, Masaru Mimura

2023.8

Association between frequency of social contact and brain atrophy in community-dwelling older people without dementia: the JPSC-AD Study. Reviewed International journal

Naoki Hirabayashi, Takanori Honda, Jun Hata, Yoshihiko Furuta, Mao Shibata, Tomoyuki Ohara, Yasuko Tatewaki, Yasuyuki Taki, Shigeyuki Nakaji, Tetsuya Maeda, Kenjiro Ono, Masaru Mimura, Kenji Nakashima, Jun-Ichi Iga, Minoru Takebayashi, Toshiharu Ninomiya

Neurology   2023.7

Changes in the eicosapentaenoic acid to arachidonic acid ratio in serum over 10 years in a Japanese community: the Hisayama Study Reviewed

Honda T, Chen S, Hata J, Shibata M, Furuta Y, Oishi E, Sakata S, Kitazono T, Ninomiya T.

J Atheroscler Thromb   2023.6

Serum Mac-2 binding protein glycosylation isomer concentrations are associated with incidence of type 2 diabetes Reviewed International journal

Higashioka M, Hirakawa Y, Hata J, Honda T, Sakata S, Shibata M, Kitazono T, Osawa H, Ninomiya T.

J Clin Endocrinol Metab   2023.6

Association between choroidal thickness and myopic maculopathy in a Japanese population: the Hisayama Study Reviewed International journal

Emi Ueda, Miho Yasuda, Kohta Fujiwara, Sawako Hashimoto, Takanori Honda, Shun Nakamura, Jun Hata, Toshiharu Ninomiya, Koh-Hei Sonoda

Ophthalmology Science   100350 - 100350   2023.6

Association of white matter lesions and brain atrophy with the development of dementia in a community: the Hisayama Study Reviewed

Nakazawa T, Ohara T, Hirabayashi N, Furuta Y, Hata J, Shibata M, Honda T, Kitazono T, Nakao T, Ninomiya T.

Psychiatry Clin Neurosci   2023.6

CKD, Brain Atrophy, and White Matter Lesion Volume: The Japan Prospective Studies Collaboration for Aging and Dementia. International journal

Kenji Maki, Tomoyuki Ohara, Jun Hata, Mao Shibata, Naoki Hirabayashi, Takanori Honda, Satoko Sakata, Yoshihiko Furuta, Masato Akiyama, Keisuke Yamasaki, Yasuko Tatewaki, Yasuyuki Taki, Takanari Kitazono, Tatsuya Mikami, Tetsuya Maeda, Kenjiro Ono, Masaru Mimura, Kenji Nakashima, Jun-Ichi Iga, Minoru Takebayashi, Toshiharu Ninomiya

Kidney medicine   5 ( 3 )   100593 - 100593   2023.3

Secular trends in the prevalence, incidence, and progression of diabetic retinopathy: the Hisayama Study Reviewed International journal

Hashimoto S, Yasuda M, Fujiwara K, Ueda E, Nakamura S, Hirakawa Y, Higashioka M, Hata J, Ninomiya T, Sonoda KH.

Graefes Arch Clin Exp Ophthalmol   2023.3

Association of gait speed with regional brain volumes and risk of dementia in older Japanese: the Hisayama study Reviewed International journal

Tajimi T, Furuta Y, Hirabayashi N, Honda T, Hata J, Ohara T, Shibata M, Nakao T, Kitazono T, Nakashima Y, Ninomiya T.

Arch Gerontol Geriatr   2023.3

Diminishing benefits of urban living for children and adolescents' growth and development Reviewed International journal

NCD Risk Factor Collaboration (NCD-RisC).

Nature   2023.3

CKD, brain atrophy, and white matter lesion volume: the Japan Prospective Studies Collaboration for Aging and Dementia Reviewed International journal

Maki K, Ohara T, Hata J, Shibata M, Hirabayashi N, Honda T, Sakata S, Furuta Y, Akiyama M, Yamasaki K, Tatewaki Y, Taki Y, Kitazono T, Mikami T, Maeda T, Ono K, Mimura M, Nakashima K, Iga JI, Takebayashi M, Ninomiya T; Japan Prospective Studies Collaboration for Aging and Dementia (JPSC-AD) study group.

Kidney Med   2022.12

Prevalence of glaucoma and its systemic risk factors in a general Japanese population: the Hisayama Study Reviewed International journal

Fujiwara K, Yasuda M, Hata J, Nakano S, Hashimoto S, Ueda E, Nakamura S, Murakami Y, Nakamuro T, Iwase A, Araie M, Tawara A, Kubota T, Yoshitomi T, Ninomiya T, Sonoda KH.

Transl Vis Sci Technol   2022.11

Mild-to-moderate kidney dysfunction and cardiovascular disease: observational and mendelian randomization analyses Reviewed International journal

Circulation   2022.11

Stroke genetics informs drug discovery and risk prediction across ancestries Reviewed International journal

Nature   2022.11

Day-to-day blood pressure variability and risk of incident chronic kidney disease in a general Japanese population Reviewed International journal

Sasaki T, Sakata S, Oishi E, Furuta Y, Honda T, Hata J, Tsuboi N, Kitazono T, Yokoo T, Ninomiya T.

J Am Heart Assoc   2022.10

Altruistic social activity, depressive symptoms, and brain regional gray matter volume: voxel-based morphometry analysis from 8,695 old adults Reviewed International journal

Liu Y, Zhang Y, Thyreau B, Tatewaki Y, Matsudaira I, Takano Y, Hirabayashi N, Furuta Y, Hata J, Ninomiya T, Taki Y; Japan Prospective Studies Collaboration for Aging and Dementia (JPSC-AD) Study Group.

J Gerontol A Biol Sci Med Sci   2022.9

Association of the prefrailty with global brain atrophy and white matter lesions among cognitively unimpaired older adults: the Nakajima study Reviewed International journal

Noguchi-Shinohara M, Ono K, Yuki-Nozaki S, Iwasa K, Yokogawa M, Komai K, Thyreau B, Tatewaki Y, Taki Y, Shibata M, Ohara T, Hata J, Ninomiya T, Yamada M.

Sci Rep   2022.8

Association of serum s-adenosylmethionine, s-adenosylhomocysteine, and their ratio with the risk of dementia and death in a community Reviewed International journal

Mihara A, Ohara T, Hata J, Chen S, Honda T, Tamrakar S, Isa A, Wang D, Shimizu K, Katakura Y, Yonemoto K, Nakao T, Kitazono T, Ninomiya T.

Sci Rep   2022.7

Multi‐phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations Reviewed International journal

Gerard Temprano‐Sagrera, Colleen M. Sitlani, William P. Bone, Miguel Martin‐Bornez, Benjamin F. Voight, Alanna C. Morrison, Scott M. Damrauer, Paul S. de Vries, Nicholas L. Smith, Maria Sabater‐Lleal, Abbas Dehghan, Adam S Heath, Alanna C Morrison, Alex P Reiner, Andrew Johnson, Anne Richmond, Annette Peters, Astrid van Hylckama Vlieg, Barbara McKnight, Bruce M Psaty, Caroline Hayward, Cavin Ward‐Caviness, Christopher O’Donnell, Daniel Chasman, David P Strachan, David A Tregouet, Dennis Mook‐Kanamori, Dipender Gill, Florian Thibord, Folkert W Asselbergs, Frank W.G. Leebeek, Frits R Rosendaal, Gail Davies, Georg Homuth, Gerard Temprano, Harry Campbell, Herman A Taylor, Jan Bressler, Jennifer E Huffman, Jerome I Rotter, Jie Yao, James F Wilson, Joshua C Bis, Julie M Hahn, Karl C Desch, Kerri L Wiggins, Laura M Raffield, Lawrence F Bielak, Lisa R Yanek, Marcus E Kleber, Maria Sabater‐Lleal, Martina Mueller, Maryam Kavousi, Massimo Mangino, Melissa Liu, Michael R Brown, Matthew P Conomos, Min‐A Jhun, Ming‐Huei Chen, Moniek P.M. de Maat, Nathan Pankratz, Nicholas L Smith, Patricia A Peyser, Paul Elliot, Paul S de Vries, Peng Wei, Philipp S Wild, Pierre E Morange, Pim van der Harst, Qiong Yang, Ngoc‐Quynh Le, Riccardo Marioni, Ruifang Li, Scott M Damrauer, Simon R Cox, Stella Trompet, Stephan B Felix, Uwe Völker, Weihong Tang, Wolfgang Koenig, J. Wouter Jukema, Xiuqing Guo, Sara Lindstrom, Lu Wang, Erin N Smith, William Gordon, Astrid van Hylckama Vlieg, Mariza de Andrade, Jennifer A Brody, Jack W Pattee, Jeffrey Haessler, Ben M Brumpton, Daniel I Chasman, Pierre Suchon, Ming‐Huei Chen, Constance Turman, Marine Germain, Kerri L Wiggins, James MacDonald, Sigrid K Braekkan, Sebastian M Armasu, Nathan Pankratz, Rabecca D Jackson, Jonas B Nielsen, Franco Giulianini, Marja K Puurunen, Manal Ibrahim, Susan R Heckbert, Theo K Bammler, Kelly A Frazer, Bryan M McCauley, Kent Taylor, James S Pankow, Alexander P Reiner, Maiken E Gabrielsen, Jean‐François Deleuze, Chris J O’Donnell, Jihye Kim, Barbara McKnight, Peter Kraft, John‐Bjarne Hansen, Frits R Rosendaal, John A Heit, Bruce M Psaty, Weihong Tang, Charles Kooperberg, Kristian Hveem, Paul M Ridker, Pierre‐Emmanuel Morange, Andrew D Johnson, Christopher Kabrhel, David‐Alexandre Trégouët, Nicholas L Smith, Rainer Malik, Ganesh Chauhan, Matthew Traylor, Muralidharan Sargurupremraj, Yukinori Okada, Aniket Mishra, Loes Rutten‐Jacobs, Anne‐Katrin Giese, Sander W van der Laan, Solveig Gretarsdottir, Christopher D Anderson, Michael Chong, Hieab HH Adams, Tetsuro Ago, Peter Almgren, Philippe Amouyel, Hakan Ay, Traci M Bartz, Oscar R Benavente, Steve Bevan, Giorgio B Boncoraglio, Robert D Brown, Adam S Butterworth, Caty Carrera, Cara L Carty, Daniel I Chasman, Wei‐Min Chen, John W Cole, Adolfo Correa, Ioana Cotlarciuc, Carlos Cruchaga, John Danesh, Paul IW de Bakker, Anita L DeStefano, Marcel den Hoed, Qing Duan, Stefan T Engelter, Guido J Falcone, Rebecca F Gottesman, Raji P Grewal, Vilmundur Gudnason, Stefan Gustafsson, Jeffrey Haessler, Tamara B Harris, Ahamad Hassan, Aki S Havulinna, Susan R Heckbert, Elizabeth G Holliday, George Howard, Fang‐Chi Hsu, Hyacinth I Hyacinth, M Arfan Ikram, Erik Ingelsson, Marguerite R Irvin, Xueqiu Jian, Jordi Jiménez‐Conde, Julie A Johnson, J Wouter Jukema, Masahiro Kanai, Keith L Keene, Brett M Kissela, Dawn O Kleindorfer, Charles Kooperberg, Michiaki Kubo, Leslie A Lange, Carl D Langefeld, Claudia Langenberg, Lenore J Launer, Jin‐Moo Lee, Robin Lemmens, Didier Leys, Cathryn M Lewis, Wei‐Yu Lin, Arne G Lindgren, Erik Lorentzen, Patrik K Magnusson, Jane Maguire, Ani Manichaikul, Patrick F McArdle, James F Meschia, Braxton D Mitchell, Thomas H Mosley, Michael A Nalls, Toshiharu Ninomiya, Martin J O’Donnell, Bruce M Psaty, Sara L Pulit, Kristiina Rannikmäe, Alexander P Reiner, Kathryn M Rexrode, Kenneth Rice, Stephen S Rich, Paul M Ridker, Natalia S Rost, Peter M Rothwell, Jerome I Rotter, Tatjana Rundek, Ralph L Sacco, Saori Sakaue, Michele M Sale, Veikko Salomaa, Bishwa R Sapkota, Reinhold Schmidt, Carsten O Schmidt, Ulf Schminke, Pankaj Sharma, Agnieszka Slowik, Cathie LM Sudlow, Christian Tanislav, Turgut Tatlisumak, Kent D Taylor, Vincent NS Thijs, Gudmar Thorleifsson, Unnur Thorsteinsdottir, Steffen Tiedt, Stella Trompet, Christophe Tzourio, Cornelia M van Duijn, Matthew Walters, Nicholas J Wareham, Sylvia Wassertheil‐Smoller, James G Wilson, Kerri L Wiggins, Qiong Yang, Salim Yusuf, Najaf Amin, Hugo S Aparicio, Donna K Arnett, John Attia, Alexa S Beiser, Claudine Berr, Julie E Buring, Mariana Bustamante, Valeria Caso, Yu‐Ching Cheng, Seung Hoan Choi, Ayesha Chowhan, Natalia Cullell, Jean‐François Dartigues, Hossein Delavaran, Pilar Delgado, Marcus Dörr, Gunnar Engström, Ian Ford, Wander S Gurpreet, Anders Hamsten, Laura Heitsch, Atsushi Hozawa, Laura Ibanez, Andreea Ilinca, Martin Ingelsson, Motoki Iwasaki, Rebecca D Jackson, Katarina Jood, Pekka Jousilahti, Sara Kaffashian, Lalit Kalra, Masahiro Kamouchi, Takanari Kitazono, Olafur Kjartansson, Manja Kloss, Peter J Koudstaal, Jerzy Krupinski, Daniel L Labovitz, Cathy C Laurie, Christopher R Levi, Linxin Li, Lars Lind, Cecilia M Lindgren, Vasileios Lioutas, Yong Mei Liu, Oscar L Lopez, Hirata Makoto, Nicolas Martinez‐Majander, Koichi Matsuda, Naoko Minegishi, Joan Montaner, Andrew P Morris, Elena Muiño, Martina Müller‐Nurasyid, Bo Norrving, Soichi Ogishima, Eugenio A Parati, Leema Reddy Peddareddygari, Nancy L Pedersen, Joanna Pera, Markus Perola, Alessandro Pezzini, Silvana Pileggi, Raquel Rabionet, Iolanda Riba‐Llena, Marta Ribasés, Jose R Romero, Jaume Roquer, Anthony G Rudd, Antti‐Pekka Sarin, Ralhan Sarju, Chloe Sarnowski, Makoto Sasaki, Claudia L Satizabal, Mamoru Satoh, Naveed Sattar, Norie Sawada, Gerli Sibolt, Ásgeir Sigurdsson, Albert Smith, Kenji Sobue, Carolina Soriano‐Tárraga, Tara Stanne, O Colin Stine, David J Stott, Konstantin Strauch, Takako Takai, Hideo Tanaka, Kozo Tanno, Alexander Teumer, Liisa Tomppo, Nuria P Torres‐Aguila, Emmanuel Touze, Shoichiro Tsugane, Andre G Uitterlinden, Einar M Valdimarsson, Sven J van der Lee, Henry Völzke, Kenji Wakai, David Weir, Stephen R Williams, Charles DA Wolfe, Quenna Wong, Huichun Xu, Taiki Yamaji, Dharambir K Sanghera, Olle Melander, Christina Jern, Daniel Strbian, Israel Fernandez‐Cadenas, W T Longstreth, Arndt Rolfs, Jun Hata, Daniel Woo, Jonathan Rosand, Guillaume Pare, Jemma C Hopewell, Danish Saleheen, Kari Stefansson, Bradford B Worrall, Steven J Kittner, Sudha Seshadri, Myriam Fornage, Hugh S Markus, Joanna MM Howson, Yoichiro Kamatani, Stephanie Debette, Martin Dichgans

20 ( 6 )   1331 - 1349   2022.6

Association between diabetes and gray matter atrophy patterns in a general older Japanese population: the Hisayama Study Reviewed International journal

Hirabayashi N, Hata J, Furuta Y, Ohara T, Shibata M, Hirakawa Y, Yamashita F, Yoshihara K, Kitazono T, Sudo N, Ninomiya T.

Diabetes Care   2022.6

Higher-resolution quantification of white matter hypointensities by large-scale transfer learning from 2D images on the JPSC-AD cohort Reviewed International journal

Thyreau B, Tatewaki Y, Chen L, Takano Y, Hirabayashi N, Furuta Y, Hata J, Nakaji S, Maeda T, Noguchi-Shinohara M, Mimura M, Nakashima K, Mori T, Takebayashi M, Ninomiya T, Taki Y; Japan Prospective Studies Collaboration for Aging and Dementia (JPSC-AD) Study Group.

Hum Brain Mapp   2022.5

Active commuting, commuting modes and the risk of diabetes: 14-year follow-up data from the Hisayama Study Reviewed International journal

Honda T, Hirakawa Y, Hata J, Chen S, Shibata M, Sakata S, Furuta Y, Higashioka M, Oishi E, Kitazono T, Ninomiya T.

J Diabetes Investig   2022.5

Risks of mortality and airflow limitation in Japanese with preserved ratio impaired spirometry Reviewed International journal

Washio Y, Sakata S, Fukuyama S, Honda T, Kan-O K, Shibata M, Hata J, Inoue H, Kitazono T, Matsumoto K, Ninomiya T.

Am J Respir Crit Care Med   2022.5

Yogurt product intake and reduction of tooth loss risk in a Japanese community Reviewed International journal

Ma J, Furuta M, Uchida K, Takeshita T, Kageyama S, Asakawa M, Takeuchi K, Suma S, Sakata S, Hata J, Sohn W, Ninomiya T, Yamashita Y.

J Clin Periodontol   2022.4

Association of inner retinal thickness with prevalent dementia and brain atrophy in a general older population: the Hisayama Study Reviewed International journal

Ueda E, Hirabayashi N, Ohara T, Hata J, Honda T, Fujiwara K, Furuta Y, Shibata M, Hashimoto S, Nakamura S, Nakazawa T, Nakao T, Kitazono T, Ninomiya T, Sonoda KH.

Ophthalmol Sci   2022.4

Baseline periodontal status and modifiable risk factors are associated with tooth loss over a 10-year period: estimates of population attributable risk in a Japanese community Reviewed International journal

Furuta M, Takeuchi K, Takeshita T, Shibata Y, Suma S, Kageyama S, Asakawa M, Shimazaki Y, Hata J, Ninomiya T, Yamashita Y.

J Periodontol   2022.4

Association of daily sleep duration with the incident dementia by serum soluble TREM2 in a community Reviewed International journal

Ohara T, Hata J, Tanaka M, Honda T, Yamakage H, Inoue T, Hirakawa Y, Kusakabe T, Shibata M, Kitazono T, Nakao T, Satoh-Asahara N, Ninomiya T.

J Am Geriatr Soc   2022.4

Development and validation of a risk prediction model for atherosclerotic cardiovascular disease in Japanese adults: the Hisayama Study Reviewed

Honda T, Chen S, Hata J, Yoshida D, Hirakawa Y, Furuta Y, Shibata M, Sakata S, Kitazono T, Ninomiya T.

J Atheroscler Thromb   2022.3

Long-term association of vegetable and fruit intake with risk of dementia in Japanese older adults: the Hisayama Study Reviewed International journal

Kimura Y, Yoshida D, Ohara T, Hata J, Honda T, Hirakawa Y, Shibata M, Oishi E, Sakata S, Furuta Y, Chen S, Uchida K, Nakao T, Kitazono T, Ninomiya T.

BMC Geriatr   2022.3

Association between chronic low back pain and regional brain atrophy in a Japanese older population: the Hisayama Study Reviewed International journal

Asada M, Shibata M, Hirabayashi N, Ohara T, Furuta Y, Nakazawa T, Honda T, Hata J, Hosoi M, Sudo N, Yamaura K, Ninomiya T.

Pain   2022.3

Multiple-region grey matter atrophy as a predictor for the development of dementia in a community: the Hisayama Study Reviewed International journal

Nakazawa T, Ohara T, Hirabayashi N, Furuta Y, Hata J, Shibata M, Honda T, Kitazono T, Nakao T, Ninomiya T.

J Neurol Neurosurg Psychiatry   2022.3

Changes in body weight and concurrent changes in cardiovascular risk profiles in community residents in Japan: the Hisayama Study Reviewed

Honda T, Ishida Y, Oda M, Noguchi K, Chen S, Sakata S, Oishi E, Furuta Y, Yoshida D, Hirakawa Y, Hata J, Kitazono T, Ninomiya T.

J Atheroscler Thromb   2022.2

Long-term trends in the 5-year risk of recurrent stroke over a half century in a Japanese community: the Hisayama Study Reviewed

Nakanishi Y, Furuta Y, Hata J, Yubi T, Oishi E, Sakata S, Hirakawa Y, Wakisaka Y, Ago T, Kitazono T, Ninomiya T.

J Atheroscler Thromb   2022.2

Day-by-day blood pressure variability in the subacute stage of ischemic stroke and long-term recurrence Reviewed International journal

Fukuda K, Matsuo R, Kamouchi M, Kiyuna F, Sato N, Nakamura K, Hata J, Wakisaka Y, Ago T, Imaizumi T, Kai H, Kitazono T; FSR Investigators.

Stroke   2022.1

A comparative study of site-specific distribution of aging-related tau astrogliopathy and its risk factors between Alzheimer disease and cognitive healthy brains: the Hisayama Study Reviewed International journal

Yagita K, Honda H, Ohara T, Hamasaki H, Koyama S, Noguchi H, Mihara A, Nakazawa T, Hata J, Ninomiya T, Iwaki T.

J Neuropathol Exp Neurol   2022.1

Diabetes mellitus, elevated hemoglobin A1c, and glycated albumin are associated with the presence of all-cause dementia and Alzheimer's disease: the JPSC-AD study Reviewed International journal

Noguchi-Shinohara M, Yuki-Nozaki S, Abe C, Mori A, Horimoto M, Yokogawa M, Ishida N, Suga Y, Ishizaki J, Ishimiya M, Nakamura H, Komai K, Nakamura H, Shibata M, Ohara T, Hata J, Ninomiya T, Yamada M; Japan Prospective Studies Collaboration for Aging and Dementia (JPSC-AD) Study Group.

J Alzheimers Dis   2022.1

Serum uric acid levels and nephrosclerosis in a population-based autopsy study: the Hisayama Study Reviewed International journal

Maki K, Hata J, Sakata S, Oishi E, Furuta Y, Nakano T, Oda Y, Kitazono T, Ninomiya T.

Am J Nephrol   2022.1

Midlife and late-life diabetes and sarcopenia in a general older Japanese population: the Hisayama Study Reviewed International journal

Nakamura K, Yoshida D, Honda T, Hata J, Shibata M, Hirakawa Y, Furuta Y, Kishimoto H, Ohara T, Chen S, Kitazono T, Nakashima Y, Ninomiya T.

J Diabetes Investig   2021.10

Emotional loneliness is associated with a risk of dementia in a general Japanese older population: the Hisayama Study Reviewed International journal

Shibata M, Ohara T, Hosoi M, Hata J, Yoshida D, Hirabayashi N, Morisaki Y, Nakazawa T, Mihara A, Nagata T, Oishi E, Anno K, Sudo N, Ninomiya T.

J Gerontol B Psychol Sci Soc Sci   2021.10

Development of a risk prediction model for incident hypertension in Japanese individuals: the Hisayama Study Reviewed

Oishi E, Hata J, Honda T, Sakata S, Chen S, Hirakawa Y, Yoshida D, Shibata M, Ohara T, Furuta Y, Kitazono T, Ninomiya T.

Hypertens Res   2021.9

Pathologic diabetic nephropathy in autopsied diabetic cases with normoalbuminuria from a Japanese community-based study Reviewed International journal

Sasaki T, Nakagawa K, Hata J, Hirakawa Y, Shibata M, Nakano T, Tsuboi N, Oda Y, Kitazono T, Yokoo T, Ninomiya T.

Kidney Int Rep   2021.9

Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants Reviewed International journal

NCD Risk Factor Collaboration (NCD-RisC).

Lancet   2021.9

Serum NT-proBNP levels and histopathological myocardial fibrosis in autopsied cases from a Japanese community: the Hisayama Study Reviewed International journal

Sasaki T, Izumaru K, Hata J, Sakata S, Oishi E, Nagata T, Tsuboi N, Oda Y, Kitazono T, Yokoo T, Ninomiya T.

J Cardiol   2021.9

β-cell function and clinical outcome in nondiabetic patients with acute ischemic stroke Reviewed International journal

2021.8

10-year trend of tooth loss and associated factors in a Japanese population-based longitudinal study. Reviewed International journal

Michiko Furuta, Kenji Takeuchi, Toru Takeshita, Yukie Shibata, Shino Suma, Shinya Kageyama, Mikari Asakawa, Jun Hata, Daigo Yoshida, Yoshihiro Shimazaki, Toshiharu Ninomiya, Yoshihisa Yamashita

BMJ open   11 ( 8 )   e048114   2021.8

Comparison of the contributions of impaired beta cell function and insulin resistance to the development of type 2 diabetes in a Japanese community: the Hisayama Study Reviewed International journal

Yoshinari M, Hirakawa Y, Hata J, Higashioka M, Honda T, Yoshida D, Mukai N, Nakamura U, Kitazono T, Ninomiya T.

Diabetologia   2021.8

Serum high-sensitivity C-reactive protein levels and the development of atrial fibrillation in a general Japanese population: the Hisayama Study Reviewed

Yoshikawa T, Hata J, Sakata S, Nagata T, Hirakawa Y, Hirooka Y, Tsutsui H, Kitazono T, Ninomiya T.

Circ J   2021.7

Development of a dementia prediction model for primary care: the Hisayama Study Reviewed International journal

Honda T, Ohara T, Yoshida D, Shibata M, Ishida Y, Furuta Y, Oishi E, Hirakawa Y, Sakata S, Hata J, Nakao T, Ninomiya T.

Alzheimers Dement (Amst)   2021.7

Current status of the certification of long-term care insurance among individuals with dementia in a Japanese community: the Hisayama Study Reviewed International journal

Ohara T, Yoshida D, Hata J, Shibata M, Honda T, Furuta Y, Hirabayashi N, Kitazono T, Nakao T, Ninomiya T.

Psychiatry Clin Neurosci   2021.5

Airflow limitation and tongue microbiota in community-dwelling elderly individuals Reviewed International journal

Takeshita T, Matsumoto K, Furuta M, Fukuyama S, Takeuchi K, Ogata H, Asakawa M, Kageyama S, Hata J, Ninomiya T, Inoue H, Yamashita Y.

ERJ Open Res   2021.5

Prevalence and mortality of sarcopenia in a community-dwelling older Japanese population: the Hisayama Study Reviewed

Nakamura K, Yoshida D, Honda T, Hata J, Shibata M, Hirakawa Y, Furuta Y, Kishimoto H, Ohara T, Kitazono T, Nakashima Y, Ninomiya T.

J Epidemiol   2021.5

Dietary fiber intake and risk of type 2 diabetes in a general Japanese population: the Hisayama Study Reviewed International journal

2021.4

Urinary N-terminal pro-B-type natriuretic peptide as a biomarker for cardiovascular events in a general Japanese population: the Hisayama Study Reviewed

Yamasaki K, Hata J, Ide T, Nagata T, Sakata S, Yoshida D, Honda T, Hirakawa Y, Nakano T, Kitazono T, Tsutsui H, Ninomiya T.

Environ Health Prev Med   2021.4

Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight Reviewed International journal

NCD Risk Factor Collaboration (NCD-RisC).

Elife   2021.3

Risk prediction for new-onset atrial fibrillation using the Minnesota code electrocardiography classification system Reviewed International journal

Igarashi Y, Nochioka K, Sakata Y, Tamai T, Ohkouchi S, Irokawa T, Ogawa H, Hayashi H, Fujihashi T, Yamanaka S, Shiroto T, Miyata S, Hata J, Yamada S, Ninomiya T, Yasuda S, Kurosawa H, Shimokawa H.

Int J Cardiol Heart Vasc   2021.3

High serum folate concentrations are associated with decreased risk of mortality among Japanese adults Reviewed International journal

Chen S, Honda T, Hata J, Sakata S, Furuta Y, Yoshida D, Shibata M, Ohara T, Hirakawa Y, Oishi E, Kitazono T, Ninomiya T.

J Nutr   2021.3

The association of small dense low-density lipoprotein cholesterol and coronary heart disease in subjects at high cardiovascular risk Reviewed

Higashioka M, Sakata S, Honda T, Hata J, Shibata M, Yoshida D, Goto K, Kitazono T, Osawa H, Ninomiya T.

J Atheroscler Thromb   2021.1

N-terminal pro-B-type natriuretic peptide and incident CKD Reviewed International journal

Sasaki T, Oishi E, Nagata T, Sakata S, Chen S, Furuta Y, Honda T, Yoshida D, Hata J, Tsuboi N, Kitazono T, Yokoo T, Ninomiya T.

Kidney Int Rep   2021.1

Serum N-terminal pro-B-type natriuretic peptide as a predictor for future development of atrial fibrillation in a general population: the Hisayama Study Reviewed International journal

Nagata T, Hata J, Sakata S, Oishi E, Honda T, Furuta Y, Ohara T, Yoshida D, Hirakawa Y, Shibata M, Ide T, Kitazono T, Tsutsui H, Ninomiya T.

Int J Cardiol   2020.12

Recent status of self-measured home blood pressure in the Japanese general population: a modern database on self-measured home blood pressure (MDAS) Reviewed

Asayama K, Tabara Y, Oishi E, Sakata S, Hisamatsu T, Godai K, Kabayama M, Tatsumi Y, Hata J, Kikuya M, Kamide K, Miura K, Ninomiya T, Ohkubo T.

Hypertens Res   2020.12

Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants Reviewed International journal

NCD Risk Factor Collaboration (NCD-RisC).

Lancet   2020.11

Association between serum glycated albumin and risk of cardiovascular disease in a Japanese community: the Hisayama Study Reviewed International journal

Mihara A, Ohara T, Hata J, Honda T, Chen S, Sakata S, Oishi E, Hirakawa Y, Nakao T, Kitazono T, Ninomiya T.

Atherosclerosis   2020.10

Study design and baseline characteristics of a population-based prospective cohort study of dementia in Japan: the Japan Prospective Studies Collaboration for Aging and Dementia (JPSC-AD) Reviewed

Ninomiya T, Nakaji S, Maeda T, Yamada M, Mimura M, Nakashima K, Mori T, Takebayashi M, Ohara T, Hata J, Kokubo Y, Uchida K, Taki Y, Kumagai S, Yonemoto K, Yoshida H, Muto K, Momozawa Y, Akiyama M, Kubo M, Ikeda M, Kanba S, Kiyohara Y; JPSC-AD Study Group.

Environ Health Prev Med   2020.10

Influence of the accumulation of unhealthy eating habits on obesity in a general Japanese population: the Hisayama Study Reviewed International journal

Ishida Y, Yoshida D, Honda T, Hirakawa Y, Shibata M, Sakata S, Furuta Y, Oishi E, Hata J, Kitazono T, Ninomiya T.

Nutrients   2020.10

Association of glucose tolerance status with pancreatic β- and α-cell mass in community-based autopsy samples of Japanese individuals: the Hisayama Study Reviewed International journal

2020.9

Five-year incidence of myopic maculopathy in a general Japanese population: the Hisayama Study Reviewed International journal

Ueda E, Yasuda M, Fujiwara K, Hashimoto S, Ohno-Matsui K, Hata J, Ishibashi T, Ninomiya T, Sonoda KH.

JAMA Ophthalmol   2020.8

Lifetime cumulative incidence of dementia in a community-dwelling elderly population in Japan Reviewed International journal

Yoshida D, Ohara T, Hata J, Shibata M, Hirakawa Y, Honda T, Furuta Y, Oishi E, Sakata S, Kanba S, Kitazono T, Ninomiya T.

Neurology   2020.8

Elevated serum glycated albumin and glycated albumin : hemoglobin A1c ratio were associated with hippocampal atrophy in a general elderly population of Japanese: the Hisayama Study Reviewed International journal

2020.7

30-minute postload plasma glucose levels during an oral glucose tolerance test predict the risk of future type 2 diabetes: the Hisayama Study Reviewed International journal

Hirakawa Y, Hata J, Yoshinari M, Higashioka M, Yoshida D, Shibata M, Honda T, Sakata S, Kato H, Teramoto T, Maki H, Nishimoto S, Kitazono T, Ninomiya T.

BMJ Open Diabetes Res Care   2020.7

Small dense low-density lipoprotein cholesterol and the risk of coronary heart disease in a Japanese community Reviewed

Higashioka M, Sakata S, Honda T, Hata J, Yoshida D, Hirakawa Y, Shibata M, Goto K, Kitazono T, Osawa H, Ninomiya T.

J Atheroscler Thromb   2020.7

Serum uric acid levels and cardiovascular mortality in a general Japanese population: the Hisayama Study Reviewed

Sakata S, Hata J, Honda T, Hirakawa Y, Oishi E, Shibata M, Yoshida D, Goto K, Kitazono T, Ninomiya T.

Hypertens Res   2020.6

Repositioning of the global epicentre of non-optimal cholesterol Reviewed International journal

NCD Risk Factor Collaboration (NCD-RisC).

Nature   2020.6

Serum homocysteine and risk of dementia in Japan Reviewed International journal

Chen S, Honda T, Ohara T, Hata J, Hirakawa Y, Yoshida D, Shibata M, Sakata S, Oishi E, Furuta Y, Kitazono T, Ninomiya T.

J Neurol Neurosurg Psychiatry   2020.5

Association of albuminuria with white matter hyperintensities volume on brain magnetic resonance imaging in elderly Japanese: the Hisayama Study Reviewed

Yamasaki K, Hata J, Furuta Y, Hirabayashi N, Ohara T, Yoshida D, Hirakawa Y, Nakano T, Kitazono T, Ninomiya T.

Circ J   2020.5

Ratios of serum eicosapentaenoic acid to arachidonic acid and docosahexaenoic acid to arachidonic acid were inversely associated with serum resistin levels: the Hisayama Study Reviewed International journal

Higashioka M, Hirakawa Y, Kawamura R, Honda T, Hata J, Yoshida D, Takata Y, Kitazono T, Osawa H, Ninomiya T.

J Diabetes Investig   2020.3

Disrupted tongue microbiota and detection of nonindigenous bacteria on the day of allogeneic hematopoietic stem cell transplantation Reviewed International journal

Oku S, Takeshita T, Futatsuki T, Kageyama S, Asakawa M, Mori Y, Miyamoto T, Hata J, Ninomiya T, Kashiwazaki H, Yamashita Y.

PLoS Pathog   2020.3

Genome-wide polygenic score and the risk of ischemic stroke in a prospective cohort: the Hisayama Study Reviewed International journal

Hachiya T, Hata J, Hirakawa Y, Yoshida D, Furuta Y, Kitazono T, Shimizu A, Ninomiya T.

Stroke   2020.3

National trends in total cholesterol obscure heterogeneous changes in HDL and non-HDL cholesterol and total-to-HDL cholesterol ratio: a pooled analysis of 458 population-based studies in Asian and Western countries Reviewed International journal

NCD Risk Factor Collaboration (NCD-RisC).

Int J Epidemiol   2020.2

Anticoagulation and risk of stroke recurrence in patients with embolic stroke of undetermined source having no potential source of embolism Reviewed International journal

Cerebrovasc Dis   2020.1

Decline in handgrip strength from midlife to late-life is associated with dementia in a Japanese community: the Hisayama Study Reviewed

Hatabe Y, Shibata M, Ohara T, Oishi E, Yoshida D, Honda T, Hata J, Kanba S, Kitazono T, Ninomiya T.

J Epidemiol   2020.1

Long-term regular exercise and intraocular pressure: the Hisayama Study Reviewed International journal

Fujiwara K, Yasuda M, Hata J, Yoshida D, Kishimoto H, Hashimoto S, Yoshitomi T, Ninomiya T, Sonoda KH.

Graefes Arch Clin Exp Ophthalmol   2019.11

Serum elaidic acid concentration and risk of dementia: the Hisayama Study Reviewed International journal

Honda T, Ohara T, Shinohara M, Hata J, Toh R, Yoshida D, Shibata M, Ishida T, Hirakawa Y, Irino Y, Sakata S, Uchida K, Kitazono T, Kanba S, Hirata KI, Ninomiya T.

Neurology   2019.11

Serum lipopolysaccharide-binding protein levels and the incidence of cardiovascular disease in a general Japanese population: the Hisayama Study Reviewed International journal

Asada M, Oishi E, Sakata S, Hata J, Yoshida D, Honda T, Furuta Y, Shibata M, Suzuki K, Watanabe H, Murayama N, Kitazono T, Yamaura K, Ninomiya T.

J Am Heart Assoc   2019.11

Association between axial length and myopic maculopathy: the Hisayama Study Reviewed International journal

Hashimoto S, Yasuda M, Fujiwara K, Ueda E, Hata J, Hirakawa Y, Ninomiya T, Sonoda KH.

Ophthalmol Retina   2019.10

Glucose tolerance levels and circumpapillary retinal nerve fiber layer thickness in a general Japanese population: the Hisayama Study Reviewed International journal

Fujiwara K, Yasuda M, Hata J, Hirakawa Y, Hashimoto S, Ueda E, Iwase A, Araie M, Yoshitomi T, Ninomiya T, Sonoda KH.

Am J Ophthalmol   2019.9

NT-proBNP and risk of dementia in a general Japanese elderly population: the Hisayama Study Reviewed International journal

Nagata T, Ohara T, Hata J, Sakata S, Furuta Y, Yoshida D, Honda T, Hirakawa Y, Ide T, Kanba S, Kitazono T, Tsutsui H, Ninomiya T.

J Am Heart Assoc   2019.9

Reduced estimated gfr and cardiac remodeling: a population-based autopsy study Reviewed International journal

Izumaru K, Hata J, Nakano T, Nakashima Y, Nagata M, Fukuhara M, Oda Y, Kitazono T, Ninomiya T.

Am J Kidney Dis   2019.9

Association between genetic risk and development of type 2 diabetes in a general Japanese population: the Hisayama Study Reviewed International journal

Inaishi J, Hirakawa Y, Horikoshi M, Akiyama M, Higashioka M, Yoshinari M, Hata J, Mukai N, Kamatani Y, Momozawa Y, Kubo M, Ninomiya T.

J Clin Endocrinol Metab   2019.8

Serum ethylamine levels as an indicator of l-theanine consumption and the risk of type 2 diabetes in a general Japanese population: the Hisayama Study Reviewed International journal

Ninomiya T, Kanzaki N, Hirakawa Y, Yoshinari M, Higashioka M, Honda T, Shibata M, Sakata S, Yoshida D, Teramoto T, Takemoto S, Nishimoto S, Hata J, Kitazono T.

Diabetes Care   2019.7

Trends in the prevalence of myopia and myopic maculopathy in a Japanese population: the Hisayama Study Reviewed International journal

Ueda E, Yasuda M, Fujiwara K, Hashimoto S, Ohno-Matsui K, Hata J, Ishibashi T, Ninomiya T, Sonoda KH.

Invest Ophthalmol Vis Sci   2019.7

Dairy consumption and risk of functional disability in an elderly Japanese population: the Hisayama Study Reviewed International journal

Yoshida D, Ohara T, Hata J, Shibata M, Hirakawa Y, Honda T, Uchida K, Takasugi S, Kitazono T, Kiyohara Y, Ninomiya T.

Am J Clin Nutr   2019.6

Objectively measured sedentary time and diabetes mellitus in a general Japanese population: the Hisayama Study Reviewed International journal

Honda T, Kishimoto H, Mukai N, Hata J, Yoshida D, Hirakawa Y, Shibata M, Ohara T, Kumagai S, Ninomiya T.

J Diabetes Investig   2019.5

Periodontitis is associated with chronic obstructive pulmonary disease Reviewed International journal

Takeuchi K, Matsumoto K, Furuta M, Fukuyama S, Takeshita T, Ogata H, Suma S, Shibata Y, Shimazaki Y, Hata J, Ninomiya T, Nakanishi Y, Inoue H, Yamashita Y.

J Dent Res   2019.5

Rising rural body-mass index is the main driver of the global obesity epidemic in adults Reviewed International journal

Nature   2019.5

Poor glycemic control and posterior circulation ischemic stroke Reviewed International journal

Kuroda J, Matsuo R, Yamaguchi Y, Sato N, Kamouchi M, Hata J, Wakisaka Y, Ago T, Kitazono T; Fukuoka Stroke Registry Investigators.

Neurol Clin Pract   2019.4

Trends in the prevalence of airflow limitation in a general Japanese population: two serial cross-sectional surveys from the Hisayama Study Reviewed International journal

Ogata H, Hirakawa Y, Matsumoto K, Hata J, Yoshida D, Fukuyama S, Inoue H, Kitazono T, Ninomiya T, Nakanishi Y.

BMJ Open   2019.3

Longitudinal changes of physical activity and sedentary time in the middle-aged and older Japanese population: the Hisayama Study Reviewed International journal

Yonemoto K, Honda T, Kishimoto H, Yoshida D, Hata J, Mukai N, Shibata M, Hirakawa Y, Ninomiya T, Kumagai S.

J Phys Act Health   2019.2

Serum magnesium and calcium levels in relation to ischemic stroke: Mendelian randomization study Reviewed International journal

Neurology   2019.2

Serum soluble triggering receptor expressed on myeloid cells 2 as a biomarker for incident dementia: the Hisayama Study Reviewed International journal

Ohara T, Hata J, Tanaka M, Honda T, Yamakage H, Yoshida D, Inoue T, Hirakawa Y, Kusakabe T, Shibata M, Teraoka T, Kitazono T, Kanba S, Satoh-Asahara N, Ninomiya T.

Ann Neurol   2019.1

Prevalence of adult epilepsy in a general Japanese population: the Hisayama Study Reviewed International journal

Tanaka A, Hata J, Akamatsu N, Mukai N, Hirakawa Y, Yoshida D, Kishimoto H, Ohara T, Mizuno T, Tsuji S, Kitazono T, Ninomiya T.

Epilepsia Open   2019.1

Moyamoya disease susceptibility variant RNF213 p.R4810K increases the risk of ischemic stroke attributable to large-artery atherosclerosis Reviewed International journal

Circulation   2019.1

A potential novel pathological implication of serum soluble triggering receptor expressed on myeloid cell 2 in insulin resistance in a general Japanese population: the Hisayama Study Reviewed International journal

Tanaka M, Honda T, Yamakage H, Hata J, Yoshida D, Hirakawa Y, Shibata M, Inoue T, Kusakabe T, Satoh-Asahara N, Ninomiya T.

Diabetes Res Clin Pract   2018.12

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes Reviewed International journal

Nat Commun   2018.12

Development and validation of modified risk prediction models for cardiovascular disease and its subtypes: the Hisayama Study Reviewed International journal

Honda T, Yoshida D, Hata J, Hirakawa Y, Ishida Y, Shibata M, Sakata S, Kitazono T, Ninomiya T.

Atherosclerosis   2018.12

Comparison of the periodontal condition in Korean and Japanese adults: a cross-sectional study Reviewed International journal

Furuta M, Takeuchi K, Shimazaki Y, Takeshita T, Shibata Y, Hata J, Yoshida D, Park DY, Ninomiya T, Yamashita Y

BMJ Open   2018.11

Trends in the prevalence of type 2 diabetes and prediabetes in a Japanese community, 1988-2012: the Hisayama Study Reviewed International journal

Mukai N, Hata J, Hirakawa Y, Ohara T, Yoshida D, Nakamura U, Kitazono T, Ninomiya T.

Diabetol Int   2018.11

Association between daily sleep duration and risk of dementia and mortality in a Japanese community Reviewed International journal

Ohara T, Honda T, Hata J, Yoshida D, Mukai N, Hirakawa Y, Shibata M, Kishimoto H, Kitazono T, Kanba S, Ninomiya T.

J Am Geriatr Soc   2018.10

Association between the ratio of serum arachidonic acid to eicosapentaenoic acid and the presence of depressive symptoms in a general Japanese population: the Hisayama Study Reviewed International journal

Shibata M, Ohara T, Yoshida D, Hata J, Mukai N, Kawano H, Kanba S, Kitazono T, Ninomiya T.

J Affect Disord   2018.9

Association of embolic sources with cause-specific functional outcomes among adults with cryptogenic stroke Reviewed International journal

Kiyuna F, Sato N, Matsuo R, Kamouchi M, Hata J, Wakisaka Y, Kuroda J, Ago T, Kitazono T; Fukuoka Stroke Registry Investigators.

JAMA Netw Open   2018.9

Periodontal status and lung function decline in the community: the Hisayama Study Reviewed International journal

Takeuchi K, Matsumoto K, Furuta M, Fukuyama S, Takeshita T, Ogata H, Suma S, Shibata Y, Shimazaki Y, Hata J, Ninomiya T, Nakanishi Y, Inoue H, Yamashita Y.

Sci Rep   2018.9

Tongue microbiota and oral health status in community-dwelling elderly adults Reviewed International journal

Asakawa M, Takeshita T, Furuta M, Kageyama S, Takeuchi K, Hata J, Ninomiya T, Yamashita Y.

mSphere   2018.8

Secular trends in the incidence, risk factors, and prognosis of transient ischemic attack in Japan: the Hisayama Study Reviewed International journal

Furuta Y, Hata J, Mukai N, Hirakawa Y, Ago T, Kitazono T, Kiyohara Y, Ninomiya T.

Atherosclerosis   2018.6

Prevalence of and risk factors for cerebral microbleeds in a general Japanese elderly community Reviewed International journal

Yubi T, Hata J, Ohara T, Mukai N, Hirakawa Y, Yoshida D, Gotoh S, Hirabayashi N, Furuta Y, Ago T, Kitazono T, Kiyohara Y, Ninomiya T.

Neurol Clin Pract   2018.6

Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: a pooled analysis of 1018 population-based measurement studies with 88.6 million participants Reviewed International journal

NCD Risk Factor Collaboration (NCD-RisC).

Int J Epidemiol   2018.6

Development and validation of a risk assessment tool for gastric cancer in a general Japanese population Reviewed International journal

Iida M, Ikeda F, Hata J, Hirakawa Y, Ohara T, Mukai N, Yoshida D, Yonemoto K, Esaki M, Kitazono T, Kiyohara Y, Ninomiya T.

Gastric Cancer   2018.5

Patterns and levels of sedentary behavior and physical activity in a general Japanese population: the Hisayama Study Reviewed

Chen T, Kishimoto H, Honda T, Hata J, Yoshida D, Mukai N, Shibata M, Ninomiya T, Kumagai S.

J Epidemiol   2018.5

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes Reviewed International journal

Nat Genet   2018.4

Insulin resistance and clinical outcomes after acute ischemic stroke Reviewed International journal

Ago T, Matsuo R, Hata J, Wakisaka Y, Kuroda J, Kitazono T, Kamouchi M; Fukuoka Stroke Registry Investigators.

Neurology   2018.4

Clustering of risk factors and the risk of incident cardiovascular disease in asian and caucasian populations: results from the Asia Pacific Cohort Studies Collaboration Reviewed International journal

Peters SAE, Wang X, Lam TH, Kim HC, Ho S, Ninomiya T, Knuiman M, Vaartjes I, Bots ML, Woodward M; Asia Pacific Cohort Studies Collaboration.

BMJ Open   2018.3

Prevalence and risk factors for polypoidal choroidal vasculopathy in a general Japanese population: the Hisayama Study Reviewed International journal

Fujiwara K, Yasuda M, Hata J, Oshima Y, Hashimoto S, Yoshitomi T, Kiyohara Y, Ishibashi T, Ninomiya T, Sonoda KH.

Semin Ophthalmol   2018.1

Albuminuria increases the risks for both Alzheimer disease and vascular dementia in community-dwelling Japanese elderly: the Hisayama Study Reviewed International journal

Takae K, Hata J, Ohara T, Yoshida D, Shibata M, Mukai N, Hirakawa Y, Kishimoto H, Tsuruya K, Kitazono T, Kiyohara Y, Ninomiya T.

J Am Heart Assoc   2018.1

The ratio of serum eicosapentaenoic acid to arachidonic acid and risk of cancer death in a Japanese community: the Hisayama Study Reviewed

2017.12

Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128.9 million children, adolescents, and adults Reviewed International journal

NCD Risk Factor Collaboration (NCD-RisC).

Lancet   2017.12

Association between onset-to-door time and clinical outcomes after ischemic stroke Reviewed International journal

Matsuo R, Yamaguchi Y, Matsushita T, Hata J, Kiyuna F, Fukuda K, Wakisaka Y, Kuroda J, Ago T, Kitazono T, Kamouchi M; Fukuoka Stroke Registry Investigators.

Stroke   2017.11

Association of airflow limitation with carotid atherosclerosis in a Japanese community: the Hisayama Study Reviewed

Kudo K, Hata J, Matsumoto K, Shundo Y, Fukuyama S, Inoue H, Kitazono T, Kiyohara Y, Ninomiya T, Nakanishi Y.

Circ J   2017.11

Morning and evening blood pressures are associated with intima-media thickness in a general population: the Hisayama Study Reviewed

Sakata S, Hata J, Fukuhara M, Yonemoto K, Mukai N, Yoshida D, Kishimoto H, Ohtsubo T, Kitazono T, Kiyohara Y, Ninomiya T.

Circ J   2017.10

Alternative measures of hyperglycemia and risk of Alzheimer's disease in the community: the Hisayama Study Reviewed International journal

Mukai N, Ohara T, Hata J, Hirakawa Y, Yoshida D, Kishimoto H, Koga M, Nakamura U, Kitazono T, Kiyohara Y, Ninomiya T.

J Clin Endocrinol Metab   2017.8

Association between serum vitamin D and all-cause and cause-specific death in a general Japanese population: the Hisayama Study Reviewed

Umehara K, Mukai N, Hata J, Hirakawa Y, Ohara T, Yoshida D, Kishimoto H, Kitazono T, Hoka S, Kiyohara Y, Ninomiya T.

Circ J   2017.8

Left atrial size and long-term risk of recurrent stroke after acute ischemic stroke in patients with nonvalvular atrial fibrillation Reviewed International journal

Ogata T, Matsuo R, Kiyuna F, Hata J, Ago T, Tsuboi Y, Kitazono T, Kamouchi M; FSR Investigators.

J Am Heart Assoc   2017.8

Day-to-day blood pressure variability and risk of dementia in a general Japanese elderly population: the Hisayama Study Reviewed International journal

Oishi E, Ohara T, Sakata S, Fukuhara M, Hata J, Yoshida D, Shibata M, Ohtsubo T, Kitazono T, Kiyohara Y, Ninomiya T.

Circulation   2017.8

Prognostic value of variability in systolic blood pressure related to vascular events and premature death in type 2 diabetes mellitus: the ADVANCE-ON Study Reviewed International journal

Ohkuma T, Woodward M, Jun M, Muntner P, Hata J, Colagiuri S, Harrap S, Mancia G, Poulter N, Williams B, Rothwell P, Chalmers J; ADVANCE Collaborative Group.

Hypertension   2017.8

Serum non-high-density lipoprotein cholesterol and risk of cardiovascular disease in community dwellers with chronic kidney disease: the Hisayama Study Reviewed

Usui T, Nagata M, Hata J, Mukai N, Hirakawa Y, Yoshida D, Kishimoto H, Kitazono T, Kiyohara Y, Ninomiya T.

J Atheroscler Thromb   2017.7

Dietary protein intake and stroke risk in a general Japanese population: the Hisayama Study Reviewed International journal

Ozawa M, Yoshida D, Hata J, Ohara T, Mukai N, Shibata M, Uchida K, Nagata M, Kitazono T, Kiyohara Y, Ninomiya T.

Stroke   2017.6

Tooth loss and risk of dementia in the community: the Hisayama Study Reviewed International journal

Takeuchi K, Ohara T, Furuta M, Takeshita T, Shibata Y, Hata J, Yoshida D, Yamashita Y, Ninomiya T.

J Am Geriatr Soc   2017.5

Trends in dementia prevalence, incidence, and survival rate in a Japanese community Reviewed International journal

Ohara T, Hata J, Yoshida D, Mukai N, Nagata M, Iwaki T, Kitazono T, Kanba S, Kiyohara Y, Ninomiya T.

Neurology   2017.5

Intracerebral hemorrhage location and outcome among INTERACT2 participants Reviewed International journal

Delcourt C, Sato S, Zhang S, Sandset EC, Zheng D, Chen X, Hackett ML, Arima H, Hata J, Heeley E, Al-Shahi Salman R, Robinson T, Davies L, Lavados PM, Lindley RI, Stapf C, Chalmers J, Anderson CS; INTERACT2 Investigators.

Neurology   2017.4

Genetic predisposition to ischemic stroke: a polygenic risk score Reviewed International journal

Hachiya T, Kamatani Y, Takahashi A, Hata J, Furukawa R, Shiwa Y, Yamaji T, Hara M, Tanno K, Ohmomo H, Ono K, Takashima N, Matsuda K, Wakai K, Sawada N, Iwasaki M, Yamagishi K, Ago T, Ninomiya T, Fukushima A, Hozawa A, Minegishi N, Satoh M, Endo R, Sasaki M, Sakata K, Kobayashi S, Ogasawara K, Nakamura M, Hitomi J, Kita Y, Tanaka K, Iso H, Kitazono T, Kubo M, Tanaka H, Tsugane S, Kiyohara Y, Yamamoto M, Sobue K, Shimizu A.

Stroke   2017.2

Adverse influence of pre-stroke dementia on short-term functional outcomes in patients with acute ischemic stroke: the Fukuoka Stroke Registry Reviewed International journal

Wakisaka Y, Matsuo R, Hata J, Kuroda J, Kitazono T, Kamouchi M, Ago T; Fukuoka Stroke Registry Investigators.

Cerebrovasc Dis   2017.1

Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19.1 million participants Reviewed International journal

NCD Risk Factor Collaboration (NCD-RisC).

Lancet   2017.1

Associations with health-related quality of life after intracerebral haemorrhage: pooled analysis of INTERACT studies Reviewed International journal

Delcourt C, Zheng D, Chen X, Hackett M, Arima H, Hata J, Heeley E, Al-Shahi Salman R, Woodward M, Huang Y, Robinson T, Lavados PM, Lindley RI, Stapf C, Davies L, Chalmers J, Anderson CS, Sato S; INTERACT Investigators.

J Neurol Neurosurg Psychiatry   2017.1

Combination of helicobacter pylori antibody and serum pepsinogen as a good predictive tool of gastric cancer incidence: 20-year prospective data from the Hisayama Study Reviewed

Ikeda F, Shikata K, Hata J, Fukuhara M, Hirakawa Y, Ohara T, Mukai N, Nagata M, Yoshida D, Yonemoto K, Esaki M, Kitazono T, Kiyohara Y, Ninomiya T.

J Epidemiol   2016.12

The development of a risk score for incident atrial fibrillation in Japanese general population cohorts: a collaborative meta-analysis Reviewed International journal

Kokubo Yoshihiro, Imano Hironori, Hata Jun, Murakoshi Nobuyuki, Aizawa Yoshifusa, Iso Hiroyasu, Ninomiya Toshiharu, Nakamura Fumiaki, Miyamoto Yoshihiro, Okamura Tomonori, Tomita Hirofumi, Okumura Ken

CIRCULATION   134   2016.11

PKCη deficiency improves lipid metabolism and atherosclerosis in apolipoprotein E-deficient mice Reviewed International journal

2016.10

Association between diabetes and hippocampal atrophy in elderly Japanese: the Hisayama Study Reviewed International journal

Hirabayashi N, Hata J, Ohara T, Mukai N, Nagata M, Shibata M, Gotoh S, Furuta Y, Yamashita F, Yoshihara K, Kitazono T, Sudo N, Kiyohara Y, Ninomiya T.

Diabetes Care   2016.9

Prognostic significance of hyponatremia in acute intracerebral hemorrhage: pooled analysis of the Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial Studies Reviewed International journal

Carcel C, Sato S, Zheng D, Heeley E, Arima H, Yang J, Wu G, Chen G, Zhang S, Delcourt C, Lavados P, Robinson T, Lindley RI, Wang X, Chalmers J, Anderson CS; Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial 2 Investigators.

Crit Care Med   2016.7

A century of trends in adult human height Reviewed International journal

NCD Risk Factor Collaboration (NCD-RisC).

Elife   2016.7

Serum uric acid as a risk factor for chronic kidney disease in a Japanese community: the Hisayama Study Reviewed

Takae K, Nagata M, Hata J, Mukai N, Hirakawa Y, Yoshida D, Kishimoto H, Tsuruya K, Kitazono T, Kiyohara Y, Ninomiya T.

Circ J   2016.7

Estimated GFR and the effect of intensive blood pressure lowering after acute intracerebral hemorrhage Reviewed International journal

Zheng D, Sato S, Arima H, Heeley E, Delcourt C, Cao Y, Chalmers J, Anderson CS; INTERACT2 Investigators.

Am J Kidney Dis   2016.7

Foveal and macular thickness in a Japanese population: the Hisayama Study Reviewed International journal

Hashimoto S, Yasuda M, Ninomiya T, Hata J, Yoshida D, Tahara-Asakuma T, Hirakawa Y, Arakawa S, Fujiwara K, Kiyohara Y, Ishibashi T.

Ophthalmic Epidemiol   2016.6

Plasma C-reactive protein and clinical outcomes after acute ischemic stroke: a prospective observational study Reviewed International journal

Matsuo R, Ago T, Hata J, Wakisaka Y, Kuroda J, Kuwashiro T, Kitazono T, Kamouchi M; Fukuoka Stroke Registry Investigators.

PLoS One   2016.6

Elevated 2-hour post-load glucose levels and longer duration of diabetes are risk factors for hippocampal atrophy in elderly Japanese: the Hisayama Study Reviewed International journal

Naoki Hirabayashi, Jun Hata, Tomoyuki Ohara, Naoko Mukai, Masaharu Nagata, Mao Shibata, Seiji Goto, Yoshihiko Furuta, Fumio Yamashita, Kazufumi Yoshihara, Takanari Kitazono, Nobuyuki Sudo, Yutaka Kiyohara, Toshiharu Ninomiya

DIABETES   65   A361 - A361   2016.6

Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4.4 million participants Reviewed International journal

NCD Risk Factor Collaboration (NCD-RisC).

Lancet   2016.4

The long-term association between physical activity and risk of dementia in the community: the Hisayama Study Reviewed International journal

Kishimoto H, Ohara T, Hata J, Ninomiya T, Yoshida D, Mukai N, Nagata M, Ikeda F, Fukuhara M, Kumagai S, Kanba S, Kitazono T, Kiyohara Y.

Eur J Epidemiol   2016.3

Low ambient temperature and intracerebral hemorrhage: the INTERACT2 study Reviewed International journal

Zheng D, Arima H, Sato S, Gasparrini A, Heeley E, Delcourt C, Lo S, Huang Y, Wang J, Stapf C, Robinson T, Lavados P, Chalmers J, Anderson CS; INTERACT2 Investigators.

PLoS One   2016.2

Determinants and prognostic significance of hematoma sedimentation levels in acute intracerebral hemorrhage Reviewed International journal

Sato S, Delcourt C, Zhang S, Arima H, Heeley E, Zheng D, Al-Shahi Salman R, Stapf C, Tzourio C, Robinson T, Lindley RI, Chalmers J, Anderson CS; INTERACT2 Investigators.

Cerebrovasc Dis   2016.1

Adjustment of cell-type composition minimizes systematic bias in blood dna methylation profiles derived by DNA collection protocols Reviewed International journal

Shiwa Y, Hachiya T, Furukawa R, Ohmomo H, Ono K, Kudo H, Hata J, Hozawa A, Iwasaki M, Matsuda K, Minegishi N, Satoh M, Tanno K, Yamaji T, Wakai K, Hitomi J, Kiyohara Y, Kubo M, Tanaka H, Tsugane S, Yamamoto M, Sobue K, Shimizu A.

PLoS One   2016.1

Influence of statin pretreatment on initial neurological severity and short-term functional outcome in acute ischemic stroke patients: the Fukuoka Stroke Registry Reviewed International journal

Ishikawa H, Wakisaka Y, Matsuo R, Makihara N, Hata J, Kuroda J, Ago T, Kitayama J, Nakane H, Kamouchi M, Kitazono T; Fukuoka Stroke Registry Investigators.

Cerebrovasc Dis   2016.1

Causes of ischemic stroke in patients with non-valvular atrial fibrillation Reviewed International journal

Nakamura A, Kuroda J, Ago T, Hata J, Matsuo R, Arakawa S, Kuwashiro T, Yasaka M, Okada Y, Kitazono T, Kamouchi M; Fukuoka Stroke Registry Investigators.

Cerebrovasc Dis   2016.1

Insulin resistance is a risk factor for increased intraocular pressure: the Hisayama Study Reviewed International journal

Fujiwara K, Yasuda M, Ninomiya T, Hata J, Hashimoto S, Yoshitomi T, Kiyohara Y, Ishibashi T.

Invest Ophthalmol Vis Sci   2015.12

Higher mortality in patients with right hemispheric intracerebral haemorrhage: INTERACT1 and 2 Reviewed International journal

Sato S, Heeley E, Arima H, Delcourt C, Hirakawa Y, Pamidimukkala V, Li Z, Tao Q, Xu Y, Hennerici MG, Robinson T, Tzourio C, Lindley RI, Chalmers J, Anderson CS; INTERACT Investigators, Anderson CS, Huang Y, Wang JG, Arima H, Neal B, Peng B, Heeley E, Skulina C, Parsons MW, Kim JS, Tao QL, Li YC, Jiang JD, Tai LW, Zhang LJ, Xu E, Cheng Y, Heritier S, Morgenstern LB, Chalmers J.

J Neurol Neurosurg Psychiatry   2015.12

Midlife and late-life smoking and risk of dementia in the community: the Hisayama Study Reviewed International journal

Ohara T, Ninomiya T, Hata J, Ozawa M, Yoshida D, Mukai N, Nagata M, Iwaki T, Kitazono T, Kanba S, Kiyohara Y.

J Am Geriatr Soc   2015.11

Hematocrit and the risk of cardiovascular disease in a Japanese community: the Hisayama Study Reviewed International journal

Gotoh S, Hata J, Ninomiya T, Hirakawa Y, Nagata M, Mukai N, Fukuhara M, Ikeda F, Ago T, Kitazono T, Kiyohara Y.

Atherosclerosis   2015.9

Day-by-day blood pressure variability and functional outcome after acute ischemic stroke: Fukuoka Stroke Registry Reviewed International journal

Fukuda K, Kai H, Kamouchi M, Hata J, Ago T, Nakane H, Imaizumi T, Kitazono T; FSR Investigators.

Stroke   2015.7

Covariate-adjusted measures of discrimination for survival data Reviewed International journal

White IR, Rapsomaniki E; Emerging Risk Factors Collaboration.

Biom J   2015.7

Association of hemoglobin A1c and glycated albumin with carotid atherosclerosis in community-dwelling Japanese subjects: the Hisayama Study Reviewed International journal

Mukai N, Ninomiya T, Hata J, Hirakawa Y, Ikeda F, Fukuhara M, Hotta T, Koga M, Nakamura U, Kang D, Kitazono T, Kiyohara Y.

Cardiovasc Diabetol   2015.6

Sex differences in short-term outcomes after acute ischemic stroke: the Fukuoka Stroke Registry Reviewed International journal

Irie F, Kamouchi M, Hata J, Matsuo R, Wakisaka Y, Kuroda J, Ago T, Kitazono T; FSR Investigators.

Stroke   2015.2

Optimal achieved blood pressure in acute intracerebral hemorrhage: INTERACT2 Reviewed International journal

Arima H, Heeley E, Delcourt C, Hirakawa Y, Wang X, Woodward M, Robinson T, Stapf C, Parsons M, Lavados PM, Huang Y, Wang J, Chalmers J, Anderson CS; INTERACT2 Investigators.

Neurology   2015.2

Angiotensin I-converting enzyme gene polymorphism enhances the effect of hypercholesterolemia on the risk of coronary heart disease in a general Japanese population: the Hisayama Study Reviewed

Kondo H, Ninomiya T, Hata J, Hirakawa Y, Yonemoto K, Arima H, Nagata M, Tsuruya K, Kitazono T, Kiyohara Y.

J Atheroscler Thromb   2015.1

Effects of hydrochlorothiazide on oxidative stress and pulse pressure in hypertensive patients with chronic stroke: the EMINENT Study Reviewed

Nakane H, Kamouchi M, Hata J, Ibayashi S, Kusuda K, Omae T, Nagao T, Ago T, Kitazono T; EMINENT Study Investigators.

Intern Med   2015.1

Off-hour admission and outcomes in patients with acute intracerebral hemorrhage in the INTERACT2 trial Reviewed International journal

Sato S, Arima H, Heeley E, Hirakawa Y, Delcourt C, Lindley RI, Robinson T, Huang Y, Morgenstern L, Stapf C, Wang J, Chalmers J, Anderson CS; INTERACT2 Investigators.

Cerebrovasc Dis   2015.1

Thrombolytic therapy with intravenous recombinant tissue plasminogen activator in Japanese older patients with acute ischemic stroke: Fukuoka Stroke Registry Reviewed International journal

Matsuo R, Kamouchi M, Ago T, Hata J, Shono Y, Kuroda J, Wakisaka Y, Sugimori H, Kitazono T; FSR investigators.

Geriatr Gerontol Int   2014.10

Intravenous thrombolysis with recombinant tissue plasminogen activator for ischemic stroke patients over 80 years old: the Fukuoka Stroke Registry Reviewed International journal

Matsuo R, Kamouchi M, Fukuda H, Hata J, Wakisaka Y, Kuroda J, Ago T, Kitazono T; FSR Investigators.

PLoS One   2014.10

Significance of plasma adiponectin for diagnosis, neurological severity and functional outcome in ischemic stroke: Research for Biomarkers in Ischemic Stroke (REBIOS) Reviewed International journal

Kuwashiro T, Ago T, Kamouchi M, Matsuo R, Hata J, Kuroda J, Fukuda K, Sugimori H, Fukuhara M, Awano H, Isomura T, Suzuki K, Yasaka M, Okada Y, Kiyohara Y, Kitazono T.

Metabolism   2014.9

Cardiovascular disease, chronic kidney disease, and diabetes mortality burden of cardiometabolic risk factors from 1980 to 2010: a comparative risk assessment Reviewed International journal

Global Burden of Metabolic Risk Factors for Chronic Diseases Collaboration.

Lancet Diabetes Endocrinol   2014.8

Impact of the 1425G/A polymorphism of PRKCH on the recurrence of ischemic stroke: Fukuoka Stroke Registry Reviewed International journal

Matsuo R, Ago T, Hata J, Kuroda J, Wakisaka Y, Sugimori H, Kitazono T, Kamouchi M; FSR Investigators.

J Stroke Cerebrovasc Dis   2014.7

Gastrointestinal bleeding in acute ischemic stroke: recent trends from the Fukuoka Stroke Registry Reviewed International journal

Ogata T, Kamouchi M, Matsuo R, Hata J, Kuroda J, Ago T, Sugimori H, Inoue T, Kitazono T; Fukuoka Stroke Registry.

Cerebrovasc Dis Extra   2014.7

Midlife and late-life handgrip strength and risk of cause-specific death in a general Japanese population: the Hisayama Study Reviewed International journal

Kishimoto H, Hata J, Ninomiya T, Nemeth H, Hirakawa Y, Yoshida D, Kumagai S, Kitazono T, Kiyohara Y.

J Epidemiol Community Health   2014.7

Milk and dairy consumption and risk of dementia in an elderly Japanese population: the Hisayama Study Reviewed International journal

Ozawa M, Ohara T, Ninomiya T, Hata J, Yoshida D, Mukai N, Nagata M, Uchida K, Shirota T, Kitazono T, Kiyohara Y.

J Am Geriatr Soc   2014.7

Plasma S100A12 is associated with functional outcome after ischemic stroke: Research for Biomarkers in Ischemic Stroke Reviewed International journal

Wakisaka Y, Ago T, Kamouchi M, Kuroda J, Matsuo R, Hata J, Gotoh S, Isomura T, Awano H, Suzuki K, Fukuda K, Okada Y, Kiyohara Y, Ooboshi H, Kitazono T; REBIOS Investigators.

J Neurol Sci   2014.5

Non-high-density lipoprotein cholesterol and the development of coronary heart disease and stroke subtypes in a general Japanese population: the Hisayama Study Reviewed International journal

Imamura T, Doi Y, Ninomiya T, Hata J, Nagata M, Ikeda F, Mukai N, Hirakawa Y, Yoshida D, Fukuhara M, Kitazono T, Kiyohara Y.

Atherosclerosis   2014.4

Metabolic mediators of the effects of body-mass index, overweight, and obesity on coronary heart disease and stroke: a pooled analysis of 97 prospective cohorts with 1.8 million participants Reviewed International journal

Global Burden of Metabolic Risk Factors for Chronic Diseases Collaboration (BMI Mediated Effects), Lu Y, Hajifathalian K, Ezzati M, Woodward M, Rimm EB, Danaei G.

Lancet   2014.3

Glycated hemoglobin measurement and prediction of cardiovascular disease Reviewed International journal

JAMA   2014.3

Trends in the prevalence of type 2 diabetes and prediabetes in community-dwelling Japanese subjects: the Hisayama Study Reviewed International journal

Mukai N, Doi Y, Ninomiya T, Hirakawa Y, Nagata M, Yoshida D, Hata J, Fukuhara M, Nakamura U, Kitazono T, Kiyohara Y.

J Diabetes Investig   2014.3

ABCD3 and ABCD3-I scores are superior to ABCD2 score in the prediction of short- and long-term risks of stroke after transient ischemic attack Reviewed International journal

Kiyohara T, Kamouchi M, Kumai Y, Ninomiya T, Hata J, Yoshimura S, Ago T, Okada Y, Kitazono T; Fukuoka Stroke Registry Investigators.

Stroke   2014.2

Thresholds of various glycemic measures for diagnosing diabetes based on prevalence of retinopathy in community-dwelling Japanese subjects: the Hisayama Study Reviewed International journal

Mukai N, Yasuda M, Ninomiya T, Hata J, Hirakawa Y, Ikeda F, Fukuhara M, Hotta T, Koga M, Nakamura U, Kang D, Kitazono T, Kiyohara Y.

Cardiovasc Diabetol   2014.2

A low ankle brachial index is associated with an increased risk of cardiovascular disease: the Hisayama Study Reviewed

Kojima I, Ninomiya T, Hata J, Fukuhara M, Hirakawa Y, Mukai N, Yoshida D, Kitazono T, Kiyohara Y.

J Atheroscler Thromb   2014.1

Trends in the incidence and survival of intracerebral hemorrhage by its location in a Japanese community Reviewed

Gotoh S, Hata J, Ninomiya T, Hirakawa Y, Nagata M, Mukai N, Fukuhara M, Ikeda F, Shikata K, Kamouchi M, Kitazono T, Kiyohara Y.

Circ J   2014.1

High blood pressure after acute ischemic stroke is associated with poor clinical outcomes: Fukuoka Stroke Registry Reviewed International journal

Ishitsuka K, Kamouchi M, Hata J, Fukuda K, Matsuo R, Kuroda J, Ago T, Kuwashiro T, Sugimori H, Nakane H, Kitazono T; FSR Investigators.

Hypertension   2014.1

Statins and the risks of stroke recurrence and death after ischemic stroke: the Fukuoka Stroke Registry Reviewed International journal

Makihara N, Kamouchi M, Hata J, Matsuo R, Ago T, Kuroda J, Kuwashiro T, Sugimori H, Kitazono T; Fukuoka Stroke Registry Investigators.

Atherosclerosis   2013.12

Magnesium intake decreases type 2 diabetes risk through the improvement of insulin resistance and inflammation: the Hisayama Study Reviewed International journal

Hata A, Doi Y, Ninomiya T, Mukai N, Hirakawa Y, Hata J, Ozawa M, Uchida K, Shirota T, Kitazono T, Kiyohara Y.

Diabet Med   2013.12

Association between ratio of serum eicosapentaenoic acid to arachidonic acid and risk of cardiovascular disease: the Hisayama Study Reviewed International journal

Ninomiya T, Nagata M, Hata J, Hirakawa Y, Ozawa M, Yoshida D, Ohara T, Kishimoto H, Mukai N, Fukuhara M, Kitazono T, Kiyohara Y.

Atherosclerosis   2013.12

Intensity of anticoagulation and clinical outcomes in acute cardioembolic stroke: the Fukuoka Stroke Registry Reviewed International journal

Nakamura A, Ago T, Kamouchi M, Hata J, Matsuo R, Kuroda J, Kuwashiro T, Sugimori H, Kitazono T; Fukuoka Stroke Registry Investigators.

Stroke   2013.11

Haemoglobin A1c even within non-diabetic level is a predictor of cardiovascular disease in a general Japanese population: the Hisayama Study Reviewed International journal

Ikeda F, Doi Y, Ninomiya T, Hirakawa Y, Mukai N, Hata J, Shikata K, Yoshida D, Matsumoto T, Kitazono T, Kiyohara Y.

Cardiovasc Diabetol   2013.11

Elevated depressive symptoms in metabolic syndrome in a general population of Japanese men: a cross-sectional study Reviewed International journal

Sekita A, Arima H, Ninomiya T, Ohara T, Doi Y, Hirakawa Y, Fukuhara M, Hata J, Yonemoto K, Ga Y, Kitazono T, Kanba S, Kiyohara Y.

BMC Public Health   2013.9

Temporal trends in sudden unexpected death in a general population: the Hisayama Study Reviewed International journal

Nagata M, Ninomiya T, Doi Y, Hata J, Ikeda F, Mukai N, Tsuruya K, Oda Y, Kitazono T, Kiyohara Y.

Am Heart J   2013.6

Rapid blood-pressure lowering in patients with acute intracerebral hemorrhage Reviewed International journal

Anderson CS, Heeley E, Huang Y, Wang J, Stapf C, Delcourt C, Lindley R, Robinson T, Lavados P, Neal B, Hata J, Arima H, Parsons M, Li Y, Wang J, Heritier S, Li Q, Woodward M, Simes RJ, Davis SM, Chalmers J; INTERACT2 Investigators.

N Engl J Med   2013.6

White-coat and masked hypertension are associated with carotid atherosclerosis in a general population: the Hisayama Study Reviewed International journal

Fukuhara M, Arima H, Ninomiya T, Hata J, Hirakawa Y, Doi Y, Yonemoto K, Mukai N, Nagata M, Ikeda F, Matsumura K, Kitazono T, Kiyohara Y.

Stroke   2013.6

Clinical significance of plasma vegf value in ischemic stroke: Research for Biomarkers in Ischemic Stroke (REBIOS) Study Reviewed International journal

Matsuo R, Ago T, Kamouchi M, Kuroda J, Kuwashiro T, Hata J, Sugimori H, Fukuda K, Gotoh S, Makihara N, Fukuhara M, Awano H, Isomura T, Suzuki K, Yasaka M, Okada Y, Kiyohara Y, Kitazono T.

BMC Neurol   2013.4

The global cardiovascular risk transition: associations of four metabolic risk factors with national income, urbanization, and western diet in 1980 and 2008 Reviewed International journal

Danaei G, Singh GM, Paciorek CJ, Lin JK, Cowan MJ, Finucane MM, Farzadfar F, Stevens GA, Riley LM, Lu Y, Rao M, Ezzati M; Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group.

Circulation   2013.4

Brachial-ankle pulse wave velocity predicts the development of cardiovascular disease in a general Japanese population: the Hisayama Study Reviewed International journal

Ninomiya T, Kojima I, Doi Y, Fukuhara M, Hirakawa Y, Hata J, Kitazono T, Kiyohara Y.

J Hypertens   2013.3

Angiopoietin-like protein 2 is associated with chronic kidney disease in a general Japanese population: the Hisayama Study Reviewed

Usui T, Ninomiya T, Nagata M, Takahashi O, Doi Y, Hata J, Fukuhara M, Kitazono T, Oike Y, Kiyohara Y.

Circ J   2013.1

Angiopoietin-like protein 2 and risk of type 2 diabetes in a general Japanese population: the Hisayama Study Reviewed International journal

Doi Y, Ninomiya T, Hirakawa Y, Takahashi O, Mukai N, Hata J, Iwase M, Kitazono T, Oike Y, Kiyohara Y.

Diabetes Care   2013.1

Prediction of kidney-related outcomes in patients with type 2 diabetes Reviewed International journal

Jardine MJ, Hata J, Woodward M, Perkovic V, Ninomiya T, Arima H, Zoungas S, Cass A, Patel A, Marre M, Mancia G, Mogensen CE, Poulter N, Chalmers J; ADVANCE Collaborative Group.

Am J Kidney Dis   2012.11

Association between glucose tolerance level and cancer death in a general Japanese population: the Hisayama Study Reviewed International journal

Hirakawa Y, Ninomiya T, Mukai N, Doi Y, Hata J, Fukuhara M, Iwase M, Kitazono T, Kiyohara Y.

Am J Epidemiol   2012.11

Resting heart rate and the risk of microvascular complications in patients with type 2 diabetes mellitus Reviewed International journal

Hillis GS, Hata J, Woodward M, Perkovic V, Arima H, Chow CK, Zoungas S, Patel A, Poulter NR, Mancia G, Williams B, Chalmers J.

J Am Heart Assoc   2012.10

Self-reported dietary intake of potassium, calcium, and magnesium and risk of dementia in the Japanese: the Hisayama Study Reviewed International journal

Ozawa M, Ninomiya T, Ohara T, Hirakawa Y, Doi Y, Hata J, Uchida K, Shirota T, Kitazono T, Kiyohara Y.

J Am Geriatr Soc   2012.8

Smoking cessation improves mortality in Japanese men: the Hisayama Study Reviewed International journal

Ikeda F, Ninomiya T, Doi Y, Hata J, Fukuhara M, Matsumoto T, Kiyohara Y.

Tob Control   2012.7

Proteinuria and clinical outcomes after ischemic stroke Reviewed International journal

Kumai Y, Kamouchi M, Hata J, Ago T, Kitayama J, Nakane H, Sugimori H, Kitazono T; FSR Investigators.

Neurology   2012.6

Optimal cutoff value of the serum pepsinogen level for prediction of gastric cancer incidence: the Hisayama Study Reviewed International journal

Shikata K, Ninomiya T, Yonemoto K, Ikeda F, Hata J, Doi Y, Fukuhara M, Matsumoto T, Iida M, Kitazono T, Kiyohara Y.

Scand J Gastroenterol   2012.6

Impact of lower range of prehypertension on cardiovascular events in a general population: the Hisayama Study Reviewed International journal

Fukuhara M, Arima H, Ninomiya T, Hata J, Yonemoto K, Doi Y, Hirakawa Y, Matsumura K, Kitazono T, Kiyohara Y.

J Hypertens   2012.5

Dietary vitamin a intake and incidence of gastric cancer in a general Japanese population: the Hisayama Study Reviewed International journal

Miyazaki M, Doi Y, Ikeda F, Ninomiya T, Hata J, Uchida K, Shirota T, Matsumoto T, Iida M, Kiyohara Y.

Gastric Cancer   2012.4

White blood cell count and risk of gastric cancer incidence in a general Japanese population: the Hisayama Study Reviewed International journal

Iida M, Ikeda F, Ninomiya T, Yonemoto K, Doi Y, Hata J, Matsumoto T, Iida M, Kiyohara Y.

Am J Epidemiol   2012.3

The factors associated with a functional outcome after ischemic stroke in diabetic patients: the Fukuoka Stroke Registry Reviewed International journal

Kuwashiro T, Kamouchi M, Ago T, Hata J, Sugimori H, Kitazono T.

J Neurol Sci   2012.2

Cut-off values of fasting and post-load plasma glucose and HbA1c for predicting type 2 diabetes in community-dwelling Japanese subjects: the Hisayama Study Reviewed International journal

Mukai N, Doi Y, Ninomiya T, Hata J, Hirakawa Y, Fukuhara M, Iwase M, Kiyohara Y.

Diabet Med   2012.1

Two risk score models for predicting incident type 2 diabetes in Japan Reviewed International journal

Doi Y, Ninomiya T, Hata J, Hirakawa Y, Mukai N, Iwase M, Kiyohara Y.

Diabet Med   2012.1

Prevalence and causes of functional disability in an elderly general population of Japanese: the Hisayama Study Reviewed

Yoshida D, Ninomiya T, Doi Y, Hata J, Fukuhara M, Ikeda F, Mukai N, Kiyohara Y.

J Epidemiol   2012.1

Insulin resistance and the development of cardiovascular disease in a Japanese community: the Hisayama Study Reviewed

Gotoh S, Doi Y, Hata J, Ninomiya T, Mukai N, Fukuhara M, Kamouchi M, Kitazono T, Kiyohara Y.

J Atheroscler Thromb   2012.1

N-terminal pro-brain natriuretic peptide and risk of cardiovascular events in a Japanese community: the Hisayama Study Reviewed International journal

Doi Y, Ninomiya T, Hata J, Hirakawa Y, Mukai N, Ikeda F, Fukuhara M, Iwase M, Kiyohara Y.

Arterioscler Thromb Vasc Biol   2011.12

Prestroke glycemic control is associated with the functional outcome in acute ischemic stroke: the Fukuoka Stroke Registry Reviewed International journal

Kamouchi M, Matsuki T, Hata J, Kuwashiro T, Ago T, Sambongi Y, Fukushima Y, Sugimori H, Kitazono T; FSR Investigators.

Stroke   2011.10

Glucose tolerance status and risk of dementia in the community: the Hisayama Study Reviewed International journal

Ohara T, Doi Y, Ninomiya T, Hirakawa Y, Hata J, Iwaki T, Kanba S, Kiyohara Y.

Neurology   2011.9

Association of Alzheimer disease pathology with abnormal lipid metabolism: the Hisayama Study Reviewed International journal

Matsuzaki T, Sasaki K, Hata J, Hirakawa Y, Fujimi K, Ninomiya T, Suzuki SO, Kanba S, Kiyohara Y, Iwaki T.

Neurology   2011.9

Effects of blood pressure lowering on major vascular events among patients with isolated diastolic hypertension: the Perindopril Protection Against Recurrent Stroke Study (PROGRESS) trial Reviewed International journal

Arima H, Anderson C, Omae T, Woodward M, Hata J, Murakami Y, Macmahon S, Neal B, Chalmers J; PROGRESS Collaborative Group.

Stroke   2011.8

Midlife and late-life blood pressure and dementia in Japanese elderly: the Hisayama Study Reviewed International journal

Ninomiya T, Ohara T, Hirakawa Y, Yoshida D, Doi Y, Hata J, Kanba S, Iwaki T, Kiyohara Y.

Hypertension   2011.7

Apolipoprotein genotype for prediction of Alzheimer's disease in older Japanese: the Hisayama Study Reviewed International journal

Ohara T, Ninomiya T, Kubo M, Hirakawa Y, Doi Y, Hata J, Iwaki T, Kanba S, Kiyohara Y.

J Am Geriatr Soc   2011.6

Effectiveness of the salivary occult blood test as a screening method for periodontal status Reviewed International journal

Shimazaki Y, Akifusa S, Takeshita T, Shibata Y, Doi Y, Hata J, Ninomiya T, Hirakawa Y, Kiyohara Y, Yamashita Y.

J Periodontol   2011.4

Body mass index and stroke incidence in a Japanese community: the Hisayama Study Reviewed

Yonemoto K, Doi Y, Hata J, Ninomiya T, Fukuhara M, Ikeda F, Mukai N, Iida M, Kiyohara Y.

Hypertens Res   2011.2

Albuminuria as a risk factor for peripheral arterial disease in a general population: the Hisayama Study Reviewed

Usui T, Ninomiya T, Nagata M, Doi Y, Hata J, Fukuhara M, Kiyohara Y.

J Atheroscler Thromb   2011.1

Trends in prevalence of Alzheimer's disease and vascular dementia in a Japanese community: the Hisayama Study Reviewed International journal

Sekita A, Ninomiya T, Tanizaki Y, Doi Y, Hata J, Yonemoto K, Arima H, Sasaki K, Iida M, Iwaki T, Kanba S, Kiyohara Y.

Acta Psychiatr Scand   2010.10

Circulating resistin is increased with decreasing renal function in a general Japanese population: the Hisayama Study Reviewed International journal

Kawamura R, Doi Y, Osawa H, Ninomiya T, Hata J, Yonemoto K, Tanizaki Y, Iida M, Makino H, Kiyohara Y.

Nephrol Dial Transplant   2010.10

QT interval prolongation and the risks of stroke and coronary heart disease in a general Japanese population: the Hisayama Study Reviewed

Maebuchi D, Arima H, Doi Y, Ninomiya T, Yonemoto K, Tanizaki Y, Kubo M, Hata J, Matsumura K, Iida M, Kiyohara Y.

Hypertens Res   2010.9

Trends in the prevalence of chronic kidney disease and its risk factors in a general Japanese population: the Hisayama Study Reviewed International journal

Nagata M, Ninomiya T, Doi Y, Yonemoto K, Kubo M, Hata J, Tsuruya K, Iida M, Kiyohara Y.

Nephrol Dial Transplant   2010.8

Insulin resistance is associated with the pathology of Alzheimer disease: the Hisayama Study Reviewed International journal

Matsuzaki T, Sasaki K, Tanizaki Y, Hata J, Fujimi K, Matsui Y, Sekita A, Suzuki SO, Kanba S, Kiyohara Y, Iwaki T.

Neurology   2010.8

Association study of the polymorphisms on chromosome 12p13 with atherothrombotic stroke in the Japanese population Reviewed International journal

Matsushita T, Umeno J, Hirakawa Y, Yonemoto K, Ashikawa K, Amitani H, Ninomiya T, Hata J, Doi Y, Kitazono T, Iida M, Nakamura Y, Kiyohara Y, Kubo M.

J Hum Genet   2010.7

Functional SNP of ARHGEF10 confers risk of atherothrombotic stroke Reviewed International journal

Matsushita T, Ashikawa K, Yonemoto K, Hirakawa Y, Hata J, Amitani H, Doi Y, Ninomiya T, Kitazono T, Ibayashi S, Iida M, Nakamura Y, Kiyohara Y, Kubo M.

Hum Mol Genet   2010.3

Impact of glucose tolerance status on development of ischemic stroke and coronary heart disease in a general Japanese population: the Hisayama Study Reviewed International journal

Doi Y, Ninomiya T, Hata J, Fukuhara M, Yonemoto K, Iwase M, Iida M, Kiyohara Y.

Stroke   2010.2

Impact of blood pressure levels on different types of stroke: the Hisayama Study Reviewed International journal

Arima H, Tanizaki Y, Yonemoto K, Doi Y, Ninomiya T, Hata J, Fukuhara M, Matsumura K, Iida M, Kiyohara Y.

J Hypertens   2009.12

Development and validation of a cardiovascular risk prediction model for Japanese: the Hisayama Study Reviewed

Arima H, Yonemoto K, Doi Y, Ninomiya T, Hata J, Tanizaki Y, Fukuhara M, Matsumura K, Iida M, Kiyohara Y.

Hypertens Res   2009.12

Impact of metabolic syndrome compared with impaired fasting glucose on the development of type 2 diabetes in a general Japanese population: the Hisayama Study Reviewed International journal

Mukai N, Doi Y, Ninomiya T, Hata J, Yonemoto K, Iwase M, Iida M, Kiyohara Y.

Diabetes Care   2009.12

Diabetes and hypertension markedly increased the risk of ischemic stroke associated with high serum resistin concentration in a general Japanese population: the Hisayama Study Reviewed International journal

Osawa H, Doi Y, Makino H, Ninomiya T, Yonemoto K, Kawamura R, Hata J, Tanizaki Y, Iida M, Kiyohara Y.

Cardiovasc Diabetol   2009.11

Flow volume and cross-sectional area of the extracranial vertebral arteries and its relation to vascular lesions or anatomical variations in the posterior circulation Reviewed International journal

Wakugawa Y, Sugimori H, Nakane H, Hata J, Irie K, Kitazono T, Iida M.

Ultrasound Med Biol   2009.7

Proposed criteria for metabolic syndrome in Japanese based on prospective evidence: the Hisayama Study Reviewed International journal

Doi Y, Ninomiya T, Hata J, Yonemoto K, Arima H, Kubo M, Tanizaki Y, Iwase M, Iida M, Kiyohara Y.

Stroke   2009.4

Lack of association between variations of PDE4D and ischemic stroke in the Japanese population Reviewed International journal

Matsushita T, Kubo M, Yonemoto K, Ninomiya T, Ashikawa K, Liang B, Hata J, Doi Y, Kitazono T, Ibayashi S, Iida M, Kiyohara Y, Nakamura Y.

Stroke   2009.4

Hyperglycemia increases risk of gastric cancer posed by helicobacter pylori infection: a population-based cohort study Reviewed International journal

Ikeda F, Doi Y, Yonemoto K, Ninomiya T, Kubo M, Shikata K, Hata J, Tanizaki Y, Matsumoto T, Iida M, Kiyohara Y.

Gastroenterology   2009.4

LDL cholesterol and the development of stroke subtypes and coronary heart disease in a general Japanese population: the Hisayama Study Reviewed International journal

Imamura T, Doi Y, Arima H, Yonemoto K, Hata J, Kubo M, Tanizaki Y, Ibayashi S, Iida M, Kiyohara Y.

Stroke   2009.2

Seroprevalence of herpes simplex virus 1 and 2 in a population-based cohort in Japan Reviewed

Doi Y, Ninomiya T, Hata J, Yonemoto K, Tanizaki Y, Arima H, Liu Y, Rahman M, Iida M, Kiyohara Y.

J Epidemiol   2009.1

Fasting plasma glucose cutoff for diagnosis of diabetes in a Japanese population Reviewed International journal

Doi Y, Kubo M, Yonemoto K, Ninomiya T, Iwase M, Arima H, Hata J, Tanizaki Y, Iida M, Kiyohara Y.

J Clin Endocrinol Metab   2008.9

High-sensitivity C-reactive protein and coronary heart disease in a general population of Japanese: the Hisayama Study Reviewed International journal

Arima H, Kubo M, Yonemoto K, Doi Y, Ninomiya T, Tanizaki Y, Hata J, Matsumura K, Iida M, Kiyohara Y.

Arterioscler Thromb Vasc Biol   2008.7

Polymorphism in the sorbin and SH3-domain-containing-1 (SORBS1) gene and the risk of brain infarction in the Japanese population: the Fukuoka Stroke Registry and the Hisayama study Reviewed International journal

Hagiwara N, Kitazono T, Kamouchi M, Kuroda J, Ago T, Hata J, Ninomiya T, Ooboshi H, Kumai Y, Yoshimura S, Tamaki K, Fujii K, Nagao T, Okada Y, Toyoda K, Nakane H, Sugimori H, Yamashita Y, Wakugawa Y, Kubo M, Tanizaki Y, Kiyohara Y, Ibayashi S, Iida M; Fukuoka Stroke Registry; Hisayama Study.

Eur J Neurol   2008.5

Polymorphisms in the lymphotoxin alpha gene and the risk of ischemic stroke in the Japanese population. the Fukuoka Stroke Registry and the Hisayama Study Reviewed International journal

Hagiwara N, Kitazono T, Kamouchi M, Kuroda J, Ago T, Hata J, Ninomiya T, Ooboshi H, Kumai Y, Yoshimura S, Tamaki K, Fujii K, Nagao T, Okada Y, Toyoda K, Nakane H, Sugimori H, Yamashita Y, Wakugawa Y, Kubo M, Tanizaki Y, Kiyohara Y, Ibayashi S, Iida M.

Cerebrovasc Dis   2008.1

Impact of Kir6.2 E23K polymorphism on the development of type 2 diabetes in a general Japanese population: the Hisayama Study Reviewed International journal

Doi Y, Kubo M, Ninomiya T, Yonemoto K, Iwase M, Arima H, Hata J, Tanizaki Y, Iida M, Kiyohara Y.

Diabetes   2007.11

A nonsynonymous SNP in PRKCH (protein kinase C eta) increases the risk of cerebral infarction Reviewed International journal

Kubo M, Hata J, Ninomiya T, Matsuda K, Yonemoto K, Nakano T, Matsushita T, Yamazaki K, Ohnishi Y, Saito S, Kitazono T, Ibayashi S, Sueishi K, Iida M, Nakamura Y, Kiyohara Y.

Nat Genet   2007.2

Decreasing incidence of lacunar vs other types of cerebral infarction in a Japanese population Reviewed International journal

Kubo M, Kiyohara Y, Ninomiya T, Tanizaki Y, Yonemoto K, Doi Y, Hata J, Oishi Y, Shikata K, Iida M.

Neurology   2006.5

C-reactive protein and risk of first-ever ischemic and hemorrhagic stroke in a general Japanese population: the Hisayama Study Reviewed International journal

Wakugawa Y, Kiyohara Y, Tanizaki Y, Kubo M, Ninomiya T, Hata J, Doi Y, Okubo K, Oishi Y, Shikata K, Yonemoto K, Maebuchi D, Ibayashi S, Iida M.

Stroke   2006.1

Chronic kidney disease and cardiovascular disease in a general Japanese population: the Hisayama Study Reviewed International journal

Ninomiya T, Kiyohara Y, Kubo M, Tanizaki Y, Doi Y, Okubo K, Wakugawa Y, Hata J, Oishi Y, Shikata K, Yonemoto K, Hirakata H, Iida M.

Kidney Int   2005.7

Hyperhomocysteinemia and the development of chronic kidney disease in a general population: the Hisayama Study Reviewed International journal

Ninomiya T, Kiyohara Y, Kubo M, Tanizaki Y, Tanaka K, Okubo K, Nakamura H, Hata J, Oishi Y, Kato I, Hirakata H, Iida M.

Am J Kidney Dis   2004.9

日本人を対象とした動脈硬化性疾患の新しい発症リスク予測モデル：久山町研究 Invited

秦淳、本田貴紀、陳三妹、二宮利治

第70回日本心臓病学会学術集会  2022.9 

脳卒中の危険因子とその予防 Invited

秦淳、二宮利治

第54回日本動脈硬化学会総会・学術集会  2022.7 

久山町研究を基盤とした脳梗塞のゲノム疫学研究 Invited

秦淳，二宮利治

第57回日本循環器病予防学会学術集会  2021.6 

脳卒中発症の危険因子としてのバイオマーカー：久山町研究 Invited

秦淳，二宮利治

第46回日本脳卒中学会学術集会  2021.3 

日本人地域住民における動脈硬化性疾患とその危険因子の推移：久山町研究 Invited

秦淳，二宮利治

第52回日本動脈硬化学会総会・学術集会  2020.7 

高血圧と心血管病・認知症の疫学：久山町研究 Invited

秦淳

第35回日本脳神経血管内治療学会学術総会  2019.11 

糖尿病，脳梗塞，認知症のゲノム疫学研究 Invited

秦淳，二宮利治

第51回日本動脈硬化学会総会・学術集会  2019.7 

福岡県久山町における認知症の疫学研究 Invited

秦淳，小原知之，二宮利治

第8回臨床高血圧フォーラム，第55回日本循環器病予防学会学術集会  2019.5 

脳卒中の疫学 Invited

秦淳

第44回日本脳卒中学会学術集会  2019.3 

心血管病の新しい危険因子としてのバイオマーカー：　久山町研究 Invited

秦淳，二宮利治

第64回日本心臓病学会学術集会  2016.9 

性別・年齢階級別にみた脳卒中とその危険因子の疫学 Invited

秦淳

第42回日本脳卒中学会学術総会  2017.3 

福岡県久山町における認知症の疫学研究コホート研究から得られた認知症に関する最近の知見

秦淳，小原知之，二宮利治

第55回日本循環器病予防学会学術集会  2019.5 

食環境と健康長寿のフロンティア. 生活習慣病のオーダーメイド予防：久山町研究. Invited

秦淳，久保充明，清原裕

日本栄養・食糧学会九州・沖縄支部. 佐賀大学産学官連携推進機構および佐賀大学医食同源プロジェクト合同公開講座  2007.4 

久山町研究を基盤とした脳梗塞のゲノムワイド関連遺伝子研究 Invited

秦淳，清原裕

第63回日本臨床眼科学会・第10回眼科DNAチップ研究会  2009.10 

久山町研究を基盤とした脳梗塞のゲノムワイド関連研究 Invited

秦淳，久保充明，清原裕

第80回日本衛生学会学術総会  2010.5 

一般住民における心房細動の特徴と予後 Invited

秦淳，後藤聖司，福原正代，清原裕

第37回日本脳卒中学会総会  2012.4 

Stroke epidemiology in Japan: the Hisayama Study Invited International conference

2nd Asia Pacific Stroke Conference  2012.9 

Diabetes mellitus as a risk factor for cancer: the Hisayama Study Invited

2013.10 

脳卒中のバイオマーカー：久山町研究 Invited

秦淳，清原裕

第39回日本脳卒中学会総会  2014.3 

心血管病と認知症の疫学：久山町研究 Invited

秦淳，清原裕

第56回日本老年医学会学術集会  2014.6 

日本人における心血管病危険因子の時代的変化と特徴：久山町研究 Invited

秦淳，清原裕

第17回日本栓子検出と治療学会  2014.10 

糖代謝異常・脂質異常症と脳卒中の疫学：久山町研究 Invited

秦淳，清原裕

第40回日本脳卒中学会総会  2015.3 

動脈硬化性疾患の新しい危険因子：久山町研究から Invited

秦淳，清原裕

第47回日本動脈硬化学会総会・学術集会  2015.7 

高血圧と心臓合併症の疫学：久山町研究を中心に Invited

秦淳，清原裕，二宮利治

第38回日本高血圧学会総会  2015.10 

Risk factors for carotid atherosclerosis: the Hisayama Study. Invited

2017.7 

網羅的ゲノム解析による脳梗塞関連遺伝子の探索 Invited

秦淳

第43回日本脳卒中学会学術総会  2018.3 

血清angiopoietin-like protein 2 (ANGPTL2)濃度と死因別死亡の関連：久山町研究

秦淳、坂田智子、古田芳彦、大石絵美、本田貴紀、柴田舞欧、北園孝成、尾池雄一、二宮利治

第60回日本循環器病予防学会学術集会  2024.5 

日本人地域住民における心房細動発症のリスク予測モデルの開発：久山町研究

秦淳，坂田智子，永田拓也，平川洋一郎，大石絵美，本田貴紀，吉田大悟，北園孝成，二宮利治

第55回日本循環器病予防学会学術集会  2019.5 

βアラニン血中濃度と認知症発症の関連：久山町研究

秦淳，小原知之，片倉喜範，清水邦義，山下俊太郎，吉田大悟，本田貴紀，平川洋一郎，柴田舞欧，坂田智子，北園孝成，久原哲，二宮利治

第25回日本未病システム学会学術総会  2018.10 

地域住民における白衣高血圧，仮面高血圧とアルブミン尿症の関連：久山町研究 Invited

秦淳，福原正代，坂田智子，有馬久富，平川洋一郎，米本孝二，向井直子，北園孝成，清原裕，二宮利治

第41回日本高血圧学会総会  2018.9 

慢性期循環器疾患患者における死亡リスク予測モデルの開発：バイオバンク・ジャパン

秦淳，永井亜貴子，平田真，鎌谷洋一郎，玉腰暁子，山縣然太朗，武藤香織，松田浩一，久保充明，清原裕，二宮利治

第27回日本疫学会学術総会  2017.1 

経口腔エコーが有用であった内頚動脈狭窄症の一例

秦　淳，岸川和裕，永富葉子，荒川修治，鴨打正浩，岡田　靖，井上　亨，安森弘太郎

第148回日本神経学会九州地方会  1999.12 

肝細胞癌に対する皮下埋め込み型動注システム留置中に発症した脳梗塞４症例の検討

秦　淳，竹迫仁則，中村　宏，古賀政利，六倉和生，井上　剛，朔　義亮

第151回日本神経学会九州地方会  2000.9 

肝悪性腫瘍に対する皮下植え込み型動注システムに発症した脳梗塞症例の検討

秦　淳，竹迫仁則，中村　宏，井上　剛，古賀政利，六倉和生，朔　義亮，井林雪郎

第26回日本脳卒中学会総会  2001.3 

地域住民における脳卒中の病型別再発率の検討：久山町研究

秦淳，谷崎弓裕，清原裕，加藤功，久保充明，田中圭一，大久保賢，中村秀敏，尾石義謙，井林雪郎，飯田三雄

第28回日本脳卒中学会総会  2003.3 

純粋型レビー小体型痴呆の１剖検例

秦淳，谷崎弓裕，脇坂義信，清原裕，加藤功，久保充明，大久保賢，田中圭一，中村秀敏，尾石義謙，飯田三雄

第13回日本老年医学会九州地方会  2003.3 

一般住民におけるメタボリックシンドロームがタイプ別脳梗塞の発症に及ぼす影響：久山町研究

秦淳，谷崎弓裕，土井康文，二宮利治，有馬久富，今村剛，米本孝二，清原裕，井林雪郎，飯田三雄

第18回日本疫学会学術総会  2008.1 

メタボリックシンドロームは全ての脳梗塞タイプの有意な危険因子である：久山町研究

秦淳，谷崎弓裕，土井康文，二宮利治，有馬久富，今村剛，米本孝二，井林雪郎，飯田三雄，清原裕

第33回日本脳卒中学会総会  2008.3 

AGTRL1遺伝子の一塩基多型(SNP)が脳梗塞の発症に及ぼす影響

秦淳，久保充明，二宮利治，米本孝二，松下知永，北園孝成，井林雪郎，飯田三雄，中村祐輔，清原裕

第33回日本脳卒中学会総会  2008.3 

新規脳梗塞関連遺伝子AGTRL1の同定と機能解析 Invited

秦淳，久保充明，北園孝成，飯田三雄，中村祐輔，清原裕

第9回日本分子脳神経外科学会  2008.8 

一般住民における喫煙が脳卒中と虚血性心疾患の発症に及ぼす影響：久山町研究

秦淳，土井康文，谷崎弓裕，今村剛，福原正代，米本孝二，北園孝成，飯田三雄，清原裕

第34回日本脳卒中学会総会  2009.3 

地域住民における喫煙と虚血性心疾患・脳卒中発症との関連：久山町研究

秦淳，土井康文，谷崎弓裕，今村剛，福原正代，米本孝二，北園孝成，飯田三雄，清原裕

第45回日本循環器病予防学会・日本循環器管理研究協議会総会  2009.6 

急性期脳出血に対する積極的降圧療法がmidline shiftと水頭症の進行に及ぼす影響：INTERACT試験

秦淳，Fullard K，Delcourt C，HeeleyE，有馬久富，Anderson C

第36回日本脳卒中学会総会  2011.3 

2型糖尿病患者における腎機能増悪予測モデル：ADVANCE試験

秦淳，Jardin M，有馬久富，二宮利治，Zongas S，Perkovic V，Anderson C，Woodward M，Cass A，Patel A，Chalmers J

第34回日本高血圧学会総会  2011.10 

一般住民における脳卒中、虚血性心疾患罹患率とその危険因子の50年にわたる時代的推移：久山町研究

秦淳，二宮利治，平川洋一郎，永田雅治，向井直子，後藤聖司，福原正代，鴨打正浩，北園孝成，清原裕

第38回日本脳卒中学会総会  2013.3 

Angiopoietin-like protein 2 (ANGPTL2) and the risk of cardiovascular disease in a general Japanese population: the Hisayama Study

2015.4 

脳梗塞のゲノム疫学研究． Reviewed

秦　淳、二宮利治

医学のあゆみ   2021.7

脳梗塞のゲノム疫学：久山町研究

秦　淳、二宮　利治

2021.2

脳卒中の疫学

秦　淳，二宮　利治

日本臨牀   2019.6

脂質異常症と動脈硬化性疾患の疫学研究

秦　淳，二宮　利治

2018.6

地域住民における白衣高血圧，仮面高血圧とアルブミン尿症の関連：久山町研究

秦　淳

血圧   2018.5

地域住民を対象とした疫学研究

秦 淳, 小原知之、二宮利治

日本医師会雑誌　生涯教育シリーズ   2017.6

糖代謝異常・脂質異常症と脳卒中の疫学：久山町研究

秦 淳, 清原　裕

脳卒中   2016.11

ヘマトクリットと心血管病発症の関係：久山町研究

後藤　聖司, 秦 淳, 清原　裕

血圧   2016.4

脳卒中のバイオマーカー：久山町研究

秦　淳，清原　裕

脳卒中   2015.9

糖尿病と認知症の疫学

秦　淳，清原　裕

糖尿病診療マスター   2015.8

動脈硬化の診断と治療の現況と展望．久山町研究から

大石絵美，秦　淳，清原　裕

月刊カレントテラピー   2015.5

Japan Mibyou Association

Japanese Society of Neurology

Japanese Society of Hypertension

Japanese Society of Cardiovascular Disease Prevention

Japanese Circulation Society

Japan Stroke Society

Japanese Society of Internal Medicine

Society for Clinical Epidemiology

座長

第46回日本脳卒中学会学術集会  （ 福岡市 ） 2021.3 - 2021.4

Screening of academic papers

Role(s)： Peer review

2021

Screening of academic papers

Role(s)： Peer review

2020

実行委員

日本臨床疫学会第3回年次学術大会  （ 福岡市 ） 2019.9

Screening of academic papers

Role(s)： Peer review

2019

Screening of academic papers

Role(s)： Peer review

2018

脳卒中

Role(s)： Peer review

2017.6 - Present

座長（Chairmanship）

第27回日本老年医学会九州地方会  （ 福岡市 ） 2017.3

Screening of academic papers

Role(s)： Peer review

2017

副実行委員長

第23回日本未病システム学会学術総会  （ 福岡市 ） 2016.11 - 2017.11

Journal of Stroke and Cerebrovascular Diseases International contribution

Role(s)： Peer review

2015.10 - 2019.12

腸内細菌叢と生活習慣病・認知症・うつ病発症に関する地域コホート研究：久山町研究

Grant number：21H03200  2021 - 2023

日本学術振興会  科学研究費助成事業  基盤研究(B)

地域住民における心房細動発症のバイオマーカーと遺伝要因：久山町研究

2020.4 - 2023.3

地域住民における心房細動発症のバイオマーカーと遺伝要因：久山町研究

Grant number：20K10503  2020 - 2022

日本学術振興会  科学研究費助成事業  基盤研究(C)

地域高齢住民におけるサルコペニアと認知症発症との関連：久山町研究

2017.4 - 2020.3

九州大学（日本） 

地域高齢住民におけるサルコペニアと認知症発症との関連：久山町研究

Grant number：17K01853  2017 - 2019

日本学術振興会  科学研究費助成事業  基盤研究(C)

健康長寿社会の実現を目指した大規模認知症コホート研究

2016.4 - 2021.3

久山町高齢者におけるMRIを基盤にした認知症・うつ病発症の前向きコホート研究

2016.4 - 2019.3

九州大学 

健康長寿社会の実現を目指した大規模認知症コホート研究

2016 - 2020

国立研究開発法人日本医療研究開発機構・認知症研究開発事業

久山町高齢者におけるMRIを基盤にした認知症・うつ病発症の前向きコホート研究

Grant number：16H02644  2016 - 2018

日本学術振興会  科学研究費助成事業  基盤研究(A)

NCD-RisC International coauthorship

2015.12

MEGASTROKE International coauthorship

2015.11

久山町一般住民におけるむずむず脚症候群と脳心血管病についての検討

2015.4 - 2018.3

九州大学 

健康長寿社会の実現を目指した大規模認知症コホート研究の創設

2015.4 - 2016.3

九州大学 

久山町一般住民におけるむずむず脚症候群と脳心血管病についての検討

Grant number：15K08737  2015 - 2017

日本学術振興会  科学研究費助成事業  基盤研究(C)

健康長寿社会の実現を目指した大規模認知症コホート研究の創設

2015

国立研究開発法人日本医療研究開発機構・認知症研究開発事業

地域住民における余暇時の運動習慣および運動量が健康寿命に与える影響：久山町研究

2014.4 - 2017.3

九州大学 

日本人地域住民における心房細動の実態と危険因子に関する研究：久山町研究

2014.4 - 2017.3

九州大学 

日本人地域住民における心房細動の実態と危険因子に関する研究：久山町研究

Grant number：26460748  2014 - 2016

日本学術振興会  科学研究費助成事業  基盤研究(C)

地域住民における余暇時の運動習慣および運動量が健康寿命に与える影響：久山町研究

Grant number：26350895  2014 - 2016

日本学術振興会  科学研究費助成事業  基盤研究(C)